{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T02:03:23Z","timestamp":1792634603390,"version":"4.5.0"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.bios.2024.116512","type":"journal-article","created":{"date-parts":[[2024,6,19]],"date-time":"2024-06-19T23:37:54Z","timestamp":1718840274000},"page":"116512","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["Use of a platform with lens-free shadow imaging technology to monitor natural killer cell activity"],"prefix":"10.1016","volume":"261","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-2047-0118","authenticated-orcid":false,"given":"Inha","family":"Lee","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahyeon","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanghoon","family":"Shin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6302-6326","authenticated-orcid":false,"given":"Samir","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myung-Hyun","family":"Nam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ka-Won","family":"Kang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Byung Soo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung-Dong","family":"Cho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hawon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sunmi","family":"Han","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Su-Hyung","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7990-7390","authenticated-orcid":false,"given":"Sungkyu","family":"Seo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1570-7784","authenticated-orcid":false,"given":"Hyun Sik","family":"Jun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1\u20132","key":"10.1016\/j.bios.2024.116512_bib1","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1016\/j.jim.2004.08.008","article-title":"CD107a as a functional marker for the identification of natural killer cell activity","volume":"294","author":"Alter","year":"2004","journal-title":"J. Immunol. Methods"},{"issue":"13","key":"10.1016\/j.bios.2024.116512_bib2","doi-asserted-by":"crossref","first-page":"2657","DOI":"10.1182\/blood-2009-01-201632","article-title":"Minimal requirement for induction of natural cytotoxicity and intersection of activation signals by inhibitory receptors","volume":"114","author":"Bryceson","year":"2009","journal-title":"Blood"},{"issue":"3","key":"10.1016\/j.bios.2024.116512_bib3","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1182\/blood-2007-09-077438","article-title":"Human natural killer cells","volume":"112","author":"Caligiuri","year":"2008","journal-title":"Blood"},{"issue":"2 Suppl. 2","key":"10.1016\/j.bios.2024.116512_bib4","doi-asserted-by":"crossref","first-page":"S3","DOI":"10.1016\/j.jaci.2009.12.980","article-title":"Overview of the immune response","volume":"125","author":"Chaplin","year":"2010","journal-title":"J. Allergy Clin. Immunol."},{"issue":"1","key":"10.1016\/j.bios.2024.116512_bib5","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1186\/s40425-019-0652-7","article-title":"IL-27 enhances IL-15\/IL-18-mediated activation of human natural killer cells","volume":"7","author":"Choi","year":"2019","journal-title":"J Immunother Cancer"},{"issue":"2\u20133","key":"10.1016\/j.bios.2024.116512_bib6","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1007\/s12026-014-8517-0","article-title":"Effects of stress on immune function: the good, the bad, and the beautiful","volume":"58","author":"Dhabhar","year":"2014","journal-title":"Immunol. Res."},{"key":"10.1016\/j.bios.2024.116512_bib7","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1016\/j.ebiom.2016.02.025","article-title":"Low circulating natural killer cell counts are associated with severe disease in patients with common variable immunodeficiency","volume":"6","author":"Ebbo","year":"2016","journal-title":"EBioMedicine"},{"issue":"50","key":"10.1016\/j.bios.2024.116512_bib8","doi-asserted-by":"crossref","first-page":"21647","DOI":"10.1073\/pnas.1012128107","article-title":"Mature natural killer cells with phenotypic and functional alterations accumulate upon sustained stimulation with IL-15\/IL-15R\u03b1 complexes","volume":"107","author":"Elpek","year":"2010","journal-title":"Proc. Natl. Acad. Sci. USA"},{"key":"10.1016\/j.bios.2024.116512_bib9","series-title":"Methods in Enzymology","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1016\/bs.mie.2019.05.037","article-title":"Chapter Twenty-Seven - 51Cr-release to monitor NK cell cytotoxicity","author":"Elsner","year":"2020"},{"issue":"6","key":"10.1016\/j.bios.2024.116512_bib10","doi-asserted-by":"crossref","first-page":"798","DOI":"10.1016\/j.immuni.2007.04.010","article-title":"Acquisition of murine NK cell cytotoxicity requires the translation of a pre-existing pool of granzyme B and perforin mRNAs","volume":"26","author":"Fehniger","year":"2007","journal-title":"Immunity"},{"issue":"20","key":"10.1016\/j.bios.2024.116512_bib11","article-title":"Efficient ADCC killing of meningioma by avelumab and a high-affinity natural killer cell line","volume":"4","author":"Giles","year":"2019","journal-title":"haNK. JCI Insight"},{"issue":"4","key":"10.1016\/j.bios.2024.116512_bib12","doi-asserted-by":"crossref","first-page":"571","DOI":"10.1016\/j.immuni.2008.02.016","article-title":"NKG2D-deficient mice are defective in tumor surveillance in models of spontaneous malignancy","volume":"28","author":"Guerra","year":"2008","journal-title":"Immunity"},{"issue":"7","key":"10.1016\/j.bios.2024.116512_bib13","doi-asserted-by":"crossref","first-page":"4173","DOI":"10.4049\/jimmunol.176.7.4173","article-title":"A novel NF-kappaB binding site controls human granzyme B gene transcription","volume":"176","author":"Huang","year":"2006","journal-title":"J. Immunol."},{"issue":"4","key":"10.1016\/j.bios.2024.116512_bib14","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1016\/j.chom.2012.03.002","article-title":"Nondegradative role of Atg5-Atg12\/Atg16L1 autophagy protein complex in antiviral activity of interferon gamma","volume":"11","author":"Hwang","year":"2012","journal-title":"Cell Host Microbe"},{"issue":"9244","key":"10.1016\/j.bios.2024.116512_bib15","doi-asserted-by":"crossref","first-page":"1795","DOI":"10.1016\/S0140-6736(00)03231-1","article-title":"Natural cytotoxic activity of peripheral-blood lymphocytes and cancer incidence: an 11-year follow-up study of a general population","volume":"356","author":"Imai","year":"2000","journal-title":"Lancet"},{"issue":"5","key":"10.1016\/j.bios.2024.116512_bib16","doi-asserted-by":"crossref","DOI":"10.4110\/in.2018.18.e33","article-title":"Direct antiviral mechanisms of interferon-gamma","volume":"18","author":"Kang","year":"2018","journal-title":"Immune Netw"},{"key":"10.1016\/j.bios.2024.116512_bib17","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s12979-018-0136-5","article-title":"CD56bright cells respond to stimulation until very advanced age revealing increased expression of cellular protective proteins SIRT1, HSP70 and SOD2","volume":"15","author":"Kaszubowska","year":"2018","journal-title":"Immun. Ageing"},{"issue":"2","key":"10.1016\/j.bios.2024.116512_bib18","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1002\/eji.1830050208","article-title":"\"Natural\" killer cells in the mouse. I. Cytotoxic cells with specificity for mouse Moloney leukemia cells. Specificity and distribution according to genotype","volume":"5","author":"Kiessling","year":"1975","journal-title":"Eur. J. Immunol."},{"issue":"1","key":"10.1016\/j.bios.2024.116512_bib19","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1016\/j.snb.2011.03.032","article-title":"LED and CMOS image sensor based hemoglobin concentration measurement technique","volume":"157","author":"Kim","year":"2011","journal-title":"Sensor. Actuator. B Chem."},{"issue":"11","key":"10.1016\/j.bios.2024.116512_bib20","doi-asserted-by":"crossref","first-page":"2650","DOI":"10.1016\/j.immuni.2021.09.002","article-title":"Early IFN-alpha signatures and persistent dysfunction are distinguishing features of NK cells in severe COVID-19","volume":"54","author":"Kramer","year":"2021","journal-title":"Immunity"},{"key":"10.1016\/j.bios.2024.116512_bib21","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.38867","article-title":"The aryl hydrocarbon receptor and interferon gamma generate antiviral states via transcriptional repression","volume":"7","author":"Kueck","year":"2018","journal-title":"Elife"},{"key":"10.1016\/j.bios.2024.116512_bib22","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/j.snb.2014.02.059","article-title":"CMOS image sensor-based ELISA detector using lens-free shadow imaging platform","volume":"196","author":"Lee","year":"2014","journal-title":"Sensor. Actuator. B Chem."},{"issue":"3","key":"10.1016\/j.bios.2024.116512_bib23","doi-asserted-by":"crossref","first-page":"584","DOI":"10.1016\/j.bbrc.2014.02.040","article-title":"A high-throughput assay of NK cell activity in whole blood and its clinical application","volume":"445","author":"Lee","year":"2014","journal-title":"Biochem. Biophys. Res. Commun."},{"issue":"3","key":"10.1016\/j.bios.2024.116512_bib24","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1046\/j.1365-2141.2001.02995.x","article-title":"Activation of natural killer cells with interleukin 2 (IL-2) and IL-12 increases perforin binding and subsequent lysis of tumour cells","volume":"114","author":"Lehmann","year":"2001","journal-title":"Br. J. Haematol."},{"issue":"1","key":"10.1016\/j.bios.2024.116512_bib25","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.immuni.2013.01.004","article-title":"Interleukin-2 at the crossroads of effector responses, tolerance, and immunotherapy","volume":"38","author":"Liao","year":"2013","journal-title":"Immunity"},{"issue":"1","key":"10.1016\/j.bios.2024.116512_bib26","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/s13045-020-01014-w","article-title":"NK cell-based cancer immunotherapy: from basic biology to clinical development","volume":"14","author":"Liu","year":"2021","journal-title":"J. Hematol. Oncol."},{"issue":"2","key":"10.1016\/j.bios.2024.116512_bib27","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.ccell.2017.06.009","article-title":"Control of metastasis by NK cells","volume":"32","author":"L\u00f3pez-Soto","year":"2017","journal-title":"Cancer Cell"},{"key":"10.1016\/j.bios.2024.116512_bib28","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.60095","article-title":"Peripheral natural killer cells in chronic hepatitis B patients display multiple molecular features of T cell exhaustion","volume":"10","author":"Marotel","year":"2021","journal-title":"Elife"},{"issue":"Suppl. 2","key":"10.1016\/j.bios.2024.116512_bib29","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1186\/s13223-018-0278-1","article-title":"An introduction to immunology and immunopathology","volume":"14","author":"Marshall","year":"2018","journal-title":"Allergy Asthma Clin. Immunol."},{"issue":"9","key":"10.1016\/j.bios.2024.116512_bib30","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1038\/nri886","article-title":"Natural killer cells and pregnancy","volume":"2","author":"Moffett-King","year":"2002","journal-title":"Nat. Rev. Immunol."},{"issue":"11","key":"10.1016\/j.bios.2024.116512_bib31","doi-asserted-by":"crossref","first-page":"1417","DOI":"10.1039\/c000453g","article-title":"Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications","volume":"10","author":"Mudanyali","year":"2010","journal-title":"Lab Chip"},{"issue":"9","key":"10.1016\/j.bios.2024.116512_bib32","doi-asserted-by":"crossref","first-page":"1410","DOI":"10.1128\/CVI.05084-11","article-title":"Reduced degranulation of NK cells in patients with frequently recurring herpes","volume":"18","author":"Murugin","year":"2011","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.bios.2024.116512_bib33","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1016\/j.jim.2018.04.002","article-title":"Quantification of NK cell activity using whole blood: methodological aspects of a new test","volume":"458","author":"Nederby","year":"2018","journal-title":"J. Immunol. Methods"},{"issue":"5","key":"10.1016\/j.bios.2024.116512_bib34","doi-asserted-by":"crossref","first-page":"282","DOI":"10.1038\/s41577-019-0139-2","article-title":"Immunometabolism and natural killer cell responses","volume":"19","author":"O'Brien","year":"2019","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bios.2024.116512_bib35","doi-asserted-by":"crossref","first-page":"1124","DOI":"10.3389\/fimmu.2017.01124","article-title":"The molecular mechanism of natural killer cells function and its importance in cancer immunotherapy","volume":"8","author":"Paul","year":"2017","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bios.2024.116512_bib36","doi-asserted-by":"crossref","first-page":"231","DOI":"10.3389\/fcimb.2020.00231","article-title":"Targeting natural killer cells for improved immunity and control of the adaptive immune response","volume":"10","author":"Pierce","year":"2020","journal-title":"Front. Cell. Infect. Microbiol."},{"issue":"3","key":"10.1016\/j.bios.2024.116512_bib37","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0150998","article-title":"Ionomycin treatment renders NK cells hyporesponsive","volume":"11","author":"Romera-C\u00e1rdenas","year":"2016","journal-title":"PLoS One"},{"key":"10.1016\/j.bios.2024.116512_bib38","doi-asserted-by":"crossref","first-page":"577","DOI":"10.1016\/j.snb.2015.10.097","article-title":"Staining-free cell viability measurement technique using lens-free shadow imaging platform","volume":"224","author":"Roy","year":"2016","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.bios.2024.116512_bib39","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1016\/j.snb.2014.05.011","article-title":"A simple and low-cost device performing blood cell counting based on lens-free shadow imaging technique","volume":"201","author":"Roy","year":"2014","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.bios.2024.116512_bib40","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1016\/j.bios.2014.10.040","article-title":"Low-cost telemedicine device performing cell and particle size measurement based on lens-free shadow imaging technology","volume":"67","author":"Roy","year":"2015","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2024.116512_bib41","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.bios.2016.07.115","article-title":"A review of recent progress in lens-free imaging and sensing","volume":"88","author":"Roy","year":"2017","journal-title":"Biosens. Bioelectron."},{"issue":"4","key":"10.1016\/j.bios.2024.116512_bib42","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1111\/j.1365-2567.2010.03360.x","article-title":"Natural killer cells in human autoimmune diseases","volume":"131","author":"Schleinitz","year":"2010","journal-title":"Immunology"},{"issue":"2","key":"10.1016\/j.bios.2024.116512_bib43","doi-asserted-by":"crossref","first-page":"47","DOI":"10.3390\/bios12020047","article-title":"Field-portable leukocyte classification device based on lens-free shadow imaging technique","volume":"12","author":"Seo","year":"2022","journal-title":"Biosensors"},{"issue":"1","key":"10.1016\/j.bios.2024.116512_bib44","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3390\/s18010085","article-title":"A field-portable cell analyzer without a microscope and reagents","volume":"18","author":"Seo","year":"2017","journal-title":"Sensors"},{"key":"10.1016\/j.bios.2024.116512_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.algal.2020.102063","article-title":"Rapid eco-toxicity analysis of hazardous and noxious substances (HNS) using morphological change detection in Dunaliella tertiolecta","volume":"51","author":"Seo","year":"2020","journal-title":"Algal Res."},{"issue":"6","key":"10.1016\/j.bios.2024.116512_bib46","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1039\/B813943A","article-title":"Lensfree holographic imaging for on-chip cytometry and diagnostics","volume":"9","author":"Seo","year":"2009","journal-title":"Lab Chip"},{"key":"10.1016\/j.bios.2024.116512_bib47","doi-asserted-by":"crossref","DOI":"10.1016\/j.watres.2023.119585","article-title":"Field-portable seawater toxicity monitoring platform using lens-free shadow imaging technology","volume":"230","author":"Shin","year":"2023","journal-title":"Water Res."},{"issue":"2","key":"10.1016\/j.bios.2024.116512_bib48","doi-asserted-by":"crossref","DOI":"10.1136\/jitc-2020-002044","article-title":"TGF\u03b2 drives NK cell metabolic dysfunction in human metastatic breast cancer","volume":"9","author":"Slattery","year":"2021","journal-title":"J Immunother Cancer"},{"issue":"4","key":"10.1016\/j.bios.2024.116512_bib49","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1016\/j.coi.2005.05.002","article-title":"Ex vivo analysis of T-cell function","volume":"17","author":"Suni","year":"2005","journal-title":"Curr. Opin. Immunol."},{"issue":"4","key":"10.1016\/j.bios.2024.116512_bib50","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1111\/j.1365-3083.2011.02667.x","article-title":"Evaluation of a flow cytometry-based assay for natural killer cell activity in clinical settings","volume":"75","author":"Valiathan","year":"2012","journal-title":"Scand. J. Immunol."},{"issue":"3","key":"10.1016\/j.bios.2024.116512_bib51","doi-asserted-by":"crossref","first-page":"604","DOI":"10.1038\/s41423-020-00557-9","article-title":"Unique immunological profile in patients with COVID-19","volume":"18","author":"Varchetta","year":"2021","journal-title":"Cell. Mol. Immunol."},{"issue":"9","key":"10.1016\/j.bios.2024.116512_bib52","doi-asserted-by":"crossref","DOI":"10.4161\/onci.26011","article-title":"Monitoring NK cell activity in patients with hematological malignancies","volume":"2","author":"Viel","year":"2013","journal-title":"OncoImmunology"},{"issue":"5","key":"10.1016\/j.bios.2024.116512_bib53","doi-asserted-by":"crossref","first-page":"503","DOI":"10.1038\/ni1582","article-title":"Functions of natural killer cells","volume":"9","author":"Vivier","year":"2008","journal-title":"Nat. Immunol."},{"issue":"10","key":"10.1016\/j.bios.2024.116512_bib54","doi-asserted-by":"crossref","first-page":"3183","DOI":"10.1182\/blood.V95.10.3183","article-title":"Interleukin-2 enhances the response of natural killer cells to interleukin-12 through up-regulation of the interleukin-12 receptor and STAT4","volume":"95","author":"Wang","year":"2000","journal-title":"Blood"},{"issue":"20","key":"10.1016\/j.bios.2024.116512_bib55","doi-asserted-by":"crossref","first-page":"11301","DOI":"10.1073\/pnas.191361398","article-title":"Digital in-line holography for biological applications","volume":"98","author":"Xu","year":"2001","journal-title":"Proc. Natl. Acad. Sci. U.S.A."},{"issue":"4","key":"10.1016\/j.bios.2024.116512_bib56","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0125211","article-title":"Analysis of GzmbCre as a model system for gene deletion in the natural killer cell lineage","volume":"10","author":"Xu","year":"2015","journal-title":"PLoS One"},{"issue":"16","key":"10.1016\/j.bios.2024.116512_bib57","doi-asserted-by":"crossref","first-page":"3015","DOI":"10.1039\/D2LC00388K","article-title":"Highly accurate multiprotein detection on a digital ELISA platform","volume":"22","author":"Yang","year":"2022","journal-title":"Lab Chip"},{"key":"10.1016\/j.bios.2024.116512_bib58","doi-asserted-by":"crossref","first-page":"25","DOI":"10.3389\/fimmu.2017.00025","article-title":"Regulation of NK cell activation and effector functions by the IL-12 family of cytokines: the case of IL-27","volume":"8","author":"Zwirner","year":"2017","journal-title":"Front. Immunol."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566324005177?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566324005177?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T09:36:50Z","timestamp":1739525810000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566324005177"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":58,"alternative-id":["S0956566324005177"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2024.116512","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Use of a platform with lens-free shadow imaging technology to monitor natural killer cell activity","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2024.116512","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"116512"}}