{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T02:11:54Z","timestamp":1793239914373,"version":"4.5.0"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2021,12,1]],"date-time":"2021-12-01T00:00:00Z","timestamp":1638316800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2021,12]]},"DOI":"10.1016\/j.bios.2021.113601","type":"journal-article","created":{"date-parts":[[2021,9,6]],"date-time":"2021-09-06T01:41:56Z","timestamp":1630892516000},"page":"113601","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":84,"special_numbering":"C","title":["A novel electrochemiluminescence aptasensor based on copper-gold bimetallic nanoparticles and its applications"],"prefix":"10.1016","volume":"194","author":[{"given":"Jingcheng","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yaodong","family":"Xiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiansen","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qianqian","family":"Kong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongguo","family":"Zhai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rui","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengzhen","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xia","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yemin","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bios.2021.113601_bib1","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.jallcom.2019.03.279","volume":"791","author":"Cabello","year":"2019","journal-title":"J. Alloys Compd."},{"key":"10.1016\/j.bios.2021.113601_bib2","doi-asserted-by":"crossref","first-page":"1311","DOI":"10.1016\/S0956-5663(03)00084-8","volume":"18","author":"Cai","year":"2003","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2021.113601_bib3","doi-asserted-by":"crossref","first-page":"121476","DOI":"10.1016\/j.talanta.2020.121476","volume":"221","author":"Chen","year":"2021","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2021.113601_bib4","doi-asserted-by":"crossref","first-page":"127367","DOI":"10.1016\/j.snb.2019.127367","volume":"304","author":"Cheng","year":"2020","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.bios.2021.113601_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.jclepro.2020.122356","volume":"269","author":"Christopher","year":"2020","journal-title":"J. Clean. Prod."},{"key":"10.1016\/j.bios.2021.113601_bib6","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1016\/j.foodcont.2011.11.015","volume":"25","author":"Dong","year":"2012","journal-title":"Food Contr."},{"key":"10.1016\/j.bios.2021.113601_bib7","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.aca.2015.08.012","volume":"891","author":"Dou","year":"2015","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.bios.2021.113601_bib8","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1016\/j.snb.2019.02.057","volume":"287","author":"Fu","year":"2019","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.bios.2021.113601_bib9","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1016\/j.bios.2018.07.023","volume":"118","author":"Gai","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2021.113601_bib10","doi-asserted-by":"crossref","first-page":"123794","DOI":"10.1016\/j.jhazmat.2020.123794","volume":"401","author":"Guo","year":"2021","journal-title":"J. Hazard Mater."},{"key":"10.1016\/j.bios.2021.113601_bib11","doi-asserted-by":"crossref","first-page":"2683","DOI":"10.1021\/ac035276e","volume":"76","author":"Guo","year":"2004","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2021.113601_bib12","doi-asserted-by":"crossref","first-page":"111898","DOI":"10.1016\/j.bios.2019.111898","volume":"150","author":"He","year":"2020","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2021.113601_bib13","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.electacta.2017.04.139","volume":"241","author":"Hong","year":"2017","journal-title":"Electrochim. Acta"},{"key":"10.1016\/j.bios.2021.113601_bib14","doi-asserted-by":"crossref","first-page":"106835","DOI":"10.1016\/j.foodcont.2019.106835","volume":"108","author":"Huang","year":"2020","journal-title":"Food Contr."},{"key":"10.1016\/j.bios.2021.113601_bib15","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/S0003-2670(02)01014-0","volume":"474","author":"Huang","year":"2002","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.bios.2021.113601_bib16","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.materresbull.2015.12.026","volume":"79","author":"Iqbal","year":"2016","journal-title":"Mater. Res. Bull."},{"key":"10.1016\/j.bios.2021.113601_bib17","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1016\/j.talanta.2019.03.006","volume":"199","author":"Jian","year":"2019","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2021.113601_bib18","doi-asserted-by":"crossref","first-page":"13088","DOI":"10.1021\/acs.analchem.8b04334","volume":"90","author":"Jiang","year":"2018","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2021.113601_bib19","doi-asserted-by":"crossref","first-page":"10955","DOI":"10.1021\/jp111820b","volume":"115","author":"Le Gu\u00e9vel","year":"2011","journal-title":"J. Phys. Chem. C"},{"key":"10.1016\/j.bios.2021.113601_bib20","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.snb.2013.10.020","volume":"191","author":"Li","year":"2014","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.bios.2021.113601_bib21","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.trac.2019.01.008","volume":"113","author":"Li","year":"2019","journal-title":"TrAC Trends Anal. Chem. (Reference Ed.)"},{"key":"10.1016\/j.bios.2021.113601_bib22","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.aca.2019.12.012","volume":"1101","author":"Lin","year":"2020","journal-title":"Anal. Chim. Acta"},{"issue":"15","key":"10.1016\/j.bios.2021.113601_bib23","doi-asserted-by":"crossref","first-page":"B1562","DOI":"10.1149\/2.0801915jes","volume":"166","author":"Liu","year":"2019","journal-title":"J. Electrochem. Soc."},{"key":"10.1016\/j.bios.2021.113601_bib24","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1016\/j.bios.2019.01.006","volume":"130","author":"Liu","year":"2019","journal-title":"Biosens. Bioelectron."},{"issue":"2","key":"10.1016\/j.bios.2021.113601_bib31","doi-asserted-by":"crossref","first-page":"1886","DOI":"10.1021\/nn4063825","volume":"8","author":"Liu","year":"2014","journal-title":"ACS Nano"},{"key":"10.1016\/j.bios.2021.113601_bib25","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.snb.2018.02.101","volume":"263","author":"Luo","year":"2018","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.bios.2021.113601_bib26","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.talanta.2016.05.030","volume":"158","author":"Miao","year":"2016","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2021.113601_bib27","doi-asserted-by":"crossref","first-page":"111474","DOI":"10.1016\/j.bios.2019.111474","volume":"141","author":"Shahamirifard","year":"2019","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2021.113601_bib28","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1016\/j.bios.2018.05.009","volume":"114","author":"Shahamirifard","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2021.113601_bib29","doi-asserted-by":"crossref","first-page":"121267","DOI":"10.1016\/j.talanta.2020.121267","volume":"221","author":"Sharma","year":"2021","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2021.113601_bib30","doi-asserted-by":"crossref","first-page":"135905","DOI":"10.1016\/j.scitotenv.2019.135905","volume":"705","author":"Shi","year":"2020","journal-title":"Sci. Total Environ."},{"key":"10.1016\/j.bios.2021.113601_bib32","doi-asserted-by":"crossref","first-page":"112557","DOI":"10.1016\/j.bios.2020.112557","volume":"168","author":"Singh","year":"2020","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2021.113601_bib33","doi-asserted-by":"crossref","first-page":"126654","DOI":"10.1016\/j.snb.2019.126654","volume":"296","author":"Su","year":"2019","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.bios.2021.113601_bib34","doi-asserted-by":"crossref","first-page":"6136","DOI":"10.1021\/acs.analchem.0c00719","volume":"92","author":"Sun","year":"2020","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2021.113601_bib35","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.talanta.2015.08.023","volume":"146","author":"Tang","year":"2016","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2021.113601_bib36","doi-asserted-by":"crossref","first-page":"120094","DOI":"10.1016\/j.talanta.2019.06.094","volume":"205","author":"Wang","year":"2019","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2021.113601_bib37","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.bios.2017.10.042","volume":"101","author":"Wang","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2021.113601_bib38","doi-asserted-by":"crossref","first-page":"428","DOI":"10.1016\/j.snb.2019.01.113","volume":"287","author":"Xu","year":"2019","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.bios.2021.113601_bib39","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.trac.2018.04.014","volume":"105","author":"Yao","year":"2018","journal-title":"TrAC Trends Anal. Chem. (Reference Ed.)"},{"key":"10.1016\/j.bios.2021.113601_bib40","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1016\/j.aca.2008.12.050","volume":"635","author":"Yun","year":"2009","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.bios.2021.113601_bib41","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.bios.2013.12.020","volume":"55","author":"Zhang","year":"2014","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2021.113601_bib42","doi-asserted-by":"crossref","first-page":"111879","DOI":"10.1016\/j.bios.2019.111879","volume":"150","author":"Zhang","year":"2020","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2021.113601_bib43","doi-asserted-by":"crossref","first-page":"3911","DOI":"10.1021\/ac200480r","volume":"83","author":"Zhang","year":"2011","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2021.113601_bib44","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.trac.2018.06.017","volume":"106","author":"Zhao","year":"2018","journal-title":"TrAC Trends Anal. Chem. (Reference Ed.)"},{"key":"10.1016\/j.bios.2021.113601_bib45","doi-asserted-by":"crossref","first-page":"128985","DOI":"10.1016\/j.snb.2020.128985","volume":"326","author":"Zhao","year":"2021","journal-title":"Sensor. Actuator. B Chem."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566321006382?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566321006382?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T01:26:33Z","timestamp":1760664393000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566321006382"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12]]},"references-count":45,"alternative-id":["S0956566321006382"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2021.113601","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2021,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A novel electrochemiluminescence aptasensor based on copper-gold bimetallic nanoparticles and its applications","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2021.113601","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2021 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"113601"}}