{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T17:14:33Z","timestamp":1787764473268,"version":"build-2784847793"},"reference-count":47,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,9,1]],"date-time":"2022-09-01T00:00:00Z","timestamp":1661990400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["21707053"],"award-info":[{"award-number":["21707053"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2022,9]]},"DOI":"10.1016\/j.bios.2022.114393","type":"journal-article","created":{"date-parts":[[2022,5,18]],"date-time":"2022-05-18T21:02:02Z","timestamp":1652907722000},"page":"114393","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":43,"special_numbering":"C","title":["Rapid and sensitive detection of Ebola RNA in an unamplified sample based on CRISPR-Cas13a and DNA roller machine"],"prefix":"10.1016","volume":"211","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6141-3955","authenticated-orcid":false,"given":"Xiao-Min","family":"Hang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peng-Fei","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sen","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hui-Yi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kai-Ren","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bios.2022.114393_bib1","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1038\/nature24049","volume":"550","author":"Abudayyeh","year":"2017","journal-title":"Nature"},{"key":"10.1016\/j.bios.2022.114393_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.meegid.2020.104215","volume":"81","author":"Artika","year":"2020","journal-title":"Infect. Genet. Evol."},{"key":"10.1016\/j.bios.2022.114393_bib3","volume":"31","author":"Bruch","year":"2019","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bios.2022.114393_bib4","doi-asserted-by":"crossref","first-page":"459","DOI":"10.1016\/j.bios.2016.09.082","volume":"90","author":"Cao","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2022.114393_bib5","doi-asserted-by":"crossref","first-page":"383","DOI":"10.3389\/fpubh.2020.00383","volume":"8","author":"Chams","year":"2020","journal-title":"Front. Public Health"},{"key":"10.1016\/j.bios.2022.114393_bib6","volume":"120","author":"Chen","year":"2019","journal-title":"Trends Analyt. Chem."},{"key":"10.1016\/j.bios.2022.114393_bib7","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1126\/science.aar6245","volume":"360","author":"Chen","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.bios.2022.114393_bib8","author":"Chen","year":"2021","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.bios.2022.114393_bib9","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1126\/science.aat4982","volume":"360","author":"Chertow","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.bios.2022.114393_bib10","doi-asserted-by":"crossref","first-page":"13475","DOI":"10.1021\/acsnano.1c03975","volume":"15","author":"Choi","year":"2021","journal-title":"ACS Nano"},{"key":"10.1016\/j.bios.2022.114393_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-019-13993-7","volume":"11","author":"Ding","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bios.2022.114393_bib12","volume":"184","author":"Ding","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2022.114393_bib13","doi-asserted-by":"crossref","first-page":"489","DOI":"10.1016\/j.bios.2016.12.071","volume":"91","author":"Du","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2022.114393_bib14","doi-asserted-by":"crossref","first-page":"12433","DOI":"10.1021\/acs.analchem.7b03527","volume":"89","author":"Du","year":"2017","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2022.114393_bib15","doi-asserted-by":"crossref","first-page":"323","DOI":"10.1016\/j.cell.2020.12.001","volume":"184","author":"Fozouni","year":"2021","journal-title":"Cell"},{"key":"10.1016\/j.bios.2022.114393_bib16","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1126\/science.aaq0179","volume":"360","author":"Gootenberg","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.bios.2022.114393_bib17","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1126\/science.aam9321","volume":"356","author":"Gootenberg","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.bios.2022.114393_bib18","author":"He","year":"2022","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.bios.2022.114393_bib19","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/s41579-020-00459-7","volume":"19","author":"Hu","year":"2021","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.bios.2022.114393_bib20","doi-asserted-by":"crossref","first-page":"7430","DOI":"10.1021\/ja4023978","volume":"135","author":"Jiang","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bios.2022.114393_bib21","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1038\/nnano.2015.246","volume":"11","author":"Jung","year":"2016","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.bios.2022.114393_bib22","doi-asserted-by":"crossref","first-page":"2986","DOI":"10.1038\/s41596-019-0210-2","volume":"14","author":"Kellner","year":"2019","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.bios.2022.114393_bib23","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1038\/s41422-018-0022-x","volume":"28","author":"Li","year":"2018","journal-title":"Cell Res."},{"key":"10.1016\/j.bios.2022.114393_bib24","doi-asserted-by":"crossref","first-page":"5527","DOI":"10.1039\/C7CC02306E","volume":"53","author":"Li","year":"2017","journal-title":"Chem. Comm."},{"key":"10.1016\/j.bios.2022.114393_bib25","doi-asserted-by":"crossref","first-page":"730","DOI":"10.1016\/j.tibtech.2018.12.005","volume":"37","author":"Li","year":"2019","journal-title":"Trends Biotechnol."},{"key":"10.1016\/j.bios.2022.114393_bib26","doi-asserted-by":"crossref","first-page":"9077","DOI":"10.1002\/anie.201704147","volume":"56","author":"Liang","year":"2017","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.bios.2022.114393_bib27","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1016\/j.trac.2018.08.015","volume":"107","author":"Mason","year":"2018","journal-title":"Trends Analyt. Chem."},{"key":"10.1016\/j.bios.2022.114393_bib28","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1126\/science.aas8836","volume":"360","author":"Myhrvold","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.bios.2022.114393_bib29","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.bios.2018.02.040","volume":"108","author":"Na","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2022.114393_bib30","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2020.128053","volume":"314","author":"Pang","year":"2020","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.bios.2022.114393_bib31","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s41467-016-0009-6","volume":"8","author":"Peng","year":"2017","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bios.2022.114393_bib32","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1021\/acssensors.9b00239","volume":"4","author":"Qin","year":"2019","journal-title":"ACS Sens."},{"key":"10.1016\/j.bios.2022.114393_bib33","doi-asserted-by":"crossref","first-page":"281","DOI":"10.3389\/fneur.2019.00281","volume":"10","author":"Radmard","year":"2019","journal-title":"Front. Neurol."},{"key":"10.1016\/j.bios.2022.114393_bib34","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1038\/s42003-021-02001-8","volume":"4","author":"Shinoda","year":"2021","journal-title":"Commun. Biol."},{"key":"10.1016\/j.bios.2022.114393_bib35","doi-asserted-by":"crossref","first-page":"4363","DOI":"10.1021\/acs.analchem.7b00646","volume":"89","author":"Taskova","year":"2017","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2022.114393_bib36","doi-asserted-by":"crossref","first-page":"1167","DOI":"10.1021\/acsnano.0c08165","volume":"15","author":"Tian","year":"2020","journal-title":"ACS Nano"},{"key":"10.1016\/j.bios.2022.114393_bib37","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1021\/acsnano.5b05622","volume":"10","author":"Tsang","year":"2016","journal-title":"ACS Nano"},{"key":"10.1016\/j.bios.2022.114393_bib38","doi-asserted-by":"crossref","first-page":"9717","DOI":"10.1073\/pnas.86.24.9717","volume":"86","author":"Wang","year":"1989","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"key":"10.1016\/j.bios.2022.114393_bib39","doi-asserted-by":"crossref","first-page":"655","DOI":"10.1016\/j.snb.2016.01.036","volume":"227","author":"Wen","year":"2016","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.bios.2022.114393_bib40","volume":"274","author":"Wu","year":"2021","journal-title":"Biomaterials"},{"key":"10.1016\/j.bios.2022.114393_bib41","doi-asserted-by":"crossref","first-page":"47425","DOI":"10.1039\/C7RA09781F","volume":"7","author":"Xing","year":"2017","journal-title":"RSC Adv."},{"key":"10.1016\/j.bios.2022.114393_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2021.338523","volume":"1171","author":"Xu","year":"2021","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.bios.2022.114393_bib43","doi-asserted-by":"crossref","first-page":"4883","DOI":"10.1021\/acs.analchem.9b00728","volume":"91","author":"Xu","year":"2019","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2022.114393_bib44","doi-asserted-by":"crossref","first-page":"2324","DOI":"10.1021\/acsnano.5b07102","volume":"10","author":"Yang","year":"2016","journal-title":"ACS Nano"},{"key":"10.1016\/j.bios.2022.114393_bib45","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1038\/nnano.2015.259","volume":"11","author":"Yehl","year":"2016","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.bios.2022.114393_bib46","doi-asserted-by":"crossref","first-page":"5948","DOI":"10.1002\/anie.202012801","volume":"60","author":"Yu","year":"2021","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.bios.2022.114393_bib47","doi-asserted-by":"crossref","first-page":"4643","DOI":"10.1021\/acs.nanolett.1c00715","volume":"21","author":"Yue","year":"2021","journal-title":"Nano Lett."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095656632200433X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095656632200433X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T01:35:13Z","timestamp":1760664913000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S095656632200433X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9]]},"references-count":47,"alternative-id":["S095656632200433X"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2022.114393","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2022,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Rapid and sensitive detection of Ebola RNA in an unamplified sample based on CRISPR-Cas13a and DNA roller machine","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2022.114393","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"114393"}}