{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,14]],"date-time":"2026-03-14T02:42:20Z","timestamp":1773456140889,"version":"3.50.1"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2020,9,1]],"date-time":"2020-09-01T00:00:00Z","timestamp":1598918400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2020,9]]},"DOI":"10.1016\/j.bios.2020.112315","type":"journal-article","created":{"date-parts":[[2020,5,23]],"date-time":"2020-05-23T11:36:55Z","timestamp":1590233815000},"page":"112315","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["An EEG system to detect brain signals from multiple adult zebrafish"],"prefix":"10.1016","volume":"164","author":[{"given":"Yuhyun","family":"Lee","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kyeong Jae","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jae-Won","family":"Jang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang-im","family":"Lee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sohee","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.bios.2020.112315_bib1","series-title":"Introduction to EEG- and Speech-Based Emotion Recognition","first-page":"1","article-title":"Technical aspects of brain rhythms and speech parameters","author":"Abhang","year":"2016"},{"key":"10.1016\/j.bios.2020.112315_bib2","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0054166","article-title":"Validation of the zebrafish pentylenetetrazol seizure model: locomotor versus electrographic responses to antiepileptic drugs","volume":"8","author":"Afrikanova","year":"2013","journal-title":"PloS One"},{"issue":"2","key":"10.1016\/j.bios.2020.112315_bib3","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0013-4694(98)00051-0","article-title":"Electrophysiological correlates of sleep delta waves","volume":"107","author":"Amzica","year":"1998","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.bios.2020.112315_bib4","doi-asserted-by":"crossref","first-page":"2410","DOI":"10.1038\/ncomms3410","article-title":"Drug screening in Scn1a zebrafish mutant identifies clemizole as a potential Dravet syndrome treatment","volume":"4","author":"Baraban","year":"2013","journal-title":"Nat. Commun."},{"issue":"3","key":"10.1016\/j.bios.2020.112315_bib5","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/j.neuroscience.2004.11.031","article-title":"Pentylenetetrazole induced changes in zebrafish behavior, neural activity and c-fos expression","volume":"131","author":"Baraban","year":"2005","journal-title":"Neuroscience"},{"key":"10.1016\/j.bios.2020.112315_bib6","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1179\/147683008X301478","article-title":"Influence of phosphatidylserine on cognitive performance and cortical activity after induced stress","volume":"11","author":"Baumeister","year":"2008","journal-title":"Nutr. Neurosci."},{"key":"10.1016\/j.bios.2020.112315_bib7","first-page":"773","article-title":"Identification of compounds with anti-convulsant properties in a zebrafish model of epileptic seizures","volume":"5","author":"Baxendale","year":"2012","journal-title":"DMM Dis. Model. Mech."},{"key":"10.1016\/j.bios.2020.112315_bib8","series-title":"Neuroscience","author":"Bear","year":"2007"},{"issue":"1","key":"10.1016\/j.bios.2020.112315_bib9","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1016\/j.eplepsyres.2007.03.015","article-title":"Zebrafish offer the potential for a primary screen to identify a wide variety of potential anticonvulsants","volume":"75","author":"Berghmans","year":"2007","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.bios.2020.112315_bib10","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pcbi.1002902","article-title":"Chapter 15: disease gene prioritization","volume":"9","author":"Bromberg","year":"2013","journal-title":"PLoS Comput. Biol."},{"key":"10.1016\/j.bios.2020.112315_bib12","doi-asserted-by":"crossref","first-page":"962","DOI":"10.1111\/j.1528-1167.2012.03446.x","article-title":"Mapping the availability, price, and affordability of antiepileptic drugs in 46 countries","volume":"53","author":"Cameron","year":"2012","journal-title":"Epilepsia"},{"key":"10.1016\/j.bios.2020.112315_bib13","doi-asserted-by":"crossref","first-page":"3099","DOI":"10.1038\/s41598-017-03482-6","article-title":"Zebrafish as an animal model in epilepsy studies with multichannel EEG recordings","volume":"7","author":"Cho","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bios.2020.112315_bib14","doi-asserted-by":"crossref","first-page":"2065","DOI":"10.1152\/jn.00538.2015","article-title":"Zebrafish needle EMG: a new tool for high-throughput drug screens","volume":"114","author":"Cho","year":"2015","journal-title":"J. Neurophysiol."},{"key":"10.1016\/j.bios.2020.112315_bib15","article-title":"Gavaging adult zebrafish","volume":"1\u20134","author":"Collymore","year":"2013","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.bios.2020.112315_bib16","first-page":"198","article-title":"Efficacy and safety of 5 anesthetics in adult zebrafish (Danio rerio)","volume":"53","author":"Collymore","year":"2014","journal-title":"J. Am. Assoc. Lab. Anim. Sci."},{"key":"10.1016\/j.bios.2020.112315_bib17","series-title":"Models of Seizures and Epilepsy: Second Edition","article-title":"Zebrafish models of epilepsy and epileptic seizures","author":"Copmans","year":"2017"},{"key":"10.1016\/j.bios.2020.112315_bib11","article-title":"Behavioral and physiological analysis in a zebrafish model of epilepsy","author":"Dabacan","year":"2020","journal-title":"Journal of Visualized Experiments"},{"key":"10.1016\/j.bios.2020.112315_bib19","doi-asserted-by":"crossref","DOI":"10.1038\/s41467-017-02404-4","article-title":"Brain activity patterns in high-throughput electrophysiology screen predict both drug efficacies and side effects","volume":"9","author":"Eimon","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bios.2020.112315_bib20","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1007\/978-94-017-8914-1_1","article-title":"How can we identify ictal and interictal abnormal activity?","volume":"813","author":"Fisher","year":"2014","journal-title":"Adv. Exp. Med. Biol."},{"key":"10.1016\/j.bios.2020.112315_bib21","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.expneurol.2017.10.004","article-title":"The developing utility of zebrafish models of neurological and neuropsychiatric disorders: a critical review","volume":"299","author":"Fontana","year":"2018","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bios.2020.112315_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fphar.2018.00573","article-title":"Preclinical animal models for Dravet syndrome: seizure phenotypes, comorbidities and drug screening","volume":"9","author":"Griffin","year":"2018","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.bios.2020.112315_bib23","first-page":"669","article-title":"Clemizole and modulators of serotonin signalling suppress seizures in Dravet syndrome","volume":"140","author":"Griffin","year":"2017","journal-title":"Brain"},{"key":"10.1016\/j.bios.2020.112315_bib24","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1038\/nn.3934","article-title":"Animal models in epilepsy research: legacies and new directions","volume":"18","author":"Grone","year":"2015","journal-title":"Nat. Neurosci."},{"key":"10.1016\/j.bios.2020.112315_bib25","doi-asserted-by":"crossref","DOI":"10.1523\/ENEURO.0066-17.2017","article-title":"Behavioral comorbidities and drug treatments in a zebrafish scn1lab model of dravet syndrome","volume":"4","author":"Grone","year":"2017","journal-title":"eNeuro"},{"key":"10.1016\/j.bios.2020.112315_bib26","first-page":"63","article-title":"Linking genes to brain, behavior and neurological diseases: what can we learn from zebrafish? Genes","volume":"3","author":"Guo","year":"2004","journal-title":"Brain Behav"},{"key":"10.1016\/j.bios.2020.112315_bib27","doi-asserted-by":"crossref","first-page":"28248","DOI":"10.1038\/srep28248","article-title":"A novel long-term, multi-channel and non-invasive electrophysiology platform for zebrafish","volume":"6","author":"Hong","year":"2016","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bios.2020.112315_bib28","doi-asserted-by":"crossref","first-page":"498","DOI":"10.1038\/nature12111","article-title":"The zebrafish reference genome sequence and its relationship to the human genome","volume":"496","author":"Howe","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.bios.2020.112315_bib29","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.expneurol.2012.06.013","article-title":"A novel zebrafish model of hyperthermia-induced seizures reveals a role for TRPV4 channels and NMDA-type glutamate receptors","volume":"237","author":"Hunt","year":"2012","journal-title":"Exp. Neurol."},{"key":"10.1016\/j.bios.2020.112315_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.neuropharm.2020.107988","article-title":"Metabolism-based drug discovery in zebrafish: an emerging strategy to uncover new anti-seizure therapies","volume":"167","author":"Ibhazehiebo","year":"2020","journal-title":"Neuropharmacology"},{"key":"10.1016\/j.bios.2020.112315_bib31","doi-asserted-by":"crossref","first-page":"2210","DOI":"10.1093\/brain\/awu133","article-title":"On the nature of seizure dynamics","volume":"137","author":"Jirsa","year":"2014","journal-title":"Brain"},{"key":"10.1016\/j.bios.2020.112315_bib32","article-title":"Electrophysiological recording in the brain of intact adult zebrafish","volume":"1\u201311","author":"Johnston","year":"2013","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.bios.2020.112315_bib33","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/j.1528-1157.1997.tb01097.x","article-title":"Evolution of epilepsy and EEG findings in Angelman syndrome","volume":"38","author":"Laan","year":"1997","journal-title":"Epilepsia"},{"key":"10.1016\/j.bios.2020.112315_bib34","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.ejphar.2010.06.041","article-title":"Improvement of pentylenetetrazol-induced learning deficits by valproic acid in the adult zebrafish","volume":"643","author":"Lee","year":"2010","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.bios.2020.112315_bib35","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1093\/ilar.53.2.192","article-title":"Anesthesia and euthanasia in zebrafish","volume":"53","author":"Matthews","year":"2012","journal-title":"ILAR J."},{"key":"10.1016\/j.bios.2020.112315_bib36","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1471-2199-9-102","article-title":"Characterization of housekeeping genes in zebrafish: male-female differences and effects of tissue type, developmental stage and chemical treatment","volume":"9","author":"McCurley","year":"2008","journal-title":"BMC Mol. Biol."},{"key":"10.1016\/j.bios.2020.112315_bib37","article-title":"Microarray noninvasive neuronal seizure recordings from intact larval zebrafish","volume":"11","author":"Meyer","year":"2016","journal-title":"PloS One"},{"key":"10.1016\/j.bios.2020.112315_bib38","doi-asserted-by":"crossref","first-page":"884","DOI":"10.1016\/S0140-6736(14)60456-6","article-title":"Epilepsy: new advances","volume":"385","author":"Mosh\u00e9","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.bios.2020.112315_bib39","doi-asserted-by":"crossref","DOI":"10.1016\/j.pnpbp.2019.109770","article-title":"Zebrafish models: gaining insight into purinergic signaling and neurological disorders","volume":"98","author":"Nabinger","year":"2020","journal-title":"Prog. Neuro-Psychopharmacol. Biol. Psychiatry"},{"key":"10.1016\/j.bios.2020.112315_bib40","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1016\/0013-4694(90)90134-6","article-title":"Asymmetry in delta activity in patients with focal epilepsy","volume":"75","author":"Panet-Raymond","year":"1990","journal-title":"Electroencephalogr. Clin. Neurophysiol."},{"key":"10.1016\/j.bios.2020.112315_bib41","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.jneumeth.2011.06.001","article-title":"Recording the adult zebrafish cerebral field potential during pentylenetetrazole seizures","volume":"200","author":"Pineda","year":"2011","journal-title":"J. Neurosci. Methods"},{"key":"10.1016\/j.bios.2020.112315_bib42","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.eplepsyres.2011.12.016","article-title":"Non-resective surgery and radiosurgery for treatment of drug-resistant epilepsy","volume":"99","author":"Romanelli","year":"2012","journal-title":"Epilepsy Res."},{"key":"10.1016\/j.bios.2020.112315_bib43","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.brainresbull.2011.11.020","article-title":"Perspectives of zebrafish models of epilepsy: what, how and where next?","volume":"87","author":"Stewart","year":"2012","journal-title":"Brain Res. Bull."},{"key":"10.1016\/j.bios.2020.112315_bib44","doi-asserted-by":"crossref","first-page":"322","DOI":"10.1007\/s10072-003-0183-2","article-title":"Epileptic seizures in multiple sclerosis: clinical and EEG correlations","volume":"24","author":"Striano","year":"2003","journal-title":"Neurol. Sci."},{"key":"10.1016\/j.bios.2020.112315_bib45","doi-asserted-by":"crossref","first-page":"853","DOI":"10.1007\/s13238-015-0206-9","article-title":"Drug screening: zebrafish as a tool for studying epileptic-related chemical compounds","volume":"6","author":"Zhao","year":"2015","journal-title":"Protein Cell"}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566320303109?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566320303109?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T01:09:39Z","timestamp":1760663379000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566320303109"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9]]},"references-count":44,"alternative-id":["S0956566320303109"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2020.112315","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An EEG system to detect brain signals from multiple adult zebrafish","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2020.112315","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"112315"}}