{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T04:30:08Z","timestamp":1790137808648,"version":"4.0.1"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.bios.2024.116496","type":"journal-article","created":{"date-parts":[[2024,6,12]],"date-time":"2024-06-12T21:31:15Z","timestamp":1718227875000},"page":"116496","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Precision detection of hepatocellular carcinoma-associated telomerase RNA with SA@Comb-HCR nanosystem"],"prefix":"10.1016","volume":"261","author":[{"given":"Yi","family":"Chen","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hengyi","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaohui","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yufang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Tu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaxi","family":"Mo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shanshan","family":"Tian","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenyu","family":"Sun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoqin","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhizeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jichun","family":"Yang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0166-9027","authenticated-orcid":false,"given":"Yang","family":"Luo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.bios.2024.116496_bib1","first-page":"645","volume":"56","author":"Avilion","year":"1996","journal-title":"Cancer Res."},{"issue":"5","key":"10.1016\/j.bios.2024.116496_bib2","doi-asserted-by":"crossref","first-page":"1871","DOI":"10.1002\/med.21674","volume":"40","author":"Bajaj","year":"2020","journal-title":"Med. Res. Rev."},{"issue":"5","key":"10.1016\/j.bios.2024.116496_bib3","doi-asserted-by":"crossref","first-page":"4896","DOI":"10.1021\/acsnano.2c11922","volume":"17","author":"Bian","year":"2023","journal-title":"ACS Nano"},{"issue":"2","key":"10.1016\/j.bios.2024.116496_bib4","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1038\/ng0296-200","volume":"12","author":"Blasco","year":"1996","journal-title":"Nat. Genet."},{"issue":"19","key":"10.1016\/j.bios.2024.116496_bib5","doi-asserted-by":"crossref","DOI":"10.3390\/cancers14194647","volume":"14","author":"Cerrito","year":"2022","journal-title":"Cancers"},{"key":"10.1016\/j.bios.2024.116496_bib6","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.bios.2019.02.016","volume":"131","author":"Chen","year":"2019","journal-title":"Biosens. Bioelectron."},{"issue":"8","key":"10.1016\/j.bios.2024.116496_bib7","doi-asserted-by":"crossref","first-page":"1682","DOI":"10.1039\/D3AN00088E","volume":"148","author":"Chen","year":"2023","journal-title":"Analyst"},{"issue":"1\u20132","key":"10.1016\/j.bios.2024.116496_bib8","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.ijpharm.2015.05.046","volume":"490","author":"Chen","year":"2015","journal-title":"Int J Pharm"},{"issue":"38","key":"10.1016\/j.bios.2024.116496_bib9","doi-asserted-by":"crossref","first-page":"13019","DOI":"10.1021\/acs.analchem.2c01683","volume":"94","author":"Chen","year":"2022","journal-title":"Anal. Chem."},{"issue":"6","key":"10.1016\/j.bios.2024.116496_bib10","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1021\/bc0100408","volume":"12","author":"Cheung","year":"2001","journal-title":"Bioconjug Chem"},{"issue":"7","key":"10.1016\/j.bios.2024.116496_bib11","doi-asserted-by":"crossref","first-page":"1750","DOI":"10.1021\/acs.accounts.9b00177","volume":"52","author":"Degors","year":"2019","journal-title":"Acc. Chem. Res."},{"issue":"3","key":"10.1016\/j.bios.2024.116496_bib12","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1016\/j.apsb.2022.08.015","volume":"13","author":"Duan","year":"2023","journal-title":"Acta Pharm. Sin. B"},{"issue":"2","key":"10.1016\/j.bios.2024.116496_bib13","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1002\/(SICI)1096-9896(199906)188:2<139::AID-PATH344>3.0.CO;2-6","volume":"188","author":"Heine","year":"1999","journal-title":"J. Pathol."},{"issue":"33","key":"10.1016\/j.bios.2024.116496_bib14","volume":"35","author":"Huang","year":"2023","journal-title":"Adv Mater"},{"key":"10.1016\/j.bios.2024.116496_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.cis.2022.102744","volume":"307","author":"Karim","year":"2022","journal-title":"Adv. Colloid Interface Sci."},{"issue":"34","key":"10.1016\/j.bios.2024.116496_bib16","doi-asserted-by":"crossref","first-page":"13918","DOI":"10.1021\/ja300984b","volume":"134","author":"Li","year":"2012","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bios.2024.116496_bib17","volume":"257","author":"Li","year":"2023","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2024.116496_bib18","volume":"147","author":"Li","year":"2020","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2024.116496_bib19","volume":"142","author":"Li","year":"2019","journal-title":"Biosens. Bioelectron."},{"issue":"1","key":"10.1016\/j.bios.2024.116496_bib20","volume":"1","author":"Liu","year":"2023","journal-title":"IMed"},{"key":"10.1016\/j.bios.2024.116496_bib21","volume":"167","author":"Liu","year":"2020","journal-title":"Biosens. Bioelectron."},{"issue":"11","key":"10.1016\/j.bios.2024.116496_bib22","doi-asserted-by":"crossref","DOI":"10.3390\/ijms23116183","volume":"23","author":"Manganelli","year":"2022","journal-title":"Int. J. Mol. Sci."},{"issue":"12","key":"10.1016\/j.bios.2024.116496_bib23","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.1093\/jjco\/hyw133","volume":"46","author":"Midorikawa","year":"2016","journal-title":"Jpn. J. Clin. Oncol."},{"issue":"31","key":"10.1016\/j.bios.2024.116496_bib24","doi-asserted-by":"crossref","first-page":"11777","DOI":"10.1021\/acs.analchem.3c02014","volume":"95","author":"Mo","year":"2023","journal-title":"Anal. Chem."},{"issue":"12","key":"10.1016\/j.bios.2024.116496_bib25","doi-asserted-by":"crossref","DOI":"10.1002\/jev2.12395","volume":"12","author":"Ou","year":"2023","journal-title":"J. Extracell. Vesicles"},{"issue":"31","key":"10.1016\/j.bios.2024.116496_bib26","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.202302314","volume":"12","author":"Qu","year":"2023","journal-title":"Adv Healthc Mater"},{"key":"10.1016\/j.bios.2024.116496_bib27","volume":"10","author":"Shen","year":"2022","journal-title":"Front. Bioeng. Biotechnol."},{"key":"10.1016\/j.bios.2024.116496_bib28","doi-asserted-by":"crossref","first-page":"97","DOI":"10.3389\/fmicb.2017.00097","volume":"8","author":"Spadari","year":"2017","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.bios.2024.116496_bib29","volume":"19","author":"Sun","year":"2023","journal-title":"Mater Today Bio"},{"issue":"3","key":"10.1016\/j.bios.2024.116496_bib30","doi-asserted-by":"crossref","first-page":"209","DOI":"10.3322\/caac.21660","volume":"71","author":"Sung","year":"2021","journal-title":"CA Cancer J Clin"},{"issue":"3","key":"10.1016\/j.bios.2024.116496_bib31","doi-asserted-by":"crossref","first-page":"3826","DOI":"10.1021\/acsami.2c20024","volume":"15","author":"Wang","year":"2023","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"15","key":"10.1016\/j.bios.2024.116496_bib32","doi-asserted-by":"crossref","first-page":"5965","DOI":"10.1002\/anie.201911712","volume":"59","author":"Wei","year":"2020","journal-title":"Angew Chem. Int. Ed. Engl."},{"key":"10.1016\/j.bios.2024.116496_bib33","doi-asserted-by":"crossref","first-page":"1071","DOI":"10.1016\/j.bios.2016.08.038","volume":"87","author":"Xu","year":"2017","journal-title":"Biosens. Bioelectron."},{"issue":"6","key":"10.1016\/j.bios.2024.116496_bib34","doi-asserted-by":"crossref","first-page":"1709","DOI":"10.1039\/C8SC03305F","volume":"10","author":"Yang","year":"2019","journal-title":"Chem. Sci."},{"issue":"7","key":"10.1016\/j.bios.2024.116496_bib35","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1002\/(SICI)1097-0142(19980401)82:7<1319::AID-CNCR15>3.0.CO;2-9","volume":"82","author":"Yashima","year":"1998","journal-title":"Cancer"},{"issue":"49","key":"10.1016\/j.bios.2024.116496_bib36","doi-asserted-by":"crossref","first-page":"18107","DOI":"10.1021\/acs.analchem.3c03323","volume":"95","author":"Yin","year":"2023","journal-title":"Anal. Chem."},{"issue":"29","key":"10.1016\/j.bios.2024.116496_bib37","doi-asserted-by":"crossref","first-page":"10337","DOI":"10.1021\/acs.analchem.1c05491","volume":"94","author":"Yu","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2024.116496_bib38","volume":"271","author":"Zhang","year":"2022","journal-title":"Spectrochim. Acta Mol. Biomol. Spectrosc."},{"issue":"7","key":"10.1016\/j.bios.2024.116496_bib39","doi-asserted-by":"crossref","first-page":"4237","DOI":"10.1021\/acs.nanolett.9b00030","volume":"19","author":"Zhang","year":"2019","journal-title":"Nano Lett."},{"issue":"2","key":"10.1016\/j.bios.2024.116496_bib40","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1007\/s00604-023-05649-7","volume":"190","author":"Zhang","year":"2023","journal-title":"Microchim. Acta"},{"issue":"4","key":"10.1016\/j.bios.2024.116496_bib41","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1021\/acssensors.1c02717","volume":"7","author":"Zhang","year":"2022","journal-title":"ACS Sens."},{"issue":"32","key":"10.1016\/j.bios.2024.116496_bib42","doi-asserted-by":"crossref","first-page":"35958","DOI":"10.1021\/acsami.0c10962","volume":"12","author":"Zhao","year":"2020","journal-title":"ACS Appl. Mater. Interfaces"},{"issue":"11","key":"10.1016\/j.bios.2024.116496_bib43","doi-asserted-by":"crossref","first-page":"5083","DOI":"10.1021\/acs.nanolett.3c01008","volume":"23","author":"Zhong","year":"2023","journal-title":"Nano Lett."},{"issue":"1","key":"10.1016\/j.bios.2024.116496_bib44","volume":"2","author":"Zhu","year":"2024","journal-title":"IMed"}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566324005013?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566324005013?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T09:36:05Z","timestamp":1739525765000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566324005013"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":44,"alternative-id":["S0956566324005013"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2024.116496","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Precision detection of hepatocellular carcinoma-associated telomerase RNA with SA@Comb-HCR nanosystem","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2024.116496","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"116496"}}