{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T17:54:25Z","timestamp":1792086865634,"version":"4.4.0"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100013253","name":"Open Research Fund of Key Laboratory of Digital Earth Science","doi-asserted-by":"publisher","award":["2019B030301008"],"award-info":[{"award-number":["2019B030301008"]}],"id":[{"id":"10.13039\/501100013253","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022963","name":"Key Research and Development Program of Zhejiang Province","doi-asserted-by":"publisher","award":["2020YFC1806901"],"award-info":[{"award-number":["2020YFC1806901"]}],"id":[{"id":"10.13039\/100022963","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010012","name":"National Aerospace Science Foundation of China","doi-asserted-by":"publisher","award":["42277382"],"award-info":[{"award-number":["42277382"]}],"id":[{"id":"10.13039\/501100010012","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010012","name":"National Aerospace Science Foundation of China","doi-asserted-by":"publisher","award":["42030703"],"award-info":[{"award-number":["42030703"]}],"id":[{"id":"10.13039\/501100010012","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010012","name":"National Aerospace Science Foundation of China","doi-asserted-by":"publisher","award":["21806044"],"award-info":[{"award-number":["21806044"]}],"id":[{"id":"10.13039\/501100010012","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100020730","name":"Department of Natural Resources of Guangdong Province","doi-asserted-by":"publisher","award":["2023A1515011526"],"award-info":[{"award-number":["2023A1515011526"]}],"id":[{"id":"10.13039\/100020730","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioresource Technology"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.biortech.2024.131297","type":"journal-article","created":{"date-parts":[[2024,8,15]],"date-time":"2024-08-15T15:34:03Z","timestamp":1723736043000},"page":"131297","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":15,"special_numbering":"C","title":["Aerobic granular sludge for swine wastewater treatment: Implications for antibiotic and antibiotic resistance gene elimination"],"prefix":"10.1016","volume":"410","author":[{"given":"Meng-Yuan","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Run-Dong","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuang-Shuang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheng-Lei","family":"Pei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liang-Ying","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian-Liang","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"You-Sheng","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Jing","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guang-Guo","family":"Ying","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.biortech.2024.131297_b0005","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.watres.2013.10.043","article-title":"Performance of aerobic granular sludge in a sequencing batch bioreactor exposed to ofloxacin, norfloxacin and ciprofloxacin","volume":"50","author":"Amorim","year":"2014","journal-title":"Water Res."},{"issue":"17","key":"10.1016\/j.biortech.2024.131297_b0010","doi-asserted-by":"crossref","first-page":"2882","DOI":"10.1093\/bioinformatics\/btv287","article-title":"Tax4Fun: predicting functional profiles from metagenomic 16S rRNA data","volume":"31","author":"Asshauer","year":"2015","journal-title":"Bioinformatics"},{"key":"10.1016\/j.biortech.2024.131297_b0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.150737","article-title":"Application of metagenomics to biological wastewater treatment","volume":"807","author":"Chen","year":"2022","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.biortech.2024.131297_b0020","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/j.biortech.2017.04.023","article-title":"Removal of antibiotics from piggery wastewater by biological aerated filter system: Treatment efficiency and biodegradation kinetics","volume":"238","author":"Chen","year":"2017","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2024.131297_b0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2023.128606","article-title":"Swine wastewater treatment using combined up-flow anaerobic sludge blanket and anaerobic membrane bioreactor: Performance and microbial community diversity","volume":"373","author":"Chen","year":"2023","journal-title":"Bioresour. Technol."},{"issue":"4","key":"10.1016\/j.biortech.2024.131297_b0030","doi-asserted-by":"crossref","first-page":"2205","DOI":"10.1007\/s10661-011-2110-y","article-title":"Occurrence and dissipation of veterinary antibiotics in two typical swine wastewater treatment systems in east China","volume":"184","author":"Chen","year":"2012","journal-title":"Environ. Monit. Assess."},{"key":"10.1016\/j.biortech.2024.131297_b0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2023.129606","article-title":"Metagenomics insights into high-rate nitrogen removal from municipal wastewater by integrated nitrification, partial denitrification and Anammox at an extremely short hydraulic retention time","volume":"387","author":"Chen","year":"2023","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2024.131297_b0040","doi-asserted-by":"crossref","first-page":"1664","DOI":"10.1016\/j.scitotenv.2017.10.059","article-title":"Bioprocessing for elimination antibiotics and hormones from swine wastewater","volume":"621","author":"Cheng","year":"2018","journal-title":"Sci. Total Environ."},{"issue":"2","key":"10.1016\/j.biortech.2024.131297_b0045","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.1111\/jam.15267","article-title":"Effects of sulfamethoxazole on aerobic sludge granulation process","volume":"132","author":"Cui","year":"2022","journal-title":"J. Appl. Microbiol."},{"key":"10.1016\/j.biortech.2024.131297_b0050","series-title":"Standard methods for the examination of water and wastewater","author":"Eaton","year":"2005"},{"issue":"10","key":"10.1016\/j.biortech.2024.131297_b0055","doi-asserted-by":"crossref","first-page":"996","DOI":"10.1038\/nmeth.2604","article-title":"UPARSE: Highly accurate OTU sequences from microbial amplicon reads","volume":"10","author":"Edgar","year":"2013","journal-title":"Nat. Methods"},{"key":"10.1016\/j.biortech.2024.131297_b0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.140482","article-title":"Untreated swine wastes changed antibiotic resistance and microbial community in the soils and impacted abundances of antibiotic resistance genes in the vegetables","volume":"741","author":"Gao","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.biortech.2024.131297_b0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2019.122280","article-title":"Research on the aerobic granular sludge under alkalinity in sequencing batch reactors: Removal efficiency, metagenomic and key microbes","volume":"296","author":"Gao","year":"2020","journal-title":"Bioresour. Technol."},{"issue":"3","key":"10.1016\/j.biortech.2024.131297_b0070","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1101\/gr.112730.110","article-title":"Chimeric 16S rRNA sequence formation and detection in Sanger and 454-pyrosequenced PCR amplicons","volume":"21","author":"Haas","year":"2011","journal-title":"Genome Res."},{"key":"10.1016\/j.biortech.2024.131297_b0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2019.136094","article-title":"Removal of veterinary antibiotics from swine wastewater using anaerobic and aerobic biodegradation","volume":"709","author":"Han","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.biortech.2024.131297_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2022.116065","article-title":"Emerging technologies for enhanced removal of residual antibiotics from source-separated urine and wastewaters: A review","volume":"322","author":"Imwene","year":"2022","journal-title":"J. Environ. Manage."},{"key":"10.1016\/j.biortech.2024.131297_b0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.jenvman.2022.114706","article-title":"Role of initial bacterial community in the aerobic sludge granulation and performance","volume":"309","author":"Jin","year":"2022","journal-title":"J. Environ. Manage."},{"key":"10.1016\/j.biortech.2024.131297_b0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105540","article-title":"Emergence and spread patterns of antibiotic resistance genes during two different aerobic granular sludge cultivation processes","volume":"137","author":"Li","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.biortech.2024.131297_b0095","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.biortech.2016.03.008","article-title":"The effect and biological mechanism of COD\/TN ratio on nitrogen removal in a novel upflow microaerobic sludge reactor treating manure-free piggery wastewater","volume":"209","author":"Li","year":"2016","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2024.131297_b0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2022.137508","article-title":"Biotransformation of sulfamonomethoxine in a granular sludge system: Pathways and mechanisms","volume":"313","author":"Li","year":"2023","journal-title":"Chemosphere"},{"key":"10.1016\/j.biortech.2024.131297_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.111885","article-title":"Removal of antibiotic resistance genes from swine wastewater by membrane filtration treatment","volume":"210","author":"Liang","year":"2021","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.biortech.2024.131297_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.143981","article-title":"Interaction between tetracycline and microorganisms during wastewater treatment: A review","volume":"757","author":"Liao","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.biortech.2024.131297_b0115","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.biortech.2014.10.123","article-title":"Dynamics of bacterial microbiota during lignocellulosic waste composting: Studies upon its structure, functionality and biodiversity","volume":"175","author":"Lopez-Gonzalez","year":"2015","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2024.131297_b0120","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.watres.2014.05.037","article-title":"Impact of influent COD\/N ratio on disintegration of aerobic granular sludge","volume":"62","author":"Luo","year":"2014","journal-title":"Water Res."},{"key":"10.1016\/j.biortech.2024.131297_b0125","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1016\/j.cej.2017.10.051","article-title":"Long-term low dissolved oxygen accelerates the removal of antibiotics and antibiotic resistance genes in swine wastewater treatment","volume":"334","author":"Ma","year":"2018","journal-title":"Chem. Eng. J."},{"issue":"8","key":"10.1016\/j.biortech.2024.131297_b0130","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.1016\/j.procbio.2013.06.004","article-title":"Operation of an aerobic granular pilot scale SBR plant to treat swine slurry","volume":"48","author":"Morales","year":"2013","journal-title":"Process Biochem."},{"issue":"23","key":"10.1016\/j.biortech.2024.131297_b0135","doi-asserted-by":"crossref","first-page":"6557","DOI":"10.1039\/c3ay41160e","article-title":"Fluorescence spectroscopy and multi-way techniques","volume":"5","author":"Murphy","year":"2013","journal-title":"PARAFAC. Anal. Method."},{"issue":"13","key":"10.1016\/j.biortech.2024.131297_b0140","doi-asserted-by":"crossref","first-page":"7234","DOI":"10.1021\/acs.est.9b01131","article-title":"Insights into the fate and removal of antibiotics in engineered biological treatment systems: A critical review","volume":"53","author":"Oberoi","year":"2019","journal-title":"Environ. Sci. Technol."},{"issue":"16","key":"10.1016\/j.biortech.2024.131297_b0145","doi-asserted-by":"crossref","first-page":"8473","DOI":"10.1021\/acs.est.6b00053","article-title":"Predicting sources of dissolved organic nitrogen to an estuary from an agro-urban coastal watershed","volume":"50","author":"Osburn","year":"2016","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.biortech.2024.131297_b0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2023.120702","article-title":"From micro to macro: The role of seawater in maintaining structural integrity and bioactivity of granules in treating antibiotic-laden mariculture wastewater","volume":"246","author":"Qian","year":"2023","journal-title":"Water Res."},{"key":"10.1016\/j.biortech.2024.131297_b0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2021.125527","article-title":"Responses of aerobic granular sludge to fluoroquinolones: Microbial community variations, and antibiotic resistance genes","volume":"414","author":"Shi","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.biortech.2024.131297_b0160","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.envint.2018.06.008","article-title":"Does the biological treatment or membrane separation reduce the antibiotic resistance genes from swine wastewater through a sequencing-batch membrane bioreactor treatment process","volume":"118","author":"Sui","year":"2018","journal-title":"Environ. Int."},{"key":"10.1016\/j.biortech.2024.131297_b0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.167031","article-title":"Antibiotics resistance removal from piggery wastewater by an integrated anaerobic\u2013aerobic biofilm reactor: Efficiency and mechanism","volume":"905","author":"Tang","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.biortech.2024.131297_b0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2022.140265","article-title":"Antibiotics removal from piggery wastewater by a novel aerobic-microaerobic system: Efficiency and mechanism","volume":"454","author":"Tian","year":"2023","journal-title":"Chem. Eng. J."},{"issue":"3","key":"10.1016\/j.biortech.2024.131297_b0175","doi-asserted-by":"crossref","first-page":"1129","DOI":"10.1016\/j.watres.2010.11.008","article-title":"Biodiversity and population dynamics of microorganisms in a full-scale membrane bioreactor for municipal wastewater treatment","volume":"45","author":"Wan","year":"2011","journal-title":"Water Res."},{"key":"10.1016\/j.biortech.2024.131297_b0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2020.127544","article-title":"Effect of carbon source on pollutant removal and microbial community dynamics in treatment of swine wastewater containing antibiotics by aerobic granular sludge","volume":"260","author":"Wang","year":"2020","journal-title":"Chemosphere"},{"key":"10.1016\/j.biortech.2024.131297_b0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.124762","article-title":"The performance of aerobic granular sludge for simulated swine wastewater treatment and the removal mechanism of tetracycline","volume":"408","author":"Wang","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.biortech.2024.131297_b0190","article-title":"Hormesis effects of sulfadiazine on aerobic granular sludge at decreasing temperature: Granulation, performance, microbial community and antibiotic resistance","volume":"430","author":"Wang","year":"2022","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.biortech.2024.131297_b0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2020.105897","article-title":"Dominant denitrifying bacteria are important hosts of antibiotic resistance genes in pig farm anoxic-oxic wastewater treatment processes","volume":"143","author":"Yang","year":"2020","journal-title":"Environ. Int."},{"key":"10.1016\/j.biortech.2024.131297_b0200","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1021\/acsestwater.1c00427","article-title":"Lanthanum (III)-coated ceramic filters in point-of-use water treatment for bacterial removal","volume":"2","author":"Yang","year":"2022","journal-title":"ACS ES&T Water"},{"key":"10.1016\/j.biortech.2024.131297_b0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.122583","article-title":"Enhancement of PPCPs removal by shaped microbial community of aerobic granular sludge under condition of low C\/N ratio influent","volume":"394","author":"Yu","year":"2020","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.biortech.2024.131297_b0210","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1016\/j.biortech.2018.10.048","article-title":"Impact of ampicillin on the nitrogen removal, microbial community and enzymatic activity of activated sludge","volume":"272","author":"Yu","year":"2019","journal-title":"Bioresour. Technol."},{"issue":"11","key":"10.1016\/j.biortech.2024.131297_b0215","doi-asserted-by":"crossref","first-page":"6476","DOI":"10.1021\/acs.est.8b00568","article-title":"Understanding the role of extracellular polymeric substances on ciprofloxacin adsorption in aerobic sludge, anaerobic sludge and sulfate-reducing bacteria sludge systems","volume":"52","author":"Zhang","year":"2018","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.biortech.2024.131297_b0220","doi-asserted-by":"crossref","DOI":"10.1016\/j.bej.2021.108204","article-title":"Correlation between polyhydroxyalkanoates and extracellular polymeric substances in the activated sludge biosystems with different carbon to nitrogen ratio","volume":"176","author":"Zhao","year":"2021","journal-title":"Biochem. Eng. J."},{"key":"10.1016\/j.biortech.2024.131297_b0225","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1016\/j.chroma.2012.04.076","article-title":"Simultaneous determination of human and veterinary antibiotics in various environmental matrices by rapid resolution liquid chromatography-electrospray ionization tandem mass spectrometry","volume":"1244","author":"Zhou","year":"2012","journal-title":"J. Chromatogr. a."}],"container-title":["Bioresource Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960852424010010?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960852424010010?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T20:43:30Z","timestamp":1725569010000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960852424010010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":45,"alternative-id":["S0960852424010010"],"URL":"https:\/\/doi.org\/10.1016\/j.biortech.2024.131297","relation":{},"ISSN":["0960-8524"],"issn-type":[{"value":"0960-8524","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Aerobic granular sludge for swine wastewater treatment: Implications for antibiotic and antibiotic resistance gene elimination","name":"articletitle","label":"Article Title"},{"value":"Bioresource Technology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biortech.2024.131297","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"131297"}}