{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T17:52:35Z","timestamp":1792691555586,"version":"4.5.0"},"reference-count":32,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T00:00:00Z","timestamp":1727740800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100017607","name":"Shenzhen Basic Research Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100017607","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Guangdong Provincial Natural Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012165","name":"Key Technologies Research and Development Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012165","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2025,1]]},"DOI":"10.1016\/j.bios.2024.116825","type":"journal-article","created":{"date-parts":[[2024,10,1]],"date-time":"2024-10-01T19:25:51Z","timestamp":1727810751000},"page":"116825","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":46,"special_numbering":"C","title":["Quantitative detection of circular RNA and microRNA at point-of-care using droplet digital CRISPR\/Cas13a platform"],"prefix":"10.1016","volume":"267","author":[{"given":"Ke","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haofan","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunzhu","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minmin","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaopeng","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhenheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunxin","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianhua","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Keying","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4619-6814","authenticated-orcid":false,"given":"Jiasi","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bios.2024.116825_bib1","doi-asserted-by":"crossref","DOI":"10.1126\/science.aaf5573","volume":"353","author":"Abudayyeh","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.bios.2024.116825_bib2","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1038\/nrc.2017.99","volume":"18","author":"Anastasiadou","year":"2018","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.bios.2024.116825_bib3","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.omtn.2018.05.009","volume":"12","author":"Barbagallo","year":"2018","journal-title":"Mol. Ther. Nucleic Acids"},{"key":"10.1016\/j.bios.2024.116825_bib4","doi-asserted-by":"crossref","first-page":"e179","DOI":"10.1093\/nar\/gni178","volume":"33","author":"Chen","year":"2005","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bios.2024.116825_bib5","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1038\/nature11247","volume":"489","author":"Consortium","year":"2012","journal-title":"Nature"},{"key":"10.1016\/j.bios.2024.116825_bib6","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/nature19802","volume":"538","author":"East-Seletsky","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.bios.2024.116825_bib7","doi-asserted-by":"crossref","first-page":"374","DOI":"10.1089\/nat.2014.0506","volume":"24","author":"Eckstein","year":"2014","journal-title":"Nucleic Acid Therapeut."},{"key":"10.1016\/j.bios.2024.116825_bib8","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.ccell.2019.01.019","volume":"35","author":"Esposito","year":"2019","journal-title":"Cancer Cell"},{"key":"10.1016\/j.bios.2024.116825_bib9","doi-asserted-by":"crossref","first-page":"192","DOI":"10.2144\/btn-2019-0065","volume":"67","author":"Forero","year":"2019","journal-title":"Biotechniques"},{"key":"10.1016\/j.bios.2024.116825_bib10","doi-asserted-by":"crossref","first-page":"114","DOI":"10.1039\/C8AN01572D","volume":"144","author":"Gillespie","year":"2018","journal-title":"Analyst"},{"key":"10.1016\/j.bios.2024.116825_bib11","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1126\/science.aam9321","volume":"356","author":"Gootenberg","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.bios.2024.116825_bib12","first-page":"165","volume":"vol. 5","author":"Jintao","year":"2024"},{"key":"10.1016\/j.bios.2024.116825_bib13","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1038\/onc.2017.361","volume":"37","author":"Kristensen","year":"2018","journal-title":"Oncogene"},{"key":"10.1016\/j.bios.2024.116825_bib14","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1038\/s41571-021-00585-y","volume":"19","author":"Kristensen","year":"2022","journal-title":"Nat. Rev. Clin. Oncol."},{"key":"10.1016\/j.bios.2024.116825_bib15","volume":"248","author":"Li","year":"2023","journal-title":"Pathol. Res. Pract."},{"key":"10.1016\/j.bios.2024.116825_bib16","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1038\/s41419-018-1287-1","volume":"10","author":"Liu","year":"2019","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.bios.2024.116825_bib17","doi-asserted-by":"crossref","first-page":"3781","DOI":"10.7150\/ijbs.85063","volume":"19","author":"Long","year":"2023","journal-title":"Int. J. Biol. Sci."},{"key":"10.1016\/j.bios.2024.116825_bib18","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1038\/s41569-023-00952-5","volume":"21","author":"Mably","year":"2024","journal-title":"Nat. Rev. Cardiol."},{"key":"10.1016\/j.bios.2024.116825_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2021.123066","volume":"238","author":"Mi","year":"2022","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2024.116825_bib20","doi-asserted-by":"crossref","DOI":"10.1002\/anie.202309135","volume":"62","author":"Moro","year":"2023","journal-title":"Angew Chem. Int. Ed. Engl."},{"key":"10.1016\/j.bios.2024.116825_bib21","author":"Nemeth","year":"2023","journal-title":"Nat. Rev. Genet."},{"key":"10.1016\/j.bios.2024.116825_bib22","doi-asserted-by":"crossref","DOI":"10.1371\/annotation\/f782282b-eefa-4c8d-985c-b1484e845855","volume":"9","author":"Salzman","year":"2013","journal-title":"PLoS Genet."},{"key":"10.1016\/j.bios.2024.116825_bib23","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1186\/s12943-018-0897-7","volume":"17","author":"Sun","year":"2018","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.bios.2024.116825_bib24","doi-asserted-by":"crossref","first-page":"569","DOI":"10.1038\/nri855","volume":"2","author":"Thery","year":"2002","journal-title":"Nat. Rev. Immunol."},{"key":"10.1016\/j.bios.2024.116825_bib25","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/j.cell.2014.09.005","volume":"159","author":"Vicens","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.bios.2024.116825_bib26","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1186\/s12943-020-01298-z","volume":"20","author":"Wang","year":"2021","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.bios.2024.116825_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2022.108123","volume":"234","author":"Wang","year":"2022","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.bios.2024.116825_bib28","volume":"375","author":"Wang","year":"2023","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.bios.2024.116825_bib29","first-page":"966","volume":"95","author":"Xue","year":"2023","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2024.116825_bib30","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1021\/jacs.8b09073","volume":"141","author":"Yen","year":"2019","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bios.2024.116825_bib31","doi-asserted-by":"crossref","first-page":"4643","DOI":"10.1021\/acs.nanolett.1c00715","volume":"21","author":"Yue","year":"2021","journal-title":"Nano Lett."},{"key":"10.1016\/j.bios.2024.116825_bib32","doi-asserted-by":"crossref","first-page":"67","DOI":"10.1186\/s13045-023-01452-2","volume":"16","author":"Zhang","year":"2023","journal-title":"J. Hematol. Oncol."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566324008327?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566324008327?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,13]],"date-time":"2024-12-13T11:39:41Z","timestamp":1734089981000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566324008327"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1]]},"references-count":32,"alternative-id":["S0956566324008327"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2024.116825","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Quantitative detection of circular RNA and microRNA at point-of-care using droplet digital CRISPR\/Cas13a platform","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2024.116825","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"116825"}}