{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T22:30:28Z","timestamp":1785882628806,"version":"3.56.0"},"reference-count":53,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003710","name":"Korea Health Industry Development Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003710","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.bios.2020.112281","type":"journal-article","created":{"date-parts":[[2020,5,10]],"date-time":"2020-05-10T23:15:03Z","timestamp":1589152503000},"page":"112281","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":39,"special_numbering":"C","title":["Nanochannel-driven rapid capture of sub-nanogram level biomarkers for painless preeclampsia diagnosis"],"prefix":"10.1016","volume":"163","author":[{"given":"Ye-Eun","family":"Kang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keum-Yong","family":"Seong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang-Gu","family":"Yim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yechan","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Min","family":"An","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Chul","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyujung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beum-Soo","family":"An","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyu-Sup","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung Yun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bios.2020.112281_bib1","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/S0002-9378(99)70150-X","volume":"180","author":"Acromite","year":"1999","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.bios.2020.112281_bib2","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1016\/j.actbio.2017.11.050","volume":"67","author":"An","year":"2018","journal-title":"Acta Biomater."},{"key":"10.1016\/j.bios.2020.112281_bib3","doi-asserted-by":"crossref","first-page":"S42","DOI":"10.1016\/j.placenta.2011.11.021","volume":"33","author":"Anderson","year":"2012","journal-title":"Placenta"},{"key":"10.1016\/j.bios.2020.112281_bib4","doi-asserted-by":"crossref","first-page":"266. e1","DOI":"10.1016\/j.ajog.2008.06.069","volume":"199","author":"Baumann","year":"2008","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.bios.2020.112281_bib5","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1002\/elan.201800630","volume":"31","author":"Bollella","year":"2019","journal-title":"Electroanalysis"},{"key":"10.1016\/j.bios.2020.112281_bib6","doi-asserted-by":"crossref","first-page":"402","DOI":"10.1097\/AOG.0b013e3181e9322a","volume":"116","author":"Bujold","year":"2010","journal-title":"Obstet. Gynecol."},{"key":"10.1016\/j.bios.2020.112281_bib7","doi-asserted-by":"crossref","first-page":"1702243","DOI":"10.1002\/adma.201702243","volume":"29","author":"Chang","year":"2017","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bios.2020.112281_bib8","doi-asserted-by":"crossref","first-page":"Q3159","DOI":"10.1149\/2.0241807jss","volume":"7","author":"Chinnadayyala","year":"2018","journal-title":"ECS J. Solid State Sci. Technol."},{"key":"10.1016\/j.bios.2020.112281_bib9","doi-asserted-by":"crossref","first-page":"1701264","DOI":"10.1002\/adhm.201701264","volume":"7","author":"Ciui","year":"2018","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.bios.2020.112281_bib10","doi-asserted-by":"crossref","first-page":"9572","DOI":"10.1016\/j.biomaterials.2013.08.078","volume":"34","author":"Coffey","year":"2013","journal-title":"Biomaterials"},{"key":"10.1016\/j.bios.2020.112281_bib11","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.biomaterials.2018.03.039","volume":"170","author":"Coffey","year":"2018","journal-title":"Biomaterials"},{"key":"10.1016\/j.bios.2020.112281_bib12","doi-asserted-by":"crossref","first-page":"2655","DOI":"10.1039\/c0lc00068j","volume":"10","author":"Corrie","year":"2010","journal-title":"Lab Chip"},{"key":"10.1016\/j.bios.2020.112281_bib13","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1016\/j.jbiomech.2003.12.010","volume":"37","author":"Davis","year":"2004","journal-title":"J. Biomech."},{"key":"10.1016\/j.bios.2020.112281_bib14","doi-asserted-by":"crossref","first-page":"299","DOI":"10.1016\/j.ijpharm.2018.12.089","volume":"558","author":"Gholami","year":"2019","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.bios.2020.112281_bib15","doi-asserted-by":"crossref","first-page":"9191","DOI":"10.1021\/ac7016713","volume":"79","author":"Gonzalez-Techera","year":"2007","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2020.112281_bib16","doi-asserted-by":"crossref","first-page":"1072","DOI":"10.1021\/acssensors.9b00288","volume":"4","author":"Gowers","year":"2019","journal-title":"ACS Sens."},{"key":"10.1016\/j.bios.2020.112281_bib17","doi-asserted-by":"crossref","first-page":"153","DOI":"10.5625\/lar.2010.26.2.153","volume":"26","author":"Han","year":"2010","journal-title":"Lab. Anim. Res."},{"key":"10.1016\/j.bios.2020.112281_bib18","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1016\/j.actbio.2006.07.007","volume":"3","author":"Hoess","year":"2007","journal-title":"Acta Biomater."},{"key":"10.1016\/j.bios.2020.112281_bib19","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1016\/S1452-3981(23)04860-5","volume":"10","author":"Hwa","year":"2015","journal-title":"Int. J. Electrochem. Sci."},{"key":"10.1016\/j.bios.2020.112281_bib20","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1159\/000088499","volume":"211","author":"Jacobi","year":"2005","journal-title":"Dermatology"},{"key":"10.1016\/j.bios.2020.112281_bib21","doi-asserted-by":"crossref","first-page":"1804298","DOI":"10.1002\/smll.201804298","volume":"15","author":"Jin","year":"2019","journal-title":"Small"},{"key":"10.1016\/j.bios.2020.112281_bib22","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1002\/adhm.201500012","volume":"4","author":"Keum","year":"2015","journal-title":"Adv. Healthc. Mater."},{"key":"10.1016\/j.bios.2020.112281_bib23","doi-asserted-by":"crossref","first-page":"1245","DOI":"10.1210\/endo-90-5-1245","volume":"90","author":"Kirdani","year":"1972","journal-title":"Endocrinology"},{"key":"10.1016\/j.bios.2020.112281_bib24","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/S0065-2423(01)36027-4","volume":"36","author":"Kobayashi","year":"2001","journal-title":"Adv. Clin. Chem."},{"key":"10.1016\/j.bios.2020.112281_bib25","doi-asserted-by":"crossref","first-page":"1116","DOI":"10.1021\/ac0257391","volume":"75","author":"Kojima","year":"2003","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2020.112281_bib26","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1081\/PRG-120028286","volume":"23","author":"Krauss","year":"2004","journal-title":"Hypertens. Pregnancy"},{"key":"10.1016\/j.bios.2020.112281_bib27","first-page":"344","volume":"83","author":"Laivuori","year":"1998","journal-title":"J. Clin. Endocrinol. Metab."},{"key":"10.1016\/j.bios.2020.112281_bib28","doi-asserted-by":"crossref","first-page":"115","DOI":"10.5625\/lar.2012.28.2.115","volume":"28","author":"Lee","year":"2012","journal-title":"Lab. Anim. Res."},{"key":"10.1016\/j.bios.2020.112281_bib29","doi-asserted-by":"crossref","first-page":"7487","DOI":"10.1021\/cr500002z","volume":"114","author":"Lee","year":"2014","journal-title":"Chem. Rev."},{"key":"10.1016\/j.bios.2020.112281_bib30","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.biomaterials.2015.04.040","volume":"59","author":"Li","year":"2015","journal-title":"Biomaterials"},{"key":"10.1016\/j.bios.2020.112281_bib31","doi-asserted-by":"crossref","first-page":"3286","DOI":"10.1039\/C5LC00669D","volume":"15","author":"Li","year":"2015","journal-title":"Lab Chip"},{"key":"10.1016\/j.bios.2020.112281_bib32","doi-asserted-by":"crossref","first-page":"4809","DOI":"10.1021\/acsami.8b18981","volume":"11","author":"Liu","year":"2019","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.bios.2020.112281_bib33","doi-asserted-by":"crossref","first-page":"2835","DOI":"10.1021\/ac048505l","volume":"77","author":"Mak","year":"2005","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2020.112281_bib34","doi-asserted-by":"crossref","first-page":"eaar2227","DOI":"10.1126\/scitranslmed.aar2227","volume":"10","author":"Mandal","year":"2018","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.bios.2020.112281_bib35","doi-asserted-by":"crossref","first-page":"1378","DOI":"10.1093\/clinchem\/41.9.1378","volume":"41","author":"Meyerhoff","year":"1995","journal-title":"Clin. Chem."},{"key":"10.1016\/j.bios.2020.112281_bib36","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1016\/j.bios.2017.01.016","volume":"91","author":"Mohan","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2020.112281_bib37","doi-asserted-by":"crossref","first-page":"3262","DOI":"10.1021\/ac2034387","volume":"84","author":"Muller","year":"2012","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2020.112281_bib39","doi-asserted-by":"crossref","first-page":"199","DOI":"10.2217\/whe.15.95","volume":"12","author":"O'Gorman","year":"2016","journal-title":"Wom. Health"},{"key":"10.1016\/j.bios.2020.112281_bib38","doi-asserted-by":"crossref","first-page":"103. e1","DOI":"10.1016\/j.ajog.2015.08.034","volume":"214","author":"O\u2019Gorman","year":"2016","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.bios.2020.112281_bib40","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1002\/pd.4397","volume":"34","author":"Poon","year":"2014","journal-title":"Prenat. Diagn."},{"key":"10.1016\/j.bios.2020.112281_bib41","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1126\/science.1111726","volume":"308","author":"Redman","year":"2005","journal-title":"Science"},{"key":"10.1016\/j.bios.2020.112281_bib42","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/S0140-6736(00)03577-7","volume":"357","author":"Roberts","year":"2001","journal-title":"Lancet"},{"key":"10.1016\/j.bios.2020.112281_bib43","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1016\/j.placenta.2008.11.009","volume":"30","author":"Roberts","year":"2009","journal-title":"Placenta"},{"key":"10.1016\/j.bios.2020.112281_bib44","doi-asserted-by":"crossref","first-page":"10520","DOI":"10.1021\/ac503823p","volume":"86","author":"Romanyuk","year":"2014","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2020.112281_bib45","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1016\/S0165-9936(02)00401-6","volume":"21","author":"Ronkainen-Matsuno","year":"2002","journal-title":"TrAC Trends Anal. Chem."},{"key":"10.1016\/j.bios.2020.112281_bib46","doi-asserted-by":"crossref","first-page":"48","DOI":"10.1016\/j.jconrel.2017.03.041","volume":"265","author":"Seong","year":"2017","journal-title":"J. Contr. Release"},{"key":"10.1016\/j.bios.2020.112281_bib47","first-page":"2681","volume":"17","author":"Shin","year":"2018","journal-title":"Mol. Med. Rep."},{"key":"10.1016\/j.bios.2020.112281_bib48","doi-asserted-by":"crossref","first-page":"40. e41","DOI":"10.1016\/j.ajog.2009.07.025","volume":"202","author":"Sunderji","year":"2010","journal-title":"Am. J. Obstet. Gynecol."},{"key":"10.1016\/j.bios.2020.112281_bib49","doi-asserted-by":"crossref","first-page":"27683","DOI":"10.1038\/srep27683","volume":"6","author":"Tian","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bios.2020.112281_bib50","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1093\/ije\/dyg094","volume":"32","author":"Troisi","year":"2003","journal-title":"Int. J. Epidemiol."},{"key":"10.1016\/j.bios.2020.112281_bib51","doi-asserted-by":"crossref","first-page":"642","DOI":"10.1038\/nm1429","volume":"12","author":"Venkatesha","year":"2006","journal-title":"Nat. Med."},{"key":"10.1016\/j.bios.2020.112281_bib52","doi-asserted-by":"crossref","first-page":"23017","DOI":"10.1039\/c2jm34459a","volume":"22","author":"Yang","year":"2012","journal-title":"J. Mater. Chem."},{"key":"10.1016\/j.bios.2020.112281_bib53","doi-asserted-by":"crossref","first-page":"4377","DOI":"10.1016\/j.electacta.2009.12.054","volume":"55","author":"Zaraska","year":"2010","journal-title":"Electrochim. Acta"}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566320302761?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566320302761?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T01:09:14Z","timestamp":1760663354000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566320302761"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":53,"alternative-id":["S0956566320302761"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2020.112281","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Nanochannel-driven rapid capture of sub-nanogram level biomarkers for painless preeclampsia diagnosis","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2020.112281","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"112281"}}