{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:46:35Z","timestamp":1791305195571,"version":"4.3.1"},"reference-count":60,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Italian Ministry of Health Young Researcher","award":["GR-2010-2312442"],"award-info":[{"award-number":["GR-2010-2312442"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biological Psychiatry"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.biopsych.2015.10.013","type":"journal-article","created":{"date-parts":[[2015,11,2]],"date-time":"2015-11-02T19:40:16Z","timestamp":1446493216000},"page":"786-795","source":"Crossref","is-referenced-by-count":193,"title":["Alterations in Amygdala-Prefrontal Functional Connectivity Account for Excessive Worry and Autonomic Dysregulation in Generalized Anxiety Disorder"],"prefix":"10.1016","volume":"80","author":[{"given":"Elena","family":"Makovac","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frances","family":"Meeten","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2348-7109","authenticated-orcid":false,"given":"David R.","family":"Watson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aleksandra","family":"Herman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah N.","family":"Garfinkel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hugo","family":"D. Critchley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5240-4387","authenticated-orcid":false,"given":"Cristina","family":"Ottaviani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopsych.2015.10.013_bib1","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1002\/da.20257","article-title":"Human and economic burden of generalized anxiety disorder","volume":"25","author":"Hoffman","year":"2008","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.biopsych.2015.10.013_bib2","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1111\/j.1468-1331.2011.03590.x","article-title":"CDBE2010 study group; European Brain Council. The economic cost of brain disorders in Europe","volume":"19","author":"Olesen","year":"2012","journal-title":"Eur J Neurol"},{"key":"10.1016\/j.biopsych.2015.10.013_bib3","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1023\/A:1025048802629","article-title":"The emotional brain, fear, and the amygdala","volume":"23","author":"LeDoux","year":"2003","journal-title":"Cell Mol Neurobiol"},{"key":"10.1016\/j.biopsych.2015.10.013_bib4","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1016\/j.jad.2014.01.022","article-title":"Neural structures, functioning and connectivity in generalized anxiety disorder and interaction with neuroendocrine systems: A systematic review","volume":"158","author":"Hilbert","year":"2014","journal-title":"J Affect Disord"},{"key":"10.1016\/j.biopsych.2015.10.013_bib5","doi-asserted-by":"crossref","first-page":"1361","DOI":"10.1001\/archgenpsychiatry.2009.104","article-title":"Disrupted amygdalar subregion functional connectivity and evidence of a compensatory network in generalized anxiety disorder","volume":"66","author":"Etkin","year":"2009","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.biopsych.2015.10.013_bib6","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1001\/archpsyc.65.5.568","article-title":"Amygdala and ventrolateral prefrontal cortex activation to masked angry faces in children and adolescents with generalized anxiety disorder","volume":"65","author":"Monk","year":"2008","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.biopsych.2015.10.013_bib7","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.jaac.2012.12.010","article-title":"Intrinsic functional connectivity of amygdala-based networks in adolescent generalized anxiety disorder","volume":"52","author":"Roy","year":"2013","journal-title":"J Am Acad Child Adolesc Psychiatry"},{"key":"10.1016\/j.biopsych.2015.10.013_bib8","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/s13587-014-0015-4","article-title":"Aberrant amygdala functional connectivity at rest in pediatric anxiety disorders","volume":"4","author":"Hamm","year":"2014","journal-title":"Biol Mood Anxiety Disord"},{"key":"10.1016\/j.biopsych.2015.10.013_bib9","doi-asserted-by":"crossref","first-page":"1475","DOI":"10.1017\/S0033291712002383","article-title":"Prefrontal dysfunction during emotion regulation in generalized anxiety and panic disorders","volume":"43","author":"Ball","year":"2013","journal-title":"Psychol Med"},{"key":"10.1016\/j.biopsych.2015.10.013_bib10","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1007\/s00213-006-0542-9","article-title":"fMRI predictors of treatment outcome in pediatric anxiety disorders","volume":"191","author":"McClure","year":"2007","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.biopsych.2015.10.013_bib11","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1093\/scan\/nsm029","article-title":"Amygdala-frontal connectivity during emotion regulation","volume":"2","author":"Banks","year":"2007","journal-title":"Soc Cogn Affect Neurosci"},{"key":"10.1016\/j.biopsych.2015.10.013_bib12","doi-asserted-by":"crossref","first-page":"15726","DOI":"10.1523\/JNEUROSCI.1856-10.2010","article-title":"Acute and sustained effects of cognitive emotion regulation in major depression","volume":"30","author":"Erk","year":"2010","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2015.10.013_bib13","series-title":"Generalized Anxiety Disorder: Advances in Research and Practice","first-page":"77","article-title":"Avoidance theory of worry and generalized anxiety disorder","author":"Borkovec","year":"2004"},{"key":"10.1016\/j.biopsych.2015.10.013_bib14","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1002\/cne.20749","article-title":"Neural mechanisms of autonomic, affective, and cognitive integration","volume":"493","author":"Critchley","year":"2005","journal-title":"J Comp Neurol"},{"key":"10.1016\/j.biopsych.2015.10.013_bib15","doi-asserted-by":"crossref","first-page":"1700","DOI":"10.1002\/hbm.21315","article-title":"Brain systems for baroreflex suppression during stress in humans","volume":"33","author":"Gianaros","year":"2012","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.biopsych.2015.10.013_bib16","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1037\/bul0000036","article-title":"Physiological concomitants of perseverative cognition: A systematic review and meta-analysis","volume":"142","author":"Ottaviani","year":"2016","journal-title":"Psychol Bull"},{"key":"10.1016\/j.biopsych.2015.10.013_bib17","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/0006-3223(95)00136-0","article-title":"Autonomic characteristics of generalized anxiety disorder and worry","volume":"39","author":"Thayer","year":"1996","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2015.10.013_bib18","doi-asserted-by":"crossref","first-page":"914","DOI":"10.1162\/jocn_a_00512","article-title":"Resting state correlates of subdimensions of anxious affect","volume":"26","author":"Bijsterbosch","year":"2014","journal-title":"J Cogn Neurosci"},{"key":"10.1016\/j.biopsych.2015.10.013_bib19","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.jagp.2014.05.003","article-title":"Emotion reactivity and regulation in late-life generalized anxiety disorder: Functional connectivity at baseline and post-treatment","volume":"23","author":"Andreescu","year":"2015","journal-title":"Am J Geriatr Psychiatry"},{"key":"10.1016\/j.biopsych.2015.10.013_bib20","doi-asserted-by":"crossref","first-page":"2139","DOI":"10.1093\/brain\/awg216","article-title":"Human cingulate cortex and autonomic control: Converging neuroimaging and clinical evidence","volume":"126","author":"Critchley","year":"2003","journal-title":"Brain"},{"key":"10.1016\/j.biopsych.2015.10.013_bib21","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/j.neuroimage.2012.11.038","article-title":"Association between heart rate variability and fluctuations in resting-state functional connectivity","volume":"68","author":"Chang","year":"2013","journal-title":"Neuroimage"},{"key":"10.1016\/j.biopsych.2015.10.013_bib22","doi-asserted-by":"crossref","first-page":"10503","DOI":"10.1523\/JNEUROSCI.1103-13.2013","article-title":"The autonomic brain: An activation likelihood estimation meta-analysis for central processing of autonomic function","volume":"33","author":"Beissner","year":"2013","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2015.10.013_bib23","doi-asserted-by":"crossref","first-page":"1649","DOI":"10.1038\/npp.2015.10","article-title":"Effect of parasympathetic stimulation on brain activity during appraisal of fearful expressions","volume":"40","author":"Makovac","year":"2015","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.biopsych.2015.10.013_bib24","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.neubiorev.2008.08.004","article-title":"Claude Bernard and the heart-brain connection: Further elaboration of a model of neurovisceral integration","volume":"33","author":"Thayer","year":"2009","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.biopsych.2015.10.013_bib25","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.neubiorev.2008.08.004","article-title":"A meta-analysis of heart rate variability and neuroimaging studies: Implications for heart rate variability as a marker of stress and health","volume":"33","author":"Thayer","year":"2009","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.biopsych.2015.10.013_bib26","first-page":"261","article-title":"Resting heart rate variability predicts self-reported difficulties in emotion regulation: A focus on different facets of emotion regulation","volume":"10","author":"Williams","year":"2015","journal-title":"Front Psychol"},{"key":"10.1016\/j.biopsych.2015.10.013_bib27","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.biopsycho.2013.05.003","article-title":"Flexibility as the key for somatic health: From mind wandering to perseverative cognition","volume":"94","author":"Ottaviani","year":"2013","journal-title":"Biol Psychol"},{"key":"10.1016\/j.biopsych.2015.10.013_bib28","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1016\/j.biopsycho.2015.02.011","article-title":"Cognitive rigidity is mirrored by autonomic inflexibility in daily life perseverative cognition","volume":"107","author":"Ottaviani","year":"2015","journal-title":"Biol Psychol"},{"key":"10.1016\/j.biopsych.2015.10.013_bib29","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.beth.2009.03.001","article-title":"A taxometric investigation of the latent structure of worry: Dimensionality and associations with depression, anxiety, and stress","volume":"41","author":"Olatunji","year":"2010","journal-title":"Behav Ther"},{"key":"10.1016\/j.biopsych.2015.10.013_bib30","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1023\/A:1023914416469","article-title":"Negative cognitive styles and stress-reactive rumination interact to predict depression: A prospective study","volume":"27","author":"Robinson","year":"2003","journal-title":"Cognit Ther"},{"key":"10.1016\/j.biopsych.2015.10.013_bib31","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1037\/0022-3514.61.1.115","article-title":"A prospective study of depression and posttraumatic stress symptoms after a natural disaster: The 1989 Loma Prieta earthquake","volume":"61","author":"Nolen-Hoeksema","year":"1991","journal-title":"J Pers Soc Psychol"},{"key":"10.1016\/j.biopsych.2015.10.013_bib32","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/0005-7967(90)90135-6","article-title":"Development and validation of the Penn State Worry Questionnaire","volume":"28","author":"Meyer","year":"1990","journal-title":"Behav Res Ther"},{"key":"10.1016\/j.biopsych.2015.10.013_bib33","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1161\/01.CIR.93.5.1043","article-title":"Heart rate variability: Standards of measurement, physiological interpretation, and clinical use","volume":"93","year":"1996","journal-title":"Circulation"},{"key":"10.1016\/j.biopsych.2015.10.013_bib34","doi-asserted-by":"crossref","first-page":"e70468","DOI":"10.1371\/journal.pone.0070468","article-title":"Reduced heart rate variability in social anxiety disorder: Associations with gender and symptom severity","volume":"8","author":"Alvares","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.biopsych.2015.10.013_bib35","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.jdiacomp.2012.05.001","article-title":"Evaluating reliability of ultra-short ECG indices of heart rate variability in diabetes mellitus patients","volume":"26","author":"Nussinovitch","year":"2012","journal-title":"J Diabetes Complications"},{"key":"10.1016\/j.biopsych.2015.10.013_bib36","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1111\/j.1469-8986.2006.00490.x","article-title":"Comparison of time and frequency domain measures of RSA in ambulatory recordings","volume":"44","author":"Goedhart","year":"2007","journal-title":"Psychophysiology"},{"key":"10.1016\/j.biopsych.2015.10.013_bib37","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1046\/j.1365-2281.2001.00337.x","article-title":"Time domain, geometrical and frequency domain analysis of cardiac vagal outflow: Effects of various respiratory patterns","volume":"21","author":"Penttil\u00e4","year":"2001","journal-title":"Clin Physiol"},{"key":"10.1016\/j.biopsych.2015.10.013_bib38","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1089\/brain.2012.0080","article-title":"Trouble at rest: how correlation patterns and group differences become distorted after global signal regression","volume":"2","author":"Saad","year":"2012","journal-title":"Brain Connect"},{"key":"10.1016\/j.biopsych.2015.10.013_bib39","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1006\/nimg.2001.0978","article-title":"Automated anatomical labeling of activations in SPM using a macroscopic anatomical parcellation of the MNI MRI single-subject brain","volume":"15","author":"Tzourio-Mazoyer","year":"2002","journal-title":"Neuroimage"},{"key":"10.1016\/j.biopsych.2015.10.013_bib40","doi-asserted-by":"crossref","first-page":"e114227","DOI":"10.1371\/journal.pone.0114227","article-title":"When structure affects function\u2014the need for partial volume effect correction in functional and resting state magnetic resonance imaging studies","volume":"9","author":"Dukart","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.biopsych.2015.10.013_bib41","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.1093\/cercor\/bhq237","article-title":"Anxiety dissociates dorsal and ventral medial prefrontal cortex functional connectivity with the amygdala at rest","volume":"21","author":"Kim","year":"2011","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.biopsych.2015.10.013_bib42","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1002\/da.22014","article-title":"Aberrant amygdala-frontal cortex connectivity during perception of fearful faces and at rest in generalized social anxiety disorder","volume":"30","author":"Prater","year":"2013","journal-title":"Depress Anxiety"},{"key":"10.1016\/j.biopsych.2015.10.013_bib43","doi-asserted-by":"crossref","first-page":"e15238","DOI":"10.1371\/journal.pone.0015238","article-title":"Altered effective connectivity network of the amygdala in social anxiety disorder: A resting-state FMRI study","volume":"5","author":"Liao","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.biopsych.2015.10.013_bib44","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/j.neuroimage.2011.02.064","article-title":"Reduced resting-state functional connectivity between amygdala and orbitofrontal cortex in social anxiety disorder","volume":"56","author":"Hahn","year":"2011","journal-title":"Neuroimage"},{"key":"10.1016\/j.biopsych.2015.10.013_bib45","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1016\/j.neuroimage.2008.11.030","article-title":"Functional connectivity of the human amygdala using resting state fMRI","volume":"45","author":"Roy","year":"2009","journal-title":"Neuroimage"},{"key":"10.1016\/j.biopsych.2015.10.013_bib46","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1017\/S0033291709005649","article-title":"Neural correlates of worry in generalized anxiety disorder and in normal controls: A functional MRI study","volume":"40","author":"Paulesu","year":"2010","journal-title":"Psychol Med"},{"key":"10.1016\/j.biopsych.2015.10.013_bib47","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1001\/archpsyc.64.1.97","article-title":"Abnormal attention modulation of fear circuit function in pediatric generalized anxiety disorder","volume":"64","author":"McClure","year":"2007","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.biopsych.2015.10.013_bib48","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1093\/cercor\/bht248","article-title":"Unraveling the anxious mind: Anxiety, worry, and frontal engagement in sustained attention versus off-task processing","volume":"25","author":"Forster","year":"2015","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.biopsych.2015.10.013_bib49","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.brainresrev.2004.02.004","article-title":"Lateralization of amygdala activation: A systematic review of functional neuroimaging studies","volume":"45","author":"Baas","year":"2004","journal-title":"Brain Res Brain Res Rev"},{"key":"10.1016\/j.biopsych.2015.10.013_bib50","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1001\/archpsyc.65.10.1176","article-title":"Neural response to self- and other referential praise and criticism in generalized social phobia","volume":"65","author":"Blair","year":"2008","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.biopsych.2015.10.013_bib51","doi-asserted-by":"crossref","first-page":"963","DOI":"10.1016\/j.neuroimage.2009.08.023","article-title":"Neuroticism modulates amygdala-prefrontal connectivity in response to negative emotional facial expressions","volume":"49","author":"Cremers","year":"2010","journal-title":"Neuroimage"},{"key":"10.1016\/j.biopsych.2015.10.013_bib52","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1016\/j.neuroimage.2009.05.091","article-title":"High-frequency heart rate variability and cortico-striatal activity in men and women with social phobia","volume":"47","author":"Ahs","year":"2009","journal-title":"Neuroimage"},{"key":"10.1016\/j.biopsych.2015.10.013_bib53","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.neuroimage.2004.10.013","article-title":"Activity in the human brain predicting differential heart rate responses to emotional facial expressions","volume":"24","author":"Critchley","year":"2005","journal-title":"Neuroimage"},{"key":"10.1016\/j.biopsych.2015.10.013_bib54","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/j.neuroimage.2008.07.056","article-title":"Neural correlates of heart rate variability during emotion","volume":"44","author":"Lane","year":"2009","journal-title":"Neuroimage"},{"key":"10.1016\/j.biopsych.2015.10.013_bib55","doi-asserted-by":"crossref","first-page":"8161","DOI":"10.1523\/JNEUROSCI.1554-07.2007","article-title":"The role of the dorsal striatum in reward and decision-making","volume":"27","author":"Balleine","year":"2007","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2015.10.013_bib56","doi-asserted-by":"crossref","first-page":"2120","DOI":"10.1016\/j.neuropsychologia.2013.07.007","article-title":"The role of the amygdala and the basal ganglia in visual processing of central vs. peripheral emotional content","volume":"51","author":"Almeida","year":"2013","journal-title":"Neuropsychologia"},{"key":"10.1016\/j.biopsych.2015.10.013_bib57","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1016\/j.biopsycho.2013.06.009","article-title":"Heart rate variability and its neural correlates during emotional face processing in social anxiety disorder","volume":"94","author":"Gaebler","year":"2013","journal-title":"Biol Psychol"},{"key":"10.1016\/j.biopsych.2015.10.013_bib58","series-title":"Neuropsychopharmacology: The Fourth Generation of Progress","first-page":"1287","article-title":"Neuroimaging studies of human anxiety disorders: Cutting paths of knowledge through the field of neurotic phenomena","author":"Baxter","year":"1995"},{"key":"10.1016\/j.biopsych.2015.10.013_bib59","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1176\/appi.ajp.2014.14040525","article-title":"Functional neuroimaging of avoidance habits in obsessive-compulsive disorder","volume":"172","author":"Gillan","year":"2015","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.biopsych.2015.10.013_bib60","doi-asserted-by":"crossref","DOI":"10.2190\/PM.41.4.f","article-title":"Anxiety disorders, hypertension, and cardiovascular risk: A review","volume":"41","author":"Player","year":"2011","journal-title":"Int J Psychiatry Med"}],"container-title":["Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322315008604?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322315008604?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,7,14]],"date-time":"2018-07-14T01:18:44Z","timestamp":1531531124000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006322315008604"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":60,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2016,11]]}},"alternative-id":["S0006322315008604"],"URL":"https:\/\/doi.org\/10.1016\/j.biopsych.2015.10.013","relation":{},"ISSN":["0006-3223"],"issn-type":[{"value":"0006-3223","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]}}}