{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T02:34:26Z","timestamp":1791686066901,"version":"4.3.4"},"reference-count":34,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,6,1]],"date-time":"2022-06-01T00:00:00Z","timestamp":1654041600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T00:00:00Z","timestamp":1629331200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100006697","name":"Maa- ja Mets\u00e4talousministeri\u00d6","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006697","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["016.168.313"],"award-info":[{"award-number":["016.168.313"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["biologicalpsychiatryjournal.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biological Psychiatry"],"published-print":{"date-parts":[[2022,6]]},"DOI":"10.1016\/j.biopsych.2021.08.008","type":"journal-article","created":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T11:03:51Z","timestamp":1629371031000},"page":"1029-1038","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Extinction of Cocaine Memory Depends on a Feed-Forward Inhibition Circuit Within the Medial Prefrontal Cortex"],"prefix":"10.1016","volume":"91","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7799-1784","authenticated-orcid":false,"given":"Esther","family":"Visser","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariana R.","family":"Matos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miodrag M.","family":"Mitri\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7565-4418","authenticated-orcid":false,"given":"Ioannis","family":"Kramvis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rolinka J.","family":"van der Loo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huibert D.","family":"Mansvelder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"August B.","family":"Smit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michel C.","family":"van den Oever","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopsych.2021.08.008_bib1","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1001\/archpsyc.1973.01750350005001","article-title":"Dynamics of drug dependence. Implications of a conditioning theory for research and treatment","volume":"28","author":"Wikler","year":"1973","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.biopsych.2021.08.008_bib2","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1101\/lm.1041309","article-title":"Extinction circuits for fear and addiction overlap in prefrontal cortex","volume":"16","author":"Peters","year":"2009","journal-title":"Learn Mem"},{"key":"10.1016\/j.biopsych.2021.08.008_bib3","doi-asserted-by":"crossref","first-page":"92","DOI":"10.2174\/1874941001003020092","article-title":"Progress in cue exposure therapy for the treatment of addictive disorders: A review update","volume":"3","author":"Martin","year":"2010","journal-title":"Open Addict J"},{"key":"10.1016\/j.biopsych.2021.08.008_bib4","doi-asserted-by":"crossref","first-page":"652","DOI":"10.1038\/nrn3119","article-title":"Dysfunction of the prefrontal cortex in addiction: Neuroimaging findings and clinical implications","volume":"12","author":"Goldstein","year":"2011","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.biopsych.2021.08.008_bib5","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1016\/j.neubiorev.2009.11.016","article-title":"Prefrontal cortex plasticity mechanisms in drug seeking and relapse","volume":"35","author":"Van den Oever","year":"2010","journal-title":"Neurosci Biobehav Rev"},{"key":"10.1016\/j.biopsych.2021.08.008_bib6","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.brainres.2014.12.024","article-title":"Differential roles of medial prefrontal subregions in the regulation of drug seeking","volume":"1628","author":"Moorman","year":"2015","journal-title":"Brain Res"},{"key":"10.1016\/j.biopsych.2021.08.008_bib7","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1007\/s00213-013-3120-y","article-title":"The reinstatement model of drug relapse: Recent neurobiological findings, emerging research topics, and translational research","volume":"229","author":"Bossert","year":"2013","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.biopsych.2021.08.008_bib8","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/s002130000569","article-title":"Conditioned place preference: What does it add to our preclinical understanding of drug reward?","volume":"153","author":"Bardo","year":"2000","journal-title":"Psychopharmacology"},{"key":"10.1016\/j.biopsych.2021.08.008_bib9","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1016\/j.neuron.2014.08.023","article-title":"Bidirectional modulation of incubation of cocaine craving by silent synapse-based remodeling of prefrontal cortex to accumbens projections","volume":"83","author":"Ma","year":"2014","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2021.08.008_bib10","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1007\/s00429-015-0997-8","article-title":"Optogenetic inhibition of cortical afferents in the nucleus accumbens simultaneously prevents cue-induced transient synaptic potentiation and cocaine-seeking behavior","volume":"221","author":"Stefanik","year":"2016","journal-title":"Brain Struct Funct"},{"issue":"suppl 1","key":"10.1016\/j.biopsych.2021.08.008_bib11","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1016\/j.neuropharm.2008.04.022","article-title":"Role of ventral medial prefrontal cortex in incubation of cocaine craving","volume":"56","author":"Koya","year":"2009","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.biopsych.2021.08.008_bib12","doi-asserted-by":"crossref","first-page":"7394","DOI":"10.1523\/JNEUROSCI.0918-19.2019","article-title":"Separate vmPFC ensembles control cocaine self-administration versus extinction in rats","volume":"39","author":"Warren","year":"2019","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.biopsych.2021.08.008_bib13","doi-asserted-by":"crossref","first-page":"10174","DOI":"10.1523\/JNEUROSCI.0773-16.2016","article-title":"Chemogenetic activation of an extinction neural circuit reduces cue-induced reinstatement of cocaine seeking","volume":"36","author":"Augur","year":"2016","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.biopsych.2021.08.008_bib14","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1038\/s41593-018-0137-x","article-title":"Excitatory connections between the prelimbic and infralimbic medial prefrontal cortex show a role for the prelimbic cortex in fear extinction","volume":"21","author":"Marek","year":"2018","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.biopsych.2021.08.008_bib15","doi-asserted-by":"crossref","first-page":"e2725","DOI":"10.1371\/journal.pone.0002725","article-title":"Prelimbic and infralimbic prefrontal cortex interact during fast network oscillations","volume":"3","author":"van Aerde","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.biopsych.2021.08.008_bib16","doi-asserted-by":"crossref","first-page":"2727","DOI":"10.1038\/s41467-018-05318-x","article-title":"Infralimbic cortex is required for learning alternatives to prelimbic promoted associations through reciprocal connectivity","volume":"9","author":"Mukherjee","year":"2018","journal-title":"Nat Commun"},{"key":"10.1016\/j.biopsych.2021.08.008_bib17","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1007\/s00429-007-0150-4","article-title":"Anatomical analysis of afferent projections to the medial prefrontal cortex in the rat","volume":"212","author":"Hoover","year":"2007","journal-title":"Brain Struct Funct"},{"key":"10.1016\/j.biopsych.2021.08.008_bib18","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1016\/j.neuron.2016.09.021","article-title":"A\u00a0designer AAV variant permits efficient retrograde access to projection neurons","volume":"92","author":"Tervo","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2021.08.008_bib19","doi-asserted-by":"crossref","first-page":"18225","DOI":"10.1523\/JNEUROSCI.2412-13.2013","article-title":"Ventromedial prefrontal cortex pyramidal cells have a temporal dynamic role in recall and extinction of cocaine-associated memory","volume":"33","author":"Van den Oever","year":"2013","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.biopsych.2021.08.008_bib20","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1186\/1756-6606-5-36","article-title":"Modulation of medial prefrontal cortical activity using in\u00a0vivo recordings and optogenetics","volume":"5","author":"Ji","year":"2012","journal-title":"Mol Brain"},{"key":"10.1016\/j.biopsych.2021.08.008_bib21","doi-asserted-by":"crossref","first-page":"3699","DOI":"10.1523\/JNEUROSCI.0235-13.2014","article-title":"Activation of prefrontal cortical parvalbumin interneurons facilitates extinction of reward-seeking behavior","volume":"34","author":"Sparta","year":"2014","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.biopsych.2021.08.008_bib22","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1038\/nature12755","article-title":"Prefrontal parvalbumin interneurons shape neuronal activity to drive fear expression","volume":"505","author":"Courtin","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.biopsych.2021.08.008_bib23","doi-asserted-by":"crossref","first-page":"1491","DOI":"10.1016\/j.neuron.2013.09.025","article-title":"Synaptic encoding of fear extinction in mPFC-amygdala circuits","volume":"80","author":"Cho","year":"2013","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2021.08.008_bib24","doi-asserted-by":"crossref","first-page":"6046","DOI":"10.1523\/JNEUROSCI.1045-08.2008","article-title":"Infralimbic prefrontal cortex is responsible for inhibiting cocaine seeking in extinguished rats","volume":"28","author":"Peters","year":"2008","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.biopsych.2021.08.008_bib25","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1101\/lm.1576810","article-title":"The infralimbic cortex regulates the consolidation of extinction after cocaine self-administration","volume":"17","author":"LaLumiere","year":"2010","journal-title":"Learn Mem"},{"key":"10.1016\/j.biopsych.2021.08.008_bib26","doi-asserted-by":"crossref","first-page":"6691","DOI":"10.1523\/JNEUROSCI.0140-16.2016","article-title":"Distinct Fos-expressing neuronal ensembles in the ventromedial prefrontal cortex mediate food reward and extinction memories","volume":"36","author":"Warren","year":"2016","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.biopsych.2021.08.008_bib27","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.21920","article-title":"Distinct memory engrams in the infralimbic cortex of rats control opposing environmental actions on a learned behavior","volume":"5","author":"Suto","year":"2016","journal-title":"Elife"},{"key":"10.1016\/j.biopsych.2021.08.008_bib28","doi-asserted-by":"crossref","first-page":"9472","DOI":"10.1073\/pnas.1507611112","article-title":"Prefrontal neurons encode context-based response execution and inhibition in reward seeking and extinction","volume":"112","author":"Moorman","year":"2015","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biopsych.2021.08.008_bib29","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/j.neulet.2008.08.015","article-title":"Inactivation of the ventromedial prefrontal cortex mimics re-emergence of heroin seeking caused by heroin reconditioning","volume":"444","author":"Ovari","year":"2008","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.biopsych.2021.08.008_bib30","doi-asserted-by":"crossref","first-page":"1972","DOI":"10.1038\/npp.2011.63","article-title":"PKM\u03b6 maintains drug reward and aversion memory in the basolateral amygdala and extinction memory in the infralimbic cortex","volume":"36","author":"He","year":"2011","journal-title":"Neuropsychopharmacol"},{"key":"10.1016\/j.biopsych.2021.08.008_bib31","doi-asserted-by":"crossref","first-page":"1053","DOI":"10.1038\/nn.2165","article-title":"Prefrontal cortex AMPA receptor plasticity is crucial for cue-induced relapse to heroin-seeking","volume":"11","author":"Van den Oever","year":"2008","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.biopsych.2021.08.008_bib32","doi-asserted-by":"crossref","first-page":"2498","DOI":"10.1111\/j.1460-9568.2007.05486.x","article-title":"Lesions of rat infralimbic cortex enhance renewal of extinguished appetitive Pavlovian responding","volume":"25","author":"Rhodes","year":"2007","journal-title":"Eur J Neurosci"},{"key":"10.1016\/j.biopsych.2021.08.008_bib33","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1101\/lm.79704","article-title":"Lesions of rat infralimbic cortex enhance recovery and reinstatement of an appetitive Pavlovian response","volume":"11","author":"Rhodes","year":"2004","journal-title":"Learn Mem"},{"key":"10.1016\/j.biopsych.2021.08.008_bib34","doi-asserted-by":"crossref","first-page":"3723","DOI":"10.1111\/ejn.14754","article-title":"Extinction of cue-evoked food-seeking recruits a GABAergic interneuron ensemble in the dorsal medial prefrontal cortex of mice","volume":"52","author":"Brebner","year":"2020","journal-title":"Eur J Neurosci"}],"container-title":["Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322321015286?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322321015286?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,13]],"date-time":"2025-09-13T15:14:16Z","timestamp":1757776456000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006322321015286"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6]]},"references-count":34,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2022,6]]}},"alternative-id":["S0006322321015286"],"URL":"https:\/\/doi.org\/10.1016\/j.biopsych.2021.08.008","relation":{},"ISSN":["0006-3223"],"issn-type":[{"value":"0006-3223","type":"print"}],"subject":[],"published":{"date-parts":[[2022,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Extinction of Cocaine Memory Depends on a Feed-Forward Inhibition Circuit Within the Medial Prefrontal Cortex","name":"articletitle","label":"Article Title"},{"value":"Biological Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopsych.2021.08.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Society of Biological Psychiatry.","name":"copyright","label":"Copyright"}]}}