{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T06:51:38Z","timestamp":1776927098791,"version":"3.51.2"},"reference-count":69,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100020950","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC 114-2622-E-992-013 -"],"award-info":[{"award-number":["NSTC 114-2622-E-992-013 -"]}],"id":[{"id":"10.13039\/501100020950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100020950","name":"National Science and Technology Council","doi-asserted-by":"publisher","award":["NSTC 113-2622-E-992-014 -"],"award-info":[{"award-number":["NSTC 113-2622-E-992-014 -"]}],"id":[{"id":"10.13039\/501100020950","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["113\\u20132622-E-992\\u2013014"],"award-info":[{"award-number":["113\\u20132622-E-992\\u2013014"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004663","name":"Ministry of Science and Technology, Taiwan","doi-asserted-by":"publisher","award":["114\\u20132622-E-992\\u2013013"],"award-info":[{"award-number":["114\\u20132622-E-992\\u2013013"]}],"id":[{"id":"10.13039\/501100004663","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioresource Technology"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.biortech.2026.134588","type":"journal-article","created":{"date-parts":[[2026,4,8]],"date-time":"2026-04-08T07:39:17Z","timestamp":1775633957000},"page":"134588","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Circular bioprocessing of bovine blood for peptide-based antimicrobial and antibiofilm agents"],"prefix":"10.1016","volume":"452","author":[{"ORCID":"https:\/\/orcid.org\/0009-0006-0436-7805","authenticated-orcid":false,"given":"Gan","family":"Huey","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asif Ali","family":"Bhat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bao-Hong","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5830-8591","authenticated-orcid":false,"given":"Ming\u2010Kuei","family":"Shih","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7244-3287","authenticated-orcid":false,"given":"Li-Jung","family":"Yin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"You-Lin","family":"Tain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-Wei","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4313-8018","authenticated-orcid":false,"given":"Yeu-Ching","family":"Shi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8007-6077","authenticated-orcid":false,"given":"Chih-Yao","family":"Hou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.biortech.2026.134588_b0005","doi-asserted-by":"crossref","first-page":"268","DOI":"10.3390\/membranes10100268","article-title":"Bovine hemoglobin enzymatic hydrolysis by a new eco-efficient process-part II: production of bioactive peptides","volume":"10","author":"Abou-Diab","year":"2020","journal-title":"Membranes (Basel)"},{"key":"10.1016\/j.biortech.2026.134588_b0010","doi-asserted-by":"crossref","first-page":"257","DOI":"10.3390\/membranes10100257","article-title":"Bovine hemoglobin enzymatic hydrolysis by a new ecoefficient process\u2014part I: feasibility of electrodialysis with bipolar membrane and production of neokyotorphin (\u03b1137-141)","volume":"10","author":"Abou-Diab","year":"2020","journal-title":"Membranes (Basel)"},{"key":"10.1016\/j.biortech.2026.134588_b0015","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/j.ijbiomac.2011.04.004","article-title":"Obtaining antimicrobial peptides by controlled peptic hydrolysis of bovine hemoglobin","volume":"49","author":"Adje","year":"2011","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biortech.2026.134588_b0020","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.biotechadv.2011.01.001","article-title":"Industrial-scale manufacturing of pharmaceutical-grade bioactive peptides","volume":"29","author":"Agyei","year":"2011","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.biortech.2026.134588_b0025","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1016\/j.tifs.2022.11.024","article-title":"Purification and fractionation of bioactive peptides through membrane filtration: a critical and application review","volume":"131","author":"Alavi","year":"2023","journal-title":"Trends Food Sci. Technol."},{"key":"10.1016\/j.biortech.2026.134588_b0030","doi-asserted-by":"crossref","DOI":"10.3389\/fsufs.2024.1410640","article-title":"Review of the slaughter wastes and the meat by-products recycling opportunities","volume":"8","author":"Alibekov","year":"2024","journal-title":"Front. Sustain. Food Syst."},{"key":"10.1016\/j.biortech.2026.134588_b0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.resconrec.2025.108571","article-title":"A literature review of slaughterhouse waste valorisation: techniques, environmental, and economic implications","volume":"224","author":"Ashilenje","year":"2026","journal-title":"Resour. Conserv. Recycl."},{"key":"10.1016\/j.biortech.2026.134588_b0040","doi-asserted-by":"crossref","first-page":"3905","DOI":"10.1002\/pmic.201000288","article-title":"Labeling elastase digests with TMT: informational gain by identification of poorly detectable peptides with MALDI\u2010TOF\/TOF mass spectrometry","volume":"10","author":"Baeumlisberger","year":"2010","journal-title":"Proteomics"},{"key":"10.1016\/j.biortech.2026.134588_b0045","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/j.foodchem.2016.02.020","article-title":"Production of bioactive peptide hydrolysates from deer, sheep, pig and cattle red blood cell fractions using plant and fungal protease preparations","volume":"202","author":"Bah","year":"2016","journal-title":"Food Chem."},{"key":"10.1016\/j.biortech.2026.134588_b0050","article-title":"Edible domestic animal blood products for biomedical and disease treatment applications","volume":"100308","author":"Cao","year":"2025","journal-title":"Curr. Res. Biotechnol."},{"key":"10.1016\/j.biortech.2026.134588_b0055","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2021.126065","article-title":"Advances in solid-state fermentation for bioconversion of agricultural wastes to value-added products: opportunities and challenges","volume":"343","author":"Chilakamarry","year":"2022","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2026.134588_b0060","doi-asserted-by":"crossref","first-page":"477","DOI":"10.3390\/pathogens12030477","article-title":"Bioactive antimicrobial peptides from food proteins: perspectives and challenges for controlling foodborne pathogens","volume":"12","author":"Corr\u00eaa","year":"2023","journal-title":"Pathogens"},{"key":"10.1016\/j.biortech.2026.134588_b0065","doi-asserted-by":"crossref","first-page":"463","DOI":"10.3390\/antibiotics10040463","article-title":"Rapid screening of essential oils as substances which enhance antibiotic activity using a modified well diffusion method","volume":"10","author":"Cui","year":"2021","journal-title":"Antibiotics"},{"key":"10.1016\/j.biortech.2026.134588_b0070","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1004152","article-title":"Broad-spectrum anti-biofilm peptide that targets a cellular stress response","volume":"10","author":"De la Fuente-N\u00fa\u00f1ez","year":"2014","journal-title":"PLoS Pathog."},{"key":"10.1016\/j.biortech.2026.134588_b0075","doi-asserted-by":"crossref","first-page":"196","DOI":"10.1016\/j.chembiol.2015.01.002","article-title":"D-enantiomeric peptides that eradicate wild-type and multidrug-resistant biofilms and protect against lethal Pseudomonas aeruginosa infections","volume":"22","author":"De La Fuente-N\u00fa\u00f1ez","year":"2015","journal-title":"Chem. Biol."},{"key":"10.1016\/j.biortech.2026.134588_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.afres.2022.100253","article-title":"Coffee fermentation: expedition from traditional to controlled process and perspectives for industrialization","volume":"3","author":"Elhalis","year":"2023","journal-title":"Appl. Food Res."},{"key":"10.1016\/j.biortech.2026.134588_b0085","doi-asserted-by":"crossref","first-page":"25330","DOI":"10.1074\/jbc.274.36.25330","article-title":"Antimicrobial activity of a bovine hemoglobin fragment in the tick Boophilus microplus","volume":"274","author":"Fogaca","year":"1999","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.biortech.2026.134588_b0090","article-title":"Unveiling mechanisms of antimicrobial peptide: actions beyond the membranes disruption","volume":"10","author":"Gagandeep","year":"2024","journal-title":"Heliyon"},{"key":"10.1016\/j.biortech.2026.134588_b0095","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.ijfoodmicro.2007.06.001","article-title":"Bacteriocin-based strategies for food biopreservation","volume":"120","author":"G\u00e1lvez","year":"2007","journal-title":"Int. J. Food Microbiol."},{"key":"10.1016\/j.biortech.2026.134588_b0100","doi-asserted-by":"crossref","first-page":"339","DOI":"10.2174\/0929866526666190228144219","article-title":"Applicability of instability index for in vitro protein stability prediction","volume":"26","author":"Gamage","year":"2019","journal-title":"Protein Pept. Lett."},{"key":"10.1016\/j.biortech.2026.134588_b0105","doi-asserted-by":"crossref","first-page":"2993","DOI":"10.3389\/fmicb.2019.02993","article-title":"The fungal cell wall: Candida, Cryptococcus, and Aspergillus species","volume":"10","author":"Garcia-Rubio","year":"2020","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.biortech.2026.134588_b0110","doi-asserted-by":"crossref","first-page":"8","DOI":"10.3390\/foods14010008","article-title":"Antimicrobial peptides from porcine blood cruor hydrolysates as a promising source of antifungal activity","volume":"14","author":"Garc\u00eda-Vela","year":"2024","journal-title":"Foods"},{"key":"10.1016\/j.biortech.2026.134588_b0115","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1016\/j.biortech.2017.12.062","article-title":"Enzymatic saccharification of lignocellulosic biorefinery: research focuses","volume":"252","author":"Guo","year":"2018","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2026.134588_b0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2023.105422","article-title":"Bioactive peptides derived from fermented foods: preparation and biological activities","volume":"101","author":"Guo","year":"2023","journal-title":"J. Funct. Foods"},{"key":"10.1016\/j.biortech.2026.134588_b0125","doi-asserted-by":"crossref","first-page":"1008","DOI":"10.1038\/nbt1113","article-title":"High-throughput generation of small antibacterial peptides with improved activity","volume":"23","author":"Hilpert","year":"2005","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.biortech.2026.134588_b0130","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1007\/s11274-010-0514-4","article-title":"Isolation and characterization of an antimicrobial peptide from bovine hemoglobin \u03b1-subunit","volume":"27","author":"Hu","year":"2011","journal-title":"World J. Microbiol. Biotechnol."},{"key":"10.1016\/j.biortech.2026.134588_b0135","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1016\/j.indcrop.2017.08.025","article-title":"Antioxidant, antityrosinase and antibiofilm activities of synthesized peptides derived from Vicia faba protein hydrolysate: a powerful agents in cosmetic application","volume":"109","author":"Karkouch","year":"2017","journal-title":"Ind. Crop. Prod."},{"key":"10.1016\/j.biortech.2026.134588_b0140","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s13197-022-05606-x","article-title":"Evaluation of the antimicrobial attribute of bioactive peptides derived from colostrum whey fermented by Lactobacillus against diarrheagenic E. coli strains","volume":"60","author":"Kashyap","year":"2023","journal-title":"J. Food Sci. Technol."},{"key":"10.1016\/j.biortech.2026.134588_b0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.jff.2022.105158","article-title":"Identification of antibacterial and immunomodulatory bioactive peptides generated from buffalo (Bubalus bubalis) colostrum whey fermented by Lactobacillus rhamnosus C25: LC-MS\/MS-based analysis","volume":"95","author":"Kashyap","year":"2022","journal-title":"J. Funct. Foods"},{"key":"10.1016\/j.biortech.2026.134588_b0150","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.ijbiomac.2022.08.087","article-title":"Antimicrobial, anti-biofilm, antioxidant and cytotoxic effects of bacteriocin by Lactococcus lactis strain CH3 isolated from fermented dairy products\u2014an in vitro and in silico approach","volume":"220","author":"Krishnamoorthi","year":"2022","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biortech.2026.134588_b0155","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.smallrumres.2016.05.002","article-title":"Antioxidant and antimicrobial activity of camel milk casein hydrolysates and its fractions","volume":"139","author":"Kumar","year":"2016","journal-title":"Small Rumin. Res."},{"key":"10.1016\/j.biortech.2026.134588_b0160","doi-asserted-by":"crossref","first-page":"2733","DOI":"10.3168\/jds.S0022-0302(02)74360-9","article-title":"Immunomodulating effects of peptidic fractions issued from milk fermented with Lactobacillus helveticus","volume":"85","author":"LeBlanc","year":"2002","journal-title":"J. Dairy Sci."},{"key":"10.1016\/j.biortech.2026.134588_b0165","doi-asserted-by":"crossref","first-page":"73","DOI":"10.3389\/fnins.2017.00073","article-title":"Membrane active antimicrobial peptides: translating mechanistic insights to design","volume":"11","author":"Li","year":"2017","journal-title":"Front. Neurosci."},{"key":"10.1016\/j.biortech.2026.134588_b0170","doi-asserted-by":"crossref","first-page":"7460","DOI":"10.1021\/acs.jafc.2c02699","article-title":"Harsh sensitivity and mechanism exploration of an antibacterial peptide extracted from walnut oil residue derived from agro-industrial waste","volume":"70","author":"Liu","year":"2022","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.biortech.2026.134588_b0175","doi-asserted-by":"crossref","first-page":"95","DOI":"10.3390\/fermentation11020095","article-title":"Probiotic potential of lactic acid bacteria and yeast isolated from cocoa and coffee bean fermentation: a review","volume":"11","author":"L\u00f3pez-Palestino","year":"2025","journal-title":"Fermentation"},{"key":"10.1016\/j.biortech.2026.134588_b0180","doi-asserted-by":"crossref","first-page":"59","DOI":"10.3390\/ph9030059","article-title":"Antimicrobial peptides targeting gram-positive bacteria","volume":"9","author":"Malanovic","year":"2016","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.biortech.2026.134588_b0185","doi-asserted-by":"crossref","first-page":"2147","DOI":"10.1080\/10408398.2017.1308312","article-title":"Plant proteases for bioactive peptides release: a review","volume":"58","author":"Mazorra-Manzano","year":"2018","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.biortech.2026.134588_b0190","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1016\/j.bbamem.2015.12.013","article-title":"Improving short antimicrobial peptides despite elusive rules for activity","volume":"1858","author":"Mikut","year":"2016","journal-title":"Biochim. Biophys. Acta - Biomembr."},{"key":"10.1016\/j.biortech.2026.134588_b0195","doi-asserted-by":"crossref","DOI":"10.1155\/2023\/1792917","article-title":"Evaluation of antimicrobial and antioxidant activities of casein\u2010derived bioactive peptides using trypsin enzyme","volume":"2023","author":"Mokhtari","year":"2023","journal-title":"J. Food Qual."},{"key":"10.1016\/j.biortech.2026.134588_b0200","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2021.668632","article-title":"Antimicrobial peptides: a new hope in biomedical and pharmaceutical fields","volume":"11","author":"Moretta","year":"2021","journal-title":"Front. Cell. Infect. Microbiol."},{"key":"10.1016\/j.biortech.2026.134588_b0205","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1016\/j.peptides.2008.01.011","article-title":"Bovine hemoglobin: an attractive source of antibacterial peptides","volume":"29","author":"Nedjar-Arroume","year":"2008","journal-title":"Peptides"},{"key":"10.1016\/j.biortech.2026.134588_b0210","doi-asserted-by":"crossref","first-page":"2082","DOI":"10.1016\/j.peptides.2006.03.033","article-title":"Isolation and characterization of four antibacterial peptides from bovine hemoglobin","volume":"27","author":"Nedjar-Arroume","year":"2006","journal-title":"Peptides"},{"key":"10.1016\/j.biortech.2026.134588_b0215","doi-asserted-by":"crossref","DOI":"10.1016\/j.lwt.2021.112357","article-title":"Water-holding capacity of enzymatic protein hydrolysates: a study on the synergistic effects of peptide fractions","volume":"152","author":"Nu\u00f1ez","year":"2021","journal-title":"LWT"},{"key":"10.1016\/j.biortech.2026.134588_b0220","first-page":"525","article-title":"Environmental impact of abattoir waste discharge on the quality of surface water and ground water in Abeokuta","volume":"7","author":"Ojekunle","year":"2017","journal-title":"J. Env. Anal. Toxicol."},{"key":"10.1016\/j.biortech.2026.134588_b0225","unstructured":"Orzechowski, K., 2024. Global Animal Slaughter Statistics & Charts."},{"key":"10.1016\/j.biortech.2026.134588_b0230","doi-asserted-by":"crossref","first-page":"11921","DOI":"10.3390\/ijms241511921","article-title":"Potential of human hemoglobin as a source of bioactive peptides: comparative study of enzymatic hydrolysis with bovine hemoglobin and the production of active peptide \u03b1137\u2013141","volume":"24","author":"Outman","year":"2023","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.biortech.2026.134588_b0235","doi-asserted-by":"crossref","first-page":"2219","DOI":"10.1016\/j.biortech.2010.09.121","article-title":"Anaerobic digestion of slaughterhouse waste: main process limitations and microbial community interactions","volume":"102","author":"Palatsi","year":"2011","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2026.134588_b0240","article-title":"Isolation of two novel anti-glycation peptides from highland barley (Hordeum vulgare L.) protein hydrolysates: structural characteristics and mechanism of action against advanced glycation end-products (AGEs)","volume":"107195","author":"Phyo","year":"2025","journal-title":"Food Biosci."},{"key":"10.1016\/j.biortech.2026.134588_b0245","article-title":"Impact of hydrolysis duration and discoloration on peptide profiles and antimicrobial properties in chicken cruor hydrolysates: identification of five novel antifungal peptides","volume":"148763","author":"Rahimi","year":"2026","journal-title":"Food Chem."},{"key":"10.1016\/j.biortech.2026.134588_b0250","doi-asserted-by":"crossref","first-page":"268","DOI":"10.4103\/RPS.RPS_70_23","article-title":"Designing of a novel chimeric antimicrobial peptide against Acinetobacter baumannii using three different bioinformatics methods and evaluation of its antimicrobial activity in vitro","volume":"20","author":"Rakhshani","year":"2025","journal-title":"Res. Pharm. Sci."},{"key":"10.1016\/j.biortech.2026.134588_b0255","doi-asserted-by":"crossref","first-page":"522","DOI":"10.1080\/21505594.2017.1313372","article-title":"Strategies for combating bacterial biofilms: a focus on anti-biofilm agents and their mechanisms of action","volume":"9","author":"Roy","year":"2018","journal-title":"Virulence"},{"key":"10.1016\/j.biortech.2026.134588_b0260","doi-asserted-by":"crossref","first-page":"1687","DOI":"10.1021\/acsfoodscitech.1c00141","article-title":"Effect of pH on the antimicrobial activity and peptide population of pepsin hydrolysates derived from bovine and porcine hemoglobins","volume":"1","author":"Sanchez-Reinoso","year":"2021","journal-title":"ACS Food Sci. Technol."},{"key":"10.1016\/j.biortech.2026.134588_b0265","doi-asserted-by":"crossref","first-page":"36","DOI":"10.3390\/fermentation11010036","article-title":"Antimicrobial peptides, their production, and potential in the fight against antibiotic-resistant pathogens","volume":"11","author":"Saubenova","year":"2025","journal-title":"Fermentation"},{"key":"10.1016\/j.biortech.2026.134588_b0270","article-title":"A simple tandem bioassay-guided SCX-RP SPE fractionation for efficient active peptide screening from Inca nut cake protein hydrolysate","volume":"124061","author":"Sutopo","year":"2024","journal-title":"J. Chromatogr. B"},{"key":"10.1016\/j.biortech.2026.134588_b0275","first-page":"8","article-title":"Estimation of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of antimicrobial peptides of Saccharomyces boulardii against selected pathogenic strains","volume":"5","author":"Srirama","year":"2019","journal-title":"Karbala Int. J. Mod. Sci."},{"key":"10.1016\/j.biortech.2026.134588_b0280","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s11274-020-02964-6","article-title":"A rapid and simple measurement method for biofilm formation inhibitory activity using 96-pin microtiter plate lids","volume":"36","author":"Tsukatani","year":"2020","journal-title":"World J. Microbiol. Biotechnol."},{"key":"10.1016\/j.biortech.2026.134588_b0285","doi-asserted-by":"crossref","DOI":"10.1016\/j.compbiolchem.2024.108276","article-title":"Screening and computational characterization of novel antimicrobial cathelicidins from amphibian transcriptomic data","volume":"113","author":"Varela-Rodr\u00edguez","year":"2024","journal-title":"Comput. Biol. Chem."},{"key":"10.1016\/j.biortech.2026.134588_b0290","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1007\/s40003-018-0350-6","article-title":"Antioxidant and antimicrobial efficacy of peptidic hydrolysate obtained from porcine blood","volume":"8","author":"Verma","year":"2019","journal-title":"Agric. Res."},{"key":"10.1016\/j.biortech.2026.134588_b0295","doi-asserted-by":"crossref","first-page":"2084","DOI":"10.1071\/AN16804","article-title":"Efficacy of antioxidant and antimicrobial activity of whole porcine blood hydrolysates and its fractions under in-vitro conditions","volume":"58","author":"Verma","year":"2018","journal-title":"Anim. Prod. Sci."},{"key":"10.1016\/j.biortech.2026.134588_b0300","doi-asserted-by":"crossref","DOI":"10.1016\/j.lwt.2024.116499","article-title":"Novel antioxidant peptides from bovine blood: purification, identification and mechanism of action","volume":"205","author":"Wang","year":"2024","journal-title":"LWT"},{"key":"10.1016\/j.biortech.2026.134588_b0305","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.158962","article-title":"Advances in the discovery, mechanism of action, optimization of activity and potential for clinical application of antimicrobial peptides","volume":"504","author":"Wang","year":"2025","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.biortech.2026.134588_b0310","doi-asserted-by":"crossref","first-page":"2588","DOI":"10.3390\/molecules26092588","article-title":"Purification and identification of novel antioxidant peptides from enzymatically hydrolysed Samia ricini pupae","volume":"26","author":"Wongsrangsap","year":"2021","journal-title":"Molecules"},{"key":"10.1016\/j.biortech.2026.134588_b0315","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2021.747760","article-title":"Boosting synergistic effects of short antimicrobial peptides with conventional antibiotics against resistant bacteria","volume":"12","author":"Wu","year":"2021","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.biortech.2026.134588_b0320","article-title":"Targeted therapeutic strategies in the battle against pathogenic bacteria","volume":"12","author":"Yang","year":"2021","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.biortech.2026.134588_b0325","doi-asserted-by":"crossref","DOI":"10.1016\/j.biotechadv.2025.108570","article-title":"Advances in antimicrobial peptides: from mechanistic insights to chemical modifications","volume":"81","author":"Yang","year":"2025","journal-title":"Biotechnol. Adv."},{"key":"10.1016\/j.biortech.2026.134588_b0330","doi-asserted-by":"crossref","first-page":"2468","DOI":"10.3390\/ma11122468","article-title":"Action of antimicrobial peptides against bacterial biofilms","volume":"11","author":"Yasir","year":"2018","journal-title":"Materials (Basel)"},{"key":"10.1016\/j.biortech.2026.134588_b0335","doi-asserted-by":"crossref","DOI":"10.1016\/j.lwt.2023.115595","article-title":"A novel endogenous antimicrobial peptide MP-4 derived from koumiss of Inner Mongolia by peptidomics, and effects on Staphylococcus aureus","volume":"191","author":"Zhang","year":"2024","journal-title":"Lwt"},{"key":"10.1016\/j.biortech.2026.134588_b0340","first-page":"1","article-title":"Antimicrobial peptides: mechanism of action, activity and clinical potential","volume":"8","author":"Zhang","year":"2021","journal-title":"Mil. Med. Res."},{"key":"10.1016\/j.biortech.2026.134588_b0345","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2021.113433","article-title":"An optimized analog of antimicrobial peptide Jelleine-1 shows enhanced antimicrobial activity against multidrug resistant P.aeruginosa and negligible toxicity invitro and invivo","volume":"219","author":"Zhou","year":"2021","journal-title":"Eur. J. Med. Chem."}],"container-title":["Bioresource Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960852426006693?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960852426006693?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T06:18:19Z","timestamp":1776925099000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960852426006693"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":69,"alternative-id":["S0960852426006693"],"URL":"https:\/\/doi.org\/10.1016\/j.biortech.2026.134588","relation":{},"ISSN":["0960-8524"],"issn-type":[{"value":"0960-8524","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Circular bioprocessing of bovine blood for peptide-based antimicrobial and antibiofilm agents","name":"articletitle","label":"Article Title"},{"value":"Bioresource Technology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biortech.2026.134588","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"134588"}}