{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,4]],"date-time":"2026-07-04T07:50:00Z","timestamp":1783151400773,"version":"3.54.6"},"reference-count":71,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T00:00:00Z","timestamp":1762128000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100007185","name":"University of California, Los Angeles","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007185","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001945","name":"American Psychological Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001945","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000025","name":"NIMH","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000025","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["U01MH109977"],"award-info":[{"award-number":["U01MH109977"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["biologicalpsychiatryjournal.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biological Psychiatry"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.biopsych.2025.10.024","type":"journal-article","created":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T01:33:31Z","timestamp":1761788011000},"page":"178-188","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Multivariate Resting-State Functional Connectivity Features Linked to Transdiagnostic Psychopathology in Early Psychosis"],"prefix":"10.1016","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8042-8343","authenticated-orcid":false,"given":"Haley R.","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen-Qi","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason S.","family":"Nomi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Charles H.","family":"Schleifer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carrie E.","family":"Bearden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bratislav","family":"Misic","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucina Q.","family":"Uddin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3332-4231","authenticated-orcid":false,"given":"Katherine H.","family":"Karlsgodt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biopsych.2025.10.024_bib1","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1016\/j.biopsych.2024.06.011","article-title":"Decoding early psychoses: Unraveling stable microstructural features associated with psychopathology across independent cohorts","volume":"97","author":"Wang","year":"2025","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.024_bib2","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1146\/annurev-clinpsy-032814-112915","article-title":"Etiologic, phenomenologic, and endophenotypic overlap of schizophrenia and bipolar disorder","volume":"11","author":"Pearlson","year":"2015","journal-title":"Annu Rev Clin Psychol"},{"key":"10.1016\/j.biopsych.2025.10.024_bib3","doi-asserted-by":"crossref","DOI":"10.3389\/fnins.2021.682110","article-title":"Whole-brain functional network connectivity abnormalities in affective and non-affective early phase psychosis","volume":"15","author":"Fu","year":"2021","journal-title":"Front Neurosci"},{"key":"10.1016\/j.biopsych.2025.10.024_bib4","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1093\/schbul\/sbx034","article-title":"Dysfunction of large-scale brain networks in schizophrenia: A meta-analysis of resting-state functional connectivity","volume":"44","author":"Dong","year":"2018","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.biopsych.2025.10.024_bib5","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.conb.2014.10.005","article-title":"How can studies of resting-state functional connectivity help us understand psychosis as a disorder of brain development?","volume":"30","author":"Satterthwaite","year":"2015","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.biopsych.2025.10.024_bib6","doi-asserted-by":"crossref","first-page":"1092","DOI":"10.1176\/appi.ajp.2012.12010056","article-title":"Thalamocortical dysconnectivity in schizophrenia","volume":"169","author":"Woodward","year":"2012","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.024_bib7","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.neures.2014.08.006","article-title":"The course of neuropsychological impairment and brain structure abnormalities in psychotic disorders","volume":"102","author":"Woodward","year":"2016","journal-title":"Neurosci Res"},{"key":"10.1016\/j.biopsych.2025.10.024_bib8","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1093\/schbul\/sbt092","article-title":"Resting-state fMRI connectivity impairment in schizophrenia and bipolar disorder","volume":"40","author":"Argyelan","year":"2014","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.biopsych.2025.10.024_bib9","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.biopsych.2018.12.003","article-title":"Specific substantial dysconnectivity in schizophrenia: A transdiagnostic multimodal meta-analysis of resting-state functional and structural magnetic resonance imaging studies","volume":"85","author":"Brandl","year":"2019","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.024_bib10","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1001\/jamapsychiatry.2013.3469","article-title":"Disruption of cortical association networks in schizophrenia and psychotic bipolar disorder","volume":"71","author":"Baker","year":"2014","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.024_bib11","doi-asserted-by":"crossref","first-page":"1279","DOI":"10.1073\/pnas.0809141106","article-title":"Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia","volume":"106","author":"Whitfield-Gabrieli","year":"2009","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biopsych.2025.10.024_bib12","doi-asserted-by":"crossref","first-page":"386","DOI":"10.1001\/jamapsychiatry.2017.4741","article-title":"Multivariate associations among behavioral, clinical, and multimodal imaging phenotypes in patients with psychosis","volume":"75","author":"Moser","year":"2018","journal-title":"JAMA Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.024_bib13","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.neuroimage.2017.10.022","article-title":"Dynamic functional connectivity impairments in early schizophrenia and clinical high-risk for psychosis","volume":"180","author":"Du","year":"2018","journal-title":"NeuroImage"},{"key":"10.1016\/j.biopsych.2025.10.024_bib14","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1016\/j.jad.2013.05.083","article-title":"A systematic literature review of resting state network\u2014Functional MRI in bipolar disorder","volume":"150","author":"Vargas","year":"2013","journal-title":"J Affect Disord"},{"key":"10.1016\/j.biopsych.2025.10.024_bib15","doi-asserted-by":"crossref","first-page":"529","DOI":"10.1148\/radiol.2016151641","article-title":"Disrupted resting-state functional connectivity in nonmedicated bipolar disorder","volume":"280","author":"Wang","year":"2016","journal-title":"Radiology"},{"key":"10.1016\/j.biopsych.2025.10.024_bib16","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1016\/j.biopsych.2012.01.025","article-title":"Differences in resting-state functional magnetic resonance imaging functional network connectivity between schizophrenia and psychotic bipolar probands and their unaffected first-degree relatives","volume":"71","author":"Meda","year":"2012","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.024_bib17","first-page":"488","article-title":"Examining functional resting-state connectivity in psychosis and its subgroups in the bipolar-schizophrenia network on intermediate phenotypes cohort","volume":"1","author":"Meda","year":"2016","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging"},{"key":"10.1016\/j.biopsych.2025.10.024_bib18","doi-asserted-by":"crossref","first-page":"367","DOI":"10.1016\/j.jad.2016.09.041","article-title":"Differential brain network activity across mood states in bipolar disorder","volume":"207","author":"Brady","year":"2017","journal-title":"J Affect Disord"},{"key":"10.1016\/j.biopsych.2025.10.024_bib19","first-page":"153","article-title":"Resting-state functional nuclear magnetic resonance imaging in patients with bipolar disorder: Beyond euthymia","volume":"51","author":"Soto-Vega","year":"2022","journal-title":"Rev Colomb Psiquiatr (Engl Ed)"},{"key":"10.1016\/j.biopsych.2025.10.024_bib20","doi-asserted-by":"crossref","first-page":"9050","DOI":"10.1073\/pnas.1820780116","article-title":"Functional connectomics of affective and psychotic pathology","volume":"116","author":"Baker","year":"2019","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biopsych.2025.10.024_bib21","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.biopsych.2019.06.013","article-title":"Somatosensory-motor dysconnectivity spans multiple transdiagnostic dimensions of psychopathology","volume":"86","author":"Kebets","year":"2019","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.024_bib22","first-page":"961","article-title":"Non-negative matrix factorization reveals resting-state cortical alpha network abnormalities in the first-episode schizophrenia spectrum","volume":"5","author":"Phalen","year":"2020","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging"},{"key":"10.1016\/j.biopsych.2025.10.024_bib23","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.1038\/s41380-021-01319-3","article-title":"Dynamic and progressive changes in thalamic functional connectivity over the first five years of psychosis","volume":"27","author":"Chan","year":"2022","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.024_bib24","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.1111\/j.1469-7610.2011.02443.x","article-title":"Two-year diagnostic stability in early-onset first-episode psychosis","volume":"52","author":"Castro-Fornieles","year":"2011","journal-title":"J Child Psychol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.024_bib25","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.biopsych.2020.06.028","article-title":"Adolescent neurodevelopment and vulnerability to psychosis","volume":"89","author":"Patel","year":"2021","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.024_bib26","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1016\/j.conb.2020.10.016","article-title":"Towards precise resting-state fMRI biomarkers in psychiatry: Synthesizing developments in transdiagnostic research, dimensional models of psychopathology, and normative neurodevelopment","volume":"65","author":"Parkes","year":"2020","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.biopsych.2025.10.024_bib27","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.schres.2022.12.041","article-title":"Altered intrinsic cerebellar-cerebral functional connectivity is related to negative symptoms in patients with first-episode psychosis","volume":"252","author":"Choi","year":"2023","journal-title":"Schizophr Res"},{"key":"10.1016\/j.biopsych.2025.10.024_bib28","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1162\/netn_a_00363","article-title":"Comparing the stability and reproducibility of brain-behavior relationships found using canonical correlation analysis and partial least squares within the ABCD sample","volume":"8","author":"Nakua","year":"2024","journal-title":"Netw Neurosci"},{"key":"10.1016\/j.biopsych.2025.10.024_bib29","doi-asserted-by":"crossref","first-page":"499","DOI":"10.1146\/annurev-psych-113011-143804","article-title":"Multivariate statistical analyses for neuroimaging data","volume":"64","author":"McIntosh","year":"2013","journal-title":"Annu Rev Psychol"},{"key":"10.1016\/j.biopsych.2025.10.024_bib30","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1038\/s41398-024-02954-4","article-title":"Multivariate brain-behaviour associations in psychiatric disorders","volume":"14","author":"Vieira","year":"2024","journal-title":"Transl Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.024_bib32","doi-asserted-by":"crossref","DOI":"10.3389\/fninf.2023.1104508","article-title":"QuNex-An integrative platform for reproducible neuroimaging analytics","volume":"17","author":"Ji","year":"2023","journal-title":"Front Neuroinform"},{"key":"10.1016\/j.biopsych.2025.10.024_bib33","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1038\/nature18933","article-title":"A multi-modal parcellation of human cerebral cortex","volume":"536","author":"Glasser","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.biopsych.2025.10.024_bib34","doi-asserted-by":"crossref","first-page":"7438","DOI":"10.1073\/pnas.1405289111","article-title":"Altered global brain signal in schizophrenia","volume":"111","author":"Yang","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biopsych.2025.10.024_bib35","doi-asserted-by":"crossref","first-page":"482","DOI":"10.3389\/fpsyt.2019.00482","article-title":"Dysconnectivity of multiple brain networks in schizophrenia: A meta-analysis of resting-state functional connectivity","volume":"10","author":"Li","year":"2019","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.024_bib36","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/j.schres.2020.03.035","article-title":"Global fMRI signal at rest relates to symptom severity in schizophrenia","volume":"220","author":"Umeh","year":"2020","journal-title":"Schizophr Res"},{"key":"10.1016\/j.biopsych.2025.10.024_bib37","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.neuroimage.2016.11.052","article-title":"Towards a consensus regarding global signal regression for resting state functional connectivity MRI","volume":"154","author":"Murphy","year":"2017","journal-title":"NeuroImage"},{"key":"10.1016\/j.biopsych.2025.10.024_bib38","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1038\/s41386-024-01888-1","article-title":"Resting state functional brain connectivity in child and adolescent psychiatry: Where are we now?","volume":"50","author":"Uddin","year":"2025","journal-title":"Neuropsychopharmacol"},{"key":"10.1016\/j.biopsych.2025.10.024_bib39","doi-asserted-by":"crossref","first-page":"3095","DOI":"10.1093\/cercor\/bhx179","article-title":"Local-global parcellation of the human cerebral cortex from intrinsic functional connectivity MRI","volume":"28","author":"Schaefer","year":"2018","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.biopsych.2025.10.024_bib40","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1038\/s41593-020-00711-6","article-title":"Topographic organization of the human subcortex unveiled with functional connectivity gradients","volume":"23","author":"Tian","year":"2020","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.biopsych.2025.10.024_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuroimage.2019.116450","article-title":"Harmonization of large MRI datasets for the analysis of brain imaging patterns throughout the lifespan","volume":"208","author":"Pomponio","year":"2020","journal-title":"NeuroImage"},{"key":"10.1016\/j.biopsych.2025.10.024_bib42","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1093\/schbul\/13.2.261","article-title":"The Positive and Negative Syndrome Scale (PANSS) for schizophrenia","volume":"13","author":"Kay","year":"1987","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.biopsych.2025.10.024_bib43","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1192\/bjp.133.5.429","article-title":"A rating scale for mania: Reliability, validity and sensitivity","volume":"133","author":"Young","year":"1978","journal-title":"Br J Psychiatry"},{"issue":"suppl 3","key":"10.1016\/j.biopsych.2025.10.024_bib44","first-page":"S76","article-title":"Emotion assessment using the NIH Toolbox","volume":"80","author":"Salsman","year":"2013","journal-title":"Neurology"},{"key":"10.1016\/j.biopsych.2025.10.024_bib45","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/j.psychres.2012.09.034","article-title":"Assessment of self-reported negative affect in the NIH Toolbox","volume":"206","author":"Pilkonis","year":"2013","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.biopsych.2025.10.024_bib46","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1111\/j.1559-1816.2012.00900.x","article-title":"Who\u2019s stressed? Distributions of psychological stress in the United States in probability samples from 1983, 2006, and 2009","volume":"42","author":"Cohen","year":"2012","journal-title":"J Appl Soc Psychol"},{"key":"10.1016\/j.biopsych.2025.10.024_bib47","doi-asserted-by":"crossref","first-page":"991","DOI":"10.1093\/jpepsy\/jsac037","article-title":"Assessing aspects of social relationships in youth across middle childhood and adolescence: The NIH Toolbox Pediatric Social Relationship Scales","volume":"47","author":"Dietz","year":"2022","journal-title":"J Pediatr Psychol"},{"key":"10.1016\/j.biopsych.2025.10.024_bib48","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1007\/s11136-013-0452-3","article-title":"Assessing psychological well-being: Self-report instruments for the NIH Toolbox","volume":"23","author":"Salsman","year":"2014","journal-title":"Qual Life Res"},{"key":"10.1016\/j.biopsych.2025.10.024_bib49","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1038\/s41583-021-00428-w","article-title":"Cognitive and behavioural flexibility: Neural mechanisms and clinical considerations","volume":"22","author":"Uddin","year":"2021","journal-title":"Nat Rev Neurosci"},{"key":"10.1016\/j.biopsych.2025.10.024_bib50","article-title":"Cognitive flexibility in neurodevelopmental disorders: Insights from neuroimaging and neuropsychology","volume":"59","author":"Koithan","year":"2024","journal-title":"Curr Opin Behav Sci"},{"key":"10.1016\/j.biopsych.2025.10.024_bib51","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1093\/scan\/nsy107","article-title":"Tracking mood fluctuations with functional network patterns","volume":"14","author":"Mirchi","year":"2019","journal-title":"Soc Cogn Affect Neurosci"},{"key":"10.1016\/j.biopsych.2025.10.024_bib52","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1093\/schbul\/sbq168","article-title":"Emotion effects on attention, amygdala activation, and functional connectivity in schizophrenia","volume":"38","author":"Anticevic","year":"2012","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.biopsych.2025.10.024_bib53","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1111\/j.1399-5618.2012.01021.x","article-title":"Emotion processing and regulation in bipolar disorder: A review","volume":"14","author":"Townsend","year":"2012","journal-title":"Bipolar Disord"},{"key":"10.1016\/j.biopsych.2025.10.024_bib54","doi-asserted-by":"crossref","DOI":"10.1016\/j.psychres.2020.113427","article-title":"Pathways to aggression and violence in psychosis without longstanding antisocial behavior: A review and proposed psychosocial model for integrative clinical interventions","volume":"293","author":"Adams","year":"2020","journal-title":"Psychiatry Res"},{"key":"10.1016\/j.biopsych.2025.10.024_bib55","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/7854_2024_539","article-title":"Disentangling the neural circuits of arousal and anxiety-like behavior","volume":"73","author":"Florido","year":"2025","journal-title":"Curr Top Behav Neurosci"},{"key":"10.1016\/j.biopsych.2025.10.024_bib56","doi-asserted-by":"crossref","first-page":"1110","DOI":"10.1093\/schbul\/sbw078","article-title":"Auditory hallucinations and the brain\u2019s resting-state networks: Findings and methodological observations","volume":"42","author":"Alderson-Day","year":"2016","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.biopsych.2025.10.024_bib57","doi-asserted-by":"crossref","first-page":"456","DOI":"10.3389\/fnhum.2018.00456","article-title":"Altered effective connectivity in the default network of the brains of first-episode, drug-na\u00efve schizophrenia patients with auditory verbal hallucinations","volume":"12","author":"Zhao","year":"2018","journal-title":"Front Hum Neurosci"},{"key":"10.1016\/j.biopsych.2025.10.024_bib58","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1093\/schbul\/sbx067","article-title":"Abnormal resting-state connectivity in a substantia nigra-related striato-thalamo-cortical network in a large sample of first-episode drug-naive patients with schizophrenia","volume":"44","author":"Martino","year":"2018","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.biopsych.2025.10.024_bib59","first-page":"443","article-title":"Dynamic functional connectivity states reflecting psychotic-like experiences","volume":"3","author":"Barber","year":"2018","journal-title":"Biol Psychiatry Cogn Neurosci Neuroimaging"},{"key":"10.1016\/j.biopsych.2025.10.024_bib60","doi-asserted-by":"crossref","first-page":"E2066","DOI":"10.1073\/pnas.1313093111","article-title":"Multivariate analysis reveals genetic associations of the resting default mode network in psychotic bipolar disorder and schizophrenia","volume":"111","author":"Meda","year":"2014","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biopsych.2025.10.024_bib61","doi-asserted-by":"crossref","first-page":"3116","DOI":"10.1093\/cercor\/bht165","article-title":"Characterizing thalamo-cortical disturbances in schizophrenia and bipolar illness","volume":"24","author":"Anticevic","year":"2014","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.biopsych.2025.10.024_bib62","doi-asserted-by":"crossref","first-page":"811","DOI":"10.1001\/archgenpsychiatry.2009.91","article-title":"Meta-analysis of 41 functional neuroimaging studies of executive function in schizophrenia","volume":"66","author":"Minzenberg","year":"2009","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.024_bib63","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.schres.2016.08.005","article-title":"Review of thalamocortical resting-state fMRI studies in schizophrenia","volume":"180","author":"Giraldo-Chica","year":"2017","journal-title":"Schizophr Res"},{"key":"10.1016\/j.biopsych.2025.10.024_bib64","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.schres.2017.11.013","article-title":"Abnormal brain activation during threatening face processing in schizophrenia: A meta-analysis of functional neuroimaging studies","volume":"197","author":"Dong","year":"2018","journal-title":"Schizophr Res"},{"key":"10.1016\/j.biopsych.2025.10.024_bib65","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1176\/appi.ajp.2011.10081191","article-title":"At clinical high risk for psychosis: Outcome for nonconverters","volume":"168","author":"Addington","year":"2011","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.024_bib66","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1007\/s00127-016-1182-y","article-title":"Early traumatic experiences, perceived discrimination and conversion to psychosis in those at clinical high risk for psychosis","volume":"51","author":"Stowkowy","year":"2016","journal-title":"Soc Psychiatry Psychiatr Epidemiol"},{"key":"10.1016\/j.biopsych.2025.10.024_bib67","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.schres.2018.05.003","article-title":"Childhood trauma and clinical high risk for psychosis","volume":"205","author":"Loewy","year":"2019","journal-title":"Schizophr Res"},{"key":"10.1016\/j.biopsych.2025.10.024_bib68","doi-asserted-by":"crossref","first-page":"661","DOI":"10.1093\/schbul\/sbs050","article-title":"Childhood adversities increase the risk of psychosis: A meta-analysis of patient-control, prospective- and cross-sectional cohort studies","volume":"38","author":"Varese","year":"2012","journal-title":"Schizophr Bull"},{"key":"10.1016\/j.biopsych.2025.10.024_bib69","doi-asserted-by":"crossref","first-page":"4740","DOI":"10.1093\/cercor\/bhu161","article-title":"Brain state differentiation and behavioral inflexibility in autism","volume":"25","author":"Uddin","year":"2015","journal-title":"Cereb Cortex"},{"key":"10.1016\/j.biopsych.2025.10.024_bib70","doi-asserted-by":"crossref","first-page":"2557","DOI":"10.1017\/S0033291719002708","article-title":"Comprehensive comparison of social cognitive performance in autism spectrum disorder and schizophrenia","volume":"50","author":"Pinkham","year":"2020","journal-title":"Psychol Med"},{"key":"10.1016\/j.biopsych.2025.10.024_bib71","doi-asserted-by":"crossref","first-page":"614","DOI":"10.3389\/fpsyt.2020.00614","article-title":"A review of default mode network connectivity and its association with social cognition in adolescents with autism spectrum disorder and early-onset psychosis","volume":"11","author":"Nair","year":"2020","journal-title":"Front Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.024_bib72","doi-asserted-by":"crossref","first-page":"33","DOI":"10.3389\/fpsyt.2017.00033","article-title":"Early psychosis and trauma-related disorders: Clinical practice guidelines and future directions","volume":"8","author":"Cragin","year":"2017","journal-title":"Front Psychiatry"}],"container-title":["Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322325015732?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322325015732?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T12:26:41Z","timestamp":1782476801000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006322325015732"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":71,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S0006322325015732"],"URL":"https:\/\/doi.org\/10.1016\/j.biopsych.2025.10.024","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2025.06.04.654984","asserted-by":"object"}]},"ISSN":["0006-3223"],"issn-type":[{"value":"0006-3223","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Multivariate Resting-State Functional Connectivity Features Linked to Transdiagnostic Psychopathology in Early Psychosis","name":"articletitle","label":"Article Title"},{"value":"Biological Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopsych.2025.10.024","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Society of Biological Psychiatry.","name":"copyright","label":"Copyright"}]}}