{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T23:58:23Z","timestamp":1767916703566,"version":"3.49.0"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,10,1]],"date-time":"2015-10-01T00:00:00Z","timestamp":1443657600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2015,10]]},"DOI":"10.1016\/j.bios.2015.05.014","type":"journal-article","created":{"date-parts":[[2015,5,13]],"date-time":"2015-05-13T21:47:48Z","timestamp":1431553668000},"page":"362-369","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Quantum-dot biosensor for hybridization and detection of R3500Q mutation of apolipoprotein B-100 gene"],"prefix":"10.1016","volume":"72","author":[{"given":"Mohammad","family":"Mazloum-Ardakani","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roghayyeh","family":"Aghaei","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Mehdi","family":"Heidari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bios.2015.05.014_bib1","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1016\/j.trac.2008.11.012","volume":"28","author":"Algar","year":"2009","journal-title":"Trends Anal. Chem."},{"key":"10.1016\/j.bios.2015.05.014_bib2","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.bios.2015.02.024","volume":"69","author":"Amouzadeh-Tabrizi","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2015.05.014_bib3","doi-asserted-by":"crossref","first-page":"1307","DOI":"10.1016\/j.bios.2007.11.021","volume":"23","author":"Asphahani","year":"2008","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2015.05.014_bib4","series-title":"Electrochemical Methods: Fundamentals and Applications","author":"Bard","year":"2001"},{"key":"10.1016\/j.bios.2015.05.014_bib5","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.bios.2014.01.053","volume":"58","author":"Benvidi","year":"2014","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2015.05.014_bib6","doi-asserted-by":"crossref","first-page":"4403","DOI":"10.1063\/1.447218","volume":"80","author":"Brus","year":"1984","journal-title":"J. Chem. Phys"},{"key":"10.1016\/j.bios.2015.05.014_bib7","series-title":"Cell-Based Biosensors Principles and Applications","author":"Wang","year":"2010"},{"key":"10.1016\/j.bios.2015.05.014_bib8","doi-asserted-by":"crossref","first-page":"40","DOI":"10.1016\/S0958-1669(02)00282-3","volume":"13","author":"Chan","year":"2002","journal-title":"Curr. Opin. Biotechnol."},{"key":"10.1016\/j.bios.2015.05.014_bib9","doi-asserted-by":"crossref","first-page":"2351","DOI":"10.1021\/jp065099w","volume":"111","author":"Chen","year":"2007","journal-title":"J. Phys. Chem. C"},{"key":"10.1016\/j.bios.2015.05.014_bib10","doi-asserted-by":"crossref","first-page":"4225","DOI":"10.1002\/adma.200703183","volume":"20","author":"De","year":"2008","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bios.2015.05.014_bib11","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1002\/1521-4109(200103)13:3<219::AID-ELAN219>3.0.CO;2-7","volume":"13","author":"Erdem","year":"2001","journal-title":"Electroanalysis"},{"key":"10.1016\/j.bios.2015.05.014_bib12","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1007\/978-1-60761-670-2_3","volume":"627","author":"Fischer","year":"2010","journal-title":"Methods Mol. Biol."},{"key":"10.1016\/j.bios.2015.05.014_bib13","doi-asserted-by":"crossref","first-page":"7070","DOI":"10.1021\/ja017822w","volume":"124","author":"Gerion","year":"2002","journal-title":"J. Am. Chem. Soc"},{"key":"10.1016\/j.bios.2015.05.014_bib14","doi-asserted-by":"crossref","first-page":"7602","DOI":"10.1002\/anie.200800169","volume":"47","author":"Gill","year":"2008","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.bios.2015.05.014_bib15","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1002\/jcla.1037","volume":"15","author":"Horvath","year":"2001","journal-title":"J. Clin. Lab. Anal."},{"key":"10.1016\/j.bios.2015.05.014_bib16","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1016\/j.bios.2015.01.039","volume":"68","author":"Huang","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2015.05.014_bib17","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1002\/elan.200302930","volume":"16","author":"Katz","year":"2004","journal-title":"Electroanalysis"},{"key":"10.1016\/j.bios.2015.05.014_bib18","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.snb.2004.04.107","volume":"102","author":"Kim","year":"2004","journal-title":"Sens. Actuators B\u2014Chem."},{"key":"10.1016\/j.bios.2015.05.014_bib19","doi-asserted-by":"crossref","first-page":"1953","DOI":"10.1002\/adma.200500786","volume":"18","author":"Klostranec","year":"2006","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bios.2015.05.014_bib20","doi-asserted-by":"crossref","first-page":"8506","DOI":"10.1021\/nn203438u","volume":"5","author":"Kramer","year":"2011","journal-title":"ACS Nano"},{"key":"10.1016\/j.bios.2015.05.014_bib21","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/S0022-0728(79)80075-3","volume":"101","author":"Laviron","year":"1979","journal-title":"J. Electroanal. Chem. Interfacial Electrochem."},{"key":"10.1016\/j.bios.2015.05.014_bib22","doi-asserted-by":"crossref","first-page":"3281","DOI":"10.1016\/j.bios.2009.04.022","volume":"24","author":"Li","year":"2009","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2015.05.014_bib23","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1039\/B618902D","volume":"17","author":"Lin","year":"2007","journal-title":"J. Mater. Chem."},{"key":"10.1016\/j.bios.2015.05.014_bib24","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ab.2013.08.028","volume":"443","author":"Mazloum-Ardakani","year":"2013","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bios.2015.05.014_bib25","doi-asserted-by":"crossref","first-page":"917","DOI":"10.1007\/s00604-014-1186-9","volume":"181","author":"Mazloum-Ardakani","year":"2014","journal-title":"Microchim. Acta"},{"key":"10.1016\/j.bios.2015.05.014_bib26","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1007\/s11581-013-0984-0","volume":"20","author":"Mazloum-Ardakani","year":"2014","journal-title":"Ionics"},{"key":"10.1016\/j.bios.2015.05.014_bib27","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1016\/j.jelechem.2014.11.021","volume":"738","author":"Mazloum-Ardakani","year":"2015","journal-title":"J. Electroanal. Chem."},{"key":"10.1016\/j.bios.2015.05.014_bib28","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1038\/nmat1390","volume":"4","author":"Medintz","year":"2005","journal-title":"Nat. Mater."},{"key":"10.1016\/j.bios.2015.05.014_bib29","doi-asserted-by":"crossref","first-page":"8706","DOI":"10.1021\/ja00072a025","volume":"115","author":"Murrar","year":"1993","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bios.2015.05.014_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0021-9150(93)90171-P","volume":"104","author":"Myant","year":"1993","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.bios.2015.05.014_bib31","doi-asserted-by":"crossref","first-page":"4103","DOI":"10.1021\/ja0058334","volume":"123","author":"Pathak","year":"2001","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bios.2015.05.014_bib32","doi-asserted-by":"crossref","first-page":"5487","DOI":"10.1021\/nn1016132","volume":"4","author":"Prasuhn","year":"2010","journal-title":"ACS Nano"},{"key":"10.1016\/j.bios.2015.05.014_bib33","doi-asserted-by":"crossref","first-page":"1395","DOI":"10.1021\/la902499e","volume":"26","author":"Schubert","year":"2010","journal-title":"Langmuir"},{"key":"10.1016\/j.bios.2015.05.014_bib34","doi-asserted-by":"crossref","first-page":"3082","DOI":"10.1021\/ac202265a","volume":"84","author":"Sharma","year":"2012","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2015.05.014_bib35","doi-asserted-by":"crossref","first-page":"8753","DOI":"10.1021\/la401431q","volume":"29","author":"Sharma","year":"2013","journal-title":"Langmuir"},{"key":"10.1016\/j.bios.2015.05.014_bib36","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1073\/pnas.86.2.587","volume":"86","author":"Soria","year":"1989","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bios.2015.05.014_bib37","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1016\/j.jelechem.2014.01.015","volume":"717-718","author":"Taleat","year":"2014","journal-title":"J. Electroanal. Chem."},{"key":"10.1016\/j.bios.2015.05.014_bib38","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.bios.2013.11.072","volume":"55","author":"Thavanathan","year":"2014","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2015.05.014_bib39","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/0021-9150(92)90056-M","volume":"96","author":"Tybjaerg-Hansen","year":"1992","journal-title":"Atherosclerosis"},{"key":"10.1016\/j.bios.2015.05.014_bib40","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1021\/j100155a009","volume":"95","author":"Wang","year":"1991","journal-title":"J. Phys. Chem."},{"key":"10.1016\/j.bios.2015.05.014_bib41","doi-asserted-by":"crossref","first-page":"R1","DOI":"10.1088\/0957-4484\/17\/1\/R01","volume":"17","author":"Wang","year":"2006","journal-title":"Nanotechnology"},{"key":"10.1016\/j.bios.2015.05.014_bib42","doi-asserted-by":"crossref","first-page":"2368","DOI":"10.1002\/1521-3773(20020703)41:13<2368::AID-ANIE2368>3.0.CO;2-G","volume":"41","author":"Yu","year":"2002","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.bios.2015.05.014_bib43","doi-asserted-by":"crossref","first-page":"2854","DOI":"10.1021\/cm034081k","volume":"15","author":"Yu","year":"2003","journal-title":"Chem. Mater."},{"key":"10.1016\/j.bios.2015.05.014_bib44","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1007\/s00216-010-3609-8","volume":"397","author":"Zhang","year":"2010","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.bios.2015.05.014_bib45","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.bioelechem.2008.09.004","volume":"74","author":"Zhang","year":"2009","journal-title":"Bioelectrochemistry"},{"key":"10.1016\/j.bios.2015.05.014_bib46","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.bios.2015.03.030","volume":"70","author":"Zhai","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2015.05.014_bib47","doi-asserted-by":"crossref","first-page":"2790","DOI":"10.1039\/B407556K","volume":"14","author":"Zhong","year":"2004","journal-title":"J. Mater. Chem."},{"key":"10.1016\/j.bios.2015.05.014_bib48","series-title":"Handbook of Electrochemistry","author":"Zoski","year":"2007"}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095656631530110X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095656631530110X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T00:21:01Z","timestamp":1760660461000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S095656631530110X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,10]]},"references-count":48,"alternative-id":["S095656631530110X"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2015.05.014","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2015,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Quantum-dot biosensor for hybridization and detection of R3500Q mutation of apolipoprotein B-100 gene","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2015.05.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}