{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T04:08:13Z","timestamp":1793333293704,"version":"4.5.0"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100019336","name":"Key Research and Development Plan of Tianjin","doi-asserted-by":"publisher","award":["24YFXTHZ00260"],"award-info":[{"award-number":["24YFXTHZ00260"]}],"id":[{"id":"10.13039\/501100019336","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin Municipality","doi-asserted-by":"publisher","award":["24JCZDJC01150"],"award-info":[{"award-number":["24JCZDJC01150"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioresource Technology"],"published-print":{"date-parts":[[2026,2]]},"DOI":"10.1016\/j.biortech.2025.133645","type":"journal-article","created":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T09:11:38Z","timestamp":1763111498000},"page":"133645","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["Transcriptomic insights into dynamically optimized batch feeding strategies for carbon fixation mechanisms in CO2 absorption-microalgae conversion system"],"prefix":"10.1016","volume":"441","author":[{"given":"Yaoqi","family":"Hou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yizhen","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dantong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zezhou","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhan","family":"Hu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yutaka","family":"Kitamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunfeng","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biortech.2025.133645_b0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.energy.2022.126565","article-title":"Causality analysis of the impacts of petroleum use, economic growth, and technological innovation on carbon emissions in Bangladesh","volume":"267","author":"Chen","year":"2023","journal-title":"Energy"},{"key":"10.1016\/j.biortech.2025.133645_b0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2021.130884","article-title":"Biologically-mediated carbon capture and utilization by microalgae towards sustainable CO2 biofixation and biomass valorization \u2013 a review","volume":"427","author":"Daneshvar","year":"2022","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.biortech.2025.133645_b0015","article-title":"Statistical review of world energy","author":"Davenport","year":"2023","journal-title":"Energy Institute."},{"key":"10.1016\/j.biortech.2025.133645_b0020","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2021.126304","article-title":"Microalgae-based carbohydrates: a green innovative source of bioenergy","volume":"344","author":"De Carvalho Silvello","year":"2022","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2025.133645_b0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.rser.2021.111464","article-title":"Microalgae: Sustainable resource of carbohydrates in third-generation biofuel production","volume":"150","author":"Debnath","year":"2021","journal-title":"Renew. Sustainable Energy Rev."},{"key":"10.1016\/j.biortech.2025.133645_b0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2022.126900","article-title":"Promoting effect of plant hormone gibberellin on co-metabolism of sulfamethoxazole by microalgae Chlorella pyrenoidosa","volume":"351","author":"Gao","year":"2022","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2025.133645_b0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.130435","article-title":"Enhancing microalgae growth and product accumulation with carbon source regulation: New perspective for the coordination between photosynthesis and aerobic respiration","volume":"278","author":"Gao","year":"2021","journal-title":"Chemosphere"},{"key":"10.1016\/j.biortech.2025.133645_b0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.enpol.2023.113469","article-title":"Overcoming the shock of energy depletion for energy policy? Tracing the missing link between energy depletion, renewable energy development and decarbonization in the USA","volume":"174","author":"Hossain","year":"2023","journal-title":"Energy Policy"},{"key":"10.1016\/j.biortech.2025.133645_b0045","article-title":"Coupling attached cultivation with CO2 absorption-microalgae conversion system for efficient bio-integrated carbon capture and utilization","volume":"132933","author":"Hou","year":"2025","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2025.133645_b0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2023.115392","article-title":"Role of secondary metabolites in distressed microalgae","volume":"224","author":"Kolackova","year":"2023","journal-title":"Environ. Res."},{"key":"10.1016\/j.biortech.2025.133645_b0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.rser.2025.116025","article-title":"Upgrading microalgae for petroleum alternatives: CO2 upcycling for photosynthesis-based society","volume":"222","author":"Lee","year":"2025","journal-title":"Renew. Sustainable Energy Rev."},{"key":"10.1016\/j.biortech.2025.133645_b0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.energy.2024.133047","article-title":"Phytohormones enhanced carbon fixation and biomass production in CO2 absorption-microalgae conversion system under light stress","volume":"308","author":"Li","year":"2024","journal-title":"Energy"},{"key":"10.1016\/j.biortech.2025.133645_b0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2020.123126","article-title":"Effect of different nitrogen ratio on the performance of CO2 absorption and microalgae conversion (CAMC) hybrid system","volume":"306","author":"Li","year":"2020","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2025.133645_b0070","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1002\/bit.24595","article-title":"The microalga Parachlorella kessleri \u2013\u2013a novel highly efficient lipid producer","volume":"110","author":"Li","year":"2013","journal-title":"Biotechnol. Bioeng."},{"key":"10.1016\/j.biortech.2025.133645_b0075","doi-asserted-by":"crossref","first-page":"583","DOI":"10.1016\/j.biortech.2017.11.086","article-title":"Physiological-phased kinetic characteristics of microalgae Chlorella vulgaris growth and lipid synthesis considering synergistic effects of light, carbon and nutrients","volume":"250","author":"Liao","year":"2018","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2025.133645_b0080","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1016\/j.sajb.2021.02.028","article-title":"Effects of organic carbon sources on the biomass and lipid production by the novel microalga Micractinium reisseri FM1 under batch and fed-batch cultivation","volume":"139","author":"Liu","year":"2021","journal-title":"South Afr. J. Bot."},{"key":"10.1016\/j.biortech.2025.133645_b0085","doi-asserted-by":"crossref","first-page":"56","DOI":"10.3390\/biology3010056","article-title":"Polar Microalgae: New Approaches towards Understanding Adaptations to an Extreme and changing Environment","volume":"3","author":"Lyon","year":"2014","journal-title":"Biology"},{"key":"10.1016\/j.biortech.2025.133645_b0090","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1021\/acssuschemeng.3c04955","article-title":"Effect of DACH-K2CO3 mixed absorbent on the performance of a CO2 absorption and microalgae conversion (CAMC) system","volume":"12","author":"Mao","year":"2024","journal-title":"ACS Sustain. Chem. Eng."},{"key":"10.1016\/j.biortech.2025.133645_b0095","doi-asserted-by":"crossref","first-page":"2758","DOI":"10.1007\/s12010-014-0727-3","article-title":"Effect of Various Colors of Light-Emitting Diodes (LEDs) on the Biomass Composition of Arthrospira platensis Cultivated in Semi-continuous Mode","volume":"172","author":"Markou","year":"2014","journal-title":"Appl. Biochem. Biotechnol."},{"key":"10.1016\/j.biortech.2025.133645_b0100","doi-asserted-by":"crossref","first-page":"1532","DOI":"10.1016\/j.biotechadv.2013.07.011","article-title":"Microalgae for high-value compounds and biofuels production: a review with focus on cultivation under stress conditions","volume":"31","author":"Markou","year":"2013","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.biortech.2025.133645_b0105","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.biortech.2003.09.002","article-title":"Chlorophyll production from Spirulina platensis\u202f: cultivation with urea addition by fed-batch process","volume":"92","author":"Rangel-Yagui","year":"2004","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2025.133645_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2021.149791","article-title":"Performance intensification of CO2 absorption and microalgae conversion (CAMC) hybrid system via low temperature plasma (LTP) treatment","volume":"801","author":"Song","year":"2021","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.biortech.2025.133645_b0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.ijggc.2019.01.001","article-title":"Intensification of a novel absorption-microalgae hybrid CO2 utilization process via fed-batch mode optimization","volume":"82","author":"Song","year":"2019","journal-title":"Int. J. Greenhouse Gas Control"},{"key":"10.1016\/j.biortech.2025.133645_b0120","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1016\/j.psep.2022.02.064","article-title":"Removal of cefradine by chlorella sp. L166 and scenedesmus quadricauda: toxicity investigation, degradation mechanism and metabolic pathways","volume":"160","author":"Wang","year":"2022","journal-title":"Process Saf. Environ. Prot."},{"key":"10.1016\/j.biortech.2025.133645_b0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.energy.2023.129614","article-title":"Cyclic stability evaluation of a novel CO2 absorption-microalgae conversion (CAMC) system","volume":"286","author":"Wang","year":"2024","journal-title":"Energy"},{"key":"10.1016\/j.biortech.2025.133645_b0130","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.procbio.2017.05.027","article-title":"A two-stage fed-batch heterotrophic culture of Chlorella protothecoides that combined nitrogen depletion with hyperosmotic stress strategy enhanced lipid yield and productivity","volume":"60","author":"Wang","year":"2017","journal-title":"Process Biochem."},{"key":"10.1016\/j.biortech.2025.133645_b0135","article-title":"Decarbonizing the Coal-Fired Power Sector in China via Carbon Capture, Geological utilization, and Storage Technology","volume":"acs.est.1c01144","author":"Wei","year":"2021","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.biortech.2025.133645_b0140","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/j.biortech.2016.01.038","article-title":"Biodegradation of carbamazepine using freshwater microalgae Chlamydomonas mexicana and Scenedesmus obliquus and the determination of its metabolic fate","volume":"205","author":"Xiong","year":"2016","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2025.133645_b0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclepro.2023.136175","article-title":"Boosting the yields of microalgal biomass and high-value added products by phytohormones: a mechanistic insight using transcriptomics","volume":"393","author":"Xu","year":"2023","journal-title":"J. Clean. Prod."},{"key":"10.1016\/j.biortech.2025.133645_b0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2019.122402","article-title":"Fed-batch fermentation of mixed carbon source significantly enhances the production of docosahexaenoic acid in Thraustochytriidae sp. PKU#Mn16 by differentially regulating fatty acids biosynthetic pathways","volume":"297","author":"Ye","year":"2020","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2025.133645_b0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2021.125648","article-title":"A fed-batch feeding with succinic acid strategy for astaxanthin and lipid hyper-production in Haematococcus pluviualis","volume":"340","author":"Yu","year":"2021","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2025.133645_b0160","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.bej.2016.05.002","article-title":"Metabolomics analysis of phytohormone gibberellin improving lipid and DHA accumulation in Aurantiochytrium sp","volume":"112","author":"Yu","year":"2016","journal-title":"Biochem. Eng. J."},{"key":"10.1016\/j.biortech.2025.133645_b0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.jksus.2021.101433","article-title":"Transcriptome analysis revealed transporter proteins role in the growth of Labrenzia sp. PO1 and SY1","volume":"33","author":"Zaynab","year":"2021","journal-title":"J. King Saud Univ. Sci."},{"key":"10.1016\/j.biortech.2025.133645_b0170","doi-asserted-by":"crossref","DOI":"10.3389\/fpls.2023.1278954","article-title":"The RNA landscape of Dunaliella salina in response to short-term salt stress","volume":"14","author":"Zhang","year":"2023","journal-title":"Front. Plant Sci."}],"container-title":["Bioresource Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960852425016128?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960852425016128?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T13:29:15Z","timestamp":1768397355000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960852425016128"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,2]]},"references-count":34,"alternative-id":["S0960852425016128"],"URL":"https:\/\/doi.org\/10.1016\/j.biortech.2025.133645","relation":{},"ISSN":["0960-8524"],"issn-type":[{"value":"0960-8524","type":"print"}],"subject":[],"published":{"date-parts":[[2026,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Transcriptomic insights into dynamically optimized batch feeding strategies for carbon fixation mechanisms in CO2 absorption-microalgae conversion system","name":"articletitle","label":"Article Title"},{"value":"Bioresource Technology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biortech.2025.133645","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"133645"}}