{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,19]],"date-time":"2026-10-19T19:57:17Z","timestamp":1792439837496,"version":"4.5.0"},"reference-count":62,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,2,1]],"date-time":"2024-02-01T00:00:00Z","timestamp":1706745600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,8]],"date-time":"2023-12-08T00:00:00Z","timestamp":1701993600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2024,2]]},"DOI":"10.1016\/j.bios.2023.115915","type":"journal-article","created":{"date-parts":[[2023,12,7]],"date-time":"2023-12-07T22:45:35Z","timestamp":1701989135000},"page":"115915","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":50,"special_numbering":"C","title":["Early-stage diagnosis of bladder cancer using surface-enhanced Raman spectroscopy combined with machine learning algorithms in a rat model"],"prefix":"10.1016","volume":"246","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4850-1886","authenticated-orcid":false,"given":"Sanghwa","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-0260-1258","authenticated-orcid":false,"given":"Miyeon","family":"Jue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9916-4931","authenticated-orcid":false,"given":"Kwanhee","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bjorn","family":"Paulson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9304-3346","authenticated-orcid":false,"given":"Jeongmin","family":"Oh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minju","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Ki","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bios.2023.115915_bib1","doi-asserted-by":"crossref","first-page":"96","DOI":"10.1016\/j.eururo.2016.06.010","volume":"71","author":"Antoni","year":"2017","journal-title":"Eur. Urol."},{"issue":"3","key":"10.1016\/j.bios.2023.115915_bib2","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1002\/cem.785","volume":"17","author":"Barker","year":"2003","journal-title":"J. Chemometr."},{"issue":"1","key":"10.1016\/j.bios.2023.115915_bib3","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1007\/s10103-013-1347-9","volume":"29","author":"Bhattacharjee","year":"2014","journal-title":"Laser Med. Sci."},{"issue":"21","key":"10.1016\/j.bios.2023.115915_bib4","doi-asserted-by":"crossref","first-page":"1603","DOI":"10.1093\/jnci\/87.21.1603","volume":"87","author":"Bochner","year":"1995","journal-title":"J. Natl. Cancer Inst."},{"issue":"27","key":"10.1016\/j.bios.2023.115915_bib5","doi-asserted-by":"crossref","first-page":"8265","DOI":"10.1007\/s00216-015-8697-z","volume":"407","author":"Bonifacio","year":"2015","journal-title":"Anal. Bioanal. Chem."},{"issue":"6","key":"10.1016\/j.bios.2023.115915_bib6","doi-asserted-by":"crossref","first-page":"1052","DOI":"10.1038\/bjc.2015.21","volume":"112","author":"Bryan","year":"2015","journal-title":"Br. J. Cancer"},{"issue":"4","key":"10.1016\/j.bios.2023.115915_bib7","doi-asserted-by":"crossref","first-page":"1324","DOI":"10.1021\/ac801665m","volume":"81","author":"Chan","year":"2009","journal-title":"Anal. Chem."},{"issue":"2","key":"10.1016\/j.bios.2023.115915_bib8","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1529\/biophysj.105.066761","volume":"90","author":"Chan","year":"2006","journal-title":"Biophys. J."},{"issue":"7","key":"10.1016\/j.bios.2023.115915_bib9","doi-asserted-by":"crossref","first-page":"3533","DOI":"10.1364\/BOE.10.003533","volume":"10","author":"Chen","year":"2019","journal-title":"Biomed. Opt Express"},{"key":"10.1016\/j.bios.2023.115915_bib10","doi-asserted-by":"crossref","first-page":"S70","DOI":"10.1038\/modpathol.2009.1","volume":"22","author":"Cheng","year":"2009","journal-title":"Mod. Pathol."},{"issue":"2","key":"10.1016\/j.bios.2023.115915_bib11","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1002\/jemt.20229","volume":"68","author":"Cheng","year":"2005","journal-title":"Microsc. Res. Tech."},{"key":"10.1016\/j.bios.2023.115915_bib12","volume":"240","author":"Cui","year":"2020","journal-title":"Spectoc. Acta Pt. A Mol. Biomol. Spectr."},{"issue":"12","key":"10.1016\/j.bios.2023.115915_bib13","doi-asserted-by":"crossref","first-page":"3271","DOI":"10.1007\/s00216-015-8610-9","volume":"407","author":"Del Mistro","year":"2015","journal-title":"Anal. Bioanal. Chem."},{"issue":"14","key":"10.1016\/j.bios.2023.115915_bib14","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1038\/s41388-017-0099-6","volume":"37","author":"Fantini","year":"2018","journal-title":"Oncogene"},{"issue":"8","key":"10.1016\/j.bios.2023.115915_bib15","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1016\/j.patrec.2005.10.010","volume":"27","author":"Fawcett","year":"2006","journal-title":"Pattern Recog. Lett."},{"key":"10.1016\/j.bios.2023.115915_bib17","volume":"247","author":"Hu","year":"2021","journal-title":"Spectoc. Acta Pt. A Mol. Biomol. Spectr."},{"issue":"6","key":"10.1016\/j.bios.2023.115915_bib18","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1002\/ijc.11500","volume":"107","author":"Huang","year":"2003","journal-title":"Int. J. Cancer"},{"issue":"8","key":"10.1016\/j.bios.2023.115915_bib19","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0237070","volume":"15","author":"Huttanus","year":"2020","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.bios.2023.115915_bib20","doi-asserted-by":"crossref","first-page":"358","DOI":"10.1016\/j.intimp.2010.11.029","volume":"11","author":"Ishizuka","year":"2011","journal-title":"Int. Immunopharmacol."},{"issue":"4","key":"10.1016\/j.bios.2023.115915_bib21","doi-asserted-by":"crossref","first-page":"1388","DOI":"10.1016\/S0022-5347(05)68306-1","volume":"162","author":"Johnson","year":"1999","journal-title":"J. Urol."},{"issue":"3","key":"10.1016\/j.bios.2023.115915_bib22","doi-asserted-by":"crossref","DOI":"10.3390\/nano9030447","volume":"9","author":"Jue","year":"2019","journal-title":"Nanomaterials"},{"issue":"10061","key":"10.1016\/j.bios.2023.115915_bib23","doi-asserted-by":"crossref","first-page":"2796","DOI":"10.1016\/S0140-6736(16)30512-8","volume":"388","author":"Kamat","year":"2016","journal-title":"Lancet"},{"issue":"1","key":"10.1016\/j.bios.2023.115915_bib24","doi-asserted-by":"crossref","DOI":"10.1186\/s12944-021-01481-1","volume":"20","author":"Ke","year":"2021","journal-title":"Lipids Health Dis."},{"key":"10.1016\/j.bios.2023.115915_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2020.105632","volume":"160","author":"Kim","year":"2021","journal-title":"Microchem. J."},{"issue":"6a","key":"10.1016\/j.bios.2023.115915_bib26","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1016\/j.urology.2005.07.062","volume":"66","author":"Kirkali","year":"2005","journal-title":"Urology"},{"key":"10.1016\/j.bios.2023.115915_bib27","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/bs.mcb.2020.10.020","volume":"163","author":"Korac-Prlic","year":"2021","journal-title":"Methods Cell Biol."},{"key":"10.1016\/j.bios.2023.115915_bib29","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/j.saa.2018.06.045","volume":"204","author":"Lee","year":"2018","journal-title":"Spectoc. Acta Pt. A Mol. Biomol. Spectr."},{"key":"10.1016\/j.bios.2023.115915_bib30","doi-asserted-by":"crossref","first-page":"8121","DOI":"10.2147\/IJN.S272500","volume":"15","author":"Lee","year":"2020","journal-title":"Int. J. Nanomed."},{"issue":"2","key":"10.1016\/j.bios.2023.115915_bib31","volume":"9","author":"Lee","year":"2019","journal-title":"Nanomaterials"},{"issue":"8","key":"10.1016\/j.bios.2023.115915_bib32","volume":"12","author":"Lee","year":"2022","journal-title":"Biosensors Basel"},{"issue":"50","key":"10.1016\/j.bios.2023.115915_bib33","doi-asserted-by":"crossref","first-page":"17477","DOI":"10.1021\/acs.analchem.2c03634","volume":"94","author":"Lee","year":"2022","journal-title":"Anal. Chem."},{"issue":"1","key":"10.1016\/j.bios.2023.115915_bib34","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1007\/s13206-022-00045-4","volume":"16","author":"Lee","year":"2022","journal-title":"BioChip J"},{"key":"10.1016\/j.bios.2023.115915_bib35","volume":"5","author":"Li","year":"2015","journal-title":"Sci. Rep."},{"issue":"12","key":"10.1016\/j.bios.2023.115915_bib36","doi-asserted-by":"crossref","first-page":"7109","DOI":"10.1364\/BOE.406097","volume":"11","author":"Lin","year":"2020","journal-title":"Biomed. Opt Express"},{"key":"10.1016\/j.bios.2023.115915_bib37","volume":"2016","author":"Liu","year":"2016","journal-title":"J. Spectrosc."},{"issue":"2","key":"10.1016\/j.bios.2023.115915_bib38","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1159\/000518877","volume":"106","author":"Liu","year":"2022","journal-title":"Urol. Int."},{"issue":"25","key":"10.1016\/j.bios.2023.115915_bib39","doi-asserted-by":"crossref","first-page":"8743","DOI":"10.1021\/la990382q","volume":"15","author":"Luo","year":"1999","journal-title":"Langmuir"},{"key":"10.1016\/j.bios.2023.115915_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2019.115796","volume":"124","author":"Lussier","year":"2020","journal-title":"Trac-Trends Anal. Chem."},{"issue":"3","key":"10.1016\/j.bios.2023.115915_bib41","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1002\/bip.20398","volume":"81","author":"Malini","year":"2006","journal-title":"Biopolymers"},{"issue":"4","key":"10.1016\/j.bios.2023.115915_bib42","volume":"9","author":"Moisoiu","year":"2019","journal-title":"Appl. Sci.-Basel"},{"issue":"1","key":"10.1016\/j.bios.2023.115915_bib43","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1017\/S0266462310001364","volume":"27","author":"Mowatt","year":"2011","journal-title":"Int. J. Technol. Assess. Health Care"},{"issue":"7","key":"10.1016\/j.bios.2023.115915_bib44","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1002\/1097-0142(19840401)53:7<1555::AID-CNCR2820530723>3.0.CO;2-G","volume":"53","author":"Murphy","year":"1984","journal-title":"Cancer"},{"key":"10.1016\/j.bios.2023.115915_bib45","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/j.pdpdt.2015.07.174","volume":"13","author":"Nakai","year":"2016","journal-title":"Photodiagn. Photodyn. Ther."},{"issue":"12","key":"10.1016\/j.bios.2023.115915_bib46","doi-asserted-by":"crossref","first-page":"2450","DOI":"10.1039\/c1an15104e","volume":"136","author":"Nawaz","year":"2011","journal-title":"Analyst"},{"issue":"4","key":"10.1016\/j.bios.2023.115915_bib47","doi-asserted-by":"crossref","DOI":"10.3390\/ijms20040821","volume":"20","author":"Oeyen","year":"2019","journal-title":"Int. J. Mol. Sci."},{"issue":"11","key":"10.1016\/j.bios.2023.115915_bib48","doi-asserted-by":"crossref","first-page":"732","DOI":"10.1038\/nrc.2016.89","volume":"16","author":"Rohrig","year":"2016","journal-title":"Nat. Rev. Cancer"},{"issue":"1","key":"10.1016\/j.bios.2023.115915_bib49","volume":"8","author":"Saginala","year":"2020","journal-title":"Med. Sci."},{"issue":"1","key":"10.1016\/j.bios.2023.115915_bib50","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.eururo.2010.10.027","volume":"59","author":"Shapiro","year":"2011","journal-title":"Eur. Urol."},{"issue":"5","key":"10.1016\/j.bios.2023.115915_bib51","doi-asserted-by":"crossref","DOI":"10.1038\/ncb2956","volume":"16","author":"Shin","year":"2014","journal-title":"Nat. Cell Biol."},{"issue":"4","key":"10.1016\/j.bios.2023.115915_bib52","doi-asserted-by":"crossref","first-page":"521","DOI":"10.1016\/j.ccell.2014.09.001","volume":"26","author":"Shin","year":"2014","journal-title":"Cancer Cell"},{"issue":"1","key":"10.1016\/j.bios.2023.115915_bib53","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.cmet.2019.11.010","volume":"31","author":"Snaebjornsson","year":"2020","journal-title":"Cell Metab"},{"issue":"7","key":"10.1016\/j.bios.2023.115915_bib54","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1002\/jrs.882","volume":"33","author":"Stone","year":"2002","journal-title":"J. Raman Spectrosc."},{"key":"10.1016\/j.bios.2023.115915_bib55","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1039\/b304992b","volume":"126","author":"Stone","year":"2004","journal-title":"Faraday Discuss"},{"issue":"1","key":"10.1016\/j.bios.2023.115915_bib56","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1080\/05704928.2014.923902","volume":"50","author":"Talari","year":"2015","journal-title":"Appl. Spectrosc. Rev."},{"key":"10.1016\/j.bios.2023.115915_bib57","doi-asserted-by":"crossref","DOI":"10.1186\/s12944-019-0959-x","volume":"18","author":"Tan","year":"2019","journal-title":"Lipids Health Dis."},{"issue":"14","key":"10.1016\/j.bios.2023.115915_bib58","doi-asserted-by":"crossref","first-page":"9676","DOI":"10.1039\/C7CP90063E","volume":"19","author":"van Wilderen","year":"2017","journal-title":"Phys. Chem. Chem. Phys."},{"issue":"2","key":"10.1016\/j.bios.2023.115915_bib59","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1002\/jrs.2677","volume":"42","author":"Wang","year":"2011","journal-title":"J. Raman Spectrosc."},{"issue":"8","key":"10.1016\/j.bios.2023.115915_bib60","doi-asserted-by":"crossref","first-page":"2475","DOI":"10.1016\/j.nano.2016.07.014","volume":"12","author":"Xiao","year":"2016","journal-title":"Nanomed. Nanotechnol. Biol. Med."},{"issue":"3","key":"10.1016\/j.bios.2023.115915_bib61","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1021\/acssensors.9b02377","volume":"5","author":"Zhang","year":"2020","journal-title":"ACS Sens."},{"issue":"3","key":"10.1016\/j.bios.2023.115915_bib62","volume":"28","author":"Zhang","year":"2018","journal-title":"Laser Phys."},{"issue":"8","key":"10.1016\/j.bios.2023.115915_bib63","doi-asserted-by":"crossref","first-page":"4204","DOI":"10.1364\/BOE.465295","volume":"13","author":"Zhu","year":"2022","journal-title":"Biomed. Opt Express"},{"issue":"6","key":"10.1016\/j.bios.2023.115915_bib64","doi-asserted-by":"crossref","DOI":"10.1088\/1612-2011\/13\/6\/065604","volume":"13","author":"Zou","year":"2016","journal-title":"Laser Phys. Lett."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566323008576?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566323008576?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T01:53:17Z","timestamp":1760665997000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566323008576"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2]]},"references-count":62,"alternative-id":["S0956566323008576"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2023.115915","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Early-stage diagnosis of bladder cancer using surface-enhanced Raman spectroscopy combined with machine learning algorithms in a rat model","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2023.115915","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"115915"}}