{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T12:16:42Z","timestamp":1791202602232,"version":"4.2.0"},"reference-count":48,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2005,9,1]],"date-time":"2005-09-01T00:00:00Z","timestamp":1125532800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biological Psychiatry"],"published-print":{"date-parts":[[2005,9]]},"DOI":"10.1016\/j.biopsych.2005.04.035","type":"journal-article","created":{"date-parts":[[2005,7,6]],"date-time":"2005-07-06T21:13:22Z","timestamp":1120684402000},"page":"495-503","source":"Crossref","is-referenced-by-count":188,"title":["A Double Dissociation of Ventromedial Prefrontal Cortical Responses to Sad and Happy Stimuli in Depressed and Healthy Individuals"],"prefix":"10.1016","volume":"58","author":[{"given":"Paul A.","family":"Keedwell","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Andrew","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven C.R.","family":"Williams","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mick J.","family":"Brammer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mary L.","family":"Phillips","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopsych.2005.04.035_bib1","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1093\/cercor\/10.3.295","article-title":"Emotion, decision making and the orbitofrontal cortex","volume":"10","author":"Bechara","year":"2000","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.biopsych.2005.04.035_bib2","series-title":"Depression","author":"Beck","year":"1967"},{"key":"10.1016\/j.biopsych.2005.04.035_bib3","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1001\/archpsyc.1961.01710120031004","article-title":"An inventory for measuring depression","volume":"4","author":"Beck","year":"1961","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.biopsych.2005.04.035_bib4","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1016\/S0730-725X(97)00135-5","article-title":"Generic brain activation mapping in functional magnetic resonance imaging","volume":"15","author":"Brammer","year":"1997","journal-title":"Magn Reson Imaging"},{"key":"10.1016\/j.biopsych.2005.04.035_bib5","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0167-2789(03)00136-2","article-title":"Construction of multivariate surrogate sets from nonlinear data using the wavelet transform","volume":"182","author":"Breakspear","year":"2003","journal-title":"Physica D"},{"key":"10.1016\/j.biopsych.2005.04.035_bib6","series-title":"The Social Origins of Depression","author":"Brown","year":"1978"},{"key":"10.1016\/j.biopsych.2005.04.035_bib7","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1002\/1097-0193(200102)12:2<61::AID-HBM1004>3.0.CO;2-W","article-title":"Coloured noise and computational inference in neurophysiological (fMRI) time series analysis","volume":"12","author":"Bullmore","year":"2001","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.biopsych.2005.04.035_bib8","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1109\/42.750253","article-title":"Global, voxel and cluster tests, by theory and permutation, for a difference between two groups of structural MR images of the brain","volume":"18","author":"Bullmore","year":"1999","journal-title":"IEEE Trans Med Imaging"},{"key":"10.1016\/j.biopsych.2005.04.035_bib9","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1016\/S1364-6613(00)01483-2","article-title":"Cognitive and emotional influences in anterior cingulate cortex","volume":"4","author":"Bush","year":"2000","journal-title":"Trends Cogn Sci"},{"key":"10.1016\/j.biopsych.2005.04.035_bib10","series-title":"On the Self-Regulation of Behaviour","author":"Carver","year":"1998"},{"issue":"2","key":"10.1016\/j.biopsych.2005.04.035_bib11","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1037\/0021-843X.91.2.87","article-title":"Diurnal variation in clinical depression and accessibility of memories of positive and negative experiences","volume":"91","author":"Clark","year":"1982","journal-title":"J Abnorm Psychol"},{"key":"10.1016\/j.biopsych.2005.04.035_bib12","doi-asserted-by":"crossref","first-page":"3033","DOI":"10.1523\/JNEUROSCI.20-08-03033.2000","article-title":"Neural activity relating to generation and representation of galvanic skin conductance responses","volume":"20","author":"Critchley","year":"2000","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2005.04.035_bib13","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/S0006-3223(00)01020-9","article-title":"Neuroimaging studies of mood disorders","volume":"48","author":"Drevets","year":"2000","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2005.04.035_bib14","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/S0006-3223(01)01244-6","article-title":"Principal components of the Beck Depression Inventory and regional cerebral metabolism in unipolar and bipolar depression","volume":"51","author":"Dunn","year":"2002","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2005.04.035_bib15","series-title":"Pictures of Facial Affect","author":"Ekman","year":"1976"},{"issue":"16","key":"10.1016\/j.biopsych.2005.04.035_bib16","doi-asserted-by":"crossref","first-page":"6159","DOI":"10.1523\/JNEUROSCI.20-16-06159.2000","article-title":"Dissociable neural responses in human reward systems","volume":"20","author":"Elliott","year":"2000","journal-title":"J Neurosci"},{"issue":"3","key":"10.1016\/j.biopsych.2005.04.035_bib17","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1016\/j.neuroimage.2003.10.010","article-title":"Instrumental responding for rewards is associated with enhanced neuronal response in subcortical reward systems","volume":"21","author":"Elliott","year":"2004","journal-title":"Neuroimage"},{"key":"10.1016\/j.biopsych.2005.04.035_bib18","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1001\/archpsyc.59.7.597","article-title":"The neural basis of mood-congruent processing biases in depression","volume":"59","author":"Elliott","year":"2002","journal-title":"Arch Gen Psychiatry"},{"issue":"1","key":"10.1016\/j.biopsych.2005.04.035_bib19","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/S0925-4927(01)00110-X","article-title":"Time course of the subjective emotional response to aversive pictures","volume":"108","author":"Garrett","year":"2001","journal-title":"Psychiatry Res Neuroimaging"},{"key":"10.1016\/j.biopsych.2005.04.035_bib20","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1176\/ajp.152.3.341","article-title":"Brain activity during transient sadness and happiness in healthy women","volume":"152","author":"George","year":"1995","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.biopsych.2005.04.035_bib21","series-title":"Treatment of Recurrent Depression","first-page":"103","article-title":"New depression treatment strategies","author":"George","year":"2001"},{"key":"10.1016\/j.biopsych.2005.04.035_bib22","series-title":"The Detection of Psychiatric Illness by Questionnaire [Maudsley Monograph No. 21]","author":"Goldberg","year":"1972"},{"key":"10.1016\/j.biopsych.2005.04.035_bib23","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1177\/026988119901300202","article-title":"Comparison of buspirone with diazepam and fluvoxamine on aversive classical conditioning in humans","volume":"13","author":"Hellewell","year":"1999","journal-title":"J Psychopharmacol"},{"key":"10.1016\/j.biopsych.2005.04.035_bib23a","doi-asserted-by":"crossref","DOI":"10.1080\/02699930050117684","article-title":"Decreased responsiveness to reward in depression. Cognition and emotion","volume":"14","author":"Henriques","year":"2000","journal-title":"Cognit Emot"},{"key":"10.1016\/j.biopsych.2005.04.035_bib24","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1162\/089892900564055","article-title":"The representation of objects in the human occipital and temporal cortex","volume":"12","author":"Ishai","year":"2000","journal-title":"J Cogn Neurosci"},{"issue":"17","key":"10.1016\/j.biopsych.2005.04.035_bib25","doi-asserted-by":"crossref","first-page":"3683","DOI":"10.1097\/00001756-200112040-00016","article-title":"Dissociation of reward anticipation and outcome with event-related fMRI","volume":"12","author":"Knutson","year":"2001","journal-title":"Neuroreport"},{"key":"10.1016\/j.biopsych.2005.04.035_bib26","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1016\/S0006-3223(02)01785-7","article-title":"Neural abnormalities during cognitive generation of affect in treatment-resistant depression","volume":"54","author":"Kumari","year":"2003","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2005.04.035_bib27","series-title":"International Affective Picture System (IAPS)","author":"Lang","year":"1997"},{"key":"10.1016\/j.biopsych.2005.04.035_bib28","doi-asserted-by":"crossref","first-page":"1830","DOI":"10.1176\/appi.ajp.159.11.1830","article-title":"Unmasking disease-specific cerebral blood flow abnormalities","volume":"159","author":"Liotti","year":"2002","journal-title":"Am J Psychiatry"},{"issue":"2","key":"10.1016\/j.biopsych.2005.04.035_bib29","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1017\/S0033291700056440","article-title":"Effect of depression on the speed of recall of pleasant and unpleasant experiences","volume":"5","author":"Lloyd","year":"1975","journal-title":"Psychol Med"},{"key":"10.1016\/j.biopsych.2005.04.035_bib30","series-title":"Brain Mapping","first-page":"458","article-title":"Depression","author":"Mayberg","year":"2000"},{"key":"10.1016\/j.biopsych.2005.04.035_bib31","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1016\/S0006-3223(00)01036-2","article-title":"Regional metabolic effects of fluoxetine in major depression","volume":"48","author":"Mayberg","year":"2000","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2005.04.035_bib32","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1176\/ajp.156.5.675","article-title":"Reciprocal limbic-cortical function and negative mood","volume":"156","author":"Mayberg","year":"1999","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.biopsych.2005.04.035_bib33","doi-asserted-by":"crossref","first-page":"651","DOI":"10.1016\/j.neuron.2005.02.014","article-title":"Deep brain stimulation for treatment-resistant depression","volume":"45","author":"Mayberg","year":"2005","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2005.04.035_bib34","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1192\/bjp.137.1.93","article-title":"Electrodermal activity in depression","volume":"137","author":"Mirkin","year":"1993","journal-title":"Br J Psychiatry"},{"key":"10.1016\/j.biopsych.2005.04.035_bib35","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1097\/00001756-200302100-00003","article-title":"Neural response to pleasant stimuli in anhedonia","volume":"14","author":"Mitterschiffthaler","year":"2003","journal-title":"Neuroreport"},{"key":"10.1016\/j.biopsych.2005.04.035_bib36","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1093\/cercor\/10.1.93","article-title":"Functional dissociation between medial and lateral prefrontal cortical spatiotemporal activation in negative and positive emotions","volume":"10","author":"Northoff","year":"2000","journal-title":"Cereb Cortex"},{"issue":"1","key":"10.1016\/j.biopsych.2005.04.035_bib37","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1038\/82959","article-title":"Abstract reward and punishment representations in the human orbitofrontal cortex","volume":"4","author":"O\u2019Doherty","year":"2001","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.biopsych.2005.04.035_bib38","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1093\/cercor\/10.3.206","article-title":"The organisation of networks within the orbital and medial prefrontal cortex of rats, monkeys and humans","volume":"10","author":"Ongur","year":"2000","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.biopsych.2005.04.035_bib39","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1176\/ajp.150.5.713","article-title":"Neural correlates of self-induced dysphoria","volume":"150","author":"Pardo","year":"1993","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.biopsych.2005.04.035_bib40","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1006\/nimg.2002.1087","article-title":"Functional neuroanatomy of emotion","volume":"16","author":"Phan","year":"2001","journal-title":"Neuroimage"},{"key":"10.1016\/j.biopsych.2005.04.035_bib41","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1016\/S0006-3223(03)00168-9","article-title":"Neurobiology of emotion perception I","volume":"54","author":"Phillips","year":"2003","journal-title":"Biol Psychiatry"},{"issue":"suppl 16","key":"10.1016\/j.biopsych.2005.04.035_bib42","first-page":"1","article-title":"The definition and meaning of treatment resistant depression","volume":"62","author":"Sackheim","year":"2001","journal-title":"J Clin Psychiatry"},{"issue":"2\u20133","key":"10.1016\/j.biopsych.2005.04.035_bib43","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/S0925-4927(97)00063-2","article-title":"Functional MRI reveals left amygdala activation during emotion","volume":"76","author":"Schneider","year":"1997","journal-title":"Psychiatry Res"},{"issue":"4","key":"10.1016\/j.biopsych.2005.04.035_bib44","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1016\/S0896-6273(03)00467-7","article-title":"Dissociation of neural representation of intensity and affective valuation in human gustation","volume":"39","author":"Small","year":"2003","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2005.04.035_bib45","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1016\/j.biopsych.2004.10.028","article-title":"A differential pattern of neural response toward sad versus happy facial expressions in major depressive disorder","volume":"57","author":"Surguladze","year":"2005","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2005.04.035_bib46","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1192\/apt.9.6.446","article-title":"Neural systems underlying affective disorders","volume":"9","author":"Surguladze","year":"2003","journal-title":"Adv Psychiatr Treat"},{"key":"10.1016\/j.biopsych.2005.04.035_bib47","series-title":"Co-planar Stereotactic Atlas of the Human Brain","author":"Talairach","year":"1998"}],"container-title":["Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322305004968?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322305004968?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,3]],"date-time":"2023-05-03T18:01:11Z","timestamp":1683136871000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006322305004968"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,9]]},"references-count":48,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,9]]}},"alternative-id":["S0006322305004968"],"URL":"https:\/\/doi.org\/10.1016\/j.biopsych.2005.04.035","relation":{},"ISSN":["0006-3223"],"issn-type":[{"value":"0006-3223","type":"print"}],"subject":[],"published":{"date-parts":[[2005,9]]}}}