{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T22:21:01Z","timestamp":1787696461792,"version":"build-2784847793"},"reference-count":38,"publisher":"Elsevier BV","issue":"11","license":[{"start":{"date-parts":[[2014,12,1]],"date-time":"2014-12-01T00:00:00Z","timestamp":1417392000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001659","name":"Deutsche Forschungsgemeinschaft","doi-asserted-by":"crossref","award":["STR 987\/2-1, 987\/2-3, SFB TRR 58 C07"],"award-info":[{"award-number":["STR 987\/2-1, 987\/2-3, SFB TRR 58 C07"]}],"id":[{"id":"10.13039\/501100001659","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biological Psychiatry"],"published-print":{"date-parts":[[2014,12]]},"DOI":"10.1016\/j.biopsych.2013.11.008","type":"journal-article","created":{"date-parts":[[2013,11,14]],"date-time":"2013-11-14T10:31:27Z","timestamp":1384425087000},"page":"869-877","source":"Crossref","is-referenced-by-count":37,"title":["Effects of Cognitive-Behavioral Therapy on Brain Responses to Subliminal and Supraliminal Threat and Their Functional Significance in Specific Phobia"],"prefix":"10.1016","volume":"76","author":[{"given":"Judith","family":"Lipka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marius","family":"Hoffmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wolfgang H.R.","family":"Miltner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Straube","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopsych.2013.11.008_bib1","doi-asserted-by":"crossref","first-page":"710","DOI":"10.1016\/j.cpr.2010.05.003","article-title":"Is cognitive-behavioral therapy more effective than other therapies? A meta-analytic review","volume":"30","author":"Tolin","year":"2010","journal-title":"Clin Psychol Rev"},{"key":"10.1016\/j.biopsych.2013.11.008_bib2","series-title":"What Works for Whom? A Critical Review of Psychotherapy Research, 2nd ed","author":"Roth","year":"2005"},{"key":"10.1016\/j.biopsych.2013.11.008_bib3","first-page":"239","article-title":"Effects on the brain of effective psychological treatments for anxiety disorders: A systematic review","volume":"38","author":"V\u00e1zquez Rivera","year":"2010","journal-title":"Actas Esp Psiquiatr"},{"key":"10.1016\/j.biopsych.2013.11.008_bib4","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1016\/j.biopsych.2007.04.024","article-title":"Amygdala hyperfunction in phobic fear normalizes after exposure","volume":"62","author":"Goossens","year":"2007","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2013.11.008_bib5","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S1053-8119(02)00030-7","article-title":"\u201cChange the mind and you change the brain\u201d: Effects of cognitive-behavioral therapy on the neural correlates of spider phobia","volume":"18","author":"Paquette","year":"2003","journal-title":"Neuroimage"},{"key":"10.1016\/j.biopsych.2013.11.008_bib6","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1007\/s00406-007-0754-y","article-title":"Symptom provocation and reduction in patients suffering from spider phobia: An fMRI study on exposure therapy","volume":"257","author":"Schienle","year":"2007","journal-title":"Eur Arch Psychiatry Clin Neurosci"},{"key":"10.1016\/j.biopsych.2013.11.008_bib7","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.neuroimage.2005.07.007","article-title":"Effects of cognitive-behavioral therapy on brain activation in specific phobia","volume":"29","author":"Straube","year":"2006","journal-title":"Neuroimage"},{"key":"10.1016\/j.biopsych.2013.11.008_bib8","doi-asserted-by":"crossref","first-page":"9203","DOI":"10.1073\/pnas.1205242109","article-title":"Exposure therapy triggers lasting reorganization of neural fear processing","volume":"109","author":"Hauner","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biopsych.2013.11.008_bib9","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1037\/1528-3542.4.4.340","article-title":"Fear and the amygdala: manipulation of awareness generates differential cerebral responses to phobic and fear-relevant (but nonfeared) stimuli","volume":"4","author":"Carlsson","year":"2004","journal-title":"Emotion"},{"key":"10.1016\/j.biopsych.2013.11.008_bib10","doi-asserted-by":"crossref","first-page":"472","DOI":"10.1016\/j.biopsych.2011.04.005","article-title":"Vigilance for threat interacts with amygdala responses to subliminal threat cues in specific phobia","volume":"70","author":"Lipka","year":"2011","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2013.11.008_bib11","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/2045-5380-1-12","article-title":"Amygdala activation to threat under attentional load in individuals with anxiety disorder","volume":"1","author":"Straube","year":"2011","journal-title":"Biol Mood Anxiety Disord"},{"key":"10.1016\/j.biopsych.2013.11.008_bib12","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1016\/j.biopsych.2005.06.013","article-title":"Neural mechanisms of automatic and direct processing of phobogenic stimuli in specific phobia","volume":"59","author":"Straube","year":"2006","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2013.11.008_bib13","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1037\/0033-295X.108.3.483","article-title":"Fears, phobias, and preparedness: Toward an evolved module of fear and fear learning","volume":"108","author":"\u00d6hman","year":"2001","journal-title":"Psychol Rev"},{"key":"10.1016\/j.biopsych.2013.11.008_bib14","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/0005-7967(95)00048-3","article-title":"Gender and age differences in the prevalence of specific fears and phobias","volume":"34","author":"Fredrikson","year":"1996","journal-title":"Behav Res Ther"},{"key":"10.1016\/j.biopsych.2013.11.008_bib15","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1001\/archpsyc.1996.01830020077009","article-title":"Agoraphobia, simple phobia, and social phobia in the National Comorbidity Survey","volume":"53","author":"Magee","year":"1996","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.biopsych.2013.11.008_bib16","series-title":"Strukturiertes Klinisches Interview f\u00fcr DSM-IV [Structured Clinical Interview for DSM-IV]","author":"Wittchen","year":"1997"},{"key":"10.1016\/j.biopsych.2013.11.008_bib17","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0005-7894(74)80008-0","article-title":"Psychometric description of some specific-fear questionnaires","volume":"5","author":"Klorman","year":"1974","journal-title":"Behav Ther"},{"key":"10.1016\/j.biopsych.2013.11.008_bib18","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/0028-3932(71)90067-4","article-title":"The assessment and analysis of handedness: The Edinburgh inventory","volume":"9","author":"Oldfield","year":"1971","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.biopsych.2013.11.008_bib19","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0005-7967(89)90113-7","article-title":"One-session treatment for specific phobias","volume":"27","author":"\u00d6st","year":"1989","journal-title":"Behav Res Ther"},{"key":"10.1016\/j.biopsych.2013.11.008_bib20","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/0146-6402(93)90012-Q","article-title":"Negative beliefs of spider phobics: A psychometric evaluation of the spider phobia beliefs questionnaire","volume":"15","author":"Arntz","year":"1993","journal-title":"Adv Behav Res Ther"},{"key":"10.1016\/j.biopsych.2013.11.008_bib21","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/0005-7967(84)90061-5","article-title":"Questionnaire dimensions of spider phobia","volume":"22","author":"Watts","year":"1984","journal-title":"Behav Res Ther"},{"key":"10.1016\/j.biopsych.2013.11.008_bib22","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0005-7894(05)80374-0","article-title":"One-session therapist-directed exposure vs. self-exposure in the treatment of spider phobia","volume":"22","author":"\u00d6st","year":"1991","journal-title":"Behav Ther"},{"key":"10.1016\/j.biopsych.2013.11.008_bib23","series-title":"Detection Theory: A User\u2019s Guide, 2nd ed","author":"Macmillan","year":"2005"},{"key":"10.1016\/j.biopsych.2013.11.008_bib24","doi-asserted-by":"crossref","first-page":"430","DOI":"10.1016\/S1053-8119(03)00073-9","article-title":"Optimized EPI for fMRI studies of the orbitofrontal cortex","volume":"19","author":"Deichmann","year":"2003","journal-title":"Neuroimage"},{"key":"10.1016\/j.biopsych.2013.11.008_bib25","series-title":"Co-planar Stereotaxic Atlas of the Human Brain","author":"Talairach","year":"1988"},{"key":"10.1016\/j.biopsych.2013.11.008_bib26","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1027\/0044-3409.216.1.49","article-title":"Adaptive measurement of individual change","volume":"216","author":"Weiss","year":"2008","journal-title":"Z Psychol"},{"key":"10.1016\/j.biopsych.2013.11.008_bib27","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1002\/1097-0193(200007)10:3<120::AID-HBM30>3.0.CO;2-8","article-title":"Automated Talairach atlas labels for functional brain mapping","volume":"10","author":"Lancaster","year":"2000","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.biopsych.2013.11.008_bib28","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1002\/hbm.20249","article-title":"Analysis of functional image analysis contest (FIAC) data with brainvoyager QX: From single-subject to cortically aligned group general linear model analysis and self-organizing group independent component analysis","volume":"27","author":"Goebel","year":"2006","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.biopsych.2013.11.008_bib29","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/cne.20520","article-title":"The organization of projections from the amygdala to visual cortical areas TE and V1 in the macaque monkey","volume":"486","author":"Freese","year":"2005","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.biopsych.2013.11.008_bib30","series-title":"Cognitive Neuroscience of Emotion","first-page":"129","article-title":"Cognitive-emotional interactions: Listen to the brain","author":"LeDoux","year":"2000"},{"key":"10.1016\/j.biopsych.2013.11.008_bib31","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.tics.2010.11.004","article-title":"Emotional processing in anterior cingulate and medial prefrontal cortex","volume":"15","author":"Etkin","year":"2011","journal-title":"Trends Cogn Sci"},{"key":"10.1016\/j.biopsych.2013.11.008_bib32","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1002\/cne.20749","article-title":"Neural mechanisms of autonomic, affective, and cognitive integration","volume":"493","author":"Critchley","year":"2005","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.biopsych.2013.11.008_bib33","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1515\/REVNEURO.2003.14.4.303","article-title":"The human amygdala: an evolved system for relevance detection","volume":"14","author":"Sander","year":"2003","journal-title":"Rev Neurosci"},{"key":"10.1016\/j.biopsych.2013.11.008_bib34","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1146\/annurev.neuro.23.1.155","article-title":"Emotion circuits in the brain","volume":"23","author":"LeDoux","year":"2000","journal-title":"Annu Rev Neurosci"},{"key":"10.1016\/j.biopsych.2013.11.008_bib35","doi-asserted-by":"crossref","first-page":"1344","DOI":"10.1038\/sj.npp.1300186","article-title":"Habituation of rostral anterior cingulate cortex to repeated emotionally salient pictures","volume":"28","author":"Phan","year":"2003","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.biopsych.2013.11.008_bib36","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1159\/000077948","article-title":"Hemodynamic effects of negative emotional pictures\u2014a test-retest analysis","volume":"50","author":"Stark","year":"2004","journal-title":"Neuropsychobiology"},{"key":"10.1016\/j.biopsych.2013.11.008_bib37","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1016\/j.neuroimage.2009.12.083","article-title":"A unique role for the human amygdala in novelty detection","volume":"50","author":"Blackford","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.biopsych.2013.11.008_bib38","doi-asserted-by":"crossref","first-page":"621","DOI":"10.4088\/JCP.v69n0415","article-title":"Cognitive-behavioral therapy for adult anxiety disorders: a meta-analysis of randomized placebo-controlled trials","volume":"69","author":"Hofmann","year":"2008","journal-title":"J Clin Psychiatry"}],"container-title":["Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000632231300989X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S000632231300989X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,10,10]],"date-time":"2018-10-10T15:52:28Z","timestamp":1539186748000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S000632231300989X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,12]]},"references-count":38,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2014,12]]}},"alternative-id":["S000632231300989X"],"URL":"https:\/\/doi.org\/10.1016\/j.biopsych.2013.11.008","relation":{},"ISSN":["0006-3223"],"issn-type":[{"value":"0006-3223","type":"print"}],"subject":[],"published":{"date-parts":[[2014,12]]}}}