{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T00:35:13Z","timestamp":1793666113032,"version":"4.5.1"},"reference-count":46,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T00:00:00Z","timestamp":1782432000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003130","name":"Research Foundation Flanders","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003130","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioresource Technology"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.biortech.2026.135255","type":"journal-article","created":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T23:37:59Z","timestamp":1782517079000},"page":"135255","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["CO2 availability as process tool to enhance isobutyric acid production in methanol fermentation by Clostridium luticellarii"],"prefix":"10.1016","volume":"459","author":[{"given":"Camille","family":"Petrognani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quinten","family":"Mari\u00ebn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lander De","family":"Vos","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Merlijn van","family":"Oijen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7734-3103","authenticated-orcid":false,"given":"Nico","family":"Boon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramon","family":"Ganigu\u00e9","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biortech.2026.135255_b0005","doi-asserted-by":"crossref","first-page":"42539","DOI":"10.1007\/s11356-022-19718-6","article-title":"A review of the global climate change impacts, adaptation, and sustainable mitigation measures","volume":"29","author":"Abbass","year":"2022","journal-title":"Environ. Sci. Pollut. Res. Int."},{"key":"10.1016\/j.biortech.2026.135255_b0010","unstructured":"Acetic Acid Market Size, Growth, Share & Trends Report 2031 [WWW Document], 2026. Mordor Intell. URL https:\/\/www.mordorintelligence.com\/industry-reports\/acetic-acid-market (accessed 2.6.26)."},{"key":"10.1016\/j.biortech.2026.135255_b0015","doi-asserted-by":"crossref","first-page":"7135","DOI":"10.1021\/es500483w","article-title":"Electrolytic membrane extraction enables fine chemical production from biorefinery sidestreams","volume":"48","author":"Andersen","year":"2014","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.biortech.2026.135255_b0020","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1002\/ceat.200800063","article-title":"Succinic Acid: a New Platform Chemical for Biobased Polymers from Renewable Resources","volume":"31","author":"Bechthold","year":"2008","journal-title":"Chem. Eng. Technol."},{"key":"10.1016\/j.biortech.2026.135255_b0025","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/bs.aambs.2018.01.002","article-title":"Bacterial Anaerobic Synthesis Gas (Syngas) and CO2+ H2Fermentation","author":"Bengelsdorf","year":"2018","journal-title":"Advances in Applied Microbiology."},{"key":"10.1016\/j.biortech.2026.135255_b0030","doi-asserted-by":"crossref","first-page":"1639","DOI":"10.1080\/09593330.2013.827747","article-title":"Bacterial synthesis gas (syngas) fermentation","volume":"34","author":"Bengelsdorf","year":"2013","journal-title":"Environ. Technol."},{"key":"10.1016\/j.biortech.2026.135255_b0035","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2021.725578","article-title":"A Downstream Processing Cascade for Separation of Caproic and Caprylic Acid from Maize Silage-based Fermentation Broth","volume":"9","author":"Braune","year":"2021","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.biortech.2026.135255_b0040","doi-asserted-by":"crossref","first-page":"9724","DOI":"10.1038\/s41598-018-27594-9","article-title":"A novel high-throughput method for kinetic characterisation of anaerobic bioproduction strains, applied to Clostridium kluyveri","volume":"8","author":"Candry","year":"2018","journal-title":"Sci. Rep."},{"key":"10.1016\/j.biortech.2026.135255_b0045","article-title":"Isobutyrate biosynthesis via methanol chain elongation: Converting organic wastes to platform chemicals","author":"Chen","year":"2016","journal-title":"J. Chem. Technol. Biotechnol."},{"key":"10.1016\/j.biortech.2026.135255_b0050","doi-asserted-by":"crossref","first-page":"981","DOI":"10.1002\/bit.27253","article-title":"Real\u2010time dissolved carbon dioxide monitoring I: Application of a novel in situ sensor for CO2 monitoring and control","volume":"117","author":"Chopda","year":"2020","journal-title":"Biotechnol. Bioeng."},{"key":"10.1016\/j.biortech.2026.135255_b0055","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1016\/j.copbio.2019.10.002","article-title":"Renewable methanol and formate as microbial feedstocks","volume":"62","author":"Cotton","year":"2020","journal-title":"Curr. Opin. Biotechnol., Energy Biotechnologyy \u25cf Environmental Biotechnology"},{"key":"10.1016\/j.biortech.2026.135255_b0060","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.jcou.2014.12.001","article-title":"Carbon capture, storage and utilisation technologies: a critical analysis and comparison of their life cycle environmental impacts","volume":"9","author":"Cu\u00e9llar-Franca","year":"2015","journal-title":"J. CO2 Util."},{"key":"10.1016\/j.biortech.2026.135255_b0065","doi-asserted-by":"crossref","first-page":"8184","DOI":"10.1021\/acssuschemeng.0c00907","article-title":"Methanol-based Chain Elongation with Acetate to n-Butyrate and Isobutyrate at Varying Selectivities Dependent on pH","volume":"8","author":"De Leeuw","year":"2020","journal-title":"ACS Sustain. Chem. Eng."},{"key":"10.1016\/j.biortech.2026.135255_b0070","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1196\/annals.1419.016","article-title":"Old Acetogens , New Light Old Acetogens, New Ligh","volume":"1125","author":"Drake","year":"2008","journal-title":"Ann. n. y. Acad. Sci."},{"key":"10.1016\/j.biortech.2026.135255_b0075","unstructured":"First Large-Scale E-Methanol Facility Ready to Deliver to Maersk [WWW Document], n.d. Marit. Exec. URL https:\/\/maritime-executive.com\/article\/first-large-scale-e-methanol-facility-ready-to-deliver-to-maersk-and-other (accessed 2.6.26)."},{"key":"10.1016\/j.biortech.2026.135255_b0080","doi-asserted-by":"crossref","first-page":"1923","DOI":"10.1039\/D0EE00787K","article-title":"Minimizing CO2 emissions with renewable energy: a comparative study of emerging technologies in the steel industry","volume":"13","author":"Flores-Granobles","year":"2020","journal-title":"Energy Environ. Sci."},{"key":"10.1016\/j.biortech.2026.135255_b0085","author":"Gois","year":"2025","journal-title":"Distinct Acetate Utilization Strategies Differentiate Butyrate and Octanoate Producing Chain-Elongating Bacteria."},{"key":"10.1016\/j.biortech.2026.135255_b0090","series-title":"CRC Handbook of Chemistry and Physics","author":"Haynes","year":"2014"},{"key":"10.1016\/j.biortech.2026.135255_b0095","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1038\/s41586-019-1681-6","article-title":"The technological and economic prospects for CO2 utilization and removal","volume":"575","author":"Hepburn","year":"2019","journal-title":"Nature"},{"key":"10.1016\/j.biortech.2026.135255_b0100","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1385\/ABAB:79:1-3:609","article-title":"Biomass conversion to mixed alcohol fuels using the MixAlco process","volume":"77\u201379","author":"Holtzapple","year":"1999","journal-title":"Appl. Biochem. Biotechnol."},{"key":"10.1016\/j.biortech.2026.135255_b0105","unstructured":"Howard, G., Hujsack, K.L., Jean, E.N., Hagan, J.J., Hainbach, J.J., 1965. Azeotropic distillation process. US3214347A."},{"key":"10.1016\/j.biortech.2026.135255_b0110","doi-asserted-by":"crossref","first-page":"5119","DOI":"10.1007\/s00253-020-10551-w","article-title":"Open microbiome dominated by Clostridium and Eubacterium converts methanol into i-butyrate and n-butyrate","volume":"104","author":"Huang","year":"2020","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.biortech.2026.135255_b0115","unstructured":"Intergovernmental Panel on Climate Change (IPCC), 2018. Global warming of 1.5\u202f\u00b0C: An IPCC special report on the impacts of global warming of 1.5\u202f\u00b0C above pre-industrial levels and related global greenhouse gas emission pathways, in the context of strengthening the global response to climate change, sustainable development, and efforts to eradicate poverty (V. Masson-Delmotte et al., Eds.)."},{"key":"10.1016\/j.biortech.2026.135255_b0120","doi-asserted-by":"crossref","DOI":"10.1093\/femsre\/fuaa040","article-title":"Methanol and methyl group conversion in acetogenic bacteria: biochemistry, physiology and application","volume":"45","author":"Kremp","year":"2021","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.biortech.2026.135255_b0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.micromeso.2022.111768","article-title":"Zeolite adsorbents for the separation of n-butyric acid from fermentation broths via adsorption","volume":"334","author":"Lee","year":"2022","journal-title":"Microporous Mesoporous Mater."},{"key":"10.1016\/j.biortech.2026.135255_b0130","doi-asserted-by":"crossref","first-page":"3124","DOI":"10.1111\/1462-2920.16011","article-title":"One substrate, many fates: different ways of methanol utilization in the acetogen Acetobacterium woodii","volume":"24","author":"Litty","year":"2022","journal-title":"Environ. Microbiol."},{"key":"10.1016\/j.biortech.2026.135255_b0135","unstructured":"Lungu, E., 2025. Biomethanol-methanol diff widens, UK demand ticks up | Latest Market News [WWW Document]. URL https:\/\/www.argusmedia.com\/en\/news-and-insights\/latest-market-news\/2658115-biomethanol-methanol-diff-widens-uk-demand-ticks-up (accessed 6.16.26)."},{"key":"10.1016\/j.biortech.2026.135255_b0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.153216","article-title":"Isobutyric and n-butyric acid production from H2 and CO2 by Clostridium luticellarii in a hollow fiber membrane biofilm reactor: reactor operation and process modelling","volume":"495","author":"Mari\u00ebn","year":"2024","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.biortech.2026.135255_b0145","doi-asserted-by":"crossref","DOI":"10.1111\/1751-7915.14321","article-title":"Steerable isobutyric and butyric acid production from CO2 and H2 by Clostridium luticellarii","volume":"17","author":"Mari\u00ebn","year":"2024","journal-title":"Microb. Biotechnol."},{"key":"10.1016\/j.biortech.2026.135255_b0150","doi-asserted-by":"crossref","DOI":"10.1088\/2516-1083\/abf1ce","article-title":"A review of direct air capture (DAC): scaling up commercial technologies and innovating for the future","volume":"3","author":"McQueen","year":"2021","journal-title":"Prog. Energy"},{"key":"10.1016\/j.biortech.2026.135255_b0155","unstructured":"Methanol Market Size, Share, Trends Analysis & Industry Report, 2031 [WWW Document], 2026. Mordor Intell. URL https:\/\/www.mordorintelligence.com\/industry-reports\/methanol-market (accessed 2.6.26)."},{"key":"10.1016\/j.biortech.2026.135255_b0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2016.03.094","article-title":"Carbon recovery by fermentation of CO-rich off gases \u2013 turning steel mills into biorefineries","author":"Molitor","year":"2016","journal-title":"Bioresour. Technol. in Press."},{"key":"10.1016\/j.biortech.2026.135255_b0165","doi-asserted-by":"crossref","first-page":"5013","DOI":"10.1016\/j.biortech.2009.12.098","article-title":"Biomass-derived syngas fermentation into biofuels: Opportunities and challenges","volume":"101","author":"Munasinghe","year":"2010","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2026.135255_b0170","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1186\/s13068-022-02146-6","article-title":"Energy-efficient recovery of fermented butyric acid using octyl acetate extraction","volume":"15","author":"Oh","year":"2022","journal-title":"Biotechnol. Biofuels Bioprod."},{"key":"10.1016\/j.biortech.2026.135255_b0175","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1007\/BF01567972","article-title":"Methanol metabolism byEubacterium limosum B2: Effects of pH and carbon dioxide on growth and organic acid production","volume":"12","author":"Pacaud","year":"1985","journal-title":"Curr. Microbiol."},{"key":"10.1016\/j.biortech.2026.135255_b0180","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1007\/BF00257028","article-title":"Organic acid production during methylotrophic growth of Eubacterium limosum B2: displacement towards increased butyric acid yields by supplementing with acetate","volume":"23","author":"Pacaud","year":"1986","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.biortech.2026.135255_b0185","doi-asserted-by":"crossref","first-page":"8389","DOI":"10.1039\/D0GC02700F","article-title":"Production of isobutyric acid from methanol by Clostridium luticellarii","volume":"22","author":"Petrognani","year":"2020","journal-title":"Green Chem."},{"key":"10.1016\/j.biortech.2026.135255_b0190","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1002\/bbb.1773","article-title":"Methanol as carbon substrate in the bio-economy: Metabolic engineering of aerobic methylotrophic bacteria for production of value-added chemicals","volume":"11","author":"Pfeifenschneider","year":"2017","journal-title":"Biofuels Bioprod. Biorefining"},{"key":"10.1016\/j.biortech.2026.135255_b0195","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/0032-9592(94)80054-5","article-title":"On-line automated monitoring and control systems for CO2 and O2 in aerobic and anaerobic solid-state fermentations","volume":"29","author":"Saucedo-Casta\u00f1eda","year":"1994","journal-title":"Process Biochem."},{"key":"10.1016\/j.biortech.2026.135255_b0200","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1038\/nrmicro3365","article-title":"Autotrophy at the thermodynamic limit of life: a model for energy conservation in acetogenic bacteria","volume":"12","author":"Schuchmann","year":"2014","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.biortech.2026.135255_b0205","unstructured":"Spekreijse, J., Lammens, T., Parisi, C., Ronzon, T., Vis, M., 2019. Insights into the European market for bio-based chemicals [WWW Document]. JRC Publ. Repos. https:\/\/doi.org\/10.2760\/18942."},{"key":"10.1016\/j.biortech.2026.135255_b0210","doi-asserted-by":"crossref","first-page":"606","DOI":"10.1111\/1751-7915.13270","article-title":"Using gas mixtures of CO, CO2 and H2 as microbial substrates: the do\u2019s and don\u2019ts of successful technology transfer from laboratory to production scale","volume":"11","author":"Takors","year":"2018","journal-title":"Microb. Biotechnol."},{"key":"10.1016\/j.biortech.2026.135255_b0215","unstructured":"The Shunli CO2-to-Methanol Production Plant [WWW Document], n.d. CRI - Carbon Recycl. Int. URL https:\/\/carbonrecycling.com\/projects\/shunli (accessed 2.6.26)."},{"key":"10.1016\/j.biortech.2026.135255_b0220","doi-asserted-by":"crossref","first-page":"605","DOI":"10.1007\/s00253-021-11742-9","article-title":"Production of a newly discovered PHA family member with an isobutyrate-fed enrichment culture","volume":"106","author":"Vermeer","year":"2022","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.biortech.2026.135255_b0225","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcou.2023.102477","article-title":"A comprehensive review of electrochemical reduction of CO2 to methanol: Technical and design aspects","volume":"71","author":"Wiranarongkorn","year":"2023","journal-title":"J. CO2 Util."},{"key":"10.1016\/j.biortech.2026.135255_b0230","doi-asserted-by":"crossref","DOI":"10.1126\/science.adn9388","article-title":"Hydrogenation of CO2 for sustainable fuel and chemical production","volume":"387","author":"Ye","year":"2025","journal-title":"Science"}],"container-title":["Bioresource Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960852426013374?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960852426013374?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,19]],"date-time":"2026-08-19T06:59:13Z","timestamp":1787122753000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960852426013374"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":46,"alternative-id":["S0960852426013374"],"URL":"https:\/\/doi.org\/10.1016\/j.biortech.2026.135255","relation":{},"ISSN":["0960-8524"],"issn-type":[{"value":"0960-8524","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CO2 availability as process tool to enhance isobutyric acid production in methanol fermentation by Clostridium luticellarii","name":"articletitle","label":"Article Title"},{"value":"Bioresource Technology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biortech.2026.135255","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}],"article-number":"135255"}}