{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T13:51:47Z","timestamp":1792504307729,"version":"4.5.0"},"reference-count":42,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,21]],"date-time":"2026-01-21T00:00:00Z","timestamp":1768953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000738","name":"U.S. Department of Veterans Affairs","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000738","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001455","name":"American Foundation for Suicide Prevention","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100001455","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007217","name":"Health Services Research and Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100007217","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004823","name":"Connecticut State Department of Mental Health and Addiction Services","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004823","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000874","name":"Brain and Behavior Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000874","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["R01 AA031017"],"award-info":[{"award-number":["R01 AA031017"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"NIH","doi-asserted-by":"publisher","award":["DP1 DA060811"],"award-info":[{"award-number":["DP1 DA060811"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["biologicalpsychiatryjournal.com","clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biological Psychiatry"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.biopsych.2025.10.032","type":"journal-article","created":{"date-parts":[[2025,11,3]],"date-time":"2025-11-03T15:59:16Z","timestamp":1762185556000},"page":"76-87","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Mapping DNA Methylation Signatures to Identify Epigenetic Variation Across Subcortical Regions of the Human Posttraumatic Stress Disorder Brain"],"prefix":"10.1016","volume":"100","author":[{"given":"Hongyu","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yujing","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yiming","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiawei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tuan P.","family":"Nguyen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuhan","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wangjie","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youshu","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dianne A.","family":"Cruz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer L.","family":"Modliszewski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosemarie","family":"Terwilliger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexa-Nicole","family":"Sliby","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9 Jaime","family":"Mart\u00ednez-Maga\u00f1a","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janitza L.","family":"Montalvo-Ortiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John D.","family":"Roache","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lynnette A.","family":"Averill","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stacey","family":"Young-McCaughan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paulo R.","family":"Shiroma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand R.","family":"Huber","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David A.","family":"Lewis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jill","family":"Glausier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paul","family":"Holtzheimer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew J.","family":"Friedman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan L.","family":"Peterson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chadi G.","family":"Abdallah","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Valizadeh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John H.","family":"Krystal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald S.","family":"Duman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongyu","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David L.","family":"Corcoran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas E.","family":"Williamson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1647-326X","authenticated-orcid":false,"given":"Matthew J.","family":"Girgenti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"suppl 17","key":"10.1016\/j.biopsych.2025.10.032_bib1","first-page":"16","article-title":"The epidemiology of posttraumatic stress disorder: What is the extent of the problem?","volume":"62","author":"Breslau","year":"2001","journal-title":"J Clin Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.032_bib2","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.biopsych.2014.03.028","article-title":"Subthreshold posttraumatic stress disorder in the World Health Organization world mental health surveys","volume":"77","author":"McLaughlin","year":"2015","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.032_bib3","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1093\/oxfordjournals.aje.a009457","article-title":"Risk factors for DSM-III-R posttraumatic stress disorder: Findings from the National Comorbidity Survey","volume":"147","author":"Bromet","year":"1998","journal-title":"Am J Epidemiol"},{"key":"10.1016\/j.biopsych.2025.10.032_bib4","doi-asserted-by":"crossref","first-page":"141","DOI":"10.31887\/DCNS.2015.17.2\/jflory","article-title":"Comorbidity between post-traumatic stress disorder and major depressive disorder: Alternative explanations and treatment considerations","volume":"17","author":"Flory","year":"2015","journal-title":"Dial Clin Neurosci"},{"key":"10.1016\/j.biopsych.2025.10.032_bib5","doi-asserted-by":"crossref","first-page":"456","DOI":"10.1016\/j.janxdis.2010.11.010","article-title":"Prevalence and Axis I comorbidity of full and partial posttraumatic stress disorder in the United States: Results from Wave 2 of the National Epidemiologic Survey on alcohol and Related Conditions","volume":"25","author":"Pietrzak","year":"2011","journal-title":"J Anxiety Disord"},{"key":"10.1016\/j.biopsych.2025.10.032_bib6","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1038\/npp.2012.112","article-title":"DNA methylation and its basic function","volume":"38","author":"Moore","year":"2013","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.biopsych.2025.10.032_bib7","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1038\/nature10524","article-title":"Temporal dynamics and genetic control of transcription in the human prefrontal cortex","volume":"478","author":"Colantuoni","year":"2011","journal-title":"Nature"},{"key":"10.1016\/j.biopsych.2025.10.032_bib8","doi-asserted-by":"crossref","first-page":"260","DOI":"10.1016\/j.ajhg.2011.12.020","article-title":"DNA methylation signatures in development and aging of the human prefrontal cortex [published correction appears in Am J Hum Genet 2012; 91:765]","volume":"90","author":"Numata","year":"2012","journal-title":"Am J Hum Genet"},{"key":"10.1016\/j.biopsych.2025.10.032_bib9","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1038\/npp.2012.125","article-title":"The dynamics of DNA methylation in schizophrenia and related psychiatric disorders","volume":"38","author":"Grayson","year":"2013","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.biopsych.2025.10.032_bib10","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1038\/nn.4181","article-title":"Mapping DNA methylation across development, genotype and schizophrenia in the human frontal cortex","volume":"19","author":"Jaffe","year":"2016","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.biopsych.2025.10.032_bib11","doi-asserted-by":"crossref","first-page":"5251","DOI":"10.1038\/s41467-021-25517-3","article-title":"Genome-wide sequencing-based identification of methylation quantitative trait loci and their role in schizophrenia risk","volume":"12","author":"Perzel Mandell","year":"2021","journal-title":"Nat Commun"},{"key":"10.1016\/j.biopsych.2025.10.032_bib12","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms10967","article-title":"Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans","volume":"7","author":"Houtepen","year":"2016","journal-title":"Nat Commun"},{"key":"10.1016\/j.biopsych.2025.10.032_bib13","article-title":"Preclinical and clinical evidence of DNA methylation changes in response to trauma and chronic stress","volume":"1","author":"Matosin","year":"2017","journal-title":"Chronic Stress (Thousand Oaks)"},{"key":"10.1016\/j.biopsych.2025.10.032_bib14","doi-asserted-by":"crossref","first-page":"700","DOI":"10.1002\/ajmg.b.31212","article-title":"Differential immune system DNA methylation and cytokine regulation in post-traumatic stress disorder","volume":"156B","author":"Smith","year":"2011","journal-title":"Am J Med Genet B Neuropsychiatr Genet"},{"key":"10.1016\/j.biopsych.2025.10.032_bib15","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1111\/acps.12778","article-title":"Genomewide DNA methylation analysis in combat veterans reveals a novel locus for PTSD","volume":"136","author":"Mehta","year":"2017","journal-title":"Acta Psychiatr Scand"},{"key":"10.1016\/j.biopsych.2025.10.032_bib16","doi-asserted-by":"crossref","first-page":"1145","DOI":"10.1038\/mp.2017.120","article-title":"Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder","volume":"23","author":"Rutten","year":"2018","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.032_bib17","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s13148-020-0820-0","article-title":"An epigenome-wide association study of posttraumatic stress disorder in US veterans implicates several new DNA methylation loci","volume":"12","author":"Logue","year":"2020","journal-title":"Clin Epigenet"},{"key":"10.1016\/j.biopsych.2025.10.032_bib18","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1001\/archpsyc.1993.01820160064008","article-title":"Psychobiologic mechanisms of posttraumatic stress disorder","volume":"50","author":"Charney","year":"1993","journal-title":"Arch Gen Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.032_bib19","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1016\/0959-4388(92)90011-9","article-title":"Brain mechanisms of emotion and emotional learning","volume":"2","author":"LeDoux","year":"1992","journal-title":"Curr Opin Neurobiol"},{"key":"10.1016\/j.biopsych.2025.10.032_bib20","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/0166-4328(93)90102-V","article-title":"Fear-potentiated startle: A neural and pharmacological analysis","volume":"58","author":"Davis","year":"1993","journal-title":"Behav Brain Res"},{"key":"10.1016\/j.biopsych.2025.10.032_bib21","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1523\/JNEUROSCI.02-06-00791.1982","article-title":"A primary acoustic startle circuit: Lesion and stimulation studies","volume":"2","author":"Davis","year":"1982","journal-title":"J Neurosci"},{"key":"10.1016\/j.biopsych.2025.10.032_bib22","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1016\/S0896-6273(00)80475-4","article-title":"Human amygdala activation during conditioned fear acquisition and extinction: A mixed-trial fMRI study","volume":"20","author":"LaBar","year":"1998","journal-title":"Neuron"},{"key":"10.1016\/j.biopsych.2025.10.032_bib23","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1017\/S0033291704003290","article-title":"Positron emission tomographic imaging of neural correlates of a fear acquisition and extinction paradigm in women with childhood sexual-abuse-related post-traumatic stress disorder","volume":"35","author":"Bremner","year":"2005","journal-title":"Psychol Med"},{"key":"10.1016\/j.biopsych.2025.10.032_bib24","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1176\/appi.ajp.161.1.36","article-title":"The nature of traumatic memories: A 4-T fMRI functional connectivity analysis","volume":"161","author":"Lanius","year":"2004","journal-title":"Am J Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.032_bib25","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1016\/j.biopsych.2017.09.006","article-title":"Smaller hippocampal volume in posttraumatic stress disorder: A multisite ENIGMA-PGC study: Subcortical volumetry results from posttraumatic stress disorder consortia","volume":"83","author":"Logue","year":"2018","journal-title":"Biol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.032_bib26","doi-asserted-by":"crossref","DOI":"10.1126\/science.adh3707","article-title":"Systems biology dissection of PTSD and MDD across brain regions, cell types, and blood","volume":"384","author":"Daskalakis","year":"2024","journal-title":"Science"},{"key":"10.1016\/j.biopsych.2025.10.032_bib27","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1002\/jts.21814","article-title":"The co-occurrence of major depressive disorder among individuals with posttraumatic stress disorder: A meta-analysis","volume":"26","author":"Rytwinski","year":"2013","journal-title":"J Trauma Stress"},{"key":"10.1016\/j.biopsych.2025.10.032_bib28","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1038\/s41593-020-00748-7","article-title":"Transcriptomic organization of the human brain in post-traumatic stress disorder","volume":"24","author":"Girgenti","year":"2021","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.biopsych.2025.10.032_bib29","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1038\/s41586-025-09083-y","article-title":"Single-cell transcriptomic and chromatin dynamics of the human brain in PTSD","volume":"643","author":"Hwang","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.biopsych.2025.10.032_bib30","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1038\/s41588-020-00767-x","article-title":"Genome-wide association analyses of post-traumatic stress disorder and its symptom subdomains in the Million Veteran Program","volume":"53","author":"Stein","year":"2021","journal-title":"Nat Genet"},{"key":"10.1016\/j.biopsych.2025.10.032_bib31","doi-asserted-by":"crossref","first-page":"1446","DOI":"10.1093\/bioinformatics\/btw026","article-title":"Differential methylation analysis for BS-seq data under general experimental design","volume":"32","author":"Park","year":"2016","journal-title":"Bioinformatics"},{"key":"10.1016\/j.biopsych.2025.10.032_bib32","doi-asserted-by":"crossref","DOI":"10.1093\/nar\/gku154","article-title":"A Bayesian hierarchical model to detect differentially methylated loci from single nucleotide resolution sequencing data","volume":"42","author":"Feng","year":"2014","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.biopsych.2025.10.032_bib33","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1038\/s41592-018-0213-x","article-title":"Identification of differentially methylated cell types in epigenome-wide association studies","volume":"15","author":"Zheng","year":"2018","journal-title":"Nat Methods"},{"key":"10.1016\/j.biopsych.2025.10.032_bib34","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1038\/s41386-022-01266-9","article-title":"Dose-related effects of ketamine for antidepressant-resistant symptoms of posttraumatic stress disorder in veterans and active duty military: A double-blind, randomized, placebo-controlled multi-center clinical trial","volume":"47","author":"Abdallah","year":"2022","journal-title":"Neuropsychopharmacology"},{"key":"10.1016\/j.biopsych.2025.10.032_bib35","doi-asserted-by":"crossref","first-page":"2360","DOI":"10.1038\/s41467-020-15930-5","article-title":"PTSD is associated with neuroimmune suppression: Evidence from PET imaging and postmortem transcriptomic studies","volume":"11","author":"Bhatt","year":"2020","journal-title":"Nat Commun"},{"key":"10.1016\/j.biopsych.2025.10.032_bib36","doi-asserted-by":"crossref","first-page":"601","DOI":"10.1016\/j.tig.2025.01.001","article-title":"Chromatin accessibility provides a window into the genetic etiology of human brain disease","volume":"41","author":"Bendl","year":"2025","journal-title":"Trends Genet"},{"key":"10.1016\/j.biopsych.2025.10.032_bib37","doi-asserted-by":"crossref","first-page":"523","DOI":"10.1093\/bioinformatics\/btt703","article-title":"Causal analysis approaches in Ingenuity Pathway Analysis","volume":"30","author":"Kr\u00e4mer","year":"2014","journal-title":"Bioinformatics"},{"key":"10.1016\/j.biopsych.2025.10.032_bib38","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1038\/mp.2016.250","article-title":"Estrogen-dependent association of HDAC4 with fear in female mice and women with PTSD","volume":"23","author":"Maddox","year":"2018","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.032_bib39","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1038\/s41593-021-00860-2","article-title":"Bi-ancestral depression GWAS in the Million Veteran Program and meta-analysis in >1.2 million individuals highlight new therapeutic directions","volume":"24","author":"Levey","year":"2021","journal-title":"Nat Neurosci"},{"key":"10.1016\/j.biopsych.2025.10.032_bib40","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1038\/mp.2013.138","article-title":"Polygenic dissection of diagnosis and clinical dimensions of bipolar disorder and schizophrenia","volume":"19","author":"Ruderfer","year":"2014","journal-title":"Mol Psychiatry"},{"key":"10.1016\/j.biopsych.2025.10.032_bib41","doi-asserted-by":"crossref","first-page":"826","DOI":"10.3390\/ijms21030826","article-title":"The relationship between DNA methylation and antidepressant medications: A systematic review","volume":"21","author":"Webb","year":"2020","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.biopsych.2025.10.032_bib42","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/s13148-019-0798-7","article-title":"Longitudinal epigenome-wide association studies of three male military cohorts reveal multiple CpG sites associated with post-traumatic stress disorder","volume":"12","author":"Snijders","year":"2020","journal-title":"Clin Epigenet"}],"container-title":["Biological Psychiatry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322325015811?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0006322325015811?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T00:25:36Z","timestamp":1783729536000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0006322325015811"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":42,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,7]]}},"alternative-id":["S0006322325015811"],"URL":"https:\/\/doi.org\/10.1016\/j.biopsych.2025.10.032","relation":{},"ISSN":["0006-3223"],"issn-type":[{"value":"0006-3223","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Mapping DNA Methylation Signatures to Identify Epigenetic Variation Across Subcortical Regions of the Human Posttraumatic Stress Disorder Brain","name":"articletitle","label":"Article Title"},{"value":"Biological Psychiatry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biopsych.2025.10.032","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Published by Elsevier Inc on behalf of Society of Biological Psychiatry.","name":"copyright","label":"Copyright"}]}}