{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T16:54:02Z","timestamp":1793724842104,"version":"4.6.1"},"reference-count":86,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2015,8,1]],"date-time":"2015-08-01T00:00:00Z","timestamp":1438387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2014,12,17]],"date-time":"2014-12-17T00:00:00Z","timestamp":1418774400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biological Psychiatry"],"published-print":{"date-parts":[[2015,8]]},"DOI":"10.1016\/j.biopsych.2014.12.009","type":"journal-article","created":{"date-parts":[[2014,12,19]],"date-time":"2014-12-19T20:56:38Z","timestamp":1419022598000},"page":"231-239","source":"Crossref","is-referenced-by-count":179,"title":["MicroRNA and Posttranscriptional Dysregulation in Psychiatry"],"prefix":"10.1016","volume":"78","author":[{"given":"Michael","family":"Geaghan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murray J.","family":"Cairns","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopsych.2014.12.009_bib1","doi-asserted-by":"crossref","first-page":"4645","DOI":"10.1242\/dev.02070","article-title":"microPrimer: The biogenesis and function of microRNA","volume":"132","author":"Du","year":"2005","journal-title":"Development"},{"key":"10.1016\/j.biopsych.2014.12.009_bib2","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0092-8674(04)00045-5","article-title":"MicroRNAs: Genomics, biogenesis, mechanism, and function","volume":"116","author":"Bartel","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.biopsych.2014.12.009_bib3","doi-asserted-by":"crossref","first-page":"1902","DOI":"10.1101\/gr.2722704","article-title":"Identification of mammalian microRNA host genes and transcription units","volume":"14","author":"Rodriguez","year":"2004","journal-title":"Genome Res"},{"key":"10.1016\/j.biopsych.2014.12.009_bib4","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1038\/nature01957","article-title":"The nuclear RNase III Drosha initiates microRNA processing","volume":"425","author":"Lee","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.biopsych.2014.12.009_bib5","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1038\/nature03120","article-title":"The Microprocessor complex mediates the genesis of microRNAs","volume":"432","author":"Gregory","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.biopsych.2014.12.009_bib6","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.cell.2005.10.022","article-title":"Human RISC couples microRNA biogenesis and posttranscriptional gene silencing","volume":"123","author":"Gregory","year":"2005","journal-title":"Cell"},{"key":"10.1016\/j.biopsych.2014.12.009_bib7","doi-asserted-by":"crossref","first-page":"D152","DOI":"10.1093\/nar\/gkq1027","article-title":"miRBase: integrating microRNA annotation and deep-sequencing data","volume":"39","author":"Kozomara","year":"2011","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.biopsych.2014.12.009_bib8","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1016\/S0092-8674(03)01018-3","article-title":"Prediction of mammalian microRNA targets","volume":"115","author":"Lewis","year":"2003","journal-title":"Cell"},{"key":"10.1016\/j.biopsych.2014.12.009_bib9","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1186\/1471-2164-13-561","article-title":"Alternative mRNA fates identified in microRNA-associated transcriptome analysis","volume":"13","author":"Carroll","year":"2012","journal-title":"BMC Genomics"},{"key":"10.1016\/j.biopsych.2014.12.009_bib10","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1038\/nature03315","article-title":"Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs","volume":"433","author":"Lim","year":"2005","journal-title":"Nature"},{"key":"10.1016\/j.biopsych.2014.12.009_bib11","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1126\/science.1109020","article-title":"MicroRNAs regulate brain morphogenesis in zebrafish","volume":"308","author":"Giraldez","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.biopsych.2014.12.009_bib12","doi-asserted-by":"crossref","first-page":"4322","DOI":"10.1523\/JNEUROSCI.4815-07.2008","article-title":"Conditional loss of Dicer disrupts cellular and tissue morphogenesis in the cortex and hippocampus","volume":"28","author":"Davis","year":"2008","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2014.12.009_bib13","doi-asserted-by":"crossref","first-page":"5614","DOI":"10.1073\/pnas.0801689105","article-title":"Dicer loss in striatal neurons produces behavioral and neuroanatomical phenotypes in the absence of neurodegeneration","volume":"105","author":"Cuellar","year":"2008","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biopsych.2014.12.009_bib14","doi-asserted-by":"crossref","first-page":"R27","DOI":"10.1186\/gb-2007-8-2-r27","article-title":"microRNA expression in the prefrontal cortex of individuals with schizophrenia and schizoaffective disorder","volume":"8","author":"Perkins","year":"2007","journal-title":"Genome Biol"},{"key":"10.1016\/j.biopsych.2014.12.009_bib15","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1038\/mp.2009.84","article-title":"Schizophrenia is associated with an increase in cortical microRNA biogenesis","volume":"15","author":"Beveridge","year":"2010","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.biopsych.2014.12.009_bib16","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1093\/hmg\/ddn005","article-title":"Dysregulation of miRNA 181b in the temporal cortex in schizophrenia","volume":"17","author":"Beveridge","year":"2008","journal-title":"Hum Mol Genet"},{"key":"10.1016\/j.biopsych.2014.12.009_bib17","doi-asserted-by":"crossref","first-page":"e51436","DOI":"10.1371\/journal.pone.0051436","article-title":"An epigenetic feedback regulatory loop involving microRNA-195 and MBD1 governs neural stem cell differentiation","volume":"8","author":"Liu","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.biopsych.2014.12.009_bib18","doi-asserted-by":"crossref","first-page":"e20038","DOI":"10.1371\/journal.pone.0020038","article-title":"The role of miR-103 and miR-107 in regulation of CDK5R1 expression and in cellular migration","volume":"6","author":"Moncini","year":"2011","journal-title":"PloS One"},{"key":"10.1016\/j.biopsych.2014.12.009_bib19","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1002\/ajmg.a.30984","article-title":"Clinical features of 78 adults with 22q11 deletion syndrome","volume":"138","author":"Bassett","year":"2005","journal-title":"Am J Med Genet A"},{"key":"10.1016\/j.biopsych.2014.12.009_bib20","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/S0006-291X(03)00554-0","article-title":"Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region","volume":"304","author":"Shiohama","year":"2003","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.biopsych.2014.12.009_bib21","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.biopsych.2010.09.030","article-title":"Upregulation of dicer and microRNA expression in the dorsolateral prefrontal cortex Brodmann area 46 in schizophrenia","volume":"69","author":"Santarelli","year":"2011","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2014.12.009_bib22","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.schres.2010.07.002","article-title":"MicroRNA expression profiling in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders","volume":"124","author":"Kim","year":"2010","journal-title":"Schizophr Res"},{"key":"10.1016\/j.biopsych.2014.12.009_bib23","doi-asserted-by":"crossref","first-page":"e62509","DOI":"10.1371\/journal.pone.0062509","article-title":"miR-132\/212 knockout mice reveal roles for these miRNAs in regulating cortical synaptic transmission and plasticity","volume":"8","author":"Remenyi","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.biopsych.2014.12.009_bib24","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1002\/hipo.22123","article-title":"In vivo knockdown of hippocampal miR-132 expression impairs memory acquisition of trace fear conditioning","volume":"23","author":"Wang","year":"2013","journal-title":"Hippocampus"},{"key":"10.1016\/j.biopsych.2014.12.009_bib25","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1038\/mp.2011.78","article-title":"Imprinted DLK1-DIO3 region of 14q32 defines a schizophrenia-associated miRNA signature in peripheral blood mononuclear cells","volume":"17","author":"Gardiner","year":"2012","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.biopsych.2014.12.009_bib26","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1042\/BC20070126","article-title":"Non-coding RNAs in imprinted gene clusters","volume":"100","author":"Royo","year":"2008","journal-title":"Biol Cell"},{"key":"10.1016\/j.biopsych.2014.12.009_bib27","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1038\/emboj.2009.10","article-title":"Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels","volume":"28","author":"Fiore","year":"2009","journal-title":"EMBO J"},{"key":"10.1016\/j.biopsych.2014.12.009_bib28","doi-asserted-by":"crossref","first-page":"e21635","DOI":"10.1371\/journal.pone.0021635","article-title":"MicroRNA expression aberration as potential peripheral blood biomarkers for schizophrenia","volume":"6","author":"Lai","year":"2011","journal-title":"PloS One"},{"key":"10.1016\/j.biopsych.2014.12.009_bib29","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.jpsychires.2011.09.010","article-title":"Aberrant expression of serum miRNAs in schizophrenia","volume":"46","author":"Shi","year":"2012","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.biopsych.2014.12.009_bib30","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1038\/ng.940","article-title":"Genome-wide association study identifies five new schizophrenia loci","volume":"43","author":"Ripke","year":"2011","journal-title":"Nat Genet"},{"key":"10.1016\/j.biopsych.2014.12.009_bib31","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1038\/nature13595","article-title":"Biological insights from 108 schizophrenia-associated genetic loci","volume":"511","author":"Ripke","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.biopsych.2014.12.009_bib32","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1038\/ncomms1532","article-title":"miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells","volume":"2","author":"Sun","year":"2011","journal-title":"Nat Commun"},{"key":"10.1016\/j.biopsych.2014.12.009_bib33","doi-asserted-by":"crossref","first-page":"58","DOI":"10.3389\/fgene.2013.00058","article-title":"Potential impact of miR-137 and its targets in schizophrenia","volume":"4","author":"Wright","year":"2013","journal-title":"Front Genet"},{"key":"10.1016\/j.biopsych.2014.12.009_bib34","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1016\/j.jpsychires.2013.05.021","article-title":"Analysis of miR-137 expression and rs1625579 in dorsolateral prefrontal cortex","volume":"47","author":"Guella","year":"2013","journal-title":"J Psychiatr Res"},{"key":"10.1016\/j.biopsych.2014.12.009_bib35","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1016\/j.biopsych.2013.06.016","article-title":"Schizophrenia miR-137 locus risk genotype is associated with dorsolateral prefrontal cortex hyperactivation","volume":"75","author":"van Erp","year":"2014","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2014.12.009_bib36","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1001\/archgenpsychiatry.2010.107","article-title":"Modification of cognitive performance in schizophrenia by complexin 2 gene polymorphisms","volume":"67","author":"Begemann","year":"2010","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.biopsych.2014.12.009_bib37","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1093\/oxfordjournals.schbul.a006887","article-title":"Neural development, cell-cell signaling, and the \u201ctwo-hit\u201d hypothesis of schizophrenia","volume":"27","author":"Maynard","year":"2001","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.biopsych.2014.12.009_bib38","doi-asserted-by":"crossref","first-page":"e452","DOI":"10.1038\/tp.2014.99","article-title":"Alteration of imprinted Dlk1-Dio3 miRNA cluster expression in the entorhinal cortex induced by maternal immune activation and adolescent cannabinoid exposure","volume":"4","author":"Hollins","year":"2014","journal-title":"Transl Psychiatry"},{"key":"10.1016\/j.biopsych.2014.12.009_bib39","doi-asserted-by":"crossref","first-page":"6983","DOI":"10.1523\/JNEUROSCI.0679-08.2008","article-title":"Deletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function","volume":"28","author":"Samuels","year":"2008","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2014.12.009_bib40","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0920-9964(98)00179-0","article-title":"Increased expression of Wnt-1 in schizophrenic brains","volume":"38","author":"Miyaoka","year":"1999","journal-title":"Schizophr Res"},{"key":"10.1016\/j.biopsych.2014.12.009_bib41","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.biopsych.2010.09.039","article-title":"Altered microRNA expression profiles in postmortem brain samples from individuals with schizophrenia and bipolar disorder","volume":"69","author":"Moreau","year":"2011","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2014.12.009_bib42","doi-asserted-by":"crossref","first-page":"3125","DOI":"10.1073\/pnas.1113793109","article-title":"MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function","volume":"109","author":"Miller","year":"2012","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biopsych.2014.12.009_bib43","doi-asserted-by":"crossref","first-page":"e86469","DOI":"10.1371\/journal.pone.0086469","article-title":"Expression of microRNAs and other small RNAs in prefrontal cortex in schizophrenia, bipolar disorder and depressed subjects","volume":"9","author":"Smalheiser","year":"2014","journal-title":"PloS One"},{"key":"10.1016\/j.biopsych.2014.12.009_bib44","doi-asserted-by":"crossref","first-page":"e48814","DOI":"10.1371\/journal.pone.0048814","article-title":"Differential expression of exosomal microRNAs in prefrontal cortices of schizophrenia and bipolar disorder patients","volume":"8","author":"Banigan","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.biopsych.2014.12.009_bib45","doi-asserted-by":"crossref","first-page":"2720","DOI":"10.1038\/npp.2012.137","article-title":"Impact of a microRNA MIR137 susceptibility variant on brain function in people at high genetic risk of schizophrenia or bipolar disorder","volume":"37","author":"Whalley","year":"2012","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.biopsych.2014.12.009_bib46","doi-asserted-by":"crossref","first-page":"e82895","DOI":"10.1371\/journal.pone.0082895","article-title":"Valproic acid causes proteasomal degradation of DICER and influences miRNA expression","volume":"8","author":"Zhang","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.biopsych.2014.12.009_bib47","doi-asserted-by":"crossref","first-page":"807","DOI":"10.3109\/07420528.2014.906445","article-title":"Association between circadian genes, bipolar disorders and chronotypes","volume":"31","author":"Etain","year":"2014","journal-title":"Chronobiol Int"},{"key":"10.1016\/j.biopsych.2014.12.009_bib48","doi-asserted-by":"crossref","first-page":"1790","DOI":"10.1002\/elps.200900664","article-title":"Analysis of a polymorphic microRNA target site in the purinergic receptor P2RX7 gene","volume":"31","author":"Rahman","year":"2010","journal-title":"Electrophoresis"},{"key":"10.1016\/j.biopsych.2014.12.009_bib49","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/j.pneurobio.2006.03.007","article-title":"P2X7 receptors in the nervous system","volume":"78","author":"Sperlagh","year":"2006","journal-title":"Prog Neurobiol"},{"key":"10.1016\/j.biopsych.2014.12.009_bib50","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1016\/j.jad.2010.05.019","article-title":"A polymorphism in the microRNA-30e precursor associated with major depressive disorder risk and P300 waveform","volume":"127","author":"Xu","year":"2010","journal-title":"J Affect Disord"},{"key":"10.1016\/j.biopsych.2014.12.009_bib51","doi-asserted-by":"crossref","first-page":"1499","DOI":"10.1089\/dna.2012.1660","article-title":"Genetic variations in microRNA processing genes are associated with susceptibility in depression","volume":"31","author":"He","year":"2012","journal-title":"DNA Cell Biol"},{"key":"10.1016\/j.biopsych.2014.12.009_bib52","doi-asserted-by":"crossref","first-page":"e33201","DOI":"10.1371\/journal.pone.0033201","article-title":"MicroRNA expression is down-regulated and reorganized in prefrontal cortex of depressed suicide subjects","volume":"7","author":"Smalheiser","year":"2012","journal-title":"PloS One"},{"key":"10.1016\/j.biopsych.2014.12.009_bib53","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1017\/S1461145710001628","article-title":"MicroRNA expression in rat brain exposed to repeated inescapable shock: Differential alterations in learned helplessness vs. non-learned helplessness","volume":"14","author":"Smalheiser","year":"2011","journal-title":"Int J Neuropsychopharmacol"},{"key":"10.1016\/j.biopsych.2014.12.009_bib54","doi-asserted-by":"crossref","first-page":"25053","DOI":"10.1074\/jbc.M700501200","article-title":"MicroRNA (miRNA) transcriptome of mouse retina and identification of a sensory organ-specific miRNA cluster","volume":"282","author":"Xu","year":"2007","journal-title":"J Biol Chem"},{"issue":"suppl 2","key":"10.1016\/j.biopsych.2014.12.009_bib55","doi-asserted-by":"crossref","first-page":"15","DOI":"10.2165\/11318630-000000000-00000","article-title":"Disruption of the circadian timing systems: Molecular mechanisms in mood disorders","volume":"23","author":"Mendlewicz","year":"2009","journal-title":"CNS Drugs"},{"key":"10.1016\/j.biopsych.2014.12.009_bib56","doi-asserted-by":"crossref","first-page":"e63648","DOI":"10.1371\/journal.pone.0063648","article-title":"Alterations of serum levels of BDNF-related miRNAs in patients with depression","volume":"8","author":"Li","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.biopsych.2014.12.009_bib57","doi-asserted-by":"crossref","first-page":"438","DOI":"10.12659\/MSM.883935","article-title":"MicroRNA-132 may play a role in coexistence of depression and cardiovascular disease: A hypothesis","volume":"19","author":"Zheng","year":"2013","journal-title":"Med Sci Monit"},{"key":"10.1016\/j.biopsych.2014.12.009_bib58","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1016\/j.neuron.2007.05.017","article-title":"microRNA modulation of circadian-clock period and entrainment","volume":"54","author":"Cheng","year":"2007","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2014.12.009_bib59","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1007\/s10048-008-0133-5","article-title":"Heterogeneous dysregulation of microRNAs across the autism spectrum","volume":"9","author":"Abu-Elneel","year":"2008","journal-title":"Neurogenetics"},{"key":"10.1016\/j.biopsych.2014.12.009_bib60","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1007\/s10048-009-0179-z","article-title":"Comment on the article \u201cHeterogeneous dysregulation of microRNAs across the autism spectrum\u201d by Abu-Elneel et al","volume":"10","author":"Buyske","year":"2009","journal-title":"Neurogenetics"},{"key":"10.1016\/j.biopsych.2014.12.009_bib61","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1002\/aur.33","article-title":"Feasibility and relevance of examining lymphoblastoid cell lines to study role of microRNAs in autism","volume":"1","author":"Talebizadeh","year":"2008","journal-title":"Autism Res"},{"key":"10.1016\/j.biopsych.2014.12.009_bib62","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1186\/gm144","article-title":"Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines","volume":"2","author":"Sarachana","year":"2010","journal-title":"Genome Med"},{"key":"10.1016\/j.biopsych.2014.12.009_bib63","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.brainres.2010.09.046","article-title":"Gene and miRNA expression profiles in autism spectrum disorders","volume":"1380","author":"Ghahramani Seno","year":"2011","journal-title":"Brain Res"},{"key":"10.1016\/j.biopsych.2014.12.009_bib64","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1186\/1755-8166-7-27","article-title":"Short stature, digit anomalies and dysmorphic facial features are associated with the duplication of miR-17 ~ 92 cluster","volume":"7","author":"Hemmat","year":"2014","journal-title":"Mol Cytogenet"},{"key":"10.1016\/j.biopsych.2014.12.009_bib65","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.ejmg.2013.06.001","article-title":"Post-axial polydactyly type A2, overgrowth and autistic traits associated with a chromosome 13q31.3 microduplication encompassing miR-17-92 and GPC5","volume":"56","author":"Kannu","year":"2013","journal-title":"Eur J Med Genet"},{"key":"10.1016\/j.biopsych.2014.12.009_bib66","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1136\/jmg.2008.059907","article-title":"Microdeletion\/duplication at 15q13.2q13.3 among individuals with features of autism and other neuropsychiatric disorders","volume":"46","author":"Miller","year":"2009","journal-title":"J Med Genet"},{"key":"10.1016\/j.biopsych.2014.12.009_bib67","doi-asserted-by":"crossref","first-page":"e56781","DOI":"10.1371\/journal.pone.0056781","article-title":"Insights on the functional impact of microRNAs present in autism-associated copy number variants","volume":"8","author":"Vaishnavi","year":"2013","journal-title":"PloS One"},{"key":"10.1016\/j.biopsych.2014.12.009_bib68","doi-asserted-by":"crossref","first-page":"e90947","DOI":"10.1371\/journal.pone.0090947","article-title":"Assessing the impact of copy number variants on miRNA genes in autism by Monte Carlo simulation","volume":"9","author":"Marrale","year":"2014","journal-title":"PloS One"},{"key":"10.1016\/j.biopsych.2014.12.009_bib69","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1038\/nature08956","article-title":"Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles","volume":"464","author":"Davis","year":"2010","journal-title":"Nature"},{"key":"10.1016\/j.biopsych.2014.12.009_bib70","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1161\/CIRCRESAHA.111.244442","article-title":"Inhibition of miR-15 protects against cardiac ischemic injury","volume":"110","author":"Hullinger","year":"2012","journal-title":"Circ Res"},{"key":"10.1016\/j.biopsych.2014.12.009_bib71","doi-asserted-by":"crossref","first-page":"2885","DOI":"10.1093\/nar\/gkm024","article-title":"Specificity, duplex degradation and subcellular localization of antagomirs","volume":"35","author":"Krutzfeldt","year":"2007","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.biopsych.2014.12.009_bib72","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/j.nbd.2011.09.012","article-title":"miR-181 regulates GRP78 and influences outcome from cerebral ischemia in vitro and in vivo","volume":"45","author":"Ouyang","year":"2012","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.biopsych.2014.12.009_bib73","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.nbd.2009.12.021","article-title":"miR-497 regulates neuronal death in mouse brain after transient focal cerebral ischemia","volume":"38","author":"Yin","year":"2010","journal-title":"Neurobiol Dis"},{"key":"10.1016\/j.biopsych.2014.12.009_bib74","doi-asserted-by":"crossref","first-page":"848","DOI":"10.1038\/mp.2013.93","article-title":"Identification of differentially expressed microRNAs across the developing human brain","volume":"19","author":"Ziats","year":"2014","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.biopsych.2014.12.009_bib75","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1093\/schbul\/sbs198","article-title":"Maturation of the human dorsolateral prefrontal cortex coincides with a dynamic shift in microRNA expression","volume":"40","author":"Beveridge","year":"2014","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.biopsych.2014.12.009_bib76","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1186\/1471-2164-15-777","article-title":"Ontogeny of small RNA in the regulation of mammalian brain development","volume":"15","author":"Hollins","year":"2014","journal-title":"BMC Genom"},{"key":"10.1016\/j.biopsych.2014.12.009_bib77","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1002\/dneu.22113","article-title":"Identification of axon-enriched microRNAs localized to growth cones of cortical neurons","volume":"74","author":"Sasaki","year":"2014","journal-title":"Dev Neurobiol"},{"key":"10.1016\/j.biopsych.2014.12.009_bib78","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.brainres.2007.07.088","article-title":"Dicer expression and localization in post-mitotic neurons","volume":"1175","author":"Barbato","year":"2007","journal-title":"Brain Res"},{"key":"10.1016\/j.biopsych.2014.12.009_bib79","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1038\/mp.2012.84","article-title":"Genome-wide supported variant MIR137 and severe negative symptoms predict membership of an impaired cognitive subtype of schizophrenia","volume":"18","author":"Green","year":"2013","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.biopsych.2014.12.009_bib80","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1093\/schbul\/sbr177","article-title":"Expression of NPAS3 in the human cortex and evidence of its posttranscriptional regulation by miR-17 during development, with implications for schizophrenia","volume":"39","author":"Wong","year":"2013","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.biopsych.2014.12.009_bib81","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.schres.2010.02.1070","article-title":"MicroRNAs and target site screening reveals a pre-microRNA-30e variant associated with schizophrenia","volume":"119","author":"Xu","year":"2010","journal-title":"Schizophr Res"},{"key":"10.1016\/j.biopsych.2014.12.009_bib82","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1093\/schbul\/sbq091","article-title":"Gender-specific reduction of estrogen-sensitive small RNA, miR-30b, in subjects with schizophrenia","volume":"38","author":"Mellios","year":"2012","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.biopsych.2014.12.009_bib83","doi-asserted-by":"crossref","first-page":"563","DOI":"10.1038\/mp.2009.2","article-title":"Chromosome 8p as a potential hub for developmental neuropsychiatric disorders: Implications for schizophrenia, autism and cancer","volume":"14","author":"Tabares-Seisdedos","year":"2009","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.biopsych.2014.12.009_bib84","doi-asserted-by":"crossref","first-page":"293","DOI":"10.3389\/fgene.2012.00293","article-title":"Incorporating information of microRNAs into pathway analysis in a genome-wide association study of bipolar disorder","volume":"3","author":"Shih","year":"2012","journal-title":"Front Genet"},{"key":"10.1016\/j.biopsych.2014.12.009_bib85","doi-asserted-by":"crossref","first-page":"e185","DOI":"10.1038\/tp.2012.112","article-title":"Responder and nonresponder patients exhibit different peripheral transcriptional signatures during major depressive episode","volume":"2","author":"Belzeaux","year":"2012","journal-title":"Transl Psychiatry"},{"key":"10.1016\/j.biopsych.2014.12.009_bib86","first-page":"1585","article-title":"Screening of specific microRNA in hippocampus of depression model rats and intervention effect of Chaihu Shugan San [in Chinese]","volume":"38","author":"Cao","year":"2013","journal-title":"Zhongguo Zhong Yao Za Zhi"}],"container-title":["Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322314009895?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322314009895?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,26]],"date-time":"2018-09-26T17:24:10Z","timestamp":1537982650000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006322314009895"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,8]]},"references-count":86,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,8]]}},"alternative-id":["S0006322314009895"],"URL":"https:\/\/doi.org\/10.1016\/j.biopsych.2014.12.009","relation":{},"ISSN":["0006-3223"],"issn-type":[{"value":"0006-3223","type":"print"}],"subject":[],"published":{"date-parts":[[2015,8]]}}}