{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T19:17:27Z","timestamp":1793128647942,"version":"4.5.0"},"reference-count":48,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T00:00:00Z","timestamp":1724284800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"FAPESP","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000001","name":"National Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000001","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100010629","name":"Fulbright Association","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100010629","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2024,10]]},"DOI":"10.1016\/j.bios.2024.116526","type":"journal-article","created":{"date-parts":[[2024,6,25]],"date-time":"2024-06-25T14:12:45Z","timestamp":1719324765000},"page":"116526","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"special_numbering":"C","title":["All-MXene electronic tongue for neurotransmitters detection"],"prefix":"10.1016","volume":"262","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0858-0364","authenticated-orcid":false,"given":"Murilo H.M.","family":"Facure","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7235-8261","authenticated-orcid":false,"given":"Gulnaz","family":"Gahramanova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danzhen","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Teng","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1274-8484","authenticated-orcid":false,"given":"Christopher E.","family":"Shuck","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiza A.","family":"Mercante","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5592-0627","authenticated-orcid":false,"given":"Daniel S.","family":"Correa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yury","family":"Gogotsi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bios.2024.116526_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2019.115766","article-title":"Current advances in the detection of neurotransmitters by nanomaterials: an update","volume":"123","author":"Arumugasamy","year":"2020","journal-title":"TrAC, Trends Anal. Chem."},{"key":"10.1016\/j.bios.2024.116526_bib2","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.bios.2018.09.002","article-title":"Clinical implications and electrochemical biosensing of monoamine neurotransmitters in body fluids, in vitro, in vivo, and ex vivo models","volume":"121","author":"Baranwal","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2024.116526_bib3","doi-asserted-by":"crossref","first-page":"496","DOI":"10.1016\/j.bios.2013.03.063","article-title":"An amperometric glutamate biosensor based on immobilization of glutamate oxidase onto carboxylated multiwalled carbon nanotubes\/gold nanoparticles\/chitosan composite film modified Au electrode","volume":"47","author":"Batra","year":"2013","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2024.116526_bib4","doi-asserted-by":"crossref","first-page":"3064","DOI":"10.1039\/D2AY00736C","article-title":"Quantification of phosphatides in sunflower oils using a potentiometric e-tongue","volume":"14","author":"Belugina","year":"2022","journal-title":"Anal. Methods"},{"key":"10.1016\/j.bios.2024.116526_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.synthmet.2020.116354","article-title":"Sensitive biosensing of neurotransmitter: 2D material wrapped nanotubes and MnO2 composites for the detection of acetylcholine","volume":"263","author":"Chauhan","year":"2020","journal-title":"Synth. Met."},{"key":"10.1016\/j.bios.2024.116526_bib6","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1016\/j.bios.2016.06.047","article-title":"An electrochemical sensor for detection of neurotransmitter-acetylcholine using metal nanoparticles, 2D material and conducting polymer modified electrode","volume":"89","author":"Chauhan","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2024.116526_bib7","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1016\/j.procbio.2019.12.016","article-title":"Recent advancement in nanosensors for neurotransmitters detection: present and future perspective","volume":"91","author":"Chauhan","year":"2020","journal-title":"Process Biochemistry"},{"key":"10.1016\/j.bios.2024.116526_bib8","doi-asserted-by":"crossref","first-page":"7319","DOI":"10.1021\/acs.analchem.2c00684","article-title":"Superhydrophobic functionalized Ti3C2Tx MXene-based skin-attachable and wearable electrochemical pH sensor for real-time sweat detection","volume":"94","author":"Chen","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2024.116526_bib9","doi-asserted-by":"crossref","first-page":"2225","DOI":"10.1021\/acssensors.2c00658","article-title":"N\u2013p-Conductor transition of gas sensing behaviors in Mo2CTx MXene","volume":"7","author":"Choi","year":"2022","journal-title":"ACS Sens."},{"key":"10.1016\/j.bios.2024.116526_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2021.129696","article-title":"Two-dimensional MoS2-based impedimetric electronic tongue for the discrimination of endocrine disrupting chemicals using machine learning","volume":"336","author":"Christinelli","year":"2021","journal-title":"Sens Actuators B Chem"},{"key":"10.1016\/j.bios.2024.116526_bib11","doi-asserted-by":"crossref","first-page":"2827","DOI":"10.1039\/C8AN01934G","article-title":"Paper based electronic tongue - a low-cost solution for the distinction of sugar type and apple juice brand","volume":"144","author":"Daikuzono","year":"2019","journal-title":"Analyst"},{"key":"10.1016\/j.bios.2024.116526_bib12","doi-asserted-by":"crossref","first-page":"566","DOI":"10.1016\/j.snb.2016.02.080","article-title":"The use of an e-tongue for discriminating ethanol\/water mixtures and determination of their water content","volume":"230","author":"De Queiroz","year":"2016","journal-title":"Sens Actuators B Chem"},{"key":"10.1016\/j.bios.2024.116526_bib13","series-title":"Electronic Tongues","first-page":"6","article-title":"Fundamentals and applications of impedimetric electronic tongues","author":"Facure","year":"2021"},{"key":"10.1016\/j.bios.2024.116526_bib14","series-title":"Encyclopedia of Sensors and Biosensors","first-page":"567","article-title":"Electrical impedance-based electronic tongues","author":"Facure","year":"2023"},{"key":"10.1016\/j.bios.2024.116526_bib15","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1016\/j.talanta.2017.02.005","article-title":"Detection of trace levels of organophosphate pesticides using an electronic tongue based on graphene hybrid nanocomposites","volume":"167","author":"Facure","year":"2017","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2024.116526_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2020.121039","article-title":"Impedimetric electronic tongue based on molybdenum disulfide and graphene oxide for monitoring antibiotics in liquid media","volume":"217","author":"Facure","year":"2020","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2024.116526_bib17","doi-asserted-by":"crossref","first-page":"28432","DOI":"10.1021\/acs.jpcc.6b09109","article-title":"Effects of applied potential and water intercalation on the surface chemistry of Ti2C and Mo2C MXenes","volume":"120","author":"Fredrickson","year":"2016","journal-title":"J. Phys. Chem. C"},{"key":"10.1016\/j.bios.2024.116526_bib18","doi-asserted-by":"crossref","first-page":"751","DOI":"10.1016\/j.foodchem.2019.03.107","article-title":"Analysis of musts and wines by means of a bio-electronic tongue based on tyrosinase and glucose oxidase using polypyrrole\/gold nanoparticles as the electron mediator","volume":"289","author":"Garcia-Hernandez","year":"2019","journal-title":"Food Chem."},{"key":"10.1016\/j.bios.2024.116526_bib19","series-title":"MXenes: from Discovery to Applications of Two-Dimensional Metal Carbides and Nitrides","author":"Gogotsi","year":"2023"},{"key":"10.1016\/j.bios.2024.116526_bib20","doi-asserted-by":"crossref","first-page":"8491","DOI":"10.1021\/acsnano.9b06394","article-title":"The rise of MXenes","volume":"13","author":"Gogotsi","year":"2019","journal-title":"ACS Nano"},{"key":"10.1016\/j.bios.2024.116526_bib21","doi-asserted-by":"crossref","first-page":"770","DOI":"10.3390\/nano13040770","article-title":"Lamivudine and zidovudine-loaded nanostructures: green chemistry preparation for pediatric oral administration","volume":"13","author":"Guedes","year":"2023","journal-title":"Nanomaterials"},{"key":"10.1016\/j.bios.2024.116526_bib22","doi-asserted-by":"crossref","DOI":"10.1002\/adma.201804779","article-title":"Electronic and optical properties of 2D transition metal carbides and nitrides (MXenes)","volume":"30","author":"Hantanasirisakul","year":"2018","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bios.2024.116526_bib23","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1021\/acssensors.3c00082","article-title":"Recent advances in the development and characterization of electrochemical and electrical biosensors for small molecule neurotransmitters","volume":"8","author":"He","year":"2023","journal-title":"ACS Sens."},{"key":"10.1016\/j.bios.2024.116526_bib24","doi-asserted-by":"crossref","first-page":"6560","DOI":"10.1039\/C5CC00980D","article-title":"Mo2Ga2C: a new ternary nanolaminated carbide","volume":"51","author":"Hu","year":"2015","journal-title":"Chem. Commun."},{"key":"10.1016\/j.bios.2024.116526_bib25","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3390\/s19235113","article-title":"Electronic tongues for inedible media","volume":"19","author":"Kirsanov","year":"2019","journal-title":"Sensors"},{"key":"10.1016\/j.bios.2024.116526_bib26","doi-asserted-by":"crossref","first-page":"10434","DOI":"10.1021\/acsami.9b21765","article-title":"Room-temperature, highly durable Ti3C2Tx MXene\/graphene hybrid fibers for NH3 gas sensing","volume":"12","author":"Lee","year":"2020","journal-title":"ACS Appl. Mater. Interfaces"},{"key":"10.1016\/j.bios.2024.116526_bib27","article-title":"Patterning of wafer-scale MXene films for high-performance image sensor arrays","volume":"34","author":"Li","year":"2022","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bios.2024.116526_bib28","doi-asserted-by":"crossref","first-page":"16140","DOI":"10.1021\/acsnano.0c08671","article-title":"2H-MoS2 on Mo2CTx MXene nanohybrid for efficient and durable electrocatalytic hydrogen evolution","volume":"14","author":"Lim","year":"2020","journal-title":"ACS Nano"},{"key":"10.1016\/j.bios.2024.116526_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2022.112214","article-title":"Electronic tongue and electronic nose for food quality and safety","volume":"162","author":"Lu","year":"2022","journal-title":"Food Res. Int."},{"key":"10.1016\/j.bios.2024.116526_bib30","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.bios.2016.01.050","article-title":"Electronic tongue for microcystin screening in waters","volume":"80","author":"Lvova","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2024.116526_bib31","doi-asserted-by":"crossref","DOI":"10.3390\/s18082584","article-title":"Electronic tongue for brand uniformity control: a case study of apulian red wines recognition and defects evaluation","volume":"18","author":"Lvova","year":"2018","journal-title":"Sensors"},{"key":"10.1016\/j.bios.2024.116526_bib32","doi-asserted-by":"crossref","first-page":"865","DOI":"10.1246\/bcsj.20180005","article-title":"Efficient praziquantel encapsulation into polymer microcapsules and taste masking evaluation using an electronic tongue","volume":"91","author":"Machado","year":"2018","journal-title":"Bull. Chem. Soc. Jpn."},{"key":"10.1016\/j.bios.2024.116526_bib33","doi-asserted-by":"crossref","first-page":"4024","DOI":"10.1021\/acschemneuro.0c00355","article-title":"\u201cNano\u201d: an emerging avenue in electrochemical detection of neurotransmitters","volume":"11","author":"Madhurantakam","year":"2020","journal-title":"ACS Chem. Neurosci."},{"key":"10.1016\/j.bios.2024.116526_bib34","doi-asserted-by":"crossref","DOI":"10.1002\/adom.202001563","article-title":"The broad chromatic range of two-dimensional transition metal carbides","volume":"9","author":"Maleski","year":"2021","journal-title":"Adv. Opt. Mater."},{"key":"10.1016\/j.bios.2024.116526_bib35","doi-asserted-by":"crossref","first-page":"3501","DOI":"10.1002\/adma.201500604","article-title":"Amine-assisted delamination of Nb2C MXene for Li-ion energy storage devices","volume":"27","author":"Mashtalir","year":"2015","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bios.2024.116526_bib36","doi-asserted-by":"crossref","DOI":"10.1016\/j.snr.2021.100050","article-title":"Design of a bioelectronic tongue for glucose monitoring using zinc oxide nanofibers and graphene derivatives","volume":"3","author":"Mercante","year":"2021","journal-title":"Sensors and Actuators Reports"},{"key":"10.1016\/j.bios.2024.116526_bib37","doi-asserted-by":"crossref","first-page":"15966","DOI":"10.1021\/ja405735d","article-title":"New two-dimensional niobium and vanadium carbides as promising materials for Li-ion batteries","volume":"135","author":"Naguib","year":"2013","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bios.2024.116526_bib38","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1038\/nbt0308-303","article-title":"What is principal component analysis?","volume":"26","author":"Ringner","year":"2008","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.bios.2024.116526_bib39","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1039\/c0an00292e","article-title":"Recent advances in electronic tongues","volume":"135","author":"Riul","year":"2010","journal-title":"Analyst"},{"key":"10.1016\/j.bios.2024.116526_bib40","doi-asserted-by":"crossref","DOI":"10.1002\/mame.202170039","article-title":"Graphene and MXene-based sponge pressure sensor array for rectal model pressure detection","volume":"306","author":"Sang","year":"2021","journal-title":"Macromol. Mater. Eng."},{"key":"10.1016\/j.bios.2024.116526_bib41","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202306815","article-title":"Enhancing charge storage of Mo2Ti2C3 MXene by partial oxidation","volume":"34","author":"Saraf","year":"2024","journal-title":"Adv. Funct. Mater."},{"key":"10.1016\/j.bios.2024.116526_bib42","doi-asserted-by":"crossref","first-page":"387","DOI":"10.1016\/j.snb.2019.03.125","article-title":"Ternary nanocomposites based on cellulose nanowhiskers, silver nanoparticles and electrospun nanofibers: use in an electronic tongue for heavy metal detection","volume":"290","author":"Teodoro","year":"2019","journal-title":"Sens Actuators B Chem"},{"key":"10.1016\/j.bios.2024.116526_bib43","doi-asserted-by":"crossref","DOI":"10.1126\/science.abf1581","article-title":"The world of two-dimensional carbides and nitrides (MXenes)","volume":"372","author":"VahidMohammadi","year":"2021","journal-title":"Science"},{"key":"10.1016\/j.bios.2024.116526_bib44","doi-asserted-by":"crossref","first-page":"1965","DOI":"10.1351\/pac200577111965","article-title":"Nonspecific sensor arrays (\u201celectronic tongue\u201d) for chemical analysis of liquids","volume":"77","author":"Vlasov","year":"2005","journal-title":"Pure Appl. Chem."},{"key":"10.1016\/j.bios.2024.116526_bib45","first-page":"848","article-title":"Multisensor system with an array of chemical sensors and artificial neural networks (electronic tongue) for quantitative analysis of multicomponent aqueous solutions","volume":"69","author":"Vlasov","year":"1996","journal-title":"Russ. J. Appl. Chem."},{"key":"10.1016\/j.bios.2024.116526_bib46","article-title":"Implantable aptamer\u2013field-effect transistor neuroprobes for in vivo neurotransmitter monitoring","volume":"7","author":"Zhao","year":"2023","journal-title":"Sci. Adv."},{"key":"10.1016\/j.bios.2024.116526_bib47","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.ensm.2017.03.012","article-title":"Li-ion uptake and increase in interlayer spacing of Nb4C3 MXene","volume":"8","author":"Zhao","year":"2017","journal-title":"Energy Storage Mater."},{"key":"10.1016\/j.bios.2024.116526_bib48","doi-asserted-by":"crossref","DOI":"10.1016\/j.elecom.2022.107380","article-title":"Effect of pinholes in Nb4C3 MXene sheets on its electrochemical behavior in aqueous electrolytes","volume":"142","author":"Zhao","year":"2022","journal-title":"Electrochem. Commun."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566324005311?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566324005311?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,11,16]],"date-time":"2024-11-16T18:21:55Z","timestamp":1731781315000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566324005311"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10]]},"references-count":48,"alternative-id":["S0956566324005311"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2024.116526","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"All-MXene electronic tongue for neurotransmitters detection","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2024.116526","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"116526"}}