{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T06:12:35Z","timestamp":1789625555302,"version":"build-2803163510"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,4,1]],"date-time":"2023-04-01T00:00:00Z","timestamp":1680307200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002642","name":"Korea University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002642","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Korea Ministry of Science and ICT","doi-asserted-by":"publisher","award":["NRF-2020R1A2C2102262"],"award-info":[{"award-number":["NRF-2020R1A2C2102262"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Korea Ministry of Science and ICT","doi-asserted-by":"publisher","award":["NRF-2022R1A2C1091756"],"award-info":[{"award-number":["NRF-2022R1A2C1091756"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Korea Ministry of Science and ICT","doi-asserted-by":"publisher","award":["NRF-2022R1A6A3A03066467"],"award-info":[{"award-number":["NRF-2022R1A6A3A03066467"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Korea Ministry of Science and ICT","doi-asserted-by":"publisher","award":["NRF-2018M3C1B7020722"],"award-info":[{"award-number":["NRF-2018M3C1B7020722"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003621","name":"Ministry of Science, ICT and Future Planning","doi-asserted-by":"publisher","award":["2021M3E5E3080743"],"award-info":[{"award-number":["2021M3E5E3080743"]}],"id":[{"id":"10.13039\/501100003621","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003621","name":"Ministry of Science, ICT and Future Planning","doi-asserted-by":"publisher","award":["NRF-2022R1A6A3A13072828"],"award-info":[{"award-number":["NRF-2022R1A6A3A13072828"]}],"id":[{"id":"10.13039\/501100003621","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2023,4]]},"DOI":"10.1016\/j.bios.2023.115105","type":"journal-article","created":{"date-parts":[[2023,1,28]],"date-time":"2023-01-28T18:37:09Z","timestamp":1674931029000},"page":"115105","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":18,"special_numbering":"C","title":["Caco-2 cell-derived biomimetic electrochemical biosensor for cholera toxin detection"],"prefix":"10.1016","volume":"226","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4680-9406","authenticated-orcid":false,"given":"Yonghwan","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongtak","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Youngjun","family":"Seo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hyo Gi","family":"Jung","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jae Won","family":"Jang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dongsung","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5359-0890","authenticated-orcid":false,"given":"Insu","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3826-8208","authenticated-orcid":false,"given":"Jaeheung","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gyudo","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyo Seon","family":"Hwang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung-Hyun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sang Won","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7344-6060","authenticated-orcid":false,"given":"Jeong Hoon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dae Sung","family":"Yoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.bios.2023.115105_bib1","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0003832","volume":"9","author":"Ali","year":"2015","journal-title":"PLoS Neglected Trop. Dis."},{"key":"10.1016\/j.bios.2023.115105_bib2","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.bios.2015.06.069","volume":"74","author":"Archibald","year":"2015","journal-title":"Biosens. Bioelectron."},{"issue":"1","key":"10.1016\/j.bios.2023.115105_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/1475-2891-6-42","volume":"6","author":"Bouhnik","year":"2007","journal-title":"Nutr. J."},{"issue":"10","key":"10.1016\/j.bios.2023.115105_bib4","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1016\/j.biocel.2007.07.005","volume":"39","author":"Broeck","year":"2007","journal-title":"Int. J. Biochem. Cell Biol."},{"issue":"16","key":"10.1016\/j.bios.2023.115105_bib5","doi-asserted-by":"crossref","first-page":"7968","DOI":"10.1021\/acs.analchem.6b00801","volume":"88","author":"Bruzas","year":"2016","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2023.115105_bib6","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1146\/annurev.anchem.012809.102211","volume":"3","author":"Chang","year":"2010","journal-title":"Annu. Rev. Anal. Chem."},{"issue":"4","key":"10.1016\/j.bios.2023.115105_bib7","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1039\/C0LC00409J","volume":"11","author":"Chiriaco","year":"2011","journal-title":"Lab Chip"},{"issue":"6","key":"10.1016\/j.bios.2023.115105_bib8","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0009521","volume":"15","author":"Chowdhury","year":"2021","journal-title":"PLoS Neglected Trop. Dis."},{"issue":"1","key":"10.1016\/j.bios.2023.115105_bib9","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ab.2007.04.019","volume":"368","author":"Edwards","year":"2007","journal-title":"Anal. Biochem."},{"issue":"23","key":"10.1016\/j.bios.2023.115105_bib10","doi-asserted-by":"crossref","DOI":"10.1002\/adma.201706759","volume":"30","author":"Fang","year":"2018","journal-title":"Adv. Mater."},{"issue":"4","key":"10.1016\/j.bios.2023.115105_bib11","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1016\/S0968-4328(01)00026-9","volume":"33","author":"Fotiadis","year":"2002","journal-title":"Micron"},{"issue":"6","key":"10.1016\/j.bios.2023.115105_bib12","first-page":"532","volume":"6","author":"Gao","year":"2014","journal-title":"Wiley interdisciplinary reviews: nanomedicine and nanobiotechnology"},{"issue":"3","key":"10.1016\/j.bios.2023.115105_bib13","doi-asserted-by":"crossref","first-page":"3714","DOI":"10.1021\/acsnano.9b00911","volume":"13","author":"Gong","year":"2019","journal-title":"ACS Nano"},{"issue":"2","key":"10.1016\/j.bios.2023.115105_bib14","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1080\/09687680410001663267","volume":"21","author":"Haan","year":"2004","journal-title":"Mol. Membr. Biol."},{"issue":"7","key":"10.1016\/j.bios.2023.115105_bib15","doi-asserted-by":"crossref","first-page":"2520","DOI":"10.1073\/pnas.72.7.2520","volume":"72","author":"Holmgren","year":"1975","journal-title":"Proc. Natl. Acad. Sci. USA"},{"issue":"4","key":"10.1016\/j.bios.2023.115105_bib16","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1007\/s13534-021-00206-8","volume":"11","author":"Homayoonnia","year":"2021","journal-title":"Biomed Eng Lett"},{"key":"10.1016\/j.bios.2023.115105_bib17","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.bios.2017.12.002","volume":"102","author":"Kim","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2023.115105_bib18","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.bios.2019.04.007","volume":"135","author":"Kim","year":"2019","journal-title":"Biosens. Bioelectron."},{"issue":"6","key":"10.1016\/j.bios.2023.115105_bib19","doi-asserted-by":"crossref","first-page":"2125","DOI":"10.1039\/C9AN02421B","volume":"145","author":"Kim","year":"2020","journal-title":"Analyst"},{"key":"10.1016\/j.bios.2023.115105_bib20","volume":"190","author":"Kim","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2023.115105_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2021.113267","volume":"185","author":"Kim","year":"2021","journal-title":"Biosens. Bioelectron."},{"issue":"4","key":"10.1016\/j.bios.2023.115105_bib22","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1007\/s13534-021-00204-w","volume":"11","author":"Kim","year":"2021","journal-title":"Biomed Eng Lett"},{"issue":"11","key":"10.1016\/j.bios.2023.115105_bib23","doi-asserted-by":"crossref","first-page":"1557","DOI":"10.1007\/s00726-018-2630-7","volume":"50","author":"Kiss","year":"2018","journal-title":"Amino Acids"},{"key":"10.1016\/j.bios.2023.115105_bib24","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/j.bios.2014.05.017","volume":"61","author":"Kongsuphol","year":"2014","journal-title":"Biosens. Bioelectron."},{"issue":"3","key":"10.1016\/j.bios.2023.115105_bib25","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1016\/j.diagmicrobio.2009.07.009","volume":"65","author":"Koskela","year":"2009","journal-title":"Diagn. Microbiol. Infect. Dis."},{"issue":"20","key":"10.1016\/j.bios.2023.115105_bib26","volume":"8","author":"Lee","year":"2021","journal-title":"Adv. Sci."},{"issue":"1","key":"10.1016\/j.bios.2023.115105_bib27","first-page":"1","volume":"12","author":"Lee","year":"2021","journal-title":"Nat. Commun."},{"issue":"2","key":"10.1016\/j.bios.2023.115105_bib28","doi-asserted-by":"crossref","first-page":"2538","DOI":"10.1021\/acsami.2c14650","volume":"15","author":"Lee","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.bios.2023.115105_bib29","series-title":"Measurement Science and Technology","author":"Lee","year":"2022"},{"issue":"4","key":"10.1016\/j.bios.2023.115105_bib30","doi-asserted-by":"crossref","first-page":"510","DOI":"10.1128\/mr.47.4.510-550.1983","volume":"47","author":"Levine","year":"1983","journal-title":"Microbiol. Rev."},{"issue":"9","key":"10.1016\/j.bios.2023.115105_bib31","doi-asserted-by":"crossref","first-page":"1678","DOI":"10.1002\/cjoc.201090284","volume":"28","author":"Li","year":"2010","journal-title":"Chin. J. Chem."},{"key":"10.1016\/j.bios.2023.115105_bib32","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1016\/j.bios.2017.07.075","volume":"99","author":"Lim","year":"2018","journal-title":"Biosens. Bioelectron."},{"issue":"2","key":"10.1016\/j.bios.2023.115105_bib33","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1016\/0003-2697(80)90667-3","volume":"109","author":"Magnani","year":"1980","journal-title":"Anal. Biochem."},{"issue":"2","key":"10.1016\/j.bios.2023.115105_bib34","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1002\/1438-5171(200107)2:2<109::AID-SIMO109>3.0.CO;2-L","volume":"2","author":"Milhiet","year":"2001","journal-title":"Single Mol."},{"issue":"10","key":"10.1016\/j.bios.2023.115105_bib35","doi-asserted-by":"crossref","first-page":"1654","DOI":"10.1038\/nprot.2008.149","volume":"3","author":"Mingeot-Leclercq","year":"2008","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.bios.2023.115105_bib36","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2458-13-556","volume":"13","author":"Momtaz","year":"2013","journal-title":"BMC Publ. Health"},{"issue":"1","key":"10.1016\/j.bios.2023.115105_bib37","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1016\/j.bios.2005.12.007","volume":"22","author":"Ngundi","year":"2006","journal-title":"Biosens. Bioelectron."},{"issue":"11","key":"10.1016\/j.bios.2023.115105_bib38","doi-asserted-by":"crossref","first-page":"5762","DOI":"10.1021\/acsomega.9b03820","volume":"5","author":"Ozoemena","year":"2020","journal-title":"ACS Omega"},{"issue":"8","key":"10.1016\/j.bios.2023.115105_bib39","doi-asserted-by":"crossref","first-page":"1421","DOI":"10.1242\/jcs.01009","volume":"117","author":"Pang","year":"2004","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.bios.2023.115105_bib40","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.snb.2019.05.016","volume":"293","author":"Park","year":"2019","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.bios.2023.115105_bib41","doi-asserted-by":"crossref","first-page":"806","DOI":"10.1016\/j.bios.2018.11.053","volume":"126","author":"Russell","year":"2019","journal-title":"Biosens. Bioelectron."},{"issue":"2","key":"10.1016\/j.bios.2023.115105_bib42","first-page":"153","volume":"133","author":"S\u00e1nchez","year":"2011","journal-title":"Indian J. Med. Res."},{"issue":"9","key":"10.1016\/j.bios.2023.115105_bib43","doi-asserted-by":"crossref","first-page":"4233","DOI":"10.1021\/ac300242k","volume":"84","author":"Schmit","year":"2012","journal-title":"Anal. Chem."},{"issue":"4","key":"10.1016\/j.bios.2023.115105_bib44","doi-asserted-by":"crossref","first-page":"1356","DOI":"10.1021\/ac061462j","volume":"79","author":"Schofield","year":"2007","journal-title":"Anal. Chem."},{"issue":"2","key":"10.1016\/j.bios.2023.115105_bib45","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1002\/jso.2930520204","volume":"52","author":"Sloan","year":"1993","journal-title":"J. Surg. Oncol."},{"issue":"15","key":"10.1016\/j.bios.2023.115105_bib46","doi-asserted-by":"crossref","first-page":"6501","DOI":"10.1021\/la049554w","volume":"20","author":"Stine","year":"2004","journal-title":"Langmuir"},{"key":"10.1016\/j.bios.2023.115105_bib47","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.jelechem.2017.04.023","volume":"794","author":"Tammam","year":"2017","journal-title":"J. Electroanal. Chem."},{"issue":"5","key":"10.1016\/j.bios.2023.115105_bib48","doi-asserted-by":"crossref","first-page":"363","DOI":"10.1136\/sti.79.5.363","volume":"79","author":"Vickerman","year":"2003","journal-title":"Sex. Transm. Infect."},{"key":"10.1016\/j.bios.2023.115105_bib49","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.snb.2018.12.008","volume":"283","author":"Xu","year":"2019","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.bios.2023.115105_bib50","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1016\/j.bios.2015.03.048","volume":"70","author":"Yu","year":"2015","journal-title":"Biosens. Bioelectron."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566323000477?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566323000477?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T17:30:05Z","timestamp":1778779805000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566323000477"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4]]},"references-count":50,"alternative-id":["S0956566323000477"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2023.115105","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2023,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Caco-2 cell-derived biomimetic electrochemical biosensor for cholera toxin detection","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2023.115105","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"115105"}}