{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T07:24:04Z","timestamp":1789543444431,"version":"build-2803163510"},"reference-count":30,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,3,1]],"date-time":"2012-03-01T00:00:00Z","timestamp":1330560000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81171415"],"award-info":[{"award-number":["81171415"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Foundation of National Key Discipline in Laboratory Medicine, Chongqing Medical University, China","award":["2010103"],"award-info":[{"award-number":["2010103"]}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2012,3]]},"DOI":"10.1016\/j.bios.2012.01.004","type":"journal-article","created":{"date-parts":[[2012,1,16]],"date-time":"2012-01-16T14:00:40Z","timestamp":1326722440000},"page":"216-221","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":62,"title":["Ultrasensitive electrochemical immunosensor for HE4 based on rolling circle amplification"],"prefix":"10.1016","volume":"33","author":[{"given":"Lingsong","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaohui","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cuixia","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenggui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guoming","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bios.2012.01.004_bib0005","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1007\/s13277-009-0015-y","volume":"31","author":"Anastasi","year":"2010","journal-title":"Tumor Biol."},{"key":"10.1016\/j.bios.2012.01.004_bib0010","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1016\/0302-4598(81)80025-6","volume":"8","author":"Berg","year":"1981","journal-title":"Bioelectrochem. Bioenerg."},{"key":"10.1016\/j.bios.2012.01.004_bib0015","first-page":"2768","volume":"21","author":"Bingle","year":"2002","journal-title":"Ontogeny"},{"key":"10.1016\/j.bios.2012.01.004_bib0020","doi-asserted-by":"crossref","first-page":"383","DOI":"10.1016\/j.bbrc.2005.05.125","volume":"333","author":"Claus","year":"2005","journal-title":"Briochem. Biophys. Res. Commun."},{"key":"10.1016\/j.bios.2012.01.004_bib0025","doi-asserted-by":"crossref","first-page":"3337","DOI":"10.1021\/ac100144g","volume":"82","author":"Cheng","year":"2010","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2012.01.004_bib0030","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1101\/gr.180501","volume":"11","author":"Dean","year":"2001","journal-title":"Genome Res."},{"key":"10.1016\/j.bios.2012.01.004_bib0035","doi-asserted-by":"crossref","first-page":"2162","DOI":"10.1158\/0008-5472.CAN-04-3924","volume":"65","author":"Drapkin","year":"2005","journal-title":"Cancer Res."},{"key":"10.1016\/j.bios.2012.01.004_bib0040","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1007\/BF02980041","volume":"27","author":"Hahn","year":"2004","journal-title":"Arch. Pharm. Res."},{"key":"10.1016\/j.bios.2012.01.004_bib0045","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.canlet.2010.03.013","volume":"296","author":"Hellstrom","year":"2010","journal-title":"Cancer Lett."},{"key":"10.1016\/j.bios.2012.01.004_bib0050","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/978-0-387-68969-2_2","volume":"622","author":"Hellerstrom","year":"2008","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.bios.2012.01.004_bib0055","first-page":"3695","volume":"63","author":"Hellstr\u00f6m","year":"2003","journal-title":"Cancer Res."},{"key":"10.1016\/j.bios.2012.01.004_bib0060","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.aca.2009.11.023","volume":"659","author":"Huang","year":"2010","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.bios.2012.01.004_bib0065","first-page":"71","volume":"58","author":"Jemal","year":"2008","journal-title":"CA Cancer J. Clin."},{"key":"10.1016\/j.bios.2012.01.004_bib0070","doi-asserted-by":"crossref","first-page":"86","DOI":"10.1530\/ror.0.0030086","volume":"3","author":"Kirchhoff","year":"1998","journal-title":"Rev. Reprod."},{"key":"10.1016\/j.bios.2012.01.004_bib0075","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.jcis.2008.01.001","volume":"320","author":"Liang","year":"2008","journal-title":"J. Colloid Interface Sci."},{"key":"10.1016\/j.bios.2012.01.004_bib0080","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1038\/898","volume":"19","author":"Lizardi","year":"1998","journal-title":"Nat. Genet."},{"key":"10.1016\/j.bios.2012.01.004_bib0085","doi-asserted-by":"crossref","first-page":"1256","DOI":"10.1039\/b807913g","volume":"133","author":"Lu","year":"2008","journal-title":"Analyst"},{"key":"10.1016\/j.bios.2012.01.004_bib0090","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1093\/nar\/29.23.e118","volume":"29","author":"Nallur","year":"2001","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bios.2012.01.004_bib0095","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1200\/JCO.2002.20.5.1161","volume":"20","author":"Ozols","year":"2002","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.bios.2012.01.004_bib0100","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1002\/(SICI)1097-0215(19990315)80:6<827::AID-IJC6>3.0.CO;2-P","volume":"80","author":"Parkin","year":"1999","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.bios.2012.01.004_bib0105","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1021\/ja053121d","volume":"128","author":"Radi","year":"2006","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bios.2012.01.004_bib0110","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1016\/j.colsurfb.2010.05.012","volume":"79","author":"Ran","year":"2010","journal-title":"Colloids Surf. B"},{"key":"10.1016\/j.bios.2012.01.004_bib0115","doi-asserted-by":"crossref","first-page":"359","DOI":"10.1038\/nbt0402-359","volume":"20","author":"Schweitzer","year":"2002","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.bios.2012.01.004_bib0120","doi-asserted-by":"crossref","first-page":"10113","DOI":"10.1073\/pnas.170237197","volume":"97","author":"Schweitzer","year":"2000","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bios.2012.01.004_bib0125","doi-asserted-by":"crossref","first-page":"1212","DOI":"10.1002\/adma.200306661","volume":"16","author":"Shin","year":"2004","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bios.2012.01.004_bib0130","doi-asserted-by":"crossref","first-page":"4601","DOI":"10.1016\/j.bios.2011.04.043","volume":"26","author":"Su","year":"2011","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2012.01.004_bib0135","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1021\/ac0485278","volume":"77","author":"Wilson","year":"2005","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2012.01.004_bib0140","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.ab.2008.10.043","volume":"387","author":"Zhang","year":"2009","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bios.2012.01.004_bib0145","doi-asserted-by":"crossref","first-page":"6330","DOI":"10.1002\/anie.200705982","volume":"47","author":"Zhao","year":"2008","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.bios.2012.01.004_bib0150","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1016\/S0956-5663(02)00146-X","volume":"18","author":"Zhou","year":"2003","journal-title":"Biosens. Bioelectron."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095656631200022X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095656631200022X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T23:49:21Z","timestamp":1760658561000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S095656631200022X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,3]]},"references-count":30,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,3]]}},"alternative-id":["S095656631200022X"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2012.01.004","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2012,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ultrasensitive electrochemical immunosensor for HE4 based on rolling circle amplification","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2012.01.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}