{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T01:39:28Z","timestamp":1792373968956,"version":"4.4.0"},"reference-count":79,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,11,1]],"date-time":"2026-11-01T00:00:00Z","timestamp":1793491200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Bioresource Technology"],"published-print":{"date-parts":[[2026,11]]},"DOI":"10.1016\/j.biortech.2026.135363","type":"journal-article","created":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T15:41:48Z","timestamp":1783698108000},"page":"135363","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["A study on the combined toxicity assessment of sulfamethoxazole and tetracycline hydrochloride in actual aquaculture wastewater using Chlorella vulgaris and the mechanisms of their removal"],"prefix":"10.1016","volume":"460","author":[{"given":"Yujie","family":"Jiao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingyuan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guotao","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangjie","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanhui","family":"Ha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiawei","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sujin","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaqi","family":"Mao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biortech.2026.135363_b0005","doi-asserted-by":"crossref","DOI":"10.1016\/j.jece.2024.115068","article-title":"Advancements and challenges in Fenton-based advanced oxidation processes for antibiotic removal in wastewater: from the laboratory to practical applications","volume":"13","author":"Ahmed","year":"2025","journal-title":"J. Environ. Chem. Eng."},{"key":"10.1016\/j.biortech.2026.135363_b0010","doi-asserted-by":"crossref","first-page":"32475","DOI":"10.1007\/s11356-021-12950-6","article-title":"Effects of zinc and mercury on ROS-mediated oxidative stress-induced physiological impairments and antioxidant responses in the microalga Chlorella vulgaris","volume":"28","author":"Ajitha","year":"2021","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.biortech.2026.135363_b0015","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1016\/j.cej.2018.07.036","article-title":"Detoxification and degradation of sulfamethoxazole by soybean peroxidase and UV+H2O2 remediation approaches","volume":"352","author":"Al-Maqdi","year":"2018","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.biortech.2026.135363_b0020","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1080\/19443994.2013.826325","article-title":"Nutrient removal of nursery and municipal wastewater using Chlorella vulgaris microalgae for lipid extraction","volume":"52","author":"Aravinthan","year":"2014","journal-title":"Desalin. Water Treat."},{"key":"10.1016\/j.biortech.2026.135363_b0025","first-page":"1","article-title":"Antioxidant response mechanism of freshwater microalgae species to reactive oxygen species production: a mini review","volume":"36","author":"Ay","year":"2019","journal-title":"Chem. Ecol."},{"key":"10.1016\/j.biortech.2026.135363_b0030","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23158130","article-title":"Photocatalytic degradation of some typical antibiotics: recent advances and future outlooks","volume":"23","author":"Bai","year":"2022","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.biortech.2026.135363_b0035","doi-asserted-by":"crossref","DOI":"10.1155\/2016\/5656304","article-title":"The effect of kanamycin and tetracycline on growth and photosynthetic activity of two chlorophyte algae","volume":"2016","author":"Bashir","year":"2016","journal-title":"Biomed Res. Int."},{"key":"10.1016\/j.biortech.2026.135363_b0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.algal.2026.104574","article-title":"Trophic mode-dependent antibiotic sensitivity in the green microalgae Chlorella vulgaris and Chlamydomonas reinhardtii","volume":"94","author":"Chen","year":"2026","journal-title":"Algal Res."},{"key":"10.1016\/j.biortech.2026.135363_b0045","article-title":"Carbon dots alleviate photoinhibition and enhance photosynthesis in Chlorella pyrenoidosa","volume":"507","author":"Chen","year":"2025","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.biortech.2026.135363_b0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.122570","article-title":"Influence of roxithromycin as antibiotic residue on volatile fatty acids recovery in anaerobic fermentation of waste activated sludge","volume":"394","author":"Chen","year":"2020","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.biortech.2026.135363_b0055","article-title":"Chlorella vulgaris mediated erythromycin co-metabolism: stress response, degradation products and pathways","volume":"13","author":"Chen","year":"2025","journal-title":"J. Environ. Chem. Eng."},{"key":"10.1016\/j.biortech.2026.135363_b0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.algal.2025.104294","article-title":"The stress response and removal mechanism of Chlorella vulgaris to sulfamethoxazole","volume":"91","author":"Chen","year":"2025","journal-title":"Algal Res."},{"key":"10.1016\/j.biortech.2026.135363_b0065","article-title":"Relationship between photosynthetic fluorescence parameters of algae and the initial biomass in the measurement of water quality biological toxicity","volume":"51","author":"Chen","year":"2022","journal-title":"gzxb"},{"key":"10.1016\/j.biortech.2026.135363_b0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.114554","article-title":"Ecotoxicological effects of sulfonamides and fluoroquinolones and their removal by a green alga (Chlorella vulgaris) and a cyanobacterium (Chrysosporum ovalisporum)","volume":"263","author":"Chen","year":"2020","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.biortech.2026.135363_b0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2023.129409","article-title":"New insight into the concentration-dependent removal of multiple antibiotics by Chlorella sorokiniana","volume":"385","author":"Chu","year":"2023","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2026.135363_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2022.118834","article-title":"Biotransformation of sulfamethoxazole by microalgae: removal efficiency, pathways, and mechanisms","volume":"221","author":"Chu","year":"2022","journal-title":"Water Res."},{"key":"10.1016\/j.biortech.2026.135363_b0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2020.140872","article-title":"Single and simultaneous adsorption of three sulfonamides in agricultural soils: effects of pH and organic matter content","volume":"744","author":"Conde-Cid","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.biortech.2026.135363_b0090","doi-asserted-by":"crossref","first-page":"446","DOI":"10.1016\/j.jhazmat.2012.05.106","article-title":"Tetracycline removal during wastewater treatment in high-rate algal ponds","volume":"229\u2013230","author":"de Godos","year":"2012","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.biortech.2026.135363_b0095","article-title":"Tetracycline speciation study in aqueous medium: abstract","author":"Diego","year":"2025","journal-title":"Citation (BibTeX) & Reference | Bohrium."},{"key":"10.1016\/j.biortech.2026.135363_b0100","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1007\/s00128-020-02952-4","article-title":"Effects of sulfamethoxazole exposure on the growth, antioxidant system of Chlorella vulgaris and Microcystis aeruginosa","volume":"105","author":"Dong","year":"2020","journal-title":"Bull. Environ. Contam. Toxicol."},{"key":"10.1016\/j.biortech.2026.135363_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.radphyschem.2025.112939","article-title":"Degradation of tetracycline in aqueous solution by electron beam: kinetics and degradation mechanism","volume":"236","author":"Dong","year":"2025","journal-title":"Radiat. Phys. Chem."},{"key":"10.1016\/j.biortech.2026.135363_b0110","doi-asserted-by":"crossref","first-page":"8264","DOI":"10.3390\/ijerph19148264","article-title":"Seasonal pollution characteristics of antibiotics on pig farms of different scales","volume":"19","author":"Du","year":"2022","journal-title":"Int. J. Environ. Res. Public Health"},{"key":"10.1016\/j.biortech.2026.135363_b0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.ecoenv.2020.110609","article-title":"Effects of Bisphenol a on the microalga Chlamydomonas reinhardtii and the clam Corbicula fluminea","volume":"197","author":"Esperanza","year":"2020","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.biortech.2026.135363_b0120","doi-asserted-by":"crossref","first-page":"14178","DOI":"10.1007\/s11356-024-32026-5","article-title":"Removal efficiencies of seven frequently detected antibiotics and related physiological responses in three microalgae species","volume":"31","author":"Frascaroli","year":"2024","journal-title":"Environ. Sci. Pollut. Res."},{"key":"10.1016\/j.biortech.2026.135363_b0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2021.125069","article-title":"A review targeting veterinary antibiotics removal from livestock manure management systems and future outlook","volume":"333","author":"Gaballah","year":"2021","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2026.135363_b0130","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.ecoenv.2016.03.032","article-title":"Single and mixture toxicity of pharmaceuticals and chlorophenols to freshwater algae Chlorella vulgaris","volume":"129","author":"Geiger","year":"2016","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.biortech.2026.135363_b0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.seppur.2022.121454","article-title":"Black phosphorus quantum dots and Ag nanoparticles co-modified TiO2 nanorod arrays as powerful photocatalyst for tetracycline hydrochloride degradation: pathways, toxicity assessment, and mechanism insight","volume":"297","author":"Guo","year":"2022","journal-title":"Sep. Purif. Technol."},{"key":"10.1016\/j.biortech.2026.135363_b0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2019.105376","article-title":"Comparison of oxidative stress induced by clarithromycin in two freshwater microalgae Raphidocelis subcapitata and Chlorella vulgaris","volume":"219","author":"Guo","year":"2020","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.biortech.2026.135363_b0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.124041","article-title":"Removal of pharmaceutical and personal care products (PPCPs) from wastewater using microalgae: a review","volume":"403","author":"Hena","year":"2021","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.biortech.2026.135363_b0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.algal.2021.102399","article-title":"Simultaneously measuring carbon uptake capacity and chlorophyll a fluorescence dynamics in algae","volume":"58","author":"Hupp","year":"2021","journal-title":"Algal Res."},{"key":"10.1016\/j.biortech.2026.135363_b0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.rechem.2025.102047","article-title":"Alkali metal salt modulated visible photocatalytic degradation of tetracycline hydrochloride by g-C3N4: degradation pathway, mechanism and toxicity assessment","volume":"13","author":"Jiao","year":"2025","journal-title":"Results Chem."},{"key":"10.1016\/j.biortech.2026.135363_b0160","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2025.123493","article-title":"Structural optimization and photocatalytic performance of kaolin\/CaCN composite materials: toward remediation and risk mitigation of tetracycline pollution in aquaculture effluent","volume":"290","author":"Jiao","year":"2026","journal-title":"Environ. Res."},{"key":"10.1016\/j.biortech.2026.135363_b0165","doi-asserted-by":"crossref","first-page":"1596","DOI":"10.3390\/w17111596","article-title":"Kinetic analysis and transformation pathways of sulfamethoxazole degradation in water and wastewater under electron beam irradiation","volume":"17","author":"Kengne","year":"2025","journal-title":"Water"},{"key":"10.1016\/j.biortech.2026.135363_b0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2019.121985","article-title":"Dissipation of antibiotics by microalgae: kinetics, identification of transformation products and pathways","volume":"387","author":"Kiki","year":"2020","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.biortech.2026.135363_b0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2021.133438","article-title":"Microalgal mediated antibiotic co-metabolism: kinetics, transformation products and pathways","volume":"292","author":"Kiki","year":"2022","journal-title":"Chemosphere"},{"key":"10.1016\/j.biortech.2026.135363_b0180","doi-asserted-by":"crossref","first-page":"720","DOI":"10.3390\/pr8060720","article-title":"Occurrence and removal of veterinary antibiotics in livestock wastewater treatment plants, South Korea","volume":"8","author":"Kim","year":"2020","journal-title":"Processes"},{"key":"10.1016\/j.biortech.2026.135363_b0185","doi-asserted-by":"crossref","first-page":"518","DOI":"10.3390\/nano15070518","article-title":"Comparison of the level and mechanisms of toxicity of nanoparticles of underwater welding in bioassay with three marine microalgae","volume":"15","author":"Kirichenko","year":"2025","journal-title":"Nanomaterials"},{"key":"10.1016\/j.biortech.2026.135363_b0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2020.122149","article-title":"Toxicity of benzophenone-3 and its biodegradation in a freshwater microalga Scenedesmus obliquus","volume":"389","author":"Lee","year":"2020","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.biortech.2026.135363_b0195","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.scitotenv.2015.03.070","article-title":"Occurrence of antibiotics in soils and manures from greenhouse vegetable production bases of Beijing, China and an associated risk assessment","volume":"521\u2013522","author":"Li","year":"2015","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.biortech.2026.135363_b0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.aquatox.2024.106937","article-title":"Effects of sulfamonomethoxine and trimethoprim co-exposures at different environmentally relevant concentrations on microalgal growth and nutrient assimilation","volume":"271","author":"Li","year":"2024","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.biortech.2026.135363_b0205","doi-asserted-by":"crossref","first-page":"1163","DOI":"10.1016\/j.biortech.2016.07.080","article-title":"Effect of tetracycline on the growth and nutrient removal capacity of Chlamydomonas reinhardtii in simulated effluent from wastewater treatment plants","volume":"218","author":"Li","year":"2016","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2026.135363_b0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclepro.2024.144611","article-title":"Effects of sulfamethoxazole on Chlorella vulgaris growth, pollutant removal, and algal physicochemical properties in a suspended-attached microalgae culture system","volume":"486","author":"Li","year":"2025","journal-title":"J. Clean. Prod."},{"key":"10.1016\/j.biortech.2026.135363_b0215","doi-asserted-by":"crossref","DOI":"10.1360\/nso\/20220029","article-title":"Antibiotics in global rivers","volume":"1","author":"Li","year":"2022","journal-title":"NSO"},{"key":"10.1016\/j.biortech.2026.135363_b0220","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1016\/j.scitotenv.2018.01.271","article-title":"Antibiotics in the aquatic environments: a review of lakes, China","volume":"627","author":"Liu","year":"2018","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.biortech.2026.135363_b0225","doi-asserted-by":"crossref","first-page":"442","DOI":"10.3390\/fermentation11080442","article-title":"Monitoring C. vulgaris cultivations grown on winery wastewater using flow cytometry","volume":"11","author":"Lopes da Silva","year":"2025","journal-title":"Fermentation"},{"key":"10.1016\/j.biortech.2026.135363_b0230","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclepro.2024.142364","article-title":"Construction of AgI\/PCN-224 Z-scheme heterojunction for efficient photocatalytic degradation of tetracycline hydrochloride: Pathways, mechanism and theoretical calculations","volume":"456","author":"Lu","year":"2024","journal-title":"J. Clean. Prod."},{"key":"10.1016\/j.biortech.2026.135363_b0235","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2023.165120","article-title":"Stress of cupric ion and oxytetracycline in Chlorella vulgaris cultured in swine wastewater","volume":"895","author":"Luo","year":"2023","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.biortech.2026.135363_b0240","doi-asserted-by":"crossref","DOI":"10.3390\/catal14110762","article-title":"Recent advances in photocatalytic degradation of tetracycline antibiotics","volume":"14","author":"Ma","year":"2024","journal-title":"Catalysts"},{"key":"10.1016\/j.biortech.2026.135363_b0245","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1016\/j.scitotenv.2016.03.053","article-title":"Characterization of pharmaceutically active compounds in Dongting Lake, China: Occurrence, chiral profiling and environmental risk","volume":"557\u2013558","author":"Ma","year":"2016","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.biortech.2026.135363_b0250","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2024.119225","article-title":"Exploring the influence of sulfadiazine-induced stress on antibiotic removal and transformation pathway using microalgae Chlorella sp","volume":"256","author":"Ma","year":"2024","journal-title":"Environ. Res."},{"key":"10.1016\/j.biortech.2026.135363_b0255","doi-asserted-by":"crossref","DOI":"10.1016\/j.gsd.2024.101181","article-title":"Antibiotic-contaminated wastewater treatment and remediation by electrochemical advanced oxidation processes (EAOPs)","volume":"25","author":"Mahmud","year":"2024","journal-title":"Groundw. Sustain. Dev."},{"key":"10.1016\/j.biortech.2026.135363_b0260","doi-asserted-by":"crossref","first-page":"2728","DOI":"10.1007\/s12010-023-04371-7","article-title":"Low-cost greywater treatment using polyculture microalgae\u2014microalgal growth, organics, and nutrient removal subject to ph and temperature variations during the treatment","volume":"196","author":"Mohit","year":"2024","journal-title":"Appl. Biochem. Biotechnol."},{"key":"10.1016\/j.biortech.2026.135363_b0265","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.biortech.2017.02.011","article-title":"Photodegradation and sorption govern tetracycline removal during wastewater treatment in algal ponds","volume":"232","author":"Norvill","year":"2017","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2026.135363_b0270","doi-asserted-by":"crossref","DOI":"10.1016\/j.jwpe.2025.106960","article-title":"A review of the recent advancements in adsorption technology for removing antibiotics from hospital wastewater","volume":"70","author":"Nugraha","year":"2025","journal-title":"J. Water Process Eng."},{"key":"10.1016\/j.biortech.2026.135363_b0275","doi-asserted-by":"crossref","first-page":"7234","DOI":"10.1021\/acs.est.9b01131","article-title":"Insights into the fate and removal of antibiotics in engineered biological treatment systems: a critical review","volume":"53","author":"Oberoi","year":"2019","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.biortech.2026.135363_b0280","doi-asserted-by":"crossref","unstructured":"OECD, 2011. Test No. 201: Freshwater Alga and Cyanobacteria, Growth Inhibition Test. OECD Guidelines for the Testing of Chemicals, Section 2. https:\/\/doi.org\/10.1787\/9789264069923-en.","DOI":"10.1787\/9789264069923-en"},{"key":"10.1016\/j.biortech.2026.135363_b0285","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1016\/j.jhazmat.2018.12.094","article-title":"Kinetic and microbial response of activated sludge community to acute and chronic exposure to tetracycline","volume":"367","author":"Pala-Ozkok","year":"2019","journal-title":"J. Hazard. Mater."},{"key":"10.1016\/j.biortech.2026.135363_b0290","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1007\/s43630-022-00340-x","article-title":"A kinetic study of the photolysis of sulfamethoxazole with special emphasis on the photoisomer","volume":"22","author":"Palm","year":"2023","journal-title":"Photochem. Photobiol. Sci."},{"key":"10.1016\/j.biortech.2026.135363_b0295","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1016\/j.scitotenv.2017.04.214","article-title":"Fate of antibiotics in soil and their uptake by edible crops","volume":"599\u2013600","author":"Pan","year":"2017","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.biortech.2026.135363_b0300","doi-asserted-by":"crossref","first-page":"3510","DOI":"10.1021\/acs.chemrev.8b00299","article-title":"Pharmaceuticals of emerging concern in aquatic systems: chemistry, occurrence, effects, and removal methods","volume":"119","author":"Patel","year":"2019","journal-title":"Chem. Rev."},{"key":"10.1016\/j.biortech.2026.135363_b0305","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1016\/j.envint.2017.10.016","article-title":"Review of antibiotic resistance in China and its environment","volume":"110","author":"Qiao","year":"2018","journal-title":"Environ. Int."},{"key":"10.1016\/j.biortech.2026.135363_b0310","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.jiec.2025.01.025","article-title":"Harnessing nitrogen doped magnetic biochar for efficient antibiotic adsorption and degradation","volume":"148","author":"Rana","year":"2025","journal-title":"J. Ind. Eng. Chem."},{"key":"10.1016\/j.biortech.2026.135363_b0315","doi-asserted-by":"crossref","first-page":"1309","DOI":"10.1016\/j.toxrep.2019.10.001","article-title":"Oxidative damage and antioxidative system in algae","volume":"6","author":"Rezayian","year":"2019","journal-title":"Toxicol. Rep."},{"key":"10.1016\/j.biortech.2026.135363_b0320","article-title":"Photocatalytic degradation of antibiotics in water via TiO2-x: research needs for technological advancements","volume":"16","author":"de Silerio-V\u00e1zquez","year":"2024","journal-title":"J. Hazard. Mater. Adv."},{"key":"10.1016\/j.biortech.2026.135363_b0325","doi-asserted-by":"crossref","first-page":"2497","DOI":"10.3390\/agronomy12102497","article-title":"Toxic effects of tetracycline and its removal by the freshwater microalga chlorella pyrenoidosa","volume":"12","author":"Tang","year":"2022","journal-title":"Agronomy"},{"key":"10.1016\/j.biortech.2026.135363_b0330","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1016\/j.aquatox.2019.05.004","article-title":"Combined effects of erythromycin and enrofloxacin on antioxidant enzymes and photosynthesis-related gene transcription in Chlorella vulgaris","volume":"212","author":"Wang","year":"2019","journal-title":"Aquat. Toxicol."},{"key":"10.1016\/j.biortech.2026.135363_b0335","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2022.127987","article-title":"Mixotrophic cultivation of Chlorella pyrenoidosa under sulfadiazine stress: High-value product recovery and toxicity tolerance evaluation","volume":"363","author":"Wang","year":"2022","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2026.135363_b0340","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2023.121598","article-title":"Elucidating microalgae-mediated metabolism for sulfadiazine removal mechanism and transformation pathways","volume":"327","author":"Wang","year":"2023","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.biortech.2026.135363_b0345","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2019.123933","article-title":"Peroxymonosulfate activation by Co9S8@ S and N co\u2010doped biochar for sulfamethoxazole degradation","volume":"385","author":"Wang","year":"2020","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.biortech.2026.135363_b0350","doi-asserted-by":"crossref","DOI":"10.1016\/j.envint.2023.107812","article-title":"Occurrence and the potential ecological risk of veterinary antimicrobials in swine farm wastewaters in Japan: Seasonal changes, relation to purchased quantity and after termination of oxytetracycline usage","volume":"173","author":"Watanabe","year":"2023","journal-title":"Environ. Int."},{"key":"10.1016\/j.biortech.2026.135363_b0355","doi-asserted-by":"crossref","DOI":"10.1016\/j.envpol.2020.115589","article-title":"Algae-induced photodegradation of antibiotics: a review","volume":"272","author":"Wei","year":"2021","journal-title":"Environ. Pollut."},{"key":"10.1016\/j.biortech.2026.135363_b0360","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.113850","article-title":"Microalgae cultivation for antibiotic oxytetracycline wastewater treatment","volume":"214","author":"Wu","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.biortech.2026.135363_b0365","doi-asserted-by":"crossref","DOI":"10.3389\/fbioe.2020.613768","article-title":"ROS Induce \u03b2-carotene biosynthesis caused by changes of photosynthesis efficiency and energy metabolism in Dunaliella salina under stress conditions","volume":"8","author":"Xi","year":"2021","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.biortech.2026.135363_b0370","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1016\/j.chemosphere.2018.11.146","article-title":"Toxicity of sulfamethazine and sulfamethoxazole and their removal by a green microalga, Scenedesmus obliquus","volume":"218","author":"Xiong","year":"2019","journal-title":"Chemosphere"},{"key":"10.1016\/j.biortech.2026.135363_b0375","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.tibtech.2017.09.003","article-title":"Can microalgae remove pharmaceutical contaminants from water?","volume":"36","author":"Xiong","year":"2018","journal-title":"Trends Biotechnol."},{"key":"10.1016\/j.biortech.2026.135363_b0380","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.ecoenv.2019.02.063","article-title":"Toxic effects of tetracycline and its degradation products on freshwater green algae","volume":"174","author":"Xu","year":"2019","journal-title":"Ecotoxicol. Environ. Saf."},{"key":"10.1016\/j.biortech.2026.135363_b0385","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2025.133493","article-title":"Acetylacetone alleviates tetracycline stress in Chlorella vulgaris: Detoxification mechanisms and adaptive response","volume":"440","author":"Xu","year":"2026","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.biortech.2026.135363_b0390","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2024.173643","article-title":"Seawater Chlorella sp. biofilm for mariculture effluent polishing under environmental combined antibiotics exposure and ecological risk evaluation based on parent antibiotics and transformation products","volume":"939","author":"Yu","year":"2024","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.biortech.2026.135363_b0395","doi-asserted-by":"crossref","DOI":"10.1016\/j.scitotenv.2022.152988","article-title":"Exploring kinetics, removal mechanism and possible transformation products of tigecycline by Chlorella pyrenoidosa","volume":"817","author":"Zhong","year":"2022","journal-title":"Sci. Total Environ."}],"container-title":["Bioresource Technology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960852426014458?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0960852426014458?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,11]],"date-time":"2026-09-11T15:16:39Z","timestamp":1789139799000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0960852426014458"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,11]]},"references-count":79,"alternative-id":["S0960852426014458"],"URL":"https:\/\/doi.org\/10.1016\/j.biortech.2026.135363","relation":{},"ISSN":["0960-8524"],"issn-type":[{"value":"0960-8524","type":"print"}],"subject":[],"published":{"date-parts":[[2026,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A study on the combined toxicity assessment of sulfamethoxazole and tetracycline hydrochloride in actual aquaculture wastewater using Chlorella vulgaris and the mechanisms of their removal","name":"articletitle","label":"Article Title"},{"value":"Bioresource Technology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biortech.2026.135363","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"135363"}}