{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T18:50:34Z","timestamp":1790967034873,"version":"4.1.0"},"reference-count":28,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2009,3,1]],"date-time":"2009-03-01T00:00:00Z","timestamp":1235865600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biological Psychiatry"],"published-print":{"date-parts":[[2009,3]]},"DOI":"10.1016\/j.biopsych.2008.10.026","type":"journal-article","created":{"date-parts":[[2008,11,29]],"date-time":"2008-11-29T10:16:03Z","timestamp":1227953763000},"page":"541-545","source":"Crossref","is-referenced-by-count":40,"title":["Expression of RGS4 Splice Variants in Dorsolateral Prefrontal Cortex of Schizophrenic and Bipolar Disorder Patients"],"prefix":"10.1016","volume":"65","author":[{"given":"Lan","family":"Ding","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashok N.","family":"Hegde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopsych.2008.10.026_bib1","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1038\/sj.mp.4000866","article-title":"Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia","volume":"6","author":"Mirnics","year":"2001","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.biopsych.2008.10.026_bib2","doi-asserted-by":"crossref","first-page":"1373","DOI":"10.1093\/hmg\/11.12.1373","article-title":"Association and linkage analyses of RGS4 polymorphisms in schizophrenia","volume":"11","author":"Chowdari","year":"2002","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.biopsych.2008.10.026_bib3","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1002\/ajmg.b.30078","article-title":"Regulator of G-protein signaling 4 (RGS4) gene is associated with schizophrenia in Irish high density families","volume":"129","author":"Chen","year":"2004","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"10.1016\/j.biopsych.2008.10.026_bib4","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1002\/ajmg.b.20109","article-title":"Confirming RGS4 as a susceptibility gene for schizophrenia","volume":"125","author":"Morris","year":"2004","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"10.1016\/j.biopsych.2008.10.026_bib5","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/j.schres.2006.09.015","article-title":"RGS4 is not a susceptibility gene for schizophrenia in Japanese: Association study in a large case-control population","volume":"89","author":"Ishiguro","year":"2007","journal-title":"Schizophr Res"},{"key":"10.1016\/j.biopsych.2008.10.026_bib6","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1111\/j.1601-183x.2004.00096.x","article-title":"Association and linkage analysis of RGS4 polymorphisms with schizophrenia and bipolar disorder in Brazil","volume":"4","author":"Cordeiro","year":"2005","journal-title":"Genes Brain Behav"},{"key":"10.1016\/j.biopsych.2008.10.026_bib7","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.gene.2007.07.002","article-title":"Full length cloning and expression analysis of splice variants of regulator of G-protein signaling RGS4 in human and murine brain","volume":"401","author":"Ding","year":"2007","journal-title":"Gene"},{"key":"10.1016\/j.biopsych.2008.10.026_bib8","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/j.cell.2006.06.023","article-title":"Alternative splicing: New insights from global analyses","volume":"126","author":"Blencowe","year":"2006","journal-title":"Cell"},{"key":"10.1016\/j.biopsych.2008.10.026_bib9","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/sj.mp.4001558","article-title":"Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence","volume":"10","author":"Harrison","year":"2005","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.biopsych.2008.10.026_bib10","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/j.psc.2005.01.006","article-title":"Magnetic resonance findings in bipolar disorder","volume":"28","author":"Brambilla","year":"2005","journal-title":"Psychiatr Clin North Am"},{"key":"10.1016\/j.biopsych.2008.10.026_bib11","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0920-9964(99)00192-9","article-title":"The stanley foundation brain collection and neuropathology consortium","volume":"44","author":"Torrey","year":"2000","journal-title":"Schizophr Res"},{"key":"10.1016\/j.biopsych.2008.10.026_bib12","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/j.biopsych.2004.06.022","article-title":"Abnormalities in the dopamine system in schizophrenia may lie in altered levels of dopamine receptor-interacting proteins","volume":"56","author":"Bai","year":"2004","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2008.10.026_bib13","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1038\/sj.mp.4001434","article-title":"Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia","volume":"9","author":"Hashimoto","year":"2004","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.biopsych.2008.10.026_bib14","doi-asserted-by":"crossref","first-page":"4680","DOI":"10.1073\/pnas.032069099","article-title":"Gene expression analysis in schizophrenia: reproducible up-regulation of several members of the apolipoprotein L family located in a high-susceptibility locus for schizophrenia on chromosome 22","volume":"99","author":"Mimmack","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biopsych.2008.10.026_bib15","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S1567-133X(01)00003-5","article-title":"Reduced neuropeptide Y mRNA levels in the frontal cortex of people with schizophrenia and bipolar disorder","volume":"1","author":"Kuromitsu","year":"2001","journal-title":"Brain Res Gene Expr Patterns"},{"key":"10.1016\/j.biopsych.2008.10.026_bib16","doi-asserted-by":"crossref","first-page":"10824","DOI":"10.1074\/jbc.M108754200","article-title":"Overexpression of an alpha 1H (Cav3.2) T-type calcium channel during neuroendocrine differentiation of human prostate cancer cells","volume":"277","author":"Mariot","year":"2002","journal-title":"J Biol Chem"},{"key":"10.1016\/j.biopsych.2008.10.026_bib17","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/meth.2001.1262","article-title":"Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method","volume":"25","author":"Livak","year":"2001","journal-title":"Methods"},{"key":"10.1016\/j.biopsych.2008.10.026_bib18","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.bbaexp.2005.08.011","article-title":"A new alternative splice variant of BRCA1 containing an additional in-frame exon","volume":"1731","author":"Fortin","year":"2005","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.biopsych.2008.10.026_bib19","doi-asserted-by":"crossref","first-page":"785","DOI":"10.2144\/05385MT01","article-title":"Validation of oligonucleotide microarray data using microfluidic low-density arrays: A new statistical method to normalize real-time RT-PCR data","volume":"38","author":"Abruzzo","year":"2005","journal-title":"Biotechniques"},{"key":"10.1016\/j.biopsych.2008.10.026_bib20","doi-asserted-by":"crossref","first-page":"2804","DOI":"10.1093\/hmg\/ddl222","article-title":"RGS4 mRNA expression in postmortem human cortex is associated with COMT Val158Met genotype and COMT enzyme activity","volume":"15","author":"Lipska","year":"2006","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.biopsych.2008.10.026_bib21","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1016\/S0022-3999(02)00426-9","article-title":"Signaling networks in the pathophysiology and treatment of mood disorders","volume":"53","author":"Gould","year":"2002","journal-title":"J Psychosom Res"},{"key":"10.1016\/j.biopsych.2008.10.026_bib22","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/sj.mp.4001562","article-title":"Genetic polymorphisms of the RGS4 and dorsolateral prefrontal cortex morphometry among first episode schizophrenia patients","volume":"10","author":"Prasad","year":"2005","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.biopsych.2008.10.026_bib23","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1523\/JNEUROSCI.5112-06.2007","article-title":"Allelic variation in RGS4 impacts functional and structural connectivity in the human brain","volume":"27","author":"Buckholtz","year":"2007","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2008.10.026_bib24","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.biopsych.2005.07.041","article-title":"A polymorphism in the PDLIM5 gene associated with gene expression and schizophrenia","volume":"59","author":"Horiuchi","year":"2006","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2008.10.026_bib25","doi-asserted-by":"crossref","first-page":"1606","DOI":"10.1111\/j.1471-4159.2006.03669.x","article-title":"Acute amphetamine down-regulates RGS4 mRNA and protein expression in rat forebrain: Distinct roles of D1 and D2 dopamine receptors","volume":"96","author":"Schwendt","year":"2006","journal-title":"J Neurochem"},{"key":"10.1016\/j.biopsych.2008.10.026_bib26","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1006\/bbrc.1997.8056","article-title":"Regulation of RGS mRNAs by cAMP in PC12 cells","volume":"243","author":"Pepperl","year":"1998","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.biopsych.2008.10.026_bib27","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1136\/bmj.330.7484.158","article-title":"Schizophrenia: A genetic disorder of the synapse?","volume":"330","author":"Owen","year":"2005","journal-title":"BMJ"},{"key":"10.1016\/j.biopsych.2008.10.026_bib28","article-title":"Rgs4, calcium channels, and synaptic transmission: Implications for schizophrenia","volume":"30","author":"Hegde","year":"2004","journal-title":"Soc Neurosci Abstr"}],"container-title":["Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322308013139?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322308013139?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,24]],"date-time":"2018-12-24T02:54:00Z","timestamp":1545620040000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006322308013139"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2009,3]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2009,3]]}},"alternative-id":["S0006322308013139"],"URL":"https:\/\/doi.org\/10.1016\/j.biopsych.2008.10.026","relation":{},"ISSN":["0006-3223"],"issn-type":[{"value":"0006-3223","type":"print"}],"subject":[],"published":{"date-parts":[[2009,3]]}}}