{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T17:47:10Z","timestamp":1791827230111,"version":"4.3.4"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,11,1]],"date-time":"2016-11-01T00:00:00Z","timestamp":1477958400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100004748","name":"Mashhad University of Medical Sciences","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004748","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2016,11]]},"DOI":"10.1016\/j.bios.2016.05.048","type":"journal-article","created":{"date-parts":[[2016,5,15]],"date-time":"2016-05-15T04:32:07Z","timestamp":1463286727000},"page":"509-514","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":146,"special_numbering":"C","title":["A novel M-shape electrochemical aptasensor for ultrasensitive detection of tetracyclines"],"prefix":"10.1016","volume":"85","author":[{"given":"Seyed Mohammad","family":"Taghdisi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Noor Mohammad","family":"Danesh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohammad","family":"Ramezani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalil","family":"Abnous","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bios.2016.05.048_bib1","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/j.snb.2015.10.039","article-title":"A novel electrochemical aptasensor based on H-shape structure of aptamer-complimentary strands conjugate for ultrasensitive detection of cocaine","volume":"224","author":"Abnous","year":"2016","journal-title":"Sens. Actuators B: Chem."},{"issue":"6","key":"10.1016\/j.bios.2016.05.048_bib2","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1039\/b301630g","article-title":"Application of ELISA in determining the fate of tetracyclines in land-applied livestock wastes","volume":"128","author":"Aga","year":"2003","journal-title":"Analyst"},{"key":"10.1016\/j.bios.2016.05.048_bib3","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1016\/j.measurement.2013.08.029","article-title":"Rapid and simultaneous determination of tetracycline and cefixime antibiotics by mean of gold nanoparticles-screen printed gold electrode and chemometrics tools","volume":"47","author":"Asadollahi-Baboli","year":"2014","journal-title":"Meas.: J. Int. Meas. Confed"},{"issue":"1","key":"10.1016\/j.bios.2016.05.048_bib4","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.bios.2012.10.063","article-title":"Sensitive electrochemical thrombin aptasensor based on gold disk microelectrode arrays","volume":"42","author":"Bai","year":"2013","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2016.05.048_bib5","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.talanta.2014.04.054","article-title":"A novel electrochemiluminescence tetracyclines sensor based on a Ru(bpy)3 2+-doped silica nanoparticles\/Nafion film modified electrode","volume":"129","author":"Chen","year":"2014","journal-title":"Talanta"},{"issue":"1\u20132","key":"10.1016\/j.bios.2016.05.048_bib6","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/S0021-9673(02)01446-2","article-title":"Validation of a high-performance liquid chromatography method for the determination of oxytetracycline, tetracycline, chlortetracycline and doxycycline in bovine milk and muscle","volume":"987","author":"Cinquina","year":"2003","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.bios.2016.05.048_bib7","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.foodchem.2015.05.079","article-title":"Colorimetric and fluorescence quenching aptasensors for detection of streptomycin in blood serum and milk based on double-stranded DNA and gold nanoparticles","volume":"190","author":"Emrani","year":"2016","journal-title":"Food Chem."},{"key":"10.1016\/j.bios.2016.05.048_bib8","unstructured":"Commission Regulation No. 508\/99.,\u00a01999. Off. J. Eur. Commun., No. L609."},{"key":"10.1016\/j.bios.2016.05.048_bib9","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.talanta.2014.01.002","article-title":"Simple and novel electrochemical sensor for the determination of tetracycline based on iron\/zinc cations-exchanged montmorillonite catalyst","volume":"121","author":"Gan","year":"2014","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2016.05.048_bib10","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1016\/j.bios.2015.11.043","article-title":"A sensitive aptasensor for colorimetric detection of adenosine triphosphate based on the protective effect of ATP-aptamer complexes on unmodified gold nanoparticles","volume":"78","author":"Huo","year":"2016","journal-title":"Biosens. Bioelectron."},{"issue":"10","key":"10.1016\/j.bios.2016.05.048_bib11","doi-asserted-by":"crossref","first-page":"959","DOI":"10.3923\/ijps.2010.959.962","article-title":"Antimicrobial screening of commercial eggs and determination of tetracycline residue using two microbiological methods. International","volume":"9","author":"Idowu","year":"2010","journal-title":"J. Poult. Sci."},{"issue":"2","key":"10.1016\/j.bios.2016.05.048_bib12","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1016\/j.aca.2008.08.003","article-title":"Quantitative detection of tetracycline residues in honey by a simple sensitive immunoassay","volume":"626","author":"Jeon","year":"2008","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.bios.2016.05.048_bib13","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1016\/j.foodchem.2015.07.152","article-title":"Detection of ochratoxin A (OTA) in coffee using chemiluminescence resonance energy transfer (CRET) aptasensor","volume":"194","author":"Jo","year":"2016","journal-title":"Food Chem."},{"issue":"3","key":"10.1016\/j.bios.2016.05.048_bib14","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.jpba.2008.01.036","article-title":"Capillary electrophoretic method for the simultaneous determination of tetracycline residues in fish samples","volume":"47","author":"Kowalski","year":"2008","journal-title":"J. Pharm. Biomed. Anal."},{"issue":"8","key":"10.1016\/j.bios.2016.05.048_bib15","doi-asserted-by":"crossref","first-page":"3372","DOI":"10.1021\/jf9911794","article-title":"A group-specific microbiological test for the detection of tetracycline residues in raw milk","volume":"48","author":"Kurittu","year":"2000","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bios.2016.05.048_bib16","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.bios.2015.09.066","article-title":"A sensitive and label-free photoelectrochemical aptasensor using Co-doped ZnO diluted magnetic semiconductor nanoparticles","volume":"77","author":"Li","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2016.05.048_bib17","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/j.bios.2015.11.089","article-title":"Determination of cell metabolite VEGF165 and dynamic analysis of protein-DNA interactions by combination of microfluidic technique and luminescent switch-on probe","volume":"79","author":"Lin","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2016.05.048_bib18","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.bios.2013.08.059","article-title":"Improving sensitivity of gold nanoparticle based fluorescence quenching and colorimetric aptasensor by using water resuspended gold nanoparticle","volume":"52","author":"Liu","year":"2014","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2016.05.048_bib19","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1016\/j.foodcont.2015.01.005","article-title":"A novel colorimetric aptasensor using cysteamine-stabilized gold nanoparticles as probe for rapid and specific detection of tetracycline in raw milk","volume":"54","author":"Luo","year":"2015","journal-title":"Food Control"},{"key":"10.1016\/j.bios.2016.05.048_bib20","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.snb.2015.05.106","article-title":"A colorimetric aptasensor for chloramphenicol in fish based on double-stranded DNA antibody labeled enzyme-linked polymer nanotracers for signal amplification","volume":"220","author":"Miao","year":"2015","journal-title":"Sens. Actuators, B: Chem."},{"key":"10.1016\/j.bios.2016.05.048_bib21","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/j.bios.2014.12.052","article-title":"Nanomaterial-based cocaine aptasensors","volume":"68","author":"Mokhtarzadeh","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2016.05.048_bib22","doi-asserted-by":"crossref","first-page":"1200","DOI":"10.1016\/j.proeng.2010.09.327","article-title":"New potentiometric sensors based on two competitive recognition sites for determining tetracycline residues using flow-through system","author":"Moreira","year":"2010","journal-title":"Procedia Eng."},{"issue":"1","key":"10.1016\/j.bios.2016.05.048_bib23","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1007\/s12161-011-9225-1","article-title":"Matrix solid-phase dispersion extraction and capillary electrophoresis determination of tetracycline residues in milk","volume":"5","author":"Mu","year":"2012","journal-title":"Food Anal. Methods"},{"issue":"15","key":"10.1016\/j.bios.2016.05.048_bib24","doi-asserted-by":"crossref","first-page":"7245","DOI":"10.1016\/j.bmc.2008.06.033","article-title":"Single-stranded DNA aptamers specific for antibiotics tetracyclines","volume":"16","author":"Niazi","year":"2008","journal-title":"Bioorg. Med. Chem."},{"key":"10.1016\/j.bios.2016.05.048_bib25","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.bios.2015.03.040","article-title":"A novel colorimetric triple-helix molecular switch aptasensor for ultrasensitive detection of tetracycline","volume":"70","author":"Ramezani","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2016.05.048_bib26","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1016\/j.bios.2015.10.069","article-title":"Generation and characterization of quinolone-specific DNA aptamers suitable for water monitoring","volume":"77","author":"Reinemann","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2016.05.048_bib27","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/cc11441","article-title":"Therapeutic and toxic blood concentrations of nearly 1,000 drugs and other xenobiotics","volume":"16","author":"Schulz","year":"2012","journal-title":"Crit. Care"},{"issue":"4","key":"10.1016\/j.bios.2016.05.048_bib28","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.jchromb.2008.12.042","article-title":"Carrier mediated hollow fiber liquid phase microextraction combined with HPLC-UV for preconcentration and determination of some tetracycline antibiotics","volume":"877","author":"Shariati","year":"2009","journal-title":"J. Chromatogr. B: Anal. Technol. Biomed. Life Sci."},{"key":"10.1016\/j.bios.2016.05.048_bib29","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1016\/j.bios.2015.09.008","article-title":"A fluorescent aptasensor for amplified label-free detection of adenosine triphosphate based on core\u2013shell Ag@SiO2 nanoparticles","volume":"77","author":"Song","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2016.05.048_bib30","doi-asserted-by":"crossref","first-page":"532","DOI":"10.1016\/j.bios.2016.02.029","article-title":"A novel electrochemical aptasensor based on Y-shape structure of dual-aptamer-complementary strand conjugate for ultrasensitive detection of myoglobin","volume":"80","author":"Taghdisi","year":"2016","journal-title":"Biosens. Bioelectron."},{"issue":"3","key":"10.1016\/j.bios.2016.05.048_bib31","doi-asserted-by":"crossref","first-page":"1236","DOI":"10.1016\/j.etap.2014.04.020","article-title":"Ultrasensitive detection of lead (II) based on fluorescent aptamer-functionalized carbon nanotubes","volume":"37","author":"Taghdisi","year":"2014","journal-title":"Environ. Toxicol. Pharmacol."},{"key":"10.1016\/j.bios.2016.05.048_bib32","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/j.bios.2013.07.011","article-title":"Determination of tetracycline in milk by using nucleotide\/lanthanide coordination polymer-based ternary complex","volume":"50","author":"Tan","year":"2013","journal-title":"Biosens. Bioelectron."},{"issue":"23\u201324","key":"10.1016\/j.bios.2016.05.048_bib33","doi-asserted-by":"crossref","first-page":"4254","DOI":"10.1002\/jssc.200900415","article-title":"Simultaneous determination of five tetracycline and macrolide antibiotics in feeds using HPCE","volume":"32","author":"Tong","year":"2009","journal-title":"J. Sep. Sci."},{"issue":"1\u20132","key":"10.1016\/j.bios.2016.05.048_bib34","first-page":"105","article-title":"Flow injection chemiluminescence determination of tetracycline","volume":"541","author":"Townshend","year":"2005","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.bios.2016.05.048_bib35","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.bios.2015.11.015","article-title":"Aptamer induced assembly of fluorescent nitrogen-doped carbon dots on gold nanoparticles for sensitive detection of AFB1","volume":"78","author":"Wang","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2016.05.048_bib36","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/j.foodcont.2014.10.003","article-title":"Aptamer-based fluorescence biosensor for chloramphenicol determination using upconversion nanoparticles","volume":"50","author":"Wu","year":"2015","journal-title":"Food Control"},{"key":"10.1016\/j.bios.2016.05.048_bib37","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/j.snb.2014.02.036","article-title":"Target-induced strand release and thionine-decorated gold nanoparticle amplification labels for sensitive electrochemical aptamer-based sensing of small molecules","volume":"197","author":"Yang","year":"2014","journal-title":"Sens. Actuators, B: Chem."},{"key":"10.1016\/j.bios.2016.05.048_bib38","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1016\/j.bios.2015.09.050","article-title":"Label free electrochemical aptasensor for ultrasensitive detection of ractopamine","volume":"77","author":"Yang","year":"2016","journal-title":"Biosens. Bioelectron."},{"issue":"2","key":"10.1016\/j.bios.2016.05.048_bib39","doi-asserted-by":"crossref","first-page":"723","DOI":"10.1007\/s00604-015-1718-y","article-title":"Electrochemical aptasensor for tetracycline using a screen-printed carbon electrode modified with an alginate film containing reduced graphene oxide and magnetite (Fe3O4) nanoparticles","volume":"183","author":"Zhan","year":"2015","journal-title":"Microchim. Acta"},{"key":"10.1016\/j.bios.2016.05.048_bib40","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.bios.2014.11.024","article-title":"RNA aptamer based electrochemical biosensor for sensitive and selective detection of cAMP","volume":"66","author":"Zhao","year":"2015","journal-title":"Biosens. Bioelectron."},{"issue":"12","key":"10.1016\/j.bios.2016.05.048_bib41","doi-asserted-by":"crossref","first-page":"2949","DOI":"10.1007\/s00216-014-7705-z","article-title":"Exonuclease i aided enzyme-linked aptamer assay for small-molecule detection","volume":"406","author":"Zhao","year":"2014","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.bios.2016.05.048_bib42","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.jct.2012.08.007","article-title":"Measurement and correlation of solubility of Tetracycline hydrochloride in six organic solvents","volume":"57","author":"Zhao","year":"2013","journal-title":"J. Chem. Thermodyn."},{"issue":"8","key":"10.1016\/j.bios.2016.05.048_bib43","doi-asserted-by":"crossref","first-page":"3554","DOI":"10.1021\/ac300690r","article-title":"Label-free fluorescent detection of ions, proteins, and small molecules using structure-switching aptamers, SYBR Gold, and exonuclease I","volume":"84","author":"Zheng","year":"2012","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2016.05.048_bib44","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1016\/j.bios.2014.12.022","article-title":"A label-free electrochemical aptasensor based on the catalysis of manganese porphyrins for detection of thrombin","volume":"66","author":"Zheng","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2016.05.048_bib46","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.foodchem.2014.04.058","article-title":"An electrochemical aptasensor based on gold nanoparticles dotted graphene modified glassy carbon electrode for label-free detection of bisphenol A in milk samples","volume":"162","author":"Zhou","year":"2014","journal-title":"Food Chem."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566316304791?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566316304791?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T00:30:56Z","timestamp":1760661056000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566316304791"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,11]]},"references-count":45,"alternative-id":["S0956566316304791"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2016.05.048","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2016,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A novel M-shape electrochemical aptasensor for ultrasensitive detection of tetracyclines","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2016.05.048","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}]}}