{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T16:28:59Z","timestamp":1793636939323,"version":"4.5.1"},"reference-count":64,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,2,1]],"date-time":"2023-02-01T00:00:00Z","timestamp":1675209600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP2013243"],"award-info":[{"award-number":["APP2013243"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1154974"],"award-info":[{"award-number":["APP1154974"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1126724"],"award-info":[{"award-number":["APP1126724"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["biologicalpsychiatryjournal.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biological Psychiatry"],"published-print":{"date-parts":[[2023,2]]},"DOI":"10.1016\/j.biopsych.2022.08.022","type":"journal-article","created":{"date-parts":[[2022,8,31]],"date-time":"2022-08-31T03:04:19Z","timestamp":1661915059000},"page":"309-321","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":32,"title":["Identification of a Stress-Sensitive Anorexigenic Neurocircuit From Medial Prefrontal Cortex to Lateral Hypothalamus"],"prefix":"10.1016","volume":"93","author":[{"given":"Rachel E.","family":"Clarke","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katharina","family":"Voigt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Reichenbach","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romana","family":"Stark","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Urvi","family":"Bharania","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harry","family":"Dempsey","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarah H.","family":"Lockie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mathieu","family":"Mequinion","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Moyra","family":"Lemus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bowen","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felicia","family":"Reed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sasha","family":"Rawlinson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Nunez-Iglesias","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claire J.","family":"Foldi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexxai V.","family":"Kravitz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Verdejo-Garcia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9097-7944","authenticated-orcid":false,"given":"Zane B.","family":"Andrews","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopsych.2022.08.022_bib1","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1038\/nature14177","article-title":"Genetic studies of body mass index yield new insights for obesity biology","volume":"518","author":"Locke","year":"2015","journal-title":"Nature"},{"issue":"suppl 7","key":"10.1016\/j.biopsych.2022.08.022_bib2","doi-asserted-by":"crossref","first-page":"S55","DOI":"10.1038\/ijo.2008.239","article-title":"Human obesity as a heritable disorder of the central control of energy balance","volume":"32","author":"O\u2019Rahilly","year":"2008","journal-title":"Int J Obes (Lond)"},{"key":"10.1016\/j.biopsych.2022.08.022_bib3","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1016\/j.neuron.2017.06.014","article-title":"Toward a wiring diagram understanding of appetite control","volume":"95","author":"Andermann","year":"2017","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2022.08.022_bib4","doi-asserted-by":"crossref","first-page":"159","DOI":"10.1111\/obr.12354","article-title":"Food cue reactivity and craving predict eating and weight gain: A meta-analytic review","volume":"17","author":"Boswell","year":"2016","journal-title":"Obes Rev"},{"key":"10.1016\/j.biopsych.2022.08.022_bib5","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.physbeh.2012.01.007","article-title":"Cognitive and neuronal systems underlying obesity","volume":"106","author":"Kanoski","year":"2012","journal-title":"Physiol Behav"},{"key":"10.1016\/j.biopsych.2022.08.022_bib6","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1038\/ijo.2017.237","article-title":"Brain substrates of unhealthy versus healthy food choices: Influence of homeostatic status and body mass index","volume":"42","author":"Harding","year":"2018","journal-title":"Int J Obes (Lond)"},{"key":"10.1016\/j.biopsych.2022.08.022_bib7","doi-asserted-by":"crossref","first-page":"646","DOI":"10.1126\/science.1168450","article-title":"Self-control in decision-making involves modulation of the vmPFC valuation system","volume":"324","author":"Hare","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.biopsych.2022.08.022_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0060393","article-title":"Increased prefrontal and parahippocampal activation with reduced dorsolateral prefrontal and insular cortex activation to food images in obesity: A meta-analysis of fMRI studies","volume":"8","author":"Brooks","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.biopsych.2022.08.022_bib9","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.appet.2013.12.017","article-title":"Influence of feeding state on neurofunctional differences between individuals who are obese and normal weight: A meta-analysis of neuroimaging studies","volume":"75","author":"Kennedy","year":"2014","journal-title":"Appetite"},{"key":"10.1016\/j.biopsych.2022.08.022_bib10","doi-asserted-by":"crossref","first-page":"636","DOI":"10.1016\/j.neuroimage.2008.02.031","article-title":"Widespread reward-system activation in obese women in response to pictures of high-calorie foods","volume":"41","author":"Stoeckel","year":"2008","journal-title":"Neuroimage"},{"key":"10.1016\/j.biopsych.2022.08.022_bib11","doi-asserted-by":"crossref","first-page":"1238","DOI":"10.1176\/appi.ajp.161.7.1238","article-title":"Medial prefrontal cortex activity associated with symptom provocation in eating disorders","volume":"161","author":"Uher","year":"2004","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.biopsych.2022.08.022_bib12","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.conb.2016.05.003","article-title":"From regions to connections and networks: New bridges between brain and behavior","volume":"40","author":"Mi\u0161i\u0107","year":"2016","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.biopsych.2022.08.022_bib13","doi-asserted-by":"crossref","first-page":"9951","DOI":"10.1038\/s41598-017-09874-y","article-title":"Altered cross-talk between the hypothalamus and non-homeostatic regions linked to obesity and difficulty to lose weight","volume":"7","author":"Contreras-Rodr\u00edguez","year":"2017","journal-title":"Sci Rep"},{"key":"10.1016\/j.biopsych.2022.08.022_bib14","doi-asserted-by":"crossref","first-page":"6088","DOI":"10.1002\/hbm.22607","article-title":"Resting-state functional connectivity of the human hypothalamus","volume":"35","author":"Kullmann","year":"2014","journal-title":"Hum Brain Mapp"},{"key":"10.1016\/j.biopsych.2022.08.022_bib15","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1016\/j.cell.2014.12.026","article-title":"Visualizing hypothalamic network dynamics for appetitive and consummatory behaviors","volume":"160","author":"Jennings","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.biopsych.2022.08.022_bib16","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1038\/nn.3423","article-title":"Opportunities and limitations of intrinsic functional connectivity MRI","volume":"16","author":"Buckner","year":"2013","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.biopsych.2022.08.022_bib17","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/0361-9230(81)90101-5","article-title":"Afferent connections to the lateral hypothalamus: A horseradish-peroxidase study in the rat","volume":"7","author":"Barone","year":"1981","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.biopsych.2022.08.022_bib18","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/j.brainresrev.2010.02.002","article-title":"Distinct patterns of neuronal inputs and outputs of the juxtaparaventricular and suprafornical regions of the lateral hypothalamic area in the male rat","volume":"64","author":"Hahn","year":"2010","journal-title":"Brain Res Rev"},{"key":"10.1016\/j.biopsych.2022.08.022_bib19","doi-asserted-by":"crossref","first-page":"4065","DOI":"10.1523\/JNEUROSCI.3234-17.2018","article-title":"Task division within the prefrontal cortex: Distinct neuron populations selectively control different aspects of aggressive behavior via the hypothalamus","volume":"38","author":"Biro","year":"2018","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.biopsych.2022.08.022_bib20","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.brainres.2018.09.024","article-title":"Dopamine D1 receptor in the medial prefrontal cortex mediates anxiety-like behaviors induced by blocking glutamatergic activity of the ventral hippocampus in rats","volume":"1704","author":"Liu","year":"2019","journal-title":"Brain Res"},{"key":"10.1016\/j.biopsych.2022.08.022_bib21","doi-asserted-by":"crossref","first-page":"667","DOI":"10.1038\/s41586-022-04507-5","article-title":"Cortical ensembles orchestrate social competition through hypothalamic outputs","volume":"603","author":"Padilla-Coreano","year":"2022","journal-title":"Nature"},{"key":"10.1016\/j.biopsych.2022.08.022_bib22","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.66173.sa2","article-title":"Feeding Experimentation Device version 3 (FED3): An open-source home-cage compatible device for measuring food intake and operant behavior","author":"Matikainen-Ankney","year":"2021","journal-title":"Elife"},{"key":"10.1016\/j.biopsych.2022.08.022_bib23","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1016\/j.neuroimage.2006.08.035","article-title":"Variational free energy and the Laplace approximation","volume":"34","author":"Friston","year":"2007","journal-title":"Neuroimage"},{"key":"10.1016\/j.biopsych.2022.08.022_bib24","doi-asserted-by":"crossref","first-page":"1013","DOI":"10.1016\/j.cell.2017.07.020","article-title":"Molecular and circuit-dynamical identification of top-down neural mechanisms for restraint of reward seeking","volume":"170","author":"Kim","year":"2017","journal-title":"Cell"},{"key":"10.1016\/j.biopsych.2022.08.022_bib25","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0315-18.2018","article-title":"What, if anything, is rodent prefrontal cortex?","volume":"5","author":"Laubach","year":"2018","journal-title":"eNeuro"},{"key":"10.1016\/j.biopsych.2022.08.022_bib26","doi-asserted-by":"crossref","first-page":"640","DOI":"10.1038\/s41467-020-14281-5","article-title":"The anterior insular cortex unilaterally controls feeding in response to aversive visceral stimuli in mice","volume":"11","author":"Wu","year":"2020","journal-title":"Nat Commun"},{"key":"10.1016\/j.biopsych.2022.08.022_bib27","doi-asserted-by":"crossref","first-page":"398","DOI":"10.1038\/s41593-020-0591-0","article-title":"Paraventricular nucleus CRH neurons encode stress controllability and regulate defensive behavior selection","volume":"23","author":"Daviu","year":"2020","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.biopsych.2022.08.022_bib28","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1016\/S0006-3223(02)01827-9","article-title":"Validation of a simple, ethologically relevant paradigm for assessing anxiety in mice","volume":"54","author":"Merali","year":"2003","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2022.08.022_bib29","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.70271","article-title":"Assessing the effects of stress on feeding behaviors in laboratory mice","volume":"11","author":"Francois","year":"2022","journal-title":"Elife"},{"key":"10.1016\/j.biopsych.2022.08.022_bib30","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1515\/REVNEURO.2006.17.1-2.111","article-title":"Rearing on hind legs, environmental novelty, and the hippocampal formation","volume":"17","author":"Lever","year":"2006","journal-title":"Rev Neurosci"},{"key":"10.1016\/j.biopsych.2022.08.022_bib31","doi-asserted-by":"crossref","first-page":"999","DOI":"10.1016\/j.cell.2018.06.021","article-title":"Molecular architecture of the mouse nervous system","volume":"174","author":"Zeisel","year":"2018","journal-title":"Cell"},{"key":"10.1016\/j.biopsych.2022.08.022_bib32","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1016\/j.neuron.2016.12.031","article-title":"Flexible near-field wireless optoelectronics as subdermal implants for broad applications in optogenetics","volume":"93","author":"Shin","year":"2017","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2022.08.022_bib33","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1038\/ijo.2009.56","article-title":"Activation in brain energy regulation and reward centers by food cues varies with choice of visual stimulus","volume":"33","author":"Schur","year":"2009","journal-title":"Int J Obes (Lond)"},{"key":"10.1016\/j.biopsych.2022.08.022_bib34","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1038\/nn.3625","article-title":"Medial prefrontal D1 dopamine neurons control food intake","volume":"17","author":"Land","year":"2014","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.biopsych.2022.08.022_bib35","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1038\/nature21376","article-title":"Prefrontal cortex output circuits guide reward seeking through divergent cue encoding","volume":"543","author":"Otis","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.biopsych.2022.08.022_bib36","doi-asserted-by":"crossref","first-page":"17278","DOI":"10.1073\/pnas.2000523117","article-title":"Inhibition of impulsive action by projection-defined prefrontal pyramidal neurons","volume":"117","author":"Li","year":"2020","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biopsych.2022.08.022_bib37","doi-asserted-by":"crossref","first-page":"69","DOI":"10.3389\/fncom.2014.00069","article-title":"A\u00a0general role for medial prefrontal cortex in event prediction","volume":"8","author":"Alexander","year":"2014","journal-title":"Front Comput Neurosci"},{"key":"10.1016\/j.biopsych.2022.08.022_bib38","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1186\/2045-5380-1-2","article-title":"Medial prefrontal cortex serotonin 1A and 2-A receptor binding interacts to predict threat-related amygdala reactivity","volume":"1","author":"Fisher","year":"2011","journal-title":"Biol Mood Anxiety Disord"},{"key":"10.1016\/j.biopsych.2022.08.022_bib39","doi-asserted-by":"crossref","first-page":"1715","DOI":"10.1038\/npp.2017.56","article-title":"Bidirectional control of anxiety-related behaviors in mice: Role of inputs arising from the ventral hippocampus to the lateral septum and medial prefrontal cortex","volume":"42","author":"Parfitt","year":"2017","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.biopsych.2022.08.022_bib40","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0166-4328(01)00204-2","article-title":"Neurons in rat medial prefrontal cortex show anticipatory rate changes to predictable differential rewards in a spatial memory task","volume":"123","author":"Pratt","year":"2001","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.biopsych.2022.08.022_bib41","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1111\/jne.12272","article-title":"The medial prefrontal cortex: Coordinator of autonomic, neuroendocrine and behavioural responses to stress","volume":"27","author":"McKlveen","year":"2015","journal-title":"J\u00a0Neuroendocrinol"},{"key":"10.1016\/j.biopsych.2022.08.022_bib42","doi-asserted-by":"crossref","first-page":"12967","DOI":"10.1523\/JNEUROSCI.4297-06.2006","article-title":"Regional differentiation of the medial prefrontal cortex in regulating adaptive responses to acute emotional stress","volume":"26","author":"Radley","year":"2006","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.biopsych.2022.08.022_bib43","doi-asserted-by":"crossref","first-page":"743","DOI":"10.1016\/j.biopsych.2016.03.2106","article-title":"Prefrontal cortex corticotropin-releasing factor Receptor 1 conveys acute stress-induced executive dysfunction","volume":"80","author":"Uribe-Mari\u00f1o","year":"2016","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2022.08.022_bib44","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1016\/j.tins.2017.03.002","article-title":"The role of mental maps in decision-making","volume":"40","author":"Kaplan","year":"2017","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.biopsych.2022.08.022_bib45","doi-asserted-by":"crossref","first-page":"7526","DOI":"10.1523\/JNEUROSCI.0386-09.2009","article-title":"Dynamic encoding of responses and outcomes by neurons in medial prefrontal cortex","volume":"29","author":"Luk","year":"2009","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.biopsych.2022.08.022_bib46","doi-asserted-by":"crossref","first-page":"1981","DOI":"10.1152\/jn.00793.2018","article-title":"Disrupting the medial prefrontal cortex alters hippocampal sequences during deliberative decision making","volume":"121","author":"Schmidt","year":"2019","journal-title":"J\u00a0Neurophysiol"},{"key":"10.1016\/j.biopsych.2022.08.022_bib47","doi-asserted-by":"crossref","first-page":"5696","DOI":"10.1038\/s41467-019-13639-8","article-title":"Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity","volume":"10","author":"Kim","year":"2019","journal-title":"Nat Commun"},{"key":"10.1016\/j.biopsych.2022.08.022_bib48","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.cell.2015.01.033","article-title":"Sensory detection of food rapidly modulates arcuate feeding circuits","volume":"160","author":"Chen","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.biopsych.2022.08.022_bib49","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.72668","article-title":"Metabolic sensing in AgRP neurons integrates homeostatic state with dopamine signalling in the striatum","volume":"11","author":"Reichenbach","year":"2022","journal-title":"Elife"},{"key":"10.1016\/j.biopsych.2022.08.022_bib50","doi-asserted-by":"crossref","first-page":"252","DOI":"10.3389\/fnbeh.2019.00252","article-title":"Reduced medial prefrontal control of palatable food consumption is associated with binge eating proneness in female rats","volume":"13","author":"Sinclair","year":"2019","journal-title":"Front Behav Neurosci"},{"key":"10.1016\/j.biopsych.2022.08.022_bib51","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.neulet.2017.08.019","article-title":"A\u00a0standardization of the Novelty-Suppressed Feeding Test protocol in rats","volume":"658","author":"Blasco-Serra","year":"2017","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.biopsych.2022.08.022_bib52","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1038\/nature12024","article-title":"Rescuing cocaine-induced prefrontal cortex hypoactivity prevents compulsive cocaine seeking","volume":"496","author":"Chen","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.biopsych.2022.08.022_bib53","doi-asserted-by":"crossref","first-page":"aac9698","DOI":"10.1126\/science.aac9698","article-title":"Prefrontal cortical regulation of brainwide circuit dynamics and reward-related behavior","volume":"351","author":"Ferenczi","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.biopsych.2022.08.022_bib54","doi-asserted-by":"crossref","first-page":"875","DOI":"10.1037\/a0016330","article-title":"The rat prelimbic cortex mediates inhibitory response control but not the consolidation of instrumental learning","volume":"123","author":"Jonkman","year":"2009","journal-title":"Behav Neurosci"},{"key":"10.1016\/j.biopsych.2022.08.022_bib55","doi-asserted-by":"crossref","first-page":"10750","DOI":"10.1523\/JNEUROSCI.0684-15.2015","article-title":"Losing control: Excessive alcohol seeking after selective inactivation of cue-responsive neurons in the infralimbic cortex","volume":"35","author":"Pfarr","year":"2015","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.biopsych.2022.08.022_bib56","doi-asserted-by":"crossref","first-page":"4982","DOI":"10.1523\/JNEUROSCI.0005-12.2012","article-title":"Role of projections from ventral medial prefrontal cortex to nucleus accumbens shell in context-induced reinstatement of heroin seeking","volume":"32","author":"Bossert","year":"2012","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.biopsych.2022.08.022_bib57","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.1523\/JNEUROSCI.4177-03.2004","article-title":"Limbic and motor circuitry underlying footshock-induced reinstatement of cocaine-seeking behavior","volume":"24","author":"McFarland","year":"2004","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.biopsych.2022.08.022_bib58","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.1016\/S0140-6736(05)60529-6","article-title":"Functional anatomy of calorie fear in anorexia nervosa","volume":"352","author":"Ellison","year":"1998","journal-title":"Lancet"},{"key":"10.1016\/j.biopsych.2022.08.022_bib59","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1038\/s41593-019-0374-7","article-title":"Distinct cortical-amygdala projections drive reward value encoding and retrieval","volume":"22","author":"Malvaez","year":"2019","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.biopsych.2022.08.022_bib60","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1523\/JNEUROSCI.1202-15.2016","article-title":"Lateral hypothalamic area glutamatergic neurons and their projections to the lateral habenula regulate feeding and reward","volume":"36","author":"Stamatakis","year":"2016","journal-title":"J\u00a0Neurosci"},{"key":"10.1016\/j.biopsych.2022.08.022_bib61","doi-asserted-by":"crossref","first-page":"3797","DOI":"10.1016\/j.cub.2021.06.048","article-title":"Hypothalamic control of interoceptive hunger","volume":"31","author":"Siemian","year":"2021","journal-title":"Curr Biol"},{"key":"10.1016\/j.biopsych.2022.08.022_bib62","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1038\/s41586-021-03729-3","article-title":"Food cue regulation of AGRP hunger neurons guides learning","volume":"595","author":"Berrios","year":"2021","journal-title":"Nature"},{"key":"10.1016\/j.biopsych.2022.08.022_bib63","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms11395","article-title":"Awake dynamics and brain-wide direct inputs of hypothalamic MCH and orexin networks","volume":"7","author":"Gonz\u00e1lez","year":"2016","journal-title":"Nat Commun"},{"key":"10.1016\/j.biopsych.2022.08.022_bib64","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1016\/j.biopsych.2020.06.022","article-title":"Suppression of corticostriatal circuit activity improves cognitive flexibility and prevents body weight loss in activity-based anorexia in rats","volume":"90","author":"Milton","year":"2021","journal-title":"Biol Psychiatry"}],"container-title":["Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322322015505?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322322015505?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T14:19:07Z","timestamp":1777385947000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006322322015505"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,2]]},"references-count":64,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2023,2]]}},"alternative-id":["S0006322322015505"],"URL":"https:\/\/doi.org\/10.1016\/j.biopsych.2022.08.022","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2021.09.07.459350","asserted-by":"object"}]},"ISSN":["0006-3223"],"issn-type":[{"value":"0006-3223","type":"print"}],"subject":[],"published":{"date-parts":[[2023,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of a Stress-Sensitive Anorexigenic Neurocircuit From Medial Prefrontal Cortex to Lateral Hypothalamus","name":"articletitle","label":"Article Title"},{"value":"Biological Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopsych.2022.08.022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Society of Biological Psychiatry.","name":"copyright","label":"Copyright"}]}}