{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T22:21:25Z","timestamp":1794608485323,"version":"4.9.1"},"reference-count":72,"publisher":"Elsevier BV","issue":"8","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,15]],"date-time":"2025-03-15T00:00:00Z","timestamp":1741996800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100018694","name":"European Commission Marie Sklodowska-Curie Actions","doi-asserted-by":"publisher","award":["FP7-PEOPLE-2013-CIG 618807"],"award-info":[{"award-number":["FP7-PEOPLE-2013-CIG 618807"]}],"id":[{"id":"10.13039\/100018694","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001665","name":"ANR","doi-asserted-by":"publisher","award":["ANR-15-CE16-0005"],"award-info":[{"award-number":["ANR-15-CE16-0005"]}],"id":[{"id":"10.13039\/501100001665","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2018\/14153-7"],"award-info":[{"award-number":["2018\/14153-7"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2019\/17065-4"],"award-info":[{"award-number":["2019\/17065-4"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2021\/07134-9"],"award-info":[{"award-number":["2021\/07134-9"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2021\/12978-1"],"award-info":[{"award-number":["2021\/12978-1"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","award":["2018\/15505-4"],"award-info":[{"award-number":["2018\/15505-4"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100011264","name":"FP7 People: Marie-Curie Actions","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100011264","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000874","name":"NARSAD","doi-asserted-by":"publisher","award":["17566"],"award-info":[{"award-number":["17566"]}],"id":[{"id":"10.13039\/100000874","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100019125","name":"Sorbonne Universit\u00e9","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100019125","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001677","name":"Institut National de la Sant\u00e9 et de la Recherche M\u00e9dicale","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001677","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004794","name":"Centre National de la Recherche Scientifique","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004794","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Humanidades, Ciencias y Tecnolog\u00edas","doi-asserted-by":"publisher","award":["PN2017-4687"],"award-info":[{"award-number":["PN2017-4687"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003141","name":"Consejo Nacional de Humanidades, Ciencias y Tecnolog\u00edas","doi-asserted-by":"publisher","award":["2019 296652"],"award-info":[{"award-number":["2019 296652"]}],"id":[{"id":"10.13039\/501100003141","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["biologicalpsychiatryjournal.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biological Psychiatry"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.biopsych.2025.02.904","type":"journal-article","created":{"date-parts":[[2025,3,18]],"date-time":"2025-03-18T13:13:31Z","timestamp":1742303611000},"page":"612-623","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Astrocytes Control Cocaine-Induced Synaptic Plasticity and Reward Through the Matricellular Protein Hevin"],"prefix":"10.1016","volume":"98","author":[{"given":"Rapha\u00eble","family":"Mongr\u00e9dien","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Augusto","family":"Anesio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gustavo J.D.","family":"Fernandes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew L.","family":"Eagle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steeve","family":"Maldera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuong","family":"Pham","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S\u00e9verine","family":"Robert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernando","family":"Bezerra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ad\u00e8le","family":"Vilette","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paula C.","family":"Bianchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara","family":"Franco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Franck","family":"Louis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carole","family":"Gruszczynski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie-Laure","family":"Ni\u00e9pon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catalina","family":"Betancur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amaia M.","family":"Erdozain","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alfred J.","family":"Robison","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antony A.","family":"Boucard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fabio C.","family":"Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongdong","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicolas","family":"Heck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sophie","family":"Gautron","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8212-751X","authenticated-orcid":false,"given":"Vincent","family":"Vialou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopsych.2025.02.904_bib1","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/j.neuron.2011.01.017","article-title":"Drug-evoked synaptic plasticity in addiction: From molecular changes to circuit remodeling","volume":"69","author":"L\u00fcscher","year":"2011","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2025.02.904_bib2","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1038\/nature10709","article-title":"Reversal of cocaine-evoked synaptic potentiation resets drug-induced adaptive behaviour","volume":"481","author":"Pascoli","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.biopsych.2025.02.904_bib3","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/bs.pbr.2017.07.013","article-title":"Corticostriatal plasticity, neuronal ensembles, and regulation of drug-seeking behavior","volume":"235","author":"Bobadilla","year":"2017","journal-title":"Prog Brain Res"},{"key":"10.1016\/j.biopsych.2025.02.904_bib4","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/j.biopsych.2015.12.022","article-title":"Cocaine self-administration and extinction leads to reduced glial fibrillary acidic protein expression and morphometric features of astrocytes in the nucleus accumbens core","volume":"80","author":"Scofield","year":"2016","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.02.904_bib5","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1016\/j.biopsych.2019.06.026","article-title":"Heroin cue-evoked astrocytic structural plasticity at nucleus accumbens synapses inhibits heroin seeking","volume":"86","author":"Kruyer","year":"2019","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.02.904_bib6","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abo7044","article-title":"Plasticity in astrocyte subpopulations regulates heroin relapse","volume":"8","author":"Kruyer","year":"2022","journal-title":"Sci Adv"},{"key":"10.1016\/j.biopsych.2025.02.904_bib7","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.neuroscience.2012.02.049","article-title":"Differential effects of cocaine access and withdrawal on glutamate type 1 transporter expression in rat nucleus accumbens core and shell","volume":"210","author":"Fischer-Smith","year":"2012","journal-title":"Neuroscience"},{"key":"10.1016\/j.biopsych.2025.02.904_bib8","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1016\/j.neuron.2019.12.026","article-title":"Dopamine-evoked synaptic regulation in the nucleus accumbens requires astrocyte activity","volume":"105","author":"Corkrum","year":"2020","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2025.02.904_bib9","doi-asserted-by":"crossref","first-page":"1995","DOI":"10.1073\/pnas.0609408104","article-title":"mGluR5 stimulates gliotransmission in the nucleus accumbens","volume":"104","author":"D\u2019Ascenzo","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.biopsych.2025.02.904_bib10","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/j.biopsych.2015.02.016","article-title":"Gq-DREADD selectively initiates glial glutamate release and inhibits cue-induced cocaine seeking","volume":"78","author":"Scofield","year":"2015","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.02.904_bib11","article-title":"Cocaine experience induces functional adaptations in astrocytes: Implications for synaptic plasticity in the nucleus accumbens shell","volume":"26","author":"O\u2019Donovan","year":"2021","journal-title":"Addict Biol"},{"key":"10.1016\/j.biopsych.2025.02.904_bib12","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1016\/j.biopsych.2020.08.012","article-title":"Cocaine triggers astrocyte-mediated synaptogenesis","volume":"89","author":"Wang","year":"2021","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.02.904_bib13","doi-asserted-by":"crossref","first-page":"1280","DOI":"10.1016\/j.cell.2019.03.019","article-title":"Hyperactivity with disrupted attention by activation of an astrocyte synaptogenic cue","volume":"177","author":"Nagai","year":"2019","journal-title":"Cell"},{"key":"10.1016\/j.biopsych.2025.02.904_bib14","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1038\/nn.2551","article-title":"DeltaFosB in brain reward circuits mediates resilience to stress and antidepressant responses","volume":"13","author":"Vialou","year":"2010","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.biopsych.2025.02.904_bib15","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1016\/j.neuron.2017.09.056","article-title":"Cell biology of astrocyte-synapse interactions","volume":"96","author":"Allen","year":"2017","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2025.02.904_bib16","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1083\/jcb.130.3.503","article-title":"Diversity of function is inherent in matricellular proteins: An appraisal of thrombospondin 1","volume":"130","author":"Bornstein","year":"1995","journal-title":"J Cell Biol"},{"key":"10.1016\/j.biopsych.2025.02.904_bib17","doi-asserted-by":"crossref","first-page":"E440","DOI":"10.1073\/pnas.1104977108","article-title":"Control of excitatory CNS synaptogenesis by astrocyte-secreted proteins Hevin and SPARC","volume":"108","author":"Kucukdereli","year":"2011","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.biopsych.2025.02.904_bib18","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s11064-006-9226-4","article-title":"Localization of the extracellular matrix protein SC1 to synapses in the adult rat brain","volume":"32","author":"Lively","year":"2007","journal-title":"Neurochem Res"},{"key":"10.1016\/j.biopsych.2025.02.904_bib19","doi-asserted-by":"crossref","first-page":"12524","DOI":"10.1073\/pnas.1902672116","article-title":"Specific factors in blood from young but not old mice directly promote synapse formation and NMDA-receptor recruitment","volume":"116","author":"Gan","year":"2019","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.biopsych.2025.02.904_bib20","doi-asserted-by":"crossref","first-page":"8088","DOI":"10.1523\/JNEUROSCI.0454-20.2020","article-title":"SPARCL1 promotes excitatory but not inhibitory synapse formation and function independent of neurexins and neuroligins","volume":"40","author":"Gan","year":"2020","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2025.02.904_bib21","doi-asserted-by":"crossref","first-page":"5868","DOI":"10.1074\/jbc.M109.070318","article-title":"Processing of the matricellular protein hevin in mouse brain is dependent on ADAMTS4","volume":"285","author":"Weaver","year":"2010","journal-title":"J Biol Chem"},{"key":"10.1016\/j.biopsych.2025.02.904_bib22","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.cell.2015.11.034","article-title":"Astrocytes assemble thalamocortical synapses by bridging NRX1\u03b1 and NL1 via hevin","volume":"164","author":"Singh","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.biopsych.2025.02.904_bib23","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.04047","article-title":"Astrocytes refine cortical connectivity at dendritic spines","volume":"3","author":"Risher","year":"2014","journal-title":"eLife"},{"key":"10.1016\/j.biopsych.2025.02.904_bib24","doi-asserted-by":"crossref","first-page":"1219","DOI":"10.1007\/s00429-019-01831-x","article-title":"Cartography of hevin-expressing cells in the adult brain reveals prominent expression in astrocytes and parvalbumin neurons","volume":"224","author":"Mongr\u00e9dien","year":"2019","journal-title":"Brain Struct Funct"},{"key":"10.1016\/j.biopsych.2025.02.904_bib25","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.cell.2015.07.014","article-title":"Intact-brain analyses reveal distinct information carried by SNc dopamine subcircuits","volume":"162","author":"Lerner","year":"2015","journal-title":"Cell"},{"key":"10.1016\/j.biopsych.2025.02.904_bib26","doi-asserted-by":"crossref","first-page":"1936","DOI":"10.1038\/s41593-019-0492-2","article-title":"Accurate quantification of astrocyte and neurotransmitter fluorescence dynamics for single-cell and population-level physiology","volume":"22","author":"Wang","year":"2019","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.biopsych.2025.02.904_bib27","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.95873","article-title":"Astrocyte aquaporin mediates a tonic water efflux maintaining brain homeostasis","volume":"13","author":"Pham","year":"2024","journal-title":"eLife"},{"key":"10.1016\/j.biopsych.2025.02.904_bib28","doi-asserted-by":"crossref","first-page":"531","DOI":"10.1016\/j.neuron.2017.06.029","article-title":"Neural circuit-specialized astrocytes: Transcriptomic, proteomic, morphological, and functional evidence","volume":"95","author":"Chai","year":"2017","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2025.02.904_bib29","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1085\/jgp.201210949","article-title":"Imaging calcium microdomains within entire astrocyte territories and endfeet with GCaMPs expressed using adeno-associated viruses","volume":"141","author":"Shigetomi","year":"2013","journal-title":"J Gen Physiol"},{"key":"10.1016\/j.biopsych.2025.02.904_bib30","doi-asserted-by":"crossref","first-page":"683","DOI":"10.1016\/j.neuron.2016.01.040","article-title":"DREADDs for neuroscientists","volume":"89","author":"Roth","year":"2016","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2025.02.904_bib31","doi-asserted-by":"crossref","first-page":"1170","DOI":"10.1016\/j.neuron.2018.08.015","article-title":"Reducing astrocyte calcium signaling in vivo alters striatal microcircuits and causes repetitive behavior","volume":"99","author":"Yu","year":"2018","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2025.02.904_bib32","doi-asserted-by":"crossref","DOI":"10.1126\/science.adc9020","article-title":"Molecular basis of astrocyte diversity and morphology across the CNS in health and disease","volume":"378","author":"Endo","year":"2022","journal-title":"Science"},{"key":"10.1016\/j.biopsych.2025.02.904_bib33","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1126\/science.2994224","article-title":"Pathways of protein secretion in eukaryotes","volume":"230","author":"Kelly","year":"1985","journal-title":"Science"},{"key":"10.1016\/j.biopsych.2025.02.904_bib34","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1038\/s41596-019-0245-4","article-title":"Real-time imaging of multivesicular body-plasma membrane fusion to quantify exosome release from single cells","volume":"15","author":"Bebelman","year":"2020","journal-title":"Nat Protoc"},{"key":"10.1016\/j.biopsych.2025.02.904_bib35","doi-asserted-by":"crossref","first-page":"4212","DOI":"10.1073\/pnas.0607625104","article-title":"Two forms of single-vesicle astrocyte exocytosis imaged with total internal reflection fluorescence microscopy","volume":"104","author":"Bowser","year":"2007","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.biopsych.2025.02.904_bib36","doi-asserted-by":"crossref","first-page":"13815","DOI":"10.1523\/JNEUROSCI.5361-07.2008","article-title":"Trafficking and fusion of neuropeptide Y-containing dense-core granules in astrocytes","volume":"28","author":"Ramamoorthy","year":"2008","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2025.02.904_bib37","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1186\/s40478-021-01146-1","article-title":"Astrocytes respond to a neurotoxic A\u03b2 fragment with state-dependent Ca2+ alteration and multiphasic transmitter release","volume":"9","author":"Pham","year":"2021","journal-title":"Acta Neuropathol Commun"},{"key":"10.1016\/j.biopsych.2025.02.904_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2020.117069","article-title":"Mapping astrocyte activity domains by light sheet imaging and spatio-temporal correlation screening","volume":"220","author":"Pham","year":"2020","journal-title":"NeuroImage"},{"key":"10.1016\/j.biopsych.2025.02.904_bib39","doi-asserted-by":"crossref","first-page":"1779","DOI":"10.1038\/npp.2015.345","article-title":"Cell-type specific insertion of GluA2-lacking AMPARs with cocaine exposure leading to sensitization, cue-induced seeking, and incubation of craving","volume":"41","author":"Terrier","year":"2016","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.biopsych.2025.02.904_bib40","doi-asserted-by":"crossref","first-page":"7921","DOI":"10.1523\/JNEUROSCI.1859-07.2007","article-title":"Cocaine experience controls bidirectional synaptic plasticity in the nucleus accumbens","volume":"27","author":"Kourrich","year":"2007","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2025.02.904_bib41","doi-asserted-by":"crossref","first-page":"8613","DOI":"10.1523\/JNEUROSCI.17-21-08613.1997","article-title":"Decreased frequency but not amplitude of quantal synaptic responses associated with expression of corticostriatal long-term depression","volume":"17","author":"Choi","year":"1997","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2025.02.904_bib42","doi-asserted-by":"crossref","first-page":"5272","DOI":"10.1038\/s41467-022-33020-6","article-title":"Ca2+-modulated photoactivatable imaging reveals neuron-astrocyte glutamatergic circuitries within the nucleus accumbens","volume":"13","author":"Serra","year":"2022","journal-title":"Nat Commun"},{"key":"10.1016\/j.biopsych.2025.02.904_bib43","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1038\/nrn3725","article-title":"Astrocyte Ca2+ signalling: An unexpected complexity","volume":"15","author":"Volterra","year":"2014","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.biopsych.2025.02.904_bib44","doi-asserted-by":"crossref","first-page":"3453","DOI":"10.1523\/JNEUROSCI.3693-15.2016","article-title":"Dysfunctional calcium and glutamate signaling in striatal astrocytes from Huntington\u2019s disease model mice","volume":"36","author":"Jiang","year":"2016","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2025.02.904_bib45","doi-asserted-by":"crossref","DOI":"10.3389\/fncel.2024.1347491","article-title":"Astrocyte Ca2+ in the dorsal striatum suppresses neuronal activity to oppose cue-induced reinstatement of cocaine seeking","volume":"18","author":"Tavakoli","year":"2024","journal-title":"Front Cell Neurosci"},{"key":"10.1016\/j.biopsych.2025.02.904_bib46","doi-asserted-by":"crossref","first-page":"4154","DOI":"10.1523\/JNEUROSCI.4757-10.2011","article-title":"Astrocytes control glutamate receptor levels at developing synapses through SPARC-beta-integrin interactions","volume":"31","author":"Jones","year":"2011","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2025.02.904_bib47","doi-asserted-by":"crossref","DOI":"10.15252\/embj.2022111247","article-title":"Postnatal expression of CD38 in astrocytes regulates synapse formation and adult social memory","volume":"42","author":"Hattori","year":"2023","journal-title":"EMBO J"},{"key":"10.1016\/j.biopsych.2025.02.904_bib48","doi-asserted-by":"crossref","first-page":"4511","DOI":"10.1074\/jbc.271.8.4511","article-title":"Modulation of endothelial cell adhesion by hevin, an acidic protein associated with high endothelial venules","volume":"271","author":"Girard","year":"1996","journal-title":"J Biol Chem"},{"key":"10.1016\/j.biopsych.2025.02.904_bib49","doi-asserted-by":"crossref","first-page":"1123","DOI":"10.1054\/bjoc.1999.1051","article-title":"Hevin is down-regulated in many cancers and is a negative regulator of cell growth and proliferation","volume":"82","author":"Claeskens","year":"2000","journal-title":"Br J Cancer"},{"key":"10.1016\/j.biopsych.2025.02.904_bib50","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1111\/j.1524-475X.2008.00370.x","article-title":"Altered tissue repair in hevin-null mice: Inhibition of fibroblast migration by a matricellular SPARC homolog","volume":"16","author":"Sullivan","year":"2008","journal-title":"Wound Repair Regen"},{"key":"10.1016\/j.biopsych.2025.02.904_bib51","doi-asserted-by":"crossref","first-page":"2571","DOI":"10.1038\/s41418-021-00772-5","article-title":"Hevin-calcyon interaction promotes synaptic reorganization after brain injury","volume":"28","author":"Kim","year":"2021","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.biopsych.2025.02.904_bib52","doi-asserted-by":"crossref","first-page":"2895","DOI":"10.1002\/jnr.21735","article-title":"The extracellular matrix protein SC1\/hevin localizes to excitatory synapses following status epilepticus in the rat lithium-pilocarpine seizure model","volume":"86","author":"Lively","year":"2008","journal-title":"J Neurosci Res"},{"key":"10.1016\/j.biopsych.2025.02.904_bib53","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1016\/j.str.2021.01.003","article-title":"Interplay between hevin, SPARC, and MDGAs: Modulators of neurexin-neuroligin transsynaptic bridges","volume":"29","author":"Fan","year":"2021","journal-title":"Structure"},{"key":"10.1016\/j.biopsych.2025.02.904_bib54","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0030241","article-title":"Transfer of neuroplasticity from nucleus accumbens core to shell is required for cocaine reward","volume":"7","author":"Marie","year":"2012","journal-title":"PLOS One"},{"key":"10.1016\/j.biopsych.2025.02.904_bib55","doi-asserted-by":"crossref","first-page":"1986","DOI":"10.1038\/s41593-019-0524-y","article-title":"A ventral CA1 to nucleus accumbens core engram circuit mediates conditioned place preference for cocaine","volume":"22","author":"Zhou","year":"2019","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.biopsych.2025.02.904_bib56","doi-asserted-by":"crossref","first-page":"267","DOI":"10.1016\/j.tins.2010.02.002","article-title":"The addicted synapse: Mechanisms of synaptic and structural plasticity in nucleus accumbens","volume":"33","author":"Russo","year":"2010","journal-title":"Trends Neurosci"},{"key":"10.1016\/j.biopsych.2025.02.904_bib57","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1038\/s41380-021-01163-5","article-title":"Key transcription factors mediating cocaine-induced plasticity in the nucleus accumbens","volume":"27","author":"Teague","year":"2022","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.02.904_bib58","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1523\/JNEUROSCI.4466-06.2007","article-title":"Direct astrocytic contacts regulate local maturation of dendritic spines","volume":"27","author":"Nishida","year":"2007","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2025.02.904_bib59","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1126\/science.291.5504.657","article-title":"Control of synapse number by glia","volume":"291","author":"Ullian","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.biopsych.2025.02.904_bib60","doi-asserted-by":"crossref","first-page":"4230","DOI":"10.1038\/s41467-018-06519-0","article-title":"Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions","volume":"9","author":"Fornasiero","year":"2018","journal-title":"Nat Commun"},{"key":"10.1016\/j.biopsych.2025.02.904_bib61","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1038\/s41593-019-0537-6","article-title":"Silent synapses dictate cocaine memory destabilization and reconsolidation","volume":"23","author":"Wright","year":"2020","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.biopsych.2025.02.904_bib62","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1038\/nature06995","article-title":"Formation of accumbens GluR2-lacking AMPA receptors mediates incubation of cocaine craving","volume":"454","author":"Conrad","year":"2008","journal-title":"Nature"},{"key":"10.1016\/j.biopsych.2025.02.904_bib63","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/j.neuron.2009.06.007","article-title":"In vivo cocaine experience generates silent synapses","volume":"63","author":"Huang","year":"2009","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2025.02.904_bib64","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1093\/brain\/awt036","article-title":"Reduced D-serine levels in the nucleus accumbens of cocaine-treated rats hinder the induction of NMDA receptor-dependent synaptic plasticity","volume":"136","author":"Curcio","year":"2013","journal-title":"Brain"},{"key":"10.1016\/j.biopsych.2025.02.904_bib65","article-title":"Genetic liability underlying reward-related comorbidity in psychiatric disorders involves the coincident functions of autism-linked ADGRL1 and hevin","author":"Correoso-Bra\u00f1a","year":"2024","journal-title":"bioRxiv"},{"key":"10.1016\/j.biopsych.2025.02.904_bib66","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.1038\/nn.3846","article-title":"Synaptic plasticity mediating cocaine relapse requires matrix metalloproteinases","volume":"17","author":"Smith","year":"2014","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.biopsych.2025.02.904_bib67","doi-asserted-by":"crossref","first-page":"3093","DOI":"10.1002\/jcb.23235","article-title":"Proteolysis of the matricellular protein hevin by matrix metalloproteinase-3 produces a SPARC-like fragment (SLF) associated with neovasculature in a murine glioma model","volume":"112","author":"Weaver","year":"2011","journal-title":"J Cell Biochem"},{"key":"10.1016\/j.biopsych.2025.02.904_bib68","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.biopsych.2019.03.982","article-title":"Extracellular matrix signaling through \u03b23 integrin mediates cocaine cue-induced transient synaptic plasticity and relapse","volume":"86","author":"Garcia-Keller","year":"2019","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.02.904_bib69","doi-asserted-by":"crossref","first-page":"749","DOI":"10.1016\/j.neuron.2008.04.011","article-title":"Activity-dependent regulation of synaptic AMPA receptor composition and abundance by beta3 integrins","volume":"58","author":"Cingolani","year":"2008","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2025.02.904_bib70","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1097\/WNR.0000000000000053","article-title":"Sex differences in cocaine conditioned place preference in C57BL\/6J mice","volume":"25","author":"Hilderbrand","year":"2014","journal-title":"NeuroReport"},{"key":"10.1016\/j.biopsych.2025.02.904_bib71","article-title":"Sex-specific regulation of stress susceptibility by the astrocytic gene Htra1","author":"Parise","year":"2024","journal-title":"bioRxiv"},{"key":"10.1016\/j.biopsych.2025.02.904_bib72","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1038\/s41380-021-01112-2","article-title":"Cocaine-induced projection-specific and cell type-specific adaptations in the nucleus accumbens","volume":"27","author":"Zinsmaier","year":"2022","journal-title":"Mol Psychiatry"}],"container-title":["Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322325010728?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322325010728?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T08:22:22Z","timestamp":1777450942000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006322325010728"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":72,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,10]]}},"alternative-id":["S0006322325010728"],"URL":"https:\/\/doi.org\/10.1016\/j.biopsych.2025.02.904","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2023.03.19.533284","asserted-by":"object"}]},"ISSN":["0006-3223"],"issn-type":[{"value":"0006-3223","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Astrocytes Control Cocaine-Induced Synaptic Plasticity and Reward Through the Matricellular Protein Hevin","name":"articletitle","label":"Article Title"},{"value":"Biological Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopsych.2025.02.904","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Society of Biological Psychiatry.","name":"copyright","label":"Copyright"}]}}