{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T10:54:25Z","timestamp":1790679265356,"version":"4.1.0"},"reference-count":178,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,9,1]],"date-time":"2023-09-01T00:00:00Z","timestamp":1693526400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,12]],"date-time":"2023-07-12T00:00:00Z","timestamp":1689120000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","em-consulte.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedicine & Pharmacotherapy"],"published-print":{"date-parts":[[2023,9]]},"DOI":"10.1016\/j.biopha.2023.115175","type":"journal-article","created":{"date-parts":[[2023,7,18]],"date-time":"2023-07-18T06:04:50Z","timestamp":1689660290000},"page":"115175","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Insights into the structure, functional perspective, and pathogenesis of ZIKV: an updated review"],"prefix":"10.1016","volume":"165","author":[{"given":"Eijaz Ahmed","family":"Bhat","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tufail","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nasreena","family":"Sajjad","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohit","family":"kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patrick","family":"Bron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopha.2023.115175_bib1","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.plipres.2016.09.005","article-title":"Lipids and flaviviruses, present and future perspectives for the control of dengue, Zika, and West Nile viruses","volume":"64","author":"Martin-Acebes","year":"2016","journal-title":"Prog. Lipid Res."},{"key":"10.1016\/j.biopha.2023.115175_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12985-016-0551-1","article-title":"Nucleotide composition of the Zika virus RNA genome and its codon usage","volume":"13","author":"van Hemert","year":"2016","journal-title":"Virol. J."},{"issue":"5","key":"10.1016\/j.biopha.2023.115175_bib3","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004702","article-title":"Zika virus: a new animal model for an arbovirus","volume":"10","author":"Aman","year":"2016","journal-title":"PLOS Negl. Trop. Dis."},{"issue":"2","key":"10.1016\/j.biopha.2023.115175_bib4","doi-asserted-by":"crossref","first-page":"269","DOI":"10.1099\/jgv.0.000381","article-title":"Zika virus: a previously slow pandemic spreads rapidly through the Americas","volume":"97","author":"Gatherer","year":"2016","journal-title":"J. Gen. Virol."},{"key":"10.1016\/j.biopha.2023.115175_bib5","first-page":"17","article-title":"Current and emerging pharmacotherapies for zika virus: a comprehensive review","author":"Noronha","year":"2023","journal-title":"Ind. J. Pharm. Drugs Stud."},{"issue":"5","key":"10.1016\/j.biopha.2023.115175_bib6","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0007443","article-title":"Pathogen blocking in Wolbachia-infected Aedes aegypti is not affected by Zika and dengue virus co-infection","volume":"13","author":"Caragata","year":"2019","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"8","key":"10.1016\/j.biopha.2023.115175_bib7","doi-asserted-by":"crossref","first-page":"565","DOI":"10.1038\/nrd.2017.33","article-title":"Broad-spectrum agents for flaviviral infections: dengue, Zika and beyond","volume":"16","author":"Boldescu","year":"2017","journal-title":"Nat. Rev. Drug Discov."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13071-017-2559-9","article-title":"Mosquito-borne arboviruses of African origin: review of key viruses and vectors","volume":"11","author":"Braack","year":"2018","journal-title":"Parasites Vectors"},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib9","first-page":"1","article-title":"Prevention and control of Zika as a mosquito-borne and sexually transmitted disease: a mathematical modeling analysis","volume":"6","author":"Gao","year":"2016","journal-title":"Sci. Rep."},{"issue":"7","key":"10.1016\/j.biopha.2023.115175_bib10","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.3201\/eid2207.151990","article-title":"A literature review of Zika virus","volume":"22","author":"Plourde","year":"2016","journal-title":"Emerg. Infect. Dis."},{"issue":"11","key":"10.1016\/j.biopha.2023.115175_bib11","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1080\/1744666X.2016.1193006","article-title":"Guillain-Barr\u00e9 syndrome: causes, immunopathogenic mechanisms and treatment","volume":"12","author":"Jasti","year":"2016","journal-title":"Expert Rev. Clin. Immunol."},{"issue":"2","key":"10.1016\/j.biopha.2023.115175_bib12","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1097\/DBP.0000000000000722","article-title":"Early gross motor development among brazilian children with microcephaly born right after Zika Virus Infection outbreak","volume":"41","author":"Ventura","year":"2020","journal-title":"J. Dev. Behav. Pediatr."},{"issue":"8","key":"10.1016\/j.biopha.2023.115175_bib13","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1056\/NEJMoa2101195","article-title":"Mortality from congenital Zika syndrome\u2014nationwide cohort study in Brazil","volume":"386","author":"Paixao","year":"2022","journal-title":"N. Engl. J. Med."},{"issue":"4","key":"10.1016\/j.biopha.2023.115175_bib14","doi-asserted-by":"crossref","first-page":"722","DOI":"10.3201\/eid2104.141707","article-title":"Zika virus infection, Philippines, 2012","volume":"21","author":"Alera","year":"2015","journal-title":"Emerg. Infect. Dis."},{"issue":"2","key":"10.1016\/j.biopha.2023.115175_bib15","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0002681","article-title":"Zika virus in Gabon (Central Africa)\u20132007: a new threat from Aedes albopictus?","volume":"8","author":"Grard","year":"2014","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.biopha.2023.115175_bib16","series-title":"zika virus disease: From origin to outbreak","author":"Qureshi","year":"2017"},{"issue":"5","key":"10.1016\/j.biopha.2023.115175_bib17","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1080\/14787210.2018.1466702","article-title":"Neurological complications of Zika virus infection","volume":"16","author":"Carod-Artal","year":"2018","journal-title":"Expert Rev. Anti-Infect. Ther."},{"issue":"10","key":"10.1016\/j.biopha.2023.115175_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0010812","article-title":"The global trends and regional differences in incidence of Zika virus infection and implications for Zika virus infection prevention","volume":"16","author":"Guo","year":"2022","journal-title":"PLOS Negl. Trop. Dis."},{"key":"10.1016\/j.biopha.2023.115175_bib19","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1007\/978-1-0716-0581-3_4","article-title":"Droplet digital PCR and immunohistochemistry techniques to detect Zika virus in the central nervous system of mice","author":"Enlow","year":"2020","journal-title":"Zika Virus.: Methods Protoc."},{"key":"10.1016\/j.biopha.2023.115175_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2021.12.196","article-title":"New insights into the recombinant proteins and monoclonal antibodies employed to immunodiagnosis and control of Zika virus infection: a review","author":"Magalh\u00e3es","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"issue":"3","key":"10.1016\/j.biopha.2023.115175_bib21","doi-asserted-by":"crossref","first-page":"e01413","DOI":"10.1128\/JCM.01413-18","article-title":"Evaluation of a rapid immunochromatographic assay and two enzyme-linked immunosorbent assays for detection of IgM-class Antibodies to Zika virus","volume":"57","author":"Granger","year":"2019","journal-title":"J. Clin. Microbiol."},{"issue":"3","key":"10.1016\/j.biopha.2023.115175_bib22","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0009195","article-title":"Zika virus-like particle vaccine protects AG129 mice and rhesus macaques against Zika virus","volume":"15","author":"Vang","year":"2021","journal-title":"PLoS Negl. Trop. Dis."},{"key":"10.1016\/j.biopha.2023.115175_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2020.128351","article-title":"A novel nucleic acid amplification system based on nano-gap embedded active disk resonators","volume":"320","author":"Lee","year":"2020","journal-title":"Sens. Actuators B: Chem."},{"issue":"9","key":"10.1016\/j.biopha.2023.115175_bib24","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0185340","article-title":"Rapid colorimetric detection of Zika virus from serum and urine specimens by reverse transcription loop-mediated isothermal amplification (RT-LAMP)","volume":"12","author":"Calvert","year":"2017","journal-title":"PloS One"},{"key":"10.1016\/j.biopha.2023.115175_bib25","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.coviro.2018.03.007","article-title":"CRISPR genetic screens to discover host\u2013virus interactions","volume":"29","author":"McDougall","year":"2018","journal-title":"Curr. Opin. Virol."},{"key":"10.1016\/j.biopha.2023.115175_bib26","first-page":"2023","article-title":"Pathogen-driven CRISPR screens identify TREX1 as a regulator of DNA self-sensing during influenza virus infection","author":"King","year":"2023","journal-title":"bioRxiv"},{"key":"10.1016\/j.biopha.2023.115175_bib27","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/978-1-0716-0581-3_17","article-title":"Discovery of Zika virus dependency and restriction factors using flow-based arrayed CRISPR screening for identification of targets (FACS-IT)","author":"McDougall","year":"2020","journal-title":"Zika Virus.: Methods Protoc."},{"issue":"4","key":"10.1016\/j.biopha.2023.115175_bib28","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1038\/s41564-020-00850-3","article-title":"Zika virus NS3 protease induces bone morphogenetic protein-dependent brain calcification in human fetuses","volume":"6","author":"Chen","year":"2021","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.biopha.2023.115175_bib29","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/j.puhe.2017.05.008","article-title":"The rise of Zika infection and microcephaly: what can we learn from a public health emergency?","volume":"150","author":"McCloskey","year":"2017","journal-title":"Public Health"},{"key":"10.1016\/j.biopha.2023.115175_bib30","series-title":"Mayo Clinic Proceedings","article-title":"Zika vaccine development: current status","author":"Poland","year":"2019"},{"issue":"2","key":"10.1016\/j.biopha.2023.115175_bib31","doi-asserted-by":"crossref","first-page":"266","DOI":"10.3390\/vaccines8020266","article-title":"Current status of Zika virus vaccines: successes and challenges","volume":"8","author":"Pattnaik","year":"2020","journal-title":"Vaccines"},{"key":"10.1016\/j.biopha.2023.115175_bib32","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.virol.2020.01.015","article-title":"Zika virus-spread, epidemiology, genome, transmission cycle, clinical manifestation, associated challenges, vaccine and antiviral drug development","volume":"543","author":"Pielnaa","year":"2020","journal-title":"Virology"},{"key":"10.1016\/j.biopha.2023.115175_bib33","unstructured":"Cases, T.-A., KEY MESSAGES\u2013ZIKA VIRUS DISEASE."},{"key":"10.1016\/j.biopha.2023.115175_bib34","doi-asserted-by":"crossref","first-page":"1469","DOI":"10.3389\/fmicb.2017.01469","article-title":"Advances in developing therapies to combat Zika virus: current knowledge and future perspectives","volume":"8","author":"Munjal","year":"2017","journal-title":"Front. Microbiol."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib35","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1080\/00034983.1949.11685396","article-title":"An outbreak of sylvan yellow fever in Uganda with Aedes (Stegomyia) africanus Theobald as principal vector and insect host of the virus","volume":"43","author":"Smithburn","year":"1949","journal-title":"Ann. Trop. Med. Parasitol."},{"issue":"3","key":"10.1016\/j.biopha.2023.115175_bib36","doi-asserted-by":"crossref","first-page":"372","DOI":"10.3390\/vaccines10030372","article-title":"Yellow fever: origin, epidemiology, preventive strategies and future prospects","volume":"10","author":"Gianchecchi","year":"2022","journal-title":"Vaccines"},{"issue":"3","key":"10.1016\/j.biopha.2023.115175_bib37","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1128\/CMR.00072-15","article-title":"Zika virus","volume":"29","author":"Musso","year":"2016","journal-title":"Clin. Microbiol. Rev."},{"issue":"4","key":"10.1016\/j.biopha.2023.115175_bib38","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1038\/s41559-019-0836-z","article-title":"Vector-borne transmission and evolution of Zika virus","volume":"3","author":"Guti\u00e9rrez-Bugallo","year":"2019","journal-title":"Nat. Ecol. Evol."},{"key":"10.1016\/j.biopha.2023.115175_bib39","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.preteyeres.2018.04.004","article-title":"Zika and the Eye: Pieces of a Puzzle","volume":"66","author":"de Oliveira Dias","year":"2018","journal-title":"Prog. Retin. eye Res."},{"issue":"7","key":"10.1016\/j.biopha.2023.115175_bib40","doi-asserted-by":"crossref","first-page":"e119","DOI":"10.1016\/S1473-3099(16)30010-X","article-title":"Zika virus: history of a newly emerging arbovirus","volume":"16","author":"Wikan","year":"2016","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.biopha.2023.115175_bib41","article-title":"The microcephaly epidemic and Zika virus: building knowledge in epidemiology","volume":"34","author":"Albuquerque","year":"2018","journal-title":"Cad. De. Saude Publica"},{"issue":"3","key":"10.1016\/j.biopha.2023.115175_bib42","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0009055","article-title":"Measuring the global burden of chikungunya and Zika viruses: A systematic review","volume":"15","author":"Puntasecca","year":"2021","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"4","key":"10.1016\/j.biopha.2023.115175_bib43","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1002\/ana.24748","article-title":"Zika virus: An emergent neuropathological agent","volume":"80","author":"White","year":"2016","journal-title":"Ann. Neurol."},{"issue":"2","key":"10.1016\/j.biopha.2023.115175_bib44","first-page":"187","article-title":"Zika virus infection of retinal cells and the developing mouse eye induces host responses that contrasts to the brain and dengue virus infection","volume":"29","author":"Cowell","year":"2023","journal-title":"J. Neuro Virol."},{"issue":"2","key":"10.1016\/j.biopha.2023.115175_bib45","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1001278","article-title":"NS2 protein of hepatitis C virus interacts with structural and non-structural proteins towards virus assembly","volume":"7","author":"Popescu","year":"2011","journal-title":"PLoS Pathog."},{"issue":"2","key":"10.1016\/j.biopha.2023.115175_bib46","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/j.antiviral.2013.03.008","article-title":"The flavivirus NS1 protein: molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker","volume":"98","author":"Muller","year":"2013","journal-title":"Antivir. Res."},{"key":"10.1016\/j.biopha.2023.115175_bib47","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.antiviral.2016.02.014","article-title":"The many faces of the flavivirus NS1 protein offer a multitude of options for inhibitor design","volume":"130","author":"Watterson","year":"2016","journal-title":"Antivir. Res."},{"issue":"2","key":"10.1016\/j.biopha.2023.115175_bib48","doi-asserted-by":"crossref","first-page":"888","DOI":"10.1006\/viro.1993.1198","article-title":"Dengue 2 virus NS2B and NS3 form a stable complex that can cleave NS3 within the helicase domain","volume":"193","author":"Arias","year":"1993","journal-title":"Virology"},{"key":"10.1016\/j.biopha.2023.115175_bib49","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1007\/s00018-018-2751-x","article-title":"Structure and function of Zika virus NS5 protein: perspectives for drug design","volume":"75","author":"Wang","year":"2018","journal-title":"Cell. Mol. life Sci."},{"issue":"12","key":"10.1016\/j.biopha.2023.115175_bib50","doi-asserted-by":"crossref","DOI":"10.1038\/cti.2016.72","article-title":"Dengue virus antibodies enhance Zika virus infection","volume":"5","author":"Paul","year":"2016","journal-title":"Clin. Transl. Immunol."},{"issue":"15","key":"10.1016\/j.biopha.2023.115175_bib51","doi-asserted-by":"crossref","first-page":"e00698","DOI":"10.1128\/JVI.00698-17","article-title":"Transposon mutagenesis of the Zika virus genome highlights regions essential for RNA replication and restricted for immune evasion","volume":"91","author":"Fulton","year":"2017","journal-title":"J. Virol."},{"issue":"6","key":"10.1016\/j.biopha.2023.115175_bib52","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.chom.2008.10.007","article-title":"A highly structured, nuclease-resistant, noncoding RNA produced by flaviviruses is required for pathogenicity","volume":"4","author":"Pijlman","year":"2008","journal-title":"Cell Host Microbe"},{"issue":"24","key":"10.1016\/j.biopha.2023.115175_bib53","doi-asserted-by":"crossref","first-page":"13486","DOI":"10.1128\/JVI.01104-12","article-title":"Noncoding flavivirus RNA displays RNA interference suppressor activity in insect and Mammalian cells","volume":"86","author":"Schnettler","year":"2012","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.biopha.2023.115175_bib54","doi-asserted-by":"crossref","first-page":"404","DOI":"10.3390\/v6020404","article-title":"Noncoding subgenomic flavivirus RNA: multiple functions in West Nile virus pathogenesis and modulation of host responses","volume":"6","author":"Roby","year":"2014","journal-title":"Viruses"},{"issue":"5","key":"10.1016\/j.biopha.2023.115175_bib55","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.3390\/ijms20051101","article-title":"Advances in Zika virus\u2013host cell interaction: Current knowledge and future perspectives","volume":"20","author":"Lee","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.biopha.2023.115175_bib56","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1016\/j.placenta.2020.09.062","article-title":"TAM and TIM receptors mRNA expression in Zika virus infected placentas","volume":"101","author":"Nobrega","year":"2020","journal-title":"Placenta"},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib57","doi-asserted-by":"crossref","first-page":"247","DOI":"10.3390\/v15010247","article-title":"Exploring the Expression and Function of cTyro3, a Candidate Zika Virus Receptor, in the Embryonic Chicken Brain and Inner Ear","volume":"15","author":"Negi","year":"2023","journal-title":"Viruses"},{"issue":"17","key":"10.1016\/j.biopha.2023.115175_bib58","doi-asserted-by":"crossref","first-page":"8880","DOI":"10.1128\/JVI.00354-15","article-title":"Biology of Zika virus infection in human skin cells","volume":"89","author":"Hamel","year":"2015","journal-title":"J. Virol."},{"issue":"11","key":"10.1016\/j.biopha.2023.115175_bib59","doi-asserted-by":"crossref","first-page":"1558","DOI":"10.1038\/s41564-017-0016-3","article-title":"Asian Zika virus strains target CD14+ blood monocytes and induce M2-skewed immunosuppression during pregnancy","volume":"2","author":"Foo","year":"2017","journal-title":"Nat. Microbiol."},{"issue":"5","key":"10.1016\/j.biopha.2023.115175_bib60","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0092-8674(00)80694-7","article-title":"DC-SIGN, a dendritic cell\u2013specific HIV-1-binding protein that enhances trans-infection of T cells","volume":"100","author":"Geijtenbeek","year":"2000","journal-title":"Cell"},{"issue":"8","key":"10.1016\/j.biopha.2023.115175_bib61","doi-asserted-by":"crossref","first-page":"2024","DOI":"10.1073\/pnas.1620558114","article-title":"AXL-dependent infection of human fetal endothelial cells distinguishes Zika virus from other pathogenic flaviviruses","volume":"114","author":"Richard","year":"2017","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"5","key":"10.1016\/j.biopha.2023.115175_bib62","doi-asserted-by":"crossref","first-page":"591","DOI":"10.1016\/j.stem.2016.03.012","article-title":"Expression analysis highlights AXL as a candidate Zika virus entry receptor in neural stem cells","volume":"18","author":"Nowakowski","year":"2016","journal-title":"Cell Stem Cell"},{"issue":"2","key":"10.1016\/j.biopha.2023.115175_bib63","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.stem.2016.04.014","article-title":"Zika virus depletes neural progenitors in human cerebral organoids through activation of the innate immune receptor TLR3","volume":"19","author":"Dang","year":"2016","journal-title":"Cell Stem Cell"},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib64","article-title":"Gas6 stimulates angiogenesis of human retinal endothelial cells and of zebrafish embryos via ERK1\/2 signaling","volume":"9","author":"Kim","year":"2014","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.biopha.2023.115175_bib65","doi-asserted-by":"crossref","first-page":"e01372","DOI":"10.1128\/mBio.01372-19","article-title":"Axl promotes zika virus entry and modulates the antiviral state of human sertoli cells","volume":"10","author":"Strange","year":"2019","journal-title":"MBio"},{"issue":"6","key":"10.1016\/j.biopha.2023.115175_bib66","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1038\/icb.2013.22","article-title":"Breakdown of immune homeostasis in the testis of mice lacking Tyro3, Axl and Mer receptor tyrosine kinases","volume":"91","author":"Zhang","year":"2013","journal-title":"Immunol. Cell Biol."},{"issue":"6","key":"10.1016\/j.biopha.2023.115175_bib67","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1002\/pd.5446","article-title":"Zika virus during pregnancy: From maternal exposure to congenital Zika virus syndrome","volume":"39","author":"Pomar","year":"2019","journal-title":"Prenat. Diagn."},{"issue":"5","key":"10.1016\/j.biopha.2023.115175_bib68","doi-asserted-by":"crossref","first-page":"593","DOI":"10.1016\/j.stem.2016.08.005","article-title":"Zika virus infects neural progenitors in the adult mouse brain and alters proliferation","volume":"19","author":"Li","year":"2016","journal-title":"Cell Stem Cell"},{"issue":"4","key":"10.1016\/j.biopha.2023.115175_bib69","article-title":"Potential mechanisms of Zika\u2010linked microcephaly","volume":"6","author":"Merfeld","year":"2017","journal-title":"Wiley Interdiscip. Rev.: Dev. Biol."},{"key":"10.1016\/j.biopha.2023.115175_bib70","unstructured":"Pandey, H.S. and P. Seth, Interplay between Zika virus-induced autophagy and neural stem cell fate determination. 2023."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib71","doi-asserted-by":"crossref","first-page":"12774","DOI":"10.1038\/s41598-018-31149-3","article-title":"Zika virus impairs the development of blood vessels in a mouse model of congenital infection","volume":"8","author":"Garcez","year":"2018","journal-title":"Sci. Rep."},{"issue":"11","key":"10.1016\/j.biopha.2023.115175_bib72","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1056\/NEJMoa1709481","article-title":"Pregnancy outcomes after ZIKV infection in French territories in the Americas","volume":"378","author":"Hoen","year":"2018","journal-title":"N. Engl. J. Med."},{"issue":"22","key":"10.1016\/j.biopha.2023.115175_bib73","doi-asserted-by":"crossref","first-page":"3627","DOI":"10.3390\/cells11223627","article-title":"Decreased CSTB, RAGE, and Axl receptor are associated with zika infection in the human placenta","volume":"11","author":"Borges-V\u00e9lez","year":"2022","journal-title":"Cells"},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib74","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/srep35296","article-title":"ZIKA virus reveals broad tissue and cell tropism during the first trimester of pregnancy","volume":"6","author":"El Costa","year":"2016","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib75","doi-asserted-by":"crossref","first-page":"60","DOI":"10.5858\/arpa.2016-0406-SA","article-title":"Laboratory diagnosis of Zika virus infection","volume":"141","author":"Landry","year":"2017","journal-title":"Arch. Pathol. Lab. Med."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib76","doi-asserted-by":"crossref","first-page":"e00119","DOI":"10.1128\/cmr.00119-22","article-title":"Agnostic sequencing for detection of viral pathogens","volume":"36","author":"Gauthier","year":"2023","journal-title":"Clin. Microbiol. Rev."},{"issue":"11","key":"10.1016\/j.biopha.2023.115175_bib77","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1016\/S1473-3099(17)30444-9","article-title":"Effect of acute Zika virus infection on sperm and virus clearance in body fluids: a prospective observational study","volume":"17","author":"Joguet","year":"2017","journal-title":"Lancet Infect. Dis."},{"issue":"7633","key":"10.1016\/j.biopha.2023.115175_bib78","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1038\/nature20556","article-title":"Zika virus infection damages the testes in mice","volume":"540","author":"Govero","year":"2016","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.biopha.2023.115175_bib79","doi-asserted-by":"crossref","DOI":"10.1016\/j.cell.2016.08.004","article-title":"Vaginal exposure to Zika virus during pregnancy leads to fetal brain infection","volume":"166","author":"Yockey","year":"2016","journal-title":"Cell"},{"issue":"12","key":"10.1016\/j.biopha.2023.115175_bib80","doi-asserted-by":"crossref","first-page":"3208","DOI":"10.1016\/j.celrep.2016.08.079","article-title":"Zika virus infection in mice causes panuveitis with shedding of virus in tears","volume":"16","author":"Miner","year":"2016","journal-title":"Cell Rep."},{"issue":"5","key":"10.1016\/j.biopha.2023.115175_bib81","doi-asserted-by":"crossref","first-page":"233","DOI":"10.3390\/v10050233","article-title":"Probing molecular insights into Zika virus\u2013host interactions","volume":"10","author":"Lee","year":"2018","journal-title":"Viruses"},{"issue":"8","key":"10.1016\/j.biopha.2023.115175_bib82","doi-asserted-by":"crossref","first-page":"4275","DOI":"10.1128\/JVI.03287-13","article-title":"Role of phosphatidylserine receptors in enveloped virus infection","volume":"88","author":"Morizono","year":"2014","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.biopha.2023.115175_bib83","doi-asserted-by":"crossref","first-page":"324","DOI":"10.1016\/j.celrep.2016.12.045","article-title":"Axl mediates ZIKA virus entry in human glial cells and modulates innate immune responses","volume":"18","author":"Meertens","year":"2017","journal-title":"Cell Rep."},{"issue":"10","key":"10.1016\/j.biopha.2023.115175_bib84","doi-asserted-by":"crossref","DOI":"10.1038\/cddis.2016.266","article-title":"ZIKA virus elicits P53 activation and genotoxic stress in human neural progenitors similar to mutations involved in severe forms of genetic microcephaly and p53","volume":"7","author":"Ghouzzi","year":"2016","journal-title":"Cell Death Dis."},{"issue":"5","key":"10.1016\/j.biopha.2023.115175_bib85","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/nri2303","article-title":"Immunobiology of the TAM receptors","volume":"8","author":"Lemke","year":"2008","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.biopha.2023.115175_bib86","doi-asserted-by":"crossref","first-page":"1350","DOI":"10.3389\/fmicb.2018.01350","article-title":"Zika virus non-structural protein 4A blocks the RLR-MAVS signaling","volume":"9","author":"Ma","year":"2018","journal-title":"Front. Microbiol."},{"issue":"7","key":"10.1016\/j.biopha.2023.115175_bib87","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1016\/j.it.2005.05.004","article-title":"Viruses know it all: new insights into IFN networks","volume":"26","author":"Hengel","year":"2005","journal-title":"Trends Immunol."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib88","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1038\/s41467-020-16086-y","article-title":"Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes","volume":"11","author":"Slonchak","year":"2020","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib89","first-page":"1","article-title":"Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro","volume":"3","author":"Wu","year":"2017","journal-title":"Cell Discov."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib90","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1038\/cmi.2014.127","article-title":"Emerging roles of interferon-stimulated genes in the innate immune response to hepatitis C virus infection","volume":"13","author":"Wong","year":"2016","journal-title":"Cell. Mol. Immunol."},{"issue":"6","key":"10.1016\/j.biopha.2023.115175_bib91","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1038\/sj.icb.7100100","article-title":"Toll\u2010like receptors, RIG\u2010I\u2010like RNA helicases and the antiviral innate immune response","volume":"85","author":"Thompson","year":"2007","journal-title":"Immunol. Cell Biol."},{"issue":"6","key":"10.1016\/j.biopha.2023.115175_bib92","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1016\/j.febslet.2013.01.052","article-title":"Negative regulation of TBK1-mediated antiviral immunity","volume":"587","author":"Zhao","year":"2013","journal-title":"FEBS Lett."},{"issue":"3","key":"10.1016\/j.biopha.2023.115175_bib93","doi-asserted-by":"crossref","first-page":"e00452","DOI":"10.1128\/mBio.00452-17","article-title":"A novel agonist of the TRIF pathway induces a cellular state refractory to replication of Zika, chikungunya, and dengue viruses","volume":"8","author":"Pryke","year":"2017","journal-title":"MBio"},{"key":"10.1016\/j.biopha.2023.115175_bib94","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.virol.2023.03.016","article-title":"A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation","volume":"583","author":"Acchioni","year":"2023","journal-title":"Virology"},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib95","doi-asserted-by":"crossref","first-page":"489","DOI":"10.3390\/ijms23010489","article-title":"Mechanisms of viral degradation of cellular signal transducer and activator of transcription 2","volume":"23","author":"Barik","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"3","key":"10.1016\/j.biopha.2023.115175_bib96","doi-asserted-by":"crossref","first-page":"263","DOI":"10.3390\/vaccines9030263","article-title":"Perspectives on new vaccines against arboviruses using insect-specific viruses as platforms","volume":"9","author":"Carvalho","year":"2021","journal-title":"Vaccines"},{"issue":"5","key":"10.1016\/j.biopha.2023.115175_bib97","doi-asserted-by":"crossref","first-page":"97","DOI":"10.3390\/v9050097","article-title":"Historical perspectives on flavivirus research","volume":"9","author":"Holbrook","year":"2017","journal-title":"Viruses"},{"key":"10.1016\/j.biopha.2023.115175_bib98","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1146\/annurev-med-040717-051127","article-title":"Zika virus vaccine development: progress in the face of new challenges","volume":"70","author":"Diamond","year":"2019","journal-title":"Annu. Rev. Med."},{"issue":"11","key":"10.1016\/j.biopha.2023.115175_bib99","doi-asserted-by":"crossref","first-page":"6049","DOI":"10.3390\/ijerph10116049","article-title":"Flaviviruses in Europe: complex circulation patterns and their consequences for the diagnosis and control of West Nile disease","volume":"10","author":"Beck","year":"2013","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.biopha.2023.115175_bib100","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/B978-0-444-53488-0.00002-X","article-title":"Basics of virology","volume":"123","author":"Pellett","year":"2014","journal-title":"Handb. Clin. Neurol."},{"key":"10.1016\/j.biopha.2023.115175_bib101","doi-asserted-by":"crossref","first-page":"4065","DOI":"10.2147\/IDR.S347545","article-title":"Development of highly sensitive sandwich ELISA for the early-phase diagnosis of chikungunya virus Utilizing rE2-E1 protein","author":"Islamuddin","year":"2022","journal-title":"Infect. Drug Resist."},{"key":"10.1016\/j.biopha.2023.115175_bib102","article-title":"Viruses that Cause arthritis","author":"Moore","year":"2021","journal-title":"UptoDate"},{"issue":"2","key":"10.1016\/j.biopha.2023.115175_bib103","doi-asserted-by":"crossref","first-page":"354","DOI":"10.3390\/microorganisms10020354","article-title":"Spread of a novel indian ocean lineage carrying E1-K211E\/E2-V264A of chikungunya virus east\/central\/south african genotype across the Indian Subcontinent, Southeast Asia, and Eastern Africa","volume":"10","author":"Phadungsombat","year":"2022","journal-title":"Microorganisms"},{"key":"10.1016\/j.biopha.2023.115175_bib104","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1146\/annurev-immunol-031210-101315","article-title":"Immune response to dengue virus and prospects for a vaccine","volume":"29","author":"Murphy","year":"2011","journal-title":"Annu. Rev. Immunol."},{"issue":"4","key":"10.1016\/j.biopha.2023.115175_bib105","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0009337","article-title":"The worldwide seroprevalence of DENV, CHIKV and ZIKV infection: a systematic review and meta-analysis","volume":"15","author":"Li","year":"2021","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"suppl_5","key":"10.1016\/j.biopha.2023.115175_bib106","doi-asserted-by":"crossref","first-page":"S453","DOI":"10.1093\/infdis\/jiw285","article-title":"Invasiveness of Aedes aegypti and Aedes albopictus and vectorial capacity for chikungunya virus","volume":"214","author":"Lounibos","year":"2016","journal-title":"J. Infect. Dis."},{"issue":"3","key":"10.1016\/j.biopha.2023.115175_bib107","doi-asserted-by":"crossref","first-page":"249","DOI":"10.1016\/0277-9536(86)90345-X","article-title":"Aedes aegypti mosquitoes in the Americas: a review of their interactions with the human population","volume":"23","author":"Slosek","year":"1986","journal-title":"Soc. Sci. Med."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib108","doi-asserted-by":"crossref","first-page":"96","DOI":"10.3390\/ijerph15010096","article-title":"The Zika virus epidemic in Brazil: from discovery to future implications","volume":"15","author":"Lowe","year":"2018","journal-title":"Int. J. Environ. Res. Public Health"},{"issue":"4","key":"10.1016\/j.biopha.2023.115175_bib109","doi-asserted-by":"crossref","first-page":"295","DOI":"10.5958\/0975-4377.2020.00048.8","article-title":"A review on zika virus infection","volume":"12","author":"Yadav","year":"2020","journal-title":"Res. J. Pharm. Dos. Forms Technol."},{"issue":"5","key":"10.1016\/j.biopha.2023.115175_bib110","doi-asserted-by":"crossref","first-page":"841","DOI":"10.3201\/eid2305.161715","article-title":"Estimated incubation period for Zika virus disease","volume":"23","author":"Krow-Lucal","year":"2017","journal-title":"Emerg. Infect. Dis."},{"issue":"4","key":"10.1016\/j.biopha.2023.115175_bib111","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1017\/S0950268808001167","article-title":"Atypical Chikungunya virus infections: clinical manifestations, mortality and risk factors for severe disease during the 2005\u20132006 outbreak on Reunion","volume":"137","author":"Economopoulou","year":"2009","journal-title":"Epidemiol. Infect."},{"issue":"4","key":"10.1016\/j.biopha.2023.115175_bib112","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1002\/art.40384","article-title":"Frequency of chronic joint pain following chikungunya virus infection: a Colombian cohort study","volume":"70","author":"Chang","year":"2018","journal-title":"Arthritis Rheumatol."},{"key":"10.1016\/j.biopha.2023.115175_bib113","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.tmaid.2018.06.006","article-title":"Diagnosis and outcomes of pregnant women with Zika virus infection in two municipalities of Risaralda, Colombia: Second report of the ZIKERNCOL study","volume":"25","author":"Rodriguez-Morales","year":"2018","journal-title":"Travel Med. Infect. Dis."},{"key":"10.1016\/j.biopha.2023.115175_bib114","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.ijid.2020.07.033","article-title":"Dengue fever as an emerging disease in Afghanistan: epidemiology of the first reported cases","volume":"99","author":"Sahak","year":"2020","journal-title":"Int. J. Infect. Dis."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12916-014-0147-9","article-title":"Predicting outcome from dengue","volume":"12","author":"Yacoub","year":"2014","journal-title":"BMC Med."},{"key":"10.1016\/j.biopha.2023.115175_bib116","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.ijid.2016.07.017","article-title":"Zika, dengue, and chikungunya co-infection in a pregnant woman from Colombia","volume":"51","author":"Villamil-G\u00f3mez","year":"2016","journal-title":"Int. J. Infect. Dis."},{"issue":"4","key":"10.1016\/j.biopha.2023.115175_bib117","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.jcma.2016.03.001","article-title":"Why Zika virus infection has become a public health concern?","volume":"79","author":"Chen","year":"2016","journal-title":"J. Chin. Med. Assoc."},{"issue":"3","key":"10.1016\/j.biopha.2023.115175_bib118","doi-asserted-by":"crossref","first-page":"35","DOI":"10.9734\/ijpr\/2023\/v12i3229","article-title":"A review on zika virus: epidemiology, pathogenesis and clinical outcomes","volume":"12","author":"Nwalozie","year":"2023","journal-title":"Int. J. Pathog. Res."},{"issue":"50","key":"10.1016\/j.biopha.2023.115175_bib119","doi-asserted-by":"crossref","first-page":"30426","DOI":"10.2807\/1560-7917.ES.2016.21.50.30426","article-title":"Serodiagnosis of Zika virus (ZIKV) infections by a novel NS1-based ELISA devoid of cross-reactivity with dengue virus antibodies: a multicohort study of assay performance, 2015 to 2016","volume":"21","author":"Steinhagen","year":"2016","journal-title":"Eurosurveillance"},{"key":"10.1016\/j.biopha.2023.115175_bib120","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/978-3-319-59406-4_7","article-title":"Laboratory Diagnosis","author":"D\u00edaz-Men\u00e9ndez","year":"2017","journal-title":"Zika Virus Infect.: Risk Spread Eur."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib121","first-page":"1","article-title":"Zika virus genome biology and molecular pathogenesis","volume":"6","author":"Wang","year":"2017","journal-title":"Emerg. Microbes Infect."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib122","doi-asserted-by":"crossref","DOI":"10.1002\/jmv.28243","article-title":"Modulation of cellular machineries by Zika virus\u2010encoded proteins","volume":"95","author":"Dong","year":"2023","journal-title":"J. Med. Virol."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib123","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13567-021-00966-2","article-title":"Structure and function of capsid protein in flavivirus infection and its applications in the development of vaccines and therapeutics","volume":"52","author":"Zhang","year":"2021","journal-title":"Vet. Res."},{"issue":"4","key":"10.1016\/j.biopha.2023.115175_bib124","doi-asserted-by":"crossref","first-page":"91","DOI":"10.3390\/v9040091","article-title":"Dengue virus non-structural protein 5","volume":"9","author":"El Sahili","year":"2017","journal-title":"Viruses"},{"key":"10.1016\/j.biopha.2023.115175_bib125","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/j.meegid.2019.01.018","article-title":"ZIKA virus entry mechanisms in human cells","volume":"69","author":"Agrelli","year":"2019","journal-title":"Infect. Genet. Evol."},{"issue":"10","key":"10.1016\/j.biopha.2023.115175_bib126","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1080\/1061186X.2020.1792916","article-title":"Envelope proteins as antiviral drug target","volume":"28","author":"Verma","year":"2020","journal-title":"J. Drug Target."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib127","doi-asserted-by":"crossref","first-page":"e01983","DOI":"10.1128\/AAC.01983-17","article-title":"Zika virus replication is substantially inhibited by novel favipiravir and interferon alpha combination regimens","volume":"62","author":"Pires de Mello","year":"2018","journal-title":"Antimicrob. Agents Chemother."},{"key":"10.1016\/j.biopha.2023.115175_bib128","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.coviro.2016.11.007","article-title":"Flavivirus transmission focusing on Zika","volume":"22","author":"Vasilakis","year":"2017","journal-title":"Curr. Opin. Virol."},{"key":"10.1016\/j.biopha.2023.115175_bib129","unstructured":"Kegode, I.A.M., Defining the Role of Zika Virus Exonuclease Resistant RNA2 in Viral Pathogenesis. 2023, University of Colorado Denver, Anschutz Medical Campus."},{"issue":"9","key":"10.1016\/j.biopha.2023.115175_bib130","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0005024","article-title":"Vector competence of French Polynesian Aedes aegypti and Aedes polynesiensis for Zika virus","volume":"10","author":"Richard","year":"2016","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib131","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1038\/s41598-017-18682-3","article-title":"Zika virus in salivary glands of five different species of wild-caught mosquitoes from Mexico","volume":"8","author":"Elizondo-Quiroga","year":"2018","journal-title":"Sci. Rep."},{"issue":"10","key":"10.1016\/j.biopha.2023.115175_bib132","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003188","article-title":"Aedes hensilli as a potential vector of Chikungunya and Zika viruses","volume":"8","author":"Ledermann","year":"2014","journal-title":"PLoS Negl. Trop. Dis."},{"issue":"6","key":"10.1016\/j.biopha.2023.115175_bib133","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1017\/S0007485315000103","article-title":"An entomological review of invasive mosquitoes in Europe","volume":"105","author":"Medlock","year":"2015","journal-title":"Bull. \u00c8ntomol. Res."},{"key":"10.1016\/j.biopha.2023.115175_bib134","article-title":"On the seasonal occurrence and abundance of the Zika virus vector mosquito Aedes aegypti in the contiguous United States","volume":"8","author":"Monaghan","year":"2016","journal-title":"PLoS Curr."},{"key":"10.1016\/j.biopha.2023.115175_bib135","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.ijid.2016.05.014","article-title":"Zika virus, vectors, reservoirs, amplifying hosts, and their potential to spread worldwide: what we know and what we should investigate urgently","volume":"48","author":"Vorou","year":"2016","journal-title":"Int. J. Infect. Dis."},{"key":"10.1016\/j.biopha.2023.115175_bib136","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.ejogrb.2021.07.012","article-title":"Zika virus infection in pregnant women and their children: a review","volume":"265","author":"Marb\u00e1n-Castro","year":"2021","journal-title":"Eur. J. Obstet. Gynecol. Reprod. Biol."},{"issue":"4","key":"10.1016\/j.biopha.2023.115175_bib137","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.tmaid.2016.07.002","article-title":"Non-vector-borne transmission of Zika virus: a systematic review","volume":"14","author":"Grischott","year":"2016","journal-title":"Travel Med. Infect. Dis."},{"issue":"6","key":"10.1016\/j.biopha.2023.115175_bib138","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1016\/S1473-3099(16)00095-5","article-title":"Detection and sequencing of Zika virus from amniotic fluid of fetuses with microcephaly in Brazil: a case study","volume":"16","author":"Calvet","year":"2016","journal-title":"Lancet Infect. Dis."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib139","doi-asserted-by":"crossref","first-page":"68","DOI":"10.5858\/arpa.2016-0343-OA","article-title":"Autopsy and postmortem studies are concordant: pathology of Zika virus infection is neurotropic in fetuses and infants with microcephaly following transplacental transmission","volume":"141","author":"Schwartz","year":"2017","journal-title":"Arch. Pathol. Lab. Med."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib140","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tmrv.2016.08.001","article-title":"Zika virus and the blood supply: what do we know?","volume":"31","author":"Jimenez","year":"2017","journal-title":"Transfus. Med. Rev."},{"issue":"7","key":"10.1016\/j.biopha.2023.115175_bib141","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1038\/s41577-020-00474-y","article-title":"Human stem cell models to study host\u2013virus interactions in the central nervous system","volume":"21","author":"Harschnitz","year":"2021","journal-title":"Nat. Rev. Immunol."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib142","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1016\/j.yapd.2017.04.002","article-title":"Emerging infectious diseases","volume":"64","author":"Rathore","year":"2017","journal-title":"Adv. Pediatr."},{"issue":"2","key":"10.1016\/j.biopha.2023.115175_bib143","doi-asserted-by":"crossref","first-page":"377","DOI":"10.3390\/biomedicines11020377","article-title":"Mechanisms, effects, and management of neurological complications of post-acute sequelae of COVID-19 (NC-PASC)","volume":"11","author":"Ong","year":"2023","journal-title":"Biomedicines"},{"issue":"10","key":"10.1016\/j.biopha.2023.115175_bib144","doi-asserted-by":"crossref","first-page":"1837","DOI":"10.1038\/s41418-018-0163-y","article-title":"Zika virus E protein alters the properties of human fetal neural stem cells by modulating microRNA circuitry","volume":"25","author":"Bhagat","year":"2018","journal-title":"Cell Death Differ."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib145","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1038\/s41421-018-0042-1","article-title":"Disruption of glial cell development by Zika virus contributes to severe microcephalic newborn mice","volume":"4","author":"Li","year":"2018","journal-title":"Cell Discov."},{"key":"10.1016\/j.biopha.2023.115175_bib146","doi-asserted-by":"crossref","first-page":"2766","DOI":"10.3389\/fmicb.2018.02766","article-title":"Microglia increase inflammatory responses in iPSC-derived human brainspheres","volume":"9","author":"Abreu","year":"2018","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.biopha.2023.115175_bib147","doi-asserted-by":"crossref","DOI":"10.1016\/j.cyto.2019.154864","article-title":"Lineage-dependent differences of Zika virus infection in a susceptible mouse model are associated with different profiles of cytokines, chemokines, growth factors and acute phase proteins","volume":"125","author":"Dowall","year":"2020","journal-title":"Cytokine"},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib148","doi-asserted-by":"crossref","DOI":"10.1002\/rmv.2021","article-title":"Research advancements in the neurological presentation of flaviviruses","volume":"29","author":"Chen","year":"2019","journal-title":"Rev. Med. Virol."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib149","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pmed.1002203","article-title":"Zika virus infection as a cause of congenital brain abnormalities and Guillain\u2013Barr\u00e9 syndrome: systematic review","volume":"14","author":"Krauer","year":"2017","journal-title":"PLoS Med."},{"issue":"2","key":"10.1016\/j.biopha.2023.115175_bib150","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/S1734-1140(10)70261-9","article-title":"Guillain-Barr\u00e9 syndrome (GBS)","volume":"62","author":"Pithadia","year":"2010","journal-title":"Pharmacol. Rep."},{"key":"10.1016\/j.biopha.2023.115175_bib151","doi-asserted-by":"crossref","first-page":"116","DOI":"10.3389\/fnmol.2018.00116","article-title":"Autoimmune neurological conditions associated with Zika virus infection","volume":"11","author":"Acosta-Ampudia","year":"2018","journal-title":"Front. Mol. Neurosci."},{"issue":"2","key":"10.1016\/j.biopha.2023.115175_bib152","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1177\/088307380201700205","article-title":"Significance of microcephaly among children with developmental disabilities","volume":"17","author":"Watemberg","year":"2002","journal-title":"J. Child Neurol."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib153","doi-asserted-by":"crossref","first-page":"26","DOI":"10.5858\/arpa.2016-0382-RA","article-title":"Zika virus infection in pregnancy, microcephaly, and maternal and fetal health: what we think, what we know, and what we think we know","volume":"141","author":"Alvarado","year":"2017","journal-title":"Arch. Pathol. Lab. Med."},{"issue":"5","key":"10.1016\/j.biopha.2023.115175_bib154","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1016\/j.cell.2016.04.032","article-title":"Brain-region-specific organoids using mini-bioreactors for modeling ZIKV exposure","volume":"165","author":"Qian","year":"2016","journal-title":"Cell"},{"issue":"19","key":"10.1016\/j.biopha.2023.115175_bib155","doi-asserted-by":"crossref","first-page":"8721","DOI":"10.7150\/thno.41648","article-title":"Stem cell programs in cancer initiation, progression, and therapy resistance","volume":"10","author":"Huang","year":"2020","journal-title":"Theranostics"},{"key":"10.1016\/j.biopha.2023.115175_bib156","first-page":"1","article-title":"Shared molecular signatures across zika virus infection and multiple sclerosis highlight AP-1 transcription factor as a potential player in Post-ZIKV MS-like phenotypes","author":"da Silva","year":"2023","journal-title":"Mol. Neurobiol."},{"key":"10.1016\/j.biopha.2023.115175_bib157","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/j.clineuro.2018.10.007","article-title":"Acute disseminated encephalomyelitis: a rare autoimmune complication of herpes simplex encephalitis in the adult","volume":"175","author":"Bocos-Portillo","year":"2018","journal-title":"Clin. Neurol. Neurosurg."},{"issue":"9","key":"10.1016\/j.biopha.2023.115175_bib158","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1038\/sc.2015.58","article-title":"Spinal cord involvement in tuberculous meningitis","volume":"53","author":"Garg","year":"2015","journal-title":"Spinal Cord."},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib159","doi-asserted-by":"crossref","first-page":"14","DOI":"10.3390\/v12010014","article-title":"Human coronaviruses and other respiratory viruses: underestimated opportunistic pathogens of the central nervous system?","volume":"12","author":"Desforges","year":"2019","journal-title":"viruses"},{"key":"10.1016\/j.biopha.2023.115175_bib160","doi-asserted-by":"crossref","DOI":"10.1016\/j.modpat.2023.100188","article-title":"Flaviviruses & the traveler: around the world and to your stage","author":"Hale","year":"2023","journal-title":"Mod. Pathol."},{"issue":"12","key":"10.1016\/j.biopha.2023.115175_bib161","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1016\/j.vaccine.2014.01.040","article-title":"A review of successful flavivirus vaccines and the problems with those flaviviruses for which vaccines are not yet available","volume":"32","author":"Ishikawa","year":"2014","journal-title":"Vaccine"},{"issue":"11","key":"10.1016\/j.biopha.2023.115175_bib162","doi-asserted-by":"crossref","first-page":"1816","DOI":"10.3390\/vaccines10111816","article-title":"Current advances in zika vaccine development","volume":"10","author":"Wang","year":"2022","journal-title":"Vaccines"},{"key":"10.1016\/j.biopha.2023.115175_bib163","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.addr.2020.12.008","article-title":"Non-viral COVID-19 vaccine delivery systems","volume":"169","author":"Park","year":"2021","journal-title":"Adv. Drug Deliv. Rev."},{"issue":"4","key":"10.1016\/j.biopha.2023.115175_bib164","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1007\/s00203-023-03480-5","article-title":"Nucleic acid-based vaccine platforms against the coronavirus disease 19 (COVID-19)","volume":"205","author":"Baghban","year":"2023","journal-title":"Arch. Microbiol."},{"issue":"7","key":"10.1016\/j.biopha.2023.115175_bib165","doi-asserted-by":"crossref","first-page":"e211","DOI":"10.1016\/S1473-3099(18)30063-X","article-title":"Development of vaccines against Zika virus","volume":"18","author":"Poland","year":"2018","journal-title":"Lancet Infect. Dis."},{"issue":"6","key":"10.1016\/j.biopha.2023.115175_bib166","doi-asserted-by":"crossref","first-page":"1485","DOI":"10.1016\/j.celrep.2016.07.049","article-title":"Broadly neutralizing activity of Zika virus-immune sera identifies a single viral serotype","volume":"16","author":"Dowd","year":"2016","journal-title":"Cell Rep."},{"key":"10.1016\/j.biopha.2023.115175_bib167","series-title":"Infections and Pregnancy","first-page":"247","article-title":"Zika, lyme, and chagas disease","author":"Rashmi","year":"2022"},{"issue":"7","key":"10.1016\/j.biopha.2023.115175_bib168","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.3390\/v13071307","article-title":"Antivirals against the Chikungunya virus","volume":"13","author":"Battisti","year":"2021","journal-title":"Viruses"},{"key":"10.1016\/j.biopha.2023.115175_bib169","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.antiviral.2016.03.010","article-title":"Zika virus: History, emergence, biology, and prospects for control","volume":"130","author":"Weaver","year":"2016","journal-title":"Antivir. Res."},{"issue":"8","key":"10.1016\/j.biopha.2023.115175_bib170","doi-asserted-by":"crossref","first-page":"1042","DOI":"10.1049\/iet-nbt.2018.5083","article-title":"Green synthesis of copper oxide nanoparticles and mosquito larvicidal activity against dengue, zika and chikungunya causing vector Aedes aegypti","volume":"12","author":"Muthamil Selvan","year":"2018","journal-title":"IET Nanobiotechnol."},{"issue":"5","key":"10.1016\/j.biopha.2023.115175_bib171","doi-asserted-by":"crossref","DOI":"10.1503\/cmaj.151486","article-title":"Zika virus infection","volume":"188","author":"MacFadden","year":"2016","journal-title":"CMAJ"},{"issue":"1","key":"10.1016\/j.biopha.2023.115175_bib172","doi-asserted-by":"crossref","first-page":"31","DOI":"10.5603\/IMH.2016.0007","article-title":"Zika\u2014another threat on the epidemiological map of the world","volume":"67","author":"Korzeniewski","year":"2016","journal-title":"Int. Marit. Health"},{"key":"10.1016\/j.biopha.2023.115175_bib173","doi-asserted-by":"crossref","first-page":"110","DOI":"10.3389\/fmicb.2017.00110","article-title":"Zika virus: transmission, detection, control, and prevention","volume":"8","author":"Sharma","year":"2017","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.biopha.2023.115175_bib174","unstructured":"Focks, D.A., A review of entomological sampling methods and indicators for dengue vectors. 2004."},{"issue":"11","key":"10.1016\/j.biopha.2023.115175_bib175","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1002\/ps.4044","article-title":"Control methods against invasive Aedes mosquitoes in Europe: a review","volume":"71","author":"Baldacchino","year":"2015","journal-title":"Pest Manag. Sci."},{"issue":"8","key":"10.1016\/j.biopha.2023.115175_bib176","doi-asserted-by":"crossref","first-page":"508","DOI":"10.1038\/s41579-018-0025-0","article-title":"Controlling vector-borne diseases by releasing modified mosquitoes","volume":"16","author":"Flores","year":"2018","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.biopha.2023.115175_bib177","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.ibmb.2017.11.008","article-title":"Upregulation of Aedes aegypti Vago1 by Wolbachia and its effect on dengue virus replication","volume":"92","author":"Asad","year":"2018","journal-title":"Insect Biochem. Mol. Biol."},{"issue":"4","key":"10.1016\/j.biopha.2023.115175_bib178","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1005536","article-title":"Wolbachia blocks viral genome replication early in infection without a transcriptional response by the endosymbiont or host small RNA pathways","volume":"12","author":"Rainey","year":"2016","journal-title":"PLoS Pathog."}],"container-title":["Biomedicine & Pharmacotherapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332223009666?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0753332223009666?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T07:41:40Z","timestamp":1777880500000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0753332223009666"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,9]]},"references-count":178,"alternative-id":["S0753332223009666"],"URL":"https:\/\/doi.org\/10.1016\/j.biopha.2023.115175","relation":{},"ISSN":["0753-3322"],"issn-type":[{"value":"0753-3322","type":"print"}],"subject":[],"published":{"date-parts":[[2023,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Insights into the structure, functional perspective, and pathogenesis of ZIKV: an updated review","name":"articletitle","label":"Article Title"},{"value":"Biomedicine & Pharmacotherapy","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopha.2023.115175","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier Masson SAS.","name":"copyright","label":"Copyright"}],"article-number":"115175"}}