{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,13]],"date-time":"2026-06-13T18:38:41Z","timestamp":1781375921163,"version":"3.54.1"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.bios.2024.116300","type":"journal-article","created":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T15:24:58Z","timestamp":1713799498000},"page":"116300","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"special_numbering":"C","title":["Culture-free detection of \u03b2-lactamase-Producing bacteria in urinary tract infections using a paper sensor"],"prefix":"10.1016","volume":"257","author":[{"given":"Guangming","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenshuai","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siya","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jia","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinsheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hua","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4153-9822","authenticated-orcid":false,"given":"Dingbin","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongmei","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"10","key":"10.1016\/j.bios.2024.116300_bib1","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1016\/j.cmi.2022.05.016","article-title":"Antibiotic management of urinary tract infections in the post-antibiotic era: a narrative review highlighting diagnostic and antimicrobial stewardship","volume":"29","author":"Abbott","year":"2023","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.bios.2024.116300_bib2","doi-asserted-by":"crossref","first-page":"115131","DOI":"10.1016\/j.bios.2023.115131","article-title":"Recent Advances in the development of enzymatic paper-based microfluidic biosensors","volume":"226","author":"Aghababaie","year":"2023","journal-title":"Biosens. Bioelectron."},{"issue":"16","key":"10.1016\/j.bios.2024.116300_bib3","doi-asserted-by":"crossref","first-page":"3806","DOI":"10.1039\/D3AN00679D","article-title":"Identification of bacteria in mixed infection from urinary tract of patient's samples using Raman analysis of dried droplets","volume":"148","author":"Aubrechtov\u00e1","year":"2023","journal-title":"Analyst"},{"issue":"10","key":"10.1016\/j.bios.2024.116300_bib4","doi-asserted-by":"crossref","first-page":"1213","DOI":"10.3390\/pathogens12101213","article-title":"New insights into the pathogenesis and treatment of urinary tract infections","volume":"12","author":"Biondo","year":"2023","journal-title":"Pathogens"},{"key":"10.1016\/j.bios.2024.116300_bib5","doi-asserted-by":"crossref","first-page":"103227","DOI":"10.1016\/j.iccn.2022.103227","article-title":"Healthcare-associated infections in adult intensive care unit patients: changes in epidemiology, diagnosis, prevention and contributions of new technologies","volume":"70","author":"Blot","year":"2022","journal-title":"Intensive Crit. Care Nurs."},{"issue":"8","key":"10.1016\/j.bios.2024.116300_bib6","doi-asserted-by":"crossref","first-page":"1290","DOI":"10.1093\/cid\/cix893","article-title":"Carbapenemase-producing organisms: a global scourge","volume":"66","author":"Bonomo","year":"2018","journal-title":"Clin. Infect. Dis."},{"issue":"4","key":"10.1016\/j.bios.2024.116300_bib7","first-page":"857","article-title":"Urinary tract infections: 2021 update","volume":"35","author":"Chenoweth","year":"2021","journal-title":"Infect. Dis. Clin."},{"issue":"12","key":"10.1016\/j.bios.2024.116300_bib8","doi-asserted-by":"crossref","first-page":"5559","DOI":"10.3390\/s23125559","article-title":"Smartphone-Enabled colorimetry","volume":"23","author":"Ciaccheri","year":"2023","journal-title":"Sensors"},{"key":"10.1016\/j.bios.2024.116300_bib9","doi-asserted-by":"crossref","first-page":"560622","DOI":"10.3389\/fcimb.2021.560622","article-title":"Escherichia coliClonal relationship and resistance profiles among ESBL-producing","volume":"11","author":"Dolatyar","year":"2021","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"12","key":"10.1016\/j.bios.2024.116300_bib10","doi-asserted-by":"crossref","first-page":"1689","DOI":"10.3390\/antibiotics12121689","article-title":"Evaluation of the diagnosis and antibiotic prescription pattern in patients hospitalized with urinary tract infections: single-center study from a university-affiliated hospital","volume":"12","author":"F\u00e9s\u00fcs","year":"2023","journal-title":"Antibiotics"},{"key":"10.1016\/j.bios.2024.116300_bib11","doi-asserted-by":"crossref","first-page":"125274","DOI":"10.1016\/j.talanta.2023.125274","article-title":"Genosensor on-chip paper for point of care detection: a review of biomedical analysis and food safety application","volume":"268","author":"Hilda","year":"2024","journal-title":"Talanta"},{"issue":"6","key":"10.1016\/j.bios.2024.116300_bib12","doi-asserted-by":"crossref","first-page":"2834","DOI":"10.1039\/D3NR05456J","article-title":"Recent progress in biosensor regeneration techniques","volume":"16","author":"Jia","year":"2024","journal-title":"Nanoscale"},{"issue":"2","key":"10.1016\/j.bios.2024.116300_bib13","doi-asserted-by":"crossref","first-page":"61","DOI":"10.3390\/antibiotics9020061","article-title":"Carbapenem-sparing strategies for ESBL producers: when and how","volume":"9","author":"Karaiskos","year":"2020","journal-title":"Antibiotics"},{"issue":"47","key":"10.1016\/j.bios.2024.116300_bib14","doi-asserted-by":"crossref","first-page":"4120","DOI":"10.1126\/sciadv.abq4120","article-title":"A sublingual nanofiber vaccine to prevent urinary tract infections","volume":"8","author":"Kelly","year":"2022","journal-title":"Sci. Adv."},{"issue":"8","key":"10.1016\/j.bios.2024.116300_bib15","doi-asserted-by":"crossref","first-page":"e2225730","DOI":"10.1001\/jamanetworkopen.2022.25730","article-title":"Antibiotic prescribing patterns and guideline concordance for uncomplicated urinary tract infections among adult women in the US military health system","volume":"5","author":"Kikuchi","year":"2022","journal-title":"JAMA Netw. Open"},{"issue":"1","key":"10.1016\/j.bios.2024.116300_bib16","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1021\/jacsau.2c00607","article-title":"Achieving ultrasensitive chromogenic probes for rapid, direct detection of carbapenemase-producing bacteria in sputum","volume":"3","author":"Li","year":"2023","journal-title":"JACS Au"},{"issue":"1","key":"10.1016\/j.bios.2024.116300_bib17","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1038\/s41467-024-44984-y","article-title":"Rapid and visual identification of \u03b2-lactamase subtypes for precision antibiotic therapy","volume":"15","author":"Li","year":"2024","journal-title":"Nat. Commun."},{"issue":"10","key":"10.1016\/j.bios.2024.116300_bib18","doi-asserted-by":"crossref","first-page":"2817","DOI":"10.3390\/jcm11102817","article-title":"Global and regional burden of bacterial antimicrobial resistance in urinary tract infections in 2019","volume":"11","author":"Li","year":"2022","journal-title":"J. Clin. Med."},{"issue":"24","key":"10.1016\/j.bios.2024.116300_bib19","doi-asserted-by":"crossref","first-page":"8007","DOI":"10.1007\/s00253-022-12272-8","article-title":"Cephalosporins as key lead generation beta-lactam antibiotics","volume":"106","author":"Lin","year":"2022","journal-title":"Appl. Microbiol. Biotechnol."},{"issue":"15","key":"10.1016\/j.bios.2024.116300_bib20","doi-asserted-by":"crossref","first-page":"3328","DOI":"10.1039\/D3LC00038A","article-title":"Printable biosensors towards next-generation point-of-care testing: paper substrate as an example","volume":"23","author":"Liu","year":"2023","journal-title":"Lab Chip"},{"issue":"1","key":"10.1016\/j.bios.2024.116300_bib21","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1186\/s13054-020-03102-2","article-title":"Usefulness of point-of-care multiplex PCR to rapidly identify pathogens responsible for ventilator-associated pneumonia and their resistance to antibiotics: an observational study","volume":"24","author":"Luyt","year":"2020","journal-title":"Crit. Care"},{"issue":"18","key":"10.1016\/j.bios.2024.116300_bib22","doi-asserted-by":"crossref","first-page":"6886","DOI":"10.1021\/jacs.1c00462","article-title":"Rapid broad spectrum detection of carbapenemases with a dual fluorogenic-colorimetric probe","volume":"143","author":"Ma","year":"2021","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bios.2024.116300_bib23","doi-asserted-by":"crossref","first-page":"115384","DOI":"10.1016\/j.bios.2023.115384","article-title":"Paper-based bipolar electrode electrochemiluminescence sensors for point-of-care testing","volume":"235","author":"Ma","year":"2023","journal-title":"Biosens. Bioelectron."},{"issue":"16","key":"10.1016\/j.bios.2024.116300_bib24","doi-asserted-by":"crossref","first-page":"4468","DOI":"10.1002\/anie.201612495","article-title":"Detection of carbapenemase-producing organisms with a carbapenem-based fluorogenic probe","volume":"56","author":"Mao","year":"2017","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.bios.2024.116300_bib25","doi-asserted-by":"crossref","first-page":"112649","DOI":"10.1016\/j.bios.2020.112649","article-title":"Paper-based microfluidic aptasensors","volume":"170","author":"Ming","year":"2020","journal-title":"Biosens. Bioelectron."},{"issue":"12","key":"10.1016\/j.bios.2024.116300_bib26","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.3390\/antibiotics11121740","article-title":"Multidrug-resistant enterobacterales in community-acquired urinary tract infections in Djibouti, republic of Djibouti","volume":"11","author":"Mohamed","year":"2022","journal-title":"Antibiotics"},{"issue":"10","key":"10.1016\/j.bios.2024.116300_bib27","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.3390\/microorganisms8101555","article-title":"Clinical relevance of antibiotic susceptibility profiles for screening gram-negative microorganisms resistant to beta-lactam antibiotics","volume":"8","author":"Montiel","year":"2020","journal-title":"Microorganisms"},{"issue":"1","key":"10.1016\/j.bios.2024.116300_bib28","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1186\/s13073-017-0461-x","article-title":"Next-generation sequencing to monitor the spread of antimicrobial resistance","volume":"9","author":"Otto","year":"2017","journal-title":"Genome Med."},{"issue":"7","key":"10.1016\/j.bios.2024.116300_bib29","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/j.chom.2023.06.011","article-title":"Multi-arming ourselves against drug-resistant bacteria","volume":"31","author":"Raherisoanjato","year":"2023","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.bios.2024.116300_bib30","doi-asserted-by":"crossref","first-page":"1281155","DOI":"10.3389\/fcimb.2023.1281155","article-title":"Rapid detection of antimicrobial resistance in methicillin-resistant Staphylococcus aureus using MALDI-TOF mass spectrometry","volume":"13","author":"Rensner","year":"2023","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"1","key":"10.1016\/j.bios.2024.116300_bib31","doi-asserted-by":"crossref","first-page":"456","DOI":"10.3390\/ijms22010456","article-title":"Emerging options for the diagnosis of bacterial infections and the characterization of antimicrobial resistance","volume":"22","author":"Rentschler","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"5","key":"10.1016\/j.bios.2024.116300_bib32","doi-asserted-by":"crossref","first-page":"738","DOI":"10.1093\/cid\/cix417","article-title":"Whole-genome sequencing accurately identifies resistance to extended-spectrum \u03b2-lactams for major gram-negative bacterial pathogens","volume":"65","author":"Shelburne","year":"2017","journal-title":"Clin. Infect. Dis."},{"issue":"6","key":"10.1016\/j.bios.2024.116300_bib33","doi-asserted-by":"crossref","first-page":"1407","DOI":"10.1007\/s00216-024-05135-w","article-title":"Wearable biosensors for human sweat glucose detection based on carbon black nanoparticles","volume":"416","author":"Tang","year":"2024","journal-title":"Anal. Bioanal. Chem."},{"issue":"24","key":"10.1016\/j.bios.2024.116300_bib34","doi-asserted-by":"crossref","first-page":"2955","DOI":"10.1039\/D3AY00613A","article-title":"A simple approach to develop a paper-based biosensor for real-time uric acid detection","volume":"15","author":"Verma","year":"2023","journal-title":"Anal. Methods"},{"issue":"4","key":"10.1016\/j.bios.2024.116300_bib35","doi-asserted-by":"crossref","first-page":"1702671","DOI":"10.1002\/smll.201702671","article-title":"Nanomotion detection method for testing antibiotic resistance and susceptibility of slow-growing bacteria","volume":"14","author":"Villalba","year":"2018","journal-title":"Small"},{"key":"10.1016\/j.bios.2024.116300_bib36","doi-asserted-by":"crossref","first-page":"101092","DOI":"10.1016\/j.nantod.2021.101092","article-title":"Point-of-care diagnostics for infectious diseases: from methods to devices","volume":"37","author":"Wang","year":"2021","journal-title":"Nano Today"},{"issue":"36","key":"10.1016\/j.bios.2024.116300_bib37","doi-asserted-by":"crossref","first-page":"13375","DOI":"10.1021\/acs.est.3c04001","article-title":"Metabolite-mediated bacterial antibiotic resistance revealed by surface-enhanced Raman spectroscopy","volume":"57","author":"Wang","year":"2023","journal-title":"Environ. Sci. Technol."},{"key":"10.1016\/j.bios.2024.116300_bib38","doi-asserted-by":"crossref","first-page":"114509","DOI":"10.1016\/j.bios.2022.114509","article-title":"Progress in smartphone-enabled aptasensors","volume":"215","author":"Zahra","year":"2022","journal-title":"Biosens. Bioelectron."},{"issue":"1","key":"10.1016\/j.bios.2024.116300_bib39","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1021\/acssensors.3c02144","article-title":"Metabolism-triggered plasmonic nanosensor for bacterial detection and antimicrobial susceptibility testing of clinical isolates","volume":"9","author":"Zhang","year":"2024","journal-title":"ACS Sens."},{"issue":"52","key":"10.1016\/j.bios.2024.116300_bib40","doi-asserted-by":"crossref","first-page":"17120","DOI":"10.1002\/anie.201810834","article-title":"Label-free visualization of carbapenemase activity in living bacteria","volume":"57","author":"Zhang","year":"2018","journal-title":"Angew. Chem. Int. Ed."},{"issue":"6","key":"10.1016\/j.bios.2024.116300_bib41","doi-asserted-by":"crossref","first-page":"847","DOI":"10.1016\/S1473-3099(20)30596-X","article-title":"Appropriateness of antibiotic prescriptions in ambulatory care in China: a nationwide descriptive database study","volume":"21","author":"Zhao","year":"2021","journal-title":"Lancet Infect. Dis."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566324003051?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566324003051?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T23:56:14Z","timestamp":1719878174000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566324003051"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":41,"alternative-id":["S0956566324003051"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2024.116300","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Culture-free detection of \u03b2-lactamase-Producing bacteria in urinary tract infections using a paper sensor","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2024.116300","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"116300"}}