{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T23:55:39Z","timestamp":1793922939730,"version":"4.8.0"},"reference-count":42,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22077069"],"award-info":[{"award-number":["22077069"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006606","name":"Natural Science Foundation of Tianjin Municipality","doi-asserted-by":"publisher","award":["21JCYBJC00310"],"award-info":[{"award-number":["21JCYBJC00310"]}],"id":[{"id":"10.13039\/501100006606","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2020YFA0907300"],"award-info":[{"award-number":["2020YFA0907300"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.bios.2024.116313","type":"journal-article","created":{"date-parts":[[2024,4,24]],"date-time":"2024-04-24T15:41:27Z","timestamp":1713973287000},"page":"116313","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":33,"special_numbering":"C","title":["Development of a CRISPR\/Cas12a-mediated aptasensor for Mpox virus antigen detection"],"prefix":"10.1016","volume":"257","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2738-5006","authenticated-orcid":false,"given":"Cong","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qirui","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuantong","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zheng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaxuan","family":"He","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Feng","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Ding","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaofeng","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liyun","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.bios.2024.116313_bib1","doi-asserted-by":"crossref","DOI":"10.1002\/jmv.28701","volume":"95","author":"Aden","year":"2023","journal-title":"J. Med. Virol."},{"issue":"1","key":"10.1016\/j.bios.2024.116313_bib2","doi-asserted-by":"crossref","first-page":"198","DOI":"10.1021\/acs.analchem.0c04364","volume":"93","author":"Bezerra","year":"2021","journal-title":"Anal. Chem."},{"issue":"13","key":"10.1016\/j.bios.2024.116313_bib3","doi-asserted-by":"crossref","first-page":"5382","DOI":"10.1021\/acs.analchem.2c00069","volume":"94","author":"Chen","year":"2022","journal-title":"Anal. Chem."},{"issue":"6387","key":"10.1016\/j.bios.2024.116313_bib4","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1126\/science.aar6245","volume":"360","author":"Chen","year":"2018","journal-title":"Science"},{"issue":"6","key":"10.1016\/j.bios.2024.116313_bib5","doi-asserted-by":"crossref","first-page":"1615","DOI":"10.1021\/acssensors.0c00081","volume":"5","author":"Chen","year":"2020","journal-title":"ACS Sens."},{"issue":"6","key":"10.1016\/j.bios.2024.116313_bib6","volume":"215","author":"Cheng","year":"2022","journal-title":"Biosens. Bioelectron."},{"issue":"39","key":"10.1016\/j.bios.2024.116313_bib7","doi-asserted-by":"crossref","first-page":"14651","DOI":"10.1021\/acs.analchem.3c02477","volume":"95","author":"Ding","year":"2023","journal-title":"Anal. Chem."},{"issue":"1","key":"10.1016\/j.bios.2024.116313_bib8","first-page":"7537","volume":"21","author":"Feng","year":"2023","journal-title":"BMC Med."},{"issue":"5","key":"10.1016\/j.bios.2024.116313_bib9","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1038\/nbt0502-473","volume":"20","author":"Fredriksson","year":"2002","journal-title":"Nat. Biotechnol."},{"issue":"1","key":"10.1016\/j.bios.2024.116313_bib10","doi-asserted-by":"crossref","first-page":"7537","DOI":"10.1186\/s12985-023-02085-0","volume":"20","author":"Gao","year":"2023","journal-title":"Virol. J."},{"issue":"19","key":"10.1016\/j.bios.2024.116313_bib11","doi-asserted-by":"crossref","first-page":"1783","DOI":"10.1056\/NEJMra2208860","volume":"387","author":"Gessain","year":"2022","journal-title":"N. Engl. J. Med."},{"issue":"11","key":"10.1016\/j.bios.2024.116313_bib12","doi-asserted-by":"crossref","first-page":"1298","DOI":"10.1002\/asia.202100242","volume":"16","author":"Han","year":"2021","journal-title":"Chem. Asian J."},{"issue":"23","key":"10.1016\/j.bios.2024.116313_bib13","volume":"200","author":"Han","year":"2022","journal-title":"Biosens. Bioelectron."},{"issue":"23","key":"10.1016\/j.bios.2024.116313_bib14","volume":"380","author":"Han","year":"2023","journal-title":"Sensor. Actuator. B Chem."},{"issue":"5","key":"10.1016\/j.bios.2024.116313_bib15","first-page":"7537","volume":"21","author":"He","year":"2023","journal-title":"Drugs"},{"issue":"18","key":"10.1016\/j.bios.2024.116313_bib16","doi-asserted-by":"crossref","first-page":"12596","DOI":"10.1021\/acs.analchem.0c02619","volume":"92","author":"Huertas","year":"2020","journal-title":"Anal. Chem."},{"issue":"8","key":"10.1016\/j.bios.2024.116313_bib17","doi-asserted-by":"crossref","first-page":"3093","DOI":"10.1021\/acssensors.1c01222","volume":"6","author":"Idili","year":"2021","journal-title":"ACS Sens."},{"issue":"17","key":"10.1016\/j.bios.2024.116313_bib18","volume":"194","author":"Kim","year":"2021","journal-title":"Biosens. Bioelectron."},{"issue":"1","key":"10.1016\/j.bios.2024.116313_bib19","doi-asserted-by":"crossref","first-page":"3672","DOI":"10.1038\/s41467-019-11648-1","volume":"10","author":"Liang","year":"2019","journal-title":"Nat. Commun."},{"issue":"44","key":"10.1016\/j.bios.2024.116313_bib20","doi-asserted-by":"crossref","first-page":"12157","DOI":"10.1039\/D0SC03920A","volume":"11","author":"Liu","year":"2020","journal-title":"Chem. Sci."},{"issue":"11","key":"10.1016\/j.bios.2024.116313_bib21","doi-asserted-by":"crossref","first-page":"4736","DOI":"10.1021\/acs.jafc.2c07965","volume":"71","author":"Liu","year":"2023","journal-title":"J. Agric. Food Chem."},{"issue":"2","key":"10.1016\/j.bios.2024.116313_bib22","doi-asserted-by":"crossref","first-page":"233","DOI":"10.1016\/j.cmi.2022.08.012","volume":"29","author":"Mailhe","year":"2023","journal-title":"Clin. Microbiol. Infect."},{"issue":"10","key":"10.1016\/j.bios.2024.116313_bib23","doi-asserted-by":"crossref","first-page":"e17","DOI":"10.1056\/NEJMp2212931","volume":"389","author":"Nadamuni","year":"2023","journal-title":"N. Engl. J. Med."},{"issue":"17","key":"10.1016\/j.bios.2024.116313_bib24","volume":"228","author":"Nguyen","year":"2023","journal-title":"Biosens. Bioelectron."},{"issue":"29","key":"10.1016\/j.bios.2024.116313_bib25","doi-asserted-by":"crossref","first-page":"11876","DOI":"10.1021\/ja304118z","volume":"134","author":"Pei","year":"2012","journal-title":"J. Am. Chem. Soc."},{"issue":"28","key":"10.1016\/j.bios.2024.116313_bib26","doi-asserted-by":"crossref","first-page":"7362","DOI":"10.1039\/D0SC03084H","volume":"11","author":"Peng","year":"2020","journal-title":"Chem. Sci."},{"key":"10.1016\/j.bios.2024.116313_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2020.128326","volume":"320","author":"Ran","year":"2020","journal-title":"Sensor. Actuator. B Chem."},{"issue":"17","key":"10.1016\/j.bios.2024.116313_bib28","volume":"203","author":"Saito","year":"2022","journal-title":"Biosens. Bioelectron."},{"issue":"10","key":"10.1016\/j.bios.2024.116313_bib29","doi-asserted-by":"crossref","first-page":"4676","DOI":"10.1021\/acs.analchem.1c00371","volume":"93","author":"Sheng","year":"2021","journal-title":"Anal. Chem."},{"issue":"18","key":"10.1016\/j.bios.2024.116313_bib30","doi-asserted-by":"crossref","first-page":"5898","DOI":"10.3390\/molecules27185898","volume":"27","author":"Shi","year":"2022","journal-title":"Molecules"},{"issue":"49","key":"10.1016\/j.bios.2024.116313_bib31","doi-asserted-by":"crossref","first-page":"16646","DOI":"10.1021\/acs.analchem.1c04156","volume":"93","author":"Shi","year":"2021","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2024.116313_bib32","first-page":"7537","volume":"75","author":"Su","year":"2023","journal-title":"Appl. Environ. Microbiol."},{"issue":"6","key":"10.1016\/j.bios.2024.116313_bib33","volume":"172","author":"Wang","year":"2021","journal-title":"Biosens. Bioelectron."},{"issue":"6","key":"10.1016\/j.bios.2024.116313_bib34","volume":"224","author":"Weaver","year":"2023","journal-title":"Biosens. Bioelectron."},{"issue":"14","key":"10.1016\/j.bios.2024.116313_bib35","doi-asserted-by":"crossref","first-page":"7677","DOI":"10.1021\/jacs.3c00841","volume":"145","author":"Xie","year":"2023","journal-title":"J. Am. Chem. Soc."},{"issue":"23","key":"10.1016\/j.bios.2024.116313_bib36","volume":"256","author":"Xing","year":"2023","journal-title":"Talanta"},{"issue":"5","key":"10.1016\/j.bios.2024.116313_bib37","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1039\/D2AN02043B","volume":"148","author":"Ye","year":"2023","journal-title":"Analyst"},{"issue":"1","key":"10.1016\/j.bios.2024.116313_bib38","first-page":"7537","volume":"12","author":"Zeng","year":"2023","journal-title":"Emerg. Microb. Infect."},{"issue":"54","key":"10.1016\/j.bios.2024.116313_bib39","doi-asserted-by":"crossref","first-page":"7562","DOI":"10.1039\/D2CC02821B","volume":"58","author":"Zeng","year":"2022","journal-title":"Chem. Commum."},{"issue":"70","key":"10.1016\/j.bios.2024.116313_bib40","doi-asserted-by":"crossref","first-page":"10235","DOI":"10.1039\/D0CC03993D","volume":"56","author":"Zhang","year":"2020","journal-title":"Chem. Commum."},{"issue":"1","key":"10.1016\/j.bios.2024.116313_bib41","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/j.scib.2020.09.004","volume":"66","author":"Zhao","year":"2021","journal-title":"Sci. Bull."},{"issue":"9","key":"10.1016\/j.bios.2024.116313_bib42","doi-asserted-by":"crossref","first-page":"4949","DOI":"10.1021\/acs.analchem.6b00891","volume":"88","author":"Zhu","year":"2016","journal-title":"Anal. Chem."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095656632400318X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S095656632400318X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T23:56:50Z","timestamp":1719878210000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S095656632400318X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":42,"alternative-id":["S095656632400318X"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2024.116313","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Development of a CRISPR\/Cas12a-mediated aptasensor for Mpox virus antigen detection","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2024.116313","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"116313"}}