{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T04:32:27Z","timestamp":1790742747183,"version":"4.1.0"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,4,1]],"date-time":"2020-04-01T00:00:00Z","timestamp":1585699200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2020,4]]},"DOI":"10.1016\/j.bios.2020.112028","type":"journal-article","created":{"date-parts":[[2020,1,21]],"date-time":"2020-01-21T02:29:58Z","timestamp":1579573798000},"page":"112028","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":70,"special_numbering":"C","title":["Micro-needle implantable electrochemical oxygen sensor: ex-vivo and in-vivo studies"],"prefix":"10.1016","volume":"153","author":[{"given":"Lourdes","family":"Rivas","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Samuel","family":"Dulay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandrine","family":"Miserere","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Laura","family":"Pla","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sergio Berd\u00fan","family":"Marin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johanna","family":"Parra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elisenda","family":"Eixarch","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduard","family":"Gratac\u00f3s","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00edriam","family":"Illa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00f2nica","family":"Mir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Samitier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bios.2020.112028_bib1","doi-asserted-by":"crossref","first-page":"4028","DOI":"10.1039\/c1an15324b","article-title":"An in vitro characterisation comparing carbon paste and Pt microelectrodes for real-time detection of brain tissue oxygen","volume":"136","author":"Bolger","year":"2011","journal-title":"Analyst"},{"key":"10.1016\/j.bios.2020.112028_bib2","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.jneumeth.2010.11.013","article-title":"Characterisation of carbon paste electrodes for real-time amperometric monitoring of brain tissue oxygen","volume":"195","author":"Bolger","year":"2011","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.bios.2020.112028_bib3","first-page":"41","article-title":"Monitor and control of blood and tissue oxygen tensions","volume":"2","author":"Clark","year":"1956","journal-title":"Trans. Am. Soc. Artif. Intern. Organs"},{"key":"10.1016\/j.bios.2020.112028_bib4","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1152\/jappl.1953.6.3.189","article-title":"Continuous recording of blood oxygen tensions by polarography","volume":"6","author":"Clark","year":"1953","journal-title":"J. Appl. Physiol."},{"issue":"3","key":"10.1016\/j.bios.2020.112028_bib5","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1183\/20734735.001415","article-title":"Relating oxygen partial pressure, saturation and content: the haemoglobin\u2013oxygen dissociation curve","volume":"11","author":"Collins","year":"2015","journal-title":"Breathe"},{"key":"10.1016\/j.bios.2020.112028_bib6","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.bioelechem.2017.09.010","article-title":"In vitro development and in vivo application of a platinum-based electrochemical device for continuous measurements of peripheral tissue oxygen","volume":"119","author":"Finnerty","year":"2018","journal-title":"Bioelectrochemistry"},{"key":"10.1016\/j.bios.2020.112028_bib7","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0376-7388(96)00155-X","article-title":"Recent advances in perfluorinated ionomer membranes: structure, properties and applications","volume":"120","author":"Heitner-Wirguin","year":"1996","journal-title":"J. Membr. Sci."},{"key":"10.1016\/j.bios.2020.112028_bib9","doi-asserted-by":"crossref","first-page":"2247","DOI":"10.1149\/1.2096247","article-title":"Oxygen reduction at nafion film-coated platinum electrodes: transport and kinetics","volume":"135","author":"Lawson","year":"1988","journal-title":"J. Electrochem. Soc."},{"key":"10.1016\/j.bios.2020.112028_bib10","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.snb.2007.06.008","article-title":"Needle-type dissolved oxygen microelectrode array sensors for in situ measurements","volume":"128","author":"Lee","year":"2007","journal-title":"Sensor. Actuator. B Chem."},{"issue":"5","key":"10.1016\/j.bios.2020.112028_bib11","doi-asserted-by":"crossref","first-page":"2392","DOI":"10.1021\/acs.chemrev.7b00220","article-title":"O2 reduction in enzymatic biofuel cells","volume":"118","author":"Mano","year":"2018","journal-title":"Chem. Rev."},{"key":"10.1016\/j.bios.2020.112028_bib12","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1113\/jphysiol.1990.sp017969","article-title":"Effects of hypoxia upon contractions evoked in isolated rabbit pulmonary artery by potassium and noradrenaline","volume":"422","author":"Marriott","year":"1990","journal-title":"J. Physiol."},{"key":"10.1016\/j.bios.2020.112028_bib13","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1149\/1.2409016","article-title":"Some milestones in the 50-year history of electrochemical oxygen sensor development","volume":"2","author":"Nei","year":"2007","journal-title":"ECS Trans"},{"key":"10.1016\/j.bios.2020.112028_bib14","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1002\/elan.201600653","article-title":"Long\u2013term drifts in sensitivity caused by biofouling of an amperometric oxygen sensor","volume":"29","author":"Patrick","year":"2017","journal-title":"Electroanalysis"},{"key":"10.1016\/j.bios.2020.112028_bib16","series-title":"Atlas of Electrochemical Equilibria in Aqueous Solutions","author":"Pourbaix","year":"1966"},{"key":"10.1016\/j.bios.2020.112028_bib17","author":"PreSens"},{"key":"10.1016\/j.bios.2020.112028_bib19","series-title":"Clinical Aspects of O2 Transport and Tissue Oxygenation","author":"Reinhart","year":"1989"},{"key":"10.1016\/j.bios.2020.112028_bib20","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1152\/jappl.1999.86.1.306","article-title":"Acute response of the lung mechanics of the rabbit to hypoxia","volume":"86","author":"Sakai","year":"1999","journal-title":"J. Appl. Physiol."},{"key":"10.1016\/j.bios.2020.112028_bib21","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1007\/BF01637680","article-title":"History of blood gas analysis. IV. Leland Clark's oxygen electrode","volume":"2","author":"Severinghaus","year":"1986","journal-title":"J. Clin. Monit."},{"key":"10.1016\/j.bios.2020.112028_bib22","doi-asserted-by":"crossref","first-page":"613","DOI":"10.1016\/j.redox.2016.12.035","article-title":"Hydrogen peroxide as a central redox signaling molecule in physiological oxidative stress: oxidative stress","volume":"11","author":"Sies","year":"2017","journal-title":"Redox Biology"},{"key":"10.1016\/j.bios.2020.112028_bib23","series-title":"Trends in Bioelectroanalysis","first-page":"263","article-title":"Trends in electrochemical sensing of blood gases","author":"van der Weerd","year":"2017"},{"key":"10.1016\/j.bios.2020.112028_bib29","series-title":"Respiratory physiology: the essentials","author":"West","year":"2016"},{"key":"10.1016\/j.bios.2020.112028_bib24","doi-asserted-by":"crossref","first-page":"1848","DOI":"10.1021\/ar300359w","article-title":"Platinum-based oxygen reduction electrocatalysts","volume":"46","author":"Wu","year":"2013","journal-title":"Acc. Chem. Res."},{"key":"10.1016\/j.bios.2020.112028_bib25","doi-asserted-by":"crossref","first-page":"342","DOI":"10.1016\/j.snb.2005.02.014","article-title":"Fabrication of miniature Clark oxygen sensor integrated with microstructure","volume":"110","author":"Wu","year":"2005","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.bios.2020.112028_bib26","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1021\/acs.analchem.6b04308","article-title":"In vivo analysis with electrochemical sensors and biosensors","volume":"89","author":"Xiao","year":"2017","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2020.112028_bib27","doi-asserted-by":"crossref","first-page":"7152","DOI":"10.1016\/S1452-3981(23)10957-6","article-title":"Amperometric gas detection: a review","volume":"9","author":"Xiong","year":"2014","journal-title":"Int. J. Electrochem. Sci."},{"key":"10.1016\/j.bios.2020.112028_bib28","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1021\/ac00001a005","article-title":"Simultaneous electrochemical measurements of oxygen and dopamine in vivo","volume":"63","author":"Zimmerman","year":"1991","journal-title":"Anal. Chem."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566320300257?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566320300257?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T01:04:53Z","timestamp":1760663093000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566320300257"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4]]},"references-count":26,"alternative-id":["S0956566320300257"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2020.112028","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Micro-needle implantable electrochemical oxygen sensor: ex-vivo and in-vivo studies","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2020.112028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"112028"}}