{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T21:07:28Z","timestamp":1793394448410,"version":"4.5.0"},"reference-count":80,"publisher":"Elsevier BV","issue":"7","license":[{"start":{"date-parts":[[2012,4,1]],"date-time":"2012-04-01T00:00:00Z","timestamp":1333238400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100000025","name":"National Institute of Mental Health","doi-asserted-by":"crossref","award":["MH090386"],"award-info":[{"award-number":["MH090386"]}],"id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biological Psychiatry"],"published-print":{"date-parts":[[2012,4]]},"DOI":"10.1016\/j.biopsych.2011.11.023","type":"journal-article","created":{"date-parts":[[2012,1,6]],"date-time":"2012-01-06T01:23:29Z","timestamp":1325813009000},"page":"633-641","source":"Crossref","is-referenced-by-count":60,"title":["Comparison of the Effects of Estradiol and Progesterone on Serotonergic Function"],"prefix":"10.1016","volume":"71","author":[{"given":"Saloua","family":"Benmansour","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rami S.","family":"Weaver","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda K.","family":"Barton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Opeyemi S.","family":"Adeniji","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan","family":"Frazer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopsych.2011.11.023_bib1","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1037\/0033-295X.115.2.291","article-title":"The ABCs of depression: Integrating affective, biological, and cognitive models to explain the emergence of the gender difference in depression","volume":"115","author":"Hyde","year":"2008","journal-title":"Psychol Rev"},{"key":"10.1016\/j.biopsych.2011.11.023_bib2","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1016\/0002-9378(95)90297-X","article-title":"Hormones and depression: What are the facts about premenstrual syndrome, menopause, and hormone replacement therapy?","volume":"173","author":"Pearlstein","year":"1995","journal-title":"Am J Obstet Gynecol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib3","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1016\/j.maturitas.2006.09.006","article-title":"Sexual and psychological symptoms in the climacteric years","volume":"56","author":"Amore","year":"2007","journal-title":"Maturitas"},{"key":"10.1016\/j.biopsych.2011.11.023_bib4","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1097\/gme.0b013e31816381e9","article-title":"Depression during the menopausal transition: Window of vulnerability or continuum of risk?","volume":"15","author":"Soares","year":"2008","journal-title":"Menopause"},{"key":"10.1016\/j.biopsych.2011.11.023_bib5","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1258\/mi.2008.008019","article-title":"Depression during menopausal transition: A review of treatment strategies and pathophysiological correlates","volume":"14","author":"Frey","year":"2008","journal-title":"Menopause Int"},{"key":"10.1016\/j.biopsych.2011.11.023_bib6","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.biopsych.2003.08.011","article-title":"Lack of efficacy of estradiol for depression in postmenopausal women: A randomized, controlled trial","volume":"55","author":"Morrison","year":"2004","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2011.11.023_bib7","doi-asserted-by":"crossref","first-page":"1737","DOI":"10.2174\/092986708784872357","article-title":"Recent developments in the design of anti-depressive therapies: Targeting the serotonin transporter","volume":"15","author":"Butler","year":"2008","journal-title":"Curr Med Chem"},{"key":"10.1016\/j.biopsych.2011.11.023_bib8","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1038\/npp.2008.23","article-title":"Impact of ovarian hormones on the modulation of the serotonin transporter by fluvoxamine","volume":"34","author":"Benmansour","year":"2009","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.biopsych.2011.11.023_bib9","first-page":"327","article-title":"Behavioral despair in mice: A primary screening test for antidepressants","volume":"229","author":"Porsolt","year":"1977","journal-title":"Arch Int Pharmacodyn Ther"},{"key":"10.1016\/j.biopsych.2011.11.023_bib10","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/S0165-6147(02)02017-5","article-title":"Assessing antidepressant activity in rodents: Recent developments and future needs","volume":"23","author":"Cryan","year":"2002","journal-title":"Trends Pharmacol Sci"},{"key":"10.1016\/j.biopsych.2011.11.023_bib11","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1038\/sj.npp.1300097","article-title":"Antidepressant-like effect of different estrogenic compounds in the forced swimming test","volume":"28","author":"Estrada-Camarena","year":"2003","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.biopsych.2011.11.023_bib12","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1007\/s00213-004-2078-1","article-title":"17 Beta-estradiol-induced antidepressant-like effect in the forced swim test is absent in estrogen receptor-beta knockout (BERKO) mice","volume":"179","author":"Rocha","year":"2005","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.biopsych.2011.11.023_bib13","doi-asserted-by":"crossref","first-page":"479","DOI":"10.1016\/S0306-4530(01)00007-5","article-title":"Antidepressant-like actions of pregnancy, and progesterone in Wistar rats forced to swim","volume":"26","author":"Molina-Hernandez","year":"2001","journal-title":"Psychoneuroendocrinology"},{"key":"10.1016\/j.biopsych.2011.11.023_bib14","doi-asserted-by":"crossref","first-page":"5925","DOI":"10.1073\/pnas.93.12.5925","article-title":"Cloning of a novel receptor expressed in rat prostate and ovary","volume":"93","author":"Kuiper","year":"1996","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biopsych.2011.11.023_bib15","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/0022-4731(86)90035-X","article-title":"Cloning of the human oestrogen receptor cDNA","volume":"24","author":"Green","year":"1986","journal-title":"J Steroid Biochem"},{"key":"10.1016\/j.biopsych.2011.11.023_bib16","doi-asserted-by":"crossref","first-page":"607","DOI":"10.1006\/geno.1997.4972","article-title":"Identification of a gene (GPR30) with homology to the G-protein-coupled receptor superfamily associated with estrogen receptor expression in breast cancer","volume":"45","author":"Carmeci","year":"1997","journal-title":"Genomics"},{"key":"10.1016\/j.biopsych.2011.11.023_bib17","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.mce.2006.12.010","article-title":"GPR30: A G protein-coupled receptor for estrogen","volume":"265\u2013266","author":"Prossnitz","year":"2007","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib18","doi-asserted-by":"crossref","first-page":"904","DOI":"10.1016\/j.bbrc.2006.05.191","article-title":"G protein-coupled receptor 30 is an estrogen receptor in the plasma membrane","volume":"346","author":"Funakoshi","year":"2006","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.biopsych.2011.11.023_bib19","doi-asserted-by":"crossref","first-page":"624","DOI":"10.1210\/en.2004-1064","article-title":"Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells","volume":"146","author":"Thomas","year":"2005","journal-title":"Endocrinology"},{"key":"10.1016\/j.biopsych.2011.11.023_bib20","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1016\/S0022-3565(24)37676-1","article-title":"In vivo chronoamperometric measures of extracellular serotonin clearance in rat dorsal hippocampus: Contribution of serotonin and norepinephrine transporters","volume":"286","author":"Daws","year":"1998","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.biopsych.2011.11.023_bib21","first-page":"196","article-title":"Implications of adult hippocampal neurogenesis in antidepressant action","volume":"29","author":"Malberg","year":"2004","journal-title":"J Psychiatry Neurosci"},{"key":"10.1016\/j.biopsych.2011.11.023_bib22","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.yfrne.2007.08.006","article-title":"Uncovering the mechanisms of estrogen effects on hippocampal function","volume":"29","author":"Spencer","year":"2008","journal-title":"Front Neuroendocrinol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib23","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1007\/s002130051156","article-title":"Serotonergic mediation of the effects of fluoxetine, but not desipramine, in the rat forced swimming test","volume":"147","author":"Page","year":"1999","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.biopsych.2011.11.023_bib24","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/S0014-2999(01)01628-4","article-title":"Noradrenergic lesions differentially alter the antidepressant-like effects of reboxetine in a modified forced swim test","volume":"436","author":"Cryan","year":"2002","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib25","doi-asserted-by":"crossref","first-page":"10494","DOI":"10.1523\/JNEUROSCI.19-23-10494.1999","article-title":"Effects of chronic antidepressant treatments on serotonin transporter function, density, and mRNA level","volume":"19","author":"Benmansour","year":"1999","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2011.11.023_bib26","doi-asserted-by":"crossref","first-page":"6766","DOI":"10.1523\/JNEUROSCI.22-15-06766.2002","article-title":"Serotonin clearance in vivo is altered to a greater extent by antidepressant-induced downregulation of the serotonin transporter than by acute blockade of this transporter","volume":"22","author":"Benmansour","year":"2002","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2011.11.023_bib27","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.ejphar.2008.03.048","article-title":"Influence of brain-derived neurotrophic factor (BDNF) on serotonin neurotransmission in the hippocampus of adult rodents","volume":"587","author":"Benmansour","year":"2008","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib28","series-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","year":"1986"},{"key":"10.1016\/j.biopsych.2011.11.023_bib29","doi-asserted-by":"crossref","first-page":"1448","DOI":"10.1523\/JNEUROSCI.3777-05.2006","article-title":"The androgen 5alpha-dihydrotestosterone and its metabolite 5alpha-androstan-3beta, 17beta-diol inhibit the hypothalamo-pituitary-adrenal response to stress by acting through estrogen receptor beta-expressing neurons in the hypothalamus","volume":"26","author":"Lund","year":"2006","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2011.11.023_bib30","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.prostaglandins.2009.05.001","article-title":"Signaling, physiological functions and clinical relevance of the G protein-coupled estrogen receptor GPER","volume":"89","author":"Prossnitz","year":"2009","journal-title":"Prostaglandins Other Lipid Mediat"},{"key":"10.1016\/j.biopsych.2011.11.023_bib31","doi-asserted-by":"crossref","first-page":"239","DOI":"10.1159\/000070279","article-title":"The effect of estradiol in the striatum is blocked by ICI 182,780 but not tamoxifen: Pharmacological and behavioral evidence","volume":"77","author":"Xiao","year":"2003","journal-title":"Neuroendocrinology"},{"key":"10.1016\/j.biopsych.2011.11.023_bib32","doi-asserted-by":"crossref","first-page":"4934","DOI":"10.1021\/jm000170m","article-title":"Pyrazole ligands: Structure-affinity\/activity relationships and estrogen receptor-alpha-selective agonists","volume":"43","author":"Stauffer","year":"2000","journal-title":"J Med Chem"},{"key":"10.1016\/j.biopsych.2011.11.023_bib33","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1210\/endo.140.2.6480","article-title":"Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-beta","volume":"140","author":"Sun","year":"1999","journal-title":"Endocrinology"},{"key":"10.1016\/j.biopsych.2011.11.023_bib34","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1038\/nchembio775","article-title":"Virtual and biomolecular screening converge on a selective agonist for GPR30","volume":"2","author":"Bologa","year":"2006","journal-title":"Nat Chem Biol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib35","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S0889-8529(18)30248-2","article-title":"The steroid hormone antagonist RU486","volume":"20","author":"Baulieu","year":"1991","journal-title":"Endocrinol Metab Clin North Am"},{"key":"10.1016\/j.biopsych.2011.11.023_bib36","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/S0149-7634(98)00029-3","article-title":"Ethopharmacology of imipramine in the forced-swimming test: Gender differences","volume":"23","author":"Barros","year":"1998","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.biopsych.2011.11.023_bib37","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0091-3057(00)00392-0","article-title":"Estrous cycle and sex differences in performance on anxiety tasks coincide with increases in hippocampal progesterone and 3alpha,5alpha-THP","volume":"67","author":"Frye","year":"2000","journal-title":"Pharmacol Biochem Behav"},{"issue":"suppl 1","key":"10.1016\/j.biopsych.2011.11.023_bib38","doi-asserted-by":"crossref","first-page":"S33","DOI":"10.1016\/S1071-5576(99)00058-1","article-title":"Mechanisms of action and cross-talk between estrogen receptor and progesterone receptor pathways","volume":"7","author":"Katzenellenbogen","year":"2000","journal-title":"J Soc Gynecol Investig"},{"key":"10.1016\/j.biopsych.2011.11.023_bib39","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1007\/s10549-007-9618-4","article-title":"Estrogen receptors outside the nucleus in breast cancer","volume":"108","author":"Levin","year":"2008","journal-title":"Breast Cancer Res Treat"},{"key":"10.1016\/j.biopsych.2011.11.023_bib40","doi-asserted-by":"crossref","first-page":"1951","DOI":"10.1210\/me.2004-0390","article-title":"Integration of the extranuclear and nuclear actions of estrogen","volume":"19","author":"Levin","year":"2005","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib41","doi-asserted-by":"crossref","first-page":"1525","DOI":"10.1111\/j.1471-4159.2008.05491.x","article-title":"The roles of membrane estrogen receptor subtypes in modulating dopamine transporters in PC-12 cells","volume":"106","author":"Alyea","year":"2008","journal-title":"J Neurochem"},{"key":"10.1016\/j.biopsych.2011.11.023_bib42","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.steroids.2008.10.013","article-title":"Estradiol rapidly induces the translocation and activation of the intermediate conductance calcium activated potassium channel in human eccrine sweat gland cells","volume":"74","author":"Muchekehu","year":"2009","journal-title":"Steroids"},{"key":"10.1016\/j.biopsych.2011.11.023_bib43","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1016\/S0006-291X(05)81422-6","article-title":"Cell surface localization of a novel non-genomic progesterone receptor on the head of human sperm","volume":"181","author":"Blackmore","year":"1991","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.biopsych.2011.11.023_bib44","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1006\/frne.1996.0011","article-title":"Membrane sex-steroid receptors in the brain","volume":"17","author":"Ramirez","year":"1996","journal-title":"Front Neuroendocrinol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib45","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1002\/(SICI)1096-9861(19971201)388:4<507::AID-CNE1>3.0.CO;2-6","article-title":"Comparative distribution of estrogen receptor-alpha and -beta mRNA in the rat central nervous system","volume":"388","author":"Shughrue","year":"1997","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib46","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1016\/j.pbb.2004.03.023","article-title":"Antidepressant effects of ERbeta-selective estrogen receptor modulators in the forced swim test","volume":"78","author":"Walf","year":"2004","journal-title":"Pharmacol Biochem Behav"},{"key":"10.1016\/j.biopsych.2011.11.023_bib47","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1038\/sj.npp.1301416","article-title":"Antisense oligodeoxynucleotides for estrogen receptor-beta and alpha attenuate estradiol's modulation of affective and sexual behavior, respectively","volume":"33","author":"Walf","year":"2008","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.biopsych.2011.11.023_bib48","doi-asserted-by":"crossref","first-page":"974","DOI":"10.1037\/a0012749","article-title":"Estradiol or diarylpropionitrile decrease anxiety-like behavior of wildtype, but not estrogen receptor beta knockout, mice","volume":"122","author":"Walf","year":"2008","journal-title":"Behav Neurosci"},{"key":"10.1016\/j.biopsych.2011.11.023_bib49","doi-asserted-by":"crossref","first-page":"1598","DOI":"10.1038\/sj.npp.1300713","article-title":"ERbeta-selective estrogen receptor modulators produce antianxiety behavior when administered systemically to ovariectomized rats","volume":"30","author":"Walf","year":"2005","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.biopsych.2011.11.023_bib50","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s00213-003-1707-4","article-title":"Interaction between estrogens and antidepressants in the forced swimming test in rats","volume":"173","author":"Estrada-Camarena","year":"2004","journal-title":"Psychopharmacology (Berl)"},{"key":"10.1016\/j.biopsych.2011.11.023_bib51","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1677\/JOE-07-0017","article-title":"Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system","volume":"193","author":"Brailoiu","year":"2007","journal-title":"J Endocrinol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib52","doi-asserted-by":"crossref","first-page":"94","DOI":"10.1016\/j.neulet.2008.05.108","article-title":"Expression and intracellular distribution of the G protein-coupled receptor 30 in rat hippocampal formation","volume":"441","author":"Matsuda","year":"2008","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.biopsych.2011.11.023_bib53","doi-asserted-by":"crossref","first-page":"1599","DOI":"10.1016\/j.neuroscience.2008.11.028","article-title":"Extra-nuclear estrogen receptor GPR30 regulates serotonin function in rat hypothalamus","volume":"158","author":"Xu","year":"2009","journal-title":"Neuroscience"},{"key":"10.1016\/j.biopsych.2011.11.023_bib54","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1210\/rp.57.1.357","article-title":"Estrogen actions throughout the brain","volume":"57","author":"McEwen","year":"2002","journal-title":"Recent Prog Horm Res"},{"key":"10.1016\/j.biopsych.2011.11.023_bib55","doi-asserted-by":"crossref","first-page":"594","DOI":"10.1002\/jcp.20551","article-title":"Steering estrogen signals from the plasma membrane to the nucleus: Two sides of the coin","volume":"207","author":"Manavathi","year":"2006","journal-title":"J Cell Physiol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib56","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1210\/mend.14.10.0532","article-title":"Estrogen-induced activation of Erk-1 and Erk-2 requires the G protein-coupled receptor homolog, GPR30, and occurs via trans-activation of the epidermal growth factor receptor through release of HB-EGF","volume":"14","author":"Filardo","year":"2000","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib57","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1210\/mend.16.1.0758","article-title":"Estrogen action via the G protein-coupled receptor, GPR30: Stimulation of adenylyl cyclase and cAMP-mediated attenuation of the epidermal growth factor receptor-to-MAPK signaling axis","volume":"16","author":"Filardo","year":"2002","journal-title":"Mol Endocrinol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib58","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1016\/j.jsbmb.2006.09.023","article-title":"Progesterone and progestins: Effects on brain, allopregnanolone and beta-endorphin","volume":"102","author":"Pluchino","year":"2006","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib59","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1016\/j.yfrne.2008.02.001","article-title":"Progesterone receptors: Form and function in brain","volume":"29","author":"Brinton","year":"2008","journal-title":"Front Neuroendocrinol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib60","doi-asserted-by":"crossref","first-page":"178","DOI":"10.1016\/0006-8993(89)90955-4","article-title":"Regulation of high-affinity GABAA receptors in the dorsal hippocampus by estradiol and progesterone","volume":"487","author":"Schumacher","year":"1989","journal-title":"Brain Res"},{"key":"10.1016\/j.biopsych.2011.11.023_bib61","doi-asserted-by":"crossref","first-page":"820","DOI":"10.1101\/lm.1124708","article-title":"Progesterone regulation of synaptic transmission and plasticity in rodent hippocampus","volume":"15","author":"Foy","year":"2008","journal-title":"Learn Mem"},{"key":"10.1016\/j.biopsych.2011.11.023_bib62","doi-asserted-by":"crossref","first-page":"e3606","DOI":"10.1371\/journal.pone.0003606","article-title":"Progestin receptor-mediated reduction of anxiety-like behavior in male rats","volume":"3","author":"Auger","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.biopsych.2011.11.023_bib63","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/S0361-9230(02)00845-6","article-title":"Sex differences in the regulation of progesterone receptor isoforms expression in the rat brain","volume":"59","author":"Guerra-Araiza","year":"2002","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.biopsych.2011.11.023_bib64","doi-asserted-by":"crossref","first-page":"984","DOI":"10.1046\/j.1365-2826.2003.01088.x","article-title":"Changes in progesterone receptor isoforms content in the rat brain during the oestrous cycle and after oestradiol and progesterone treatments","volume":"15","author":"Guerra-Araiza","year":"2003","journal-title":"J Neuroendocrinol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib65","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1002\/cne.21826","article-title":"Ultrastructural localization of extranuclear progestin receptors in the rat hippocampal formation","volume":"511","author":"Waters","year":"2008","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib66","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.neulet.2007.02.039","article-title":"Raloxifene blocks estradiol induction of the serotonin transporter and 5-hydroxytryptamine2A receptor in female rat brain","volume":"417","author":"Sumner","year":"2007","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.biopsych.2011.11.023_bib67","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1038\/sj.npp.1300510","article-title":"Effects of ovarian steroids and raloxifene on proteins that synthesize, transport, and degrade serotonin in the raphe region of macaques","volume":"29","author":"Smith","year":"2004","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.biopsych.2011.11.023_bib68","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/BF02914268","article-title":"Ovarian steroids and serotonin neural function","volume":"18","author":"Bethea","year":"1998","journal-title":"Mol Neurobiol"},{"key":"10.1016\/j.biopsych.2011.11.023_bib69","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/0470870818.ch9","article-title":"Ovarian steroid action in the serotonin neural system of macaques","volume":"230","author":"Bethea","year":"2000","journal-title":"Novartis Found Symp"},{"key":"10.1016\/j.biopsych.2011.11.023_bib70","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1016\/S0006-3223(98)00162-0","article-title":"Estrogen-serotonin interactions: Implications for affective regulation","volume":"44","author":"Rubinow","year":"1998","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2011.11.023_bib71","first-page":"279","article-title":"Estrogen actions in the central nervous system","volume":"20","author":"McEwen","year":"1999","journal-title":"Endocr Rev"},{"key":"10.1016\/j.biopsych.2011.11.023_bib72","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0893-133X(00)00085-3","article-title":"Modulation by estrogen-receptor directed drugs of 5-hydroxytryptamine-2A receptors in rat brain","volume":"23","author":"Cyr","year":"2000","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.biopsych.2011.11.023_bib73","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1177\/1534582305277152","article-title":"Effect of estrogen-serotonin interactions on mood and cognition","volume":"4","author":"Amin","year":"2005","journal-title":"Behav Cogn Neurosci Rev"},{"key":"10.1016\/j.biopsych.2011.11.023_bib74","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1177\/1099800407305600","article-title":"The effects of estradiol on central serotonergic systems and its relationship to mood in women","volume":"9","author":"Lasiuk","year":"2007","journal-title":"Biol Res Nurs"},{"key":"10.1016\/j.biopsych.2011.11.023_bib75","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.tips.2008.12.006","article-title":"Estrogen-induced plasticity from cells to circuits: Predictions for cognitive function","volume":"30","author":"Brinton","year":"2009","journal-title":"Trends Pharmacol Sci"},{"key":"10.1016\/j.biopsych.2011.11.023_bib76","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1016\/S0025-7125(03)00061-0","article-title":"Gonadal steroids, selective serotonin reuptake inhibitors, and mood disorders in women","volume":"87","author":"Huttner","year":"2003","journal-title":"Med Clin North Am"},{"key":"10.1016\/j.biopsych.2011.11.023_bib77","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1176\/appi.ajgp.9.4.393","article-title":"Estrogen replacement therapy and antidepressant response to sertraline in older depressed women","volume":"9","author":"Schneider","year":"2001","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1016\/j.biopsych.2011.11.023_bib78","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1097\/00019442-199700520-00002","article-title":"Estrogen replacement and response to fluoxetine in a multicenter geriatric depression trial","volume":"5","author":"Schneider","year":"1997","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1016\/j.biopsych.2011.11.023_bib79","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/S0165-0327(98)00203-1","article-title":"Fluoxetine efficacy in menopausal women with and without estrogen replacement","volume":"55","author":"Amsterdam","year":"1999","journal-title":"J Affect Disord"},{"key":"10.1016\/j.biopsych.2011.11.023_bib80","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1016\/j.euroneuro.2006.11.001","article-title":"Response to SSRIs and role of the hormonal therapy in post-menopausal depression","volume":"17","author":"Zanardi","year":"2007","journal-title":"Eur Neuropsychopharmacol"}],"container-title":["Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322311011942?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322311011942?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T00:26:46Z","timestamp":1742257606000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006322311011942"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,4]]},"references-count":80,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2012,4]]}},"alternative-id":["S0006322311011942"],"URL":"https:\/\/doi.org\/10.1016\/j.biopsych.2011.11.023","relation":{},"ISSN":["0006-3223"],"issn-type":[{"value":"0006-3223","type":"print"}],"subject":[],"published":{"date-parts":[[2012,4]]}}}