{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,2]],"date-time":"2026-10-02T02:27:41Z","timestamp":1790908061910,"version":"4.1.0"},"reference-count":41,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,3,1]],"date-time":"2025-03-01T00:00:00Z","timestamp":1740787200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["CNPq\/Brazil 164792\/2022-8"],"award-info":[{"award-number":["CNPq\/Brazil 164792\/2022-8"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002322","name":"Coordination of Higher Education Personnel Improvement","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"State of Sao Paulo Research Foundation","doi-asserted-by":"publisher","award":["2020\/07539\\u20136"],"award-info":[{"award-number":["2020\/07539\\u20136"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001807","name":"State of Sao Paulo Research Foundation","doi-asserted-by":"publisher","award":["2020\/04635\\u20134"],"award-info":[{"award-number":["2020\/04635\\u20134"]}],"id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2025,3]]},"DOI":"10.1016\/j.bios.2024.117022","type":"journal-article","created":{"date-parts":[[2024,12,3]],"date-time":"2024-12-03T03:23:49Z","timestamp":1733196229000},"page":"117022","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":10,"special_numbering":"C","title":["Electrochemical magneto-immunoassay based on Mycobacterium leprae mimotope for serological diagnosis of leprosy"],"prefix":"10.1016","volume":"271","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9870-1950","authenticated-orcid":false,"given":"Sth\u00e9fane Valle","family":"de Almeida","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5318-4048","authenticated-orcid":false,"given":"Pablo Roberto Lins","family":"da Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3678-0892","authenticated-orcid":false,"given":"Wilson Tiago","family":"Fonseca","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T\u00e1ssia Regina","family":"de Oliveira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0968-8270","authenticated-orcid":false,"given":"Cristiane","family":"Zocatelli Ribeiro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1532-2304","authenticated-orcid":false,"given":"Juliana","family":"de Moura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronaldo Censi","family":"Faria","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bios.2024.117022_bib1","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1007\/s11220-023-00413-w","article-title":"A review of quartz crystal microbalance for chemical and biological sensing applications","volume":"24","author":"Alanazi","year":"2023","journal-title":"Sens. Imag."},{"key":"10.1016\/j.bios.2024.117022_bib2","doi-asserted-by":"crossref","DOI":"10.1186\/1471-2334-13-42","article-title":"Identification of mimotopes of Mycobacterium leprae as potential diagnostic reagents","volume":"13","author":"Alban","year":"2013","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.bios.2024.117022_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1371\/journal.pone.0106222","article-title":"Phage display and synthetic peptides as promising biotechnological tools for the serological diagnosis of leprosy","volume":"9","author":"Alban","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.bios.2024.117022_bib4","doi-asserted-by":"crossref","DOI":"10.1186\/s13568-019-0928-9","article-title":"Recombinant polypeptide of Mycobacterium leprae as a potential tool for serological detection of leprosy","volume":"9","author":"Barbosa","year":"2019","journal-title":"Amb. Express"},{"key":"10.1016\/j.bios.2024.117022_bib5","series-title":"Guia de procedimentos t\u00e9cnicos: baciloscopia em hansen\u00edase","year":"2010"},{"key":"10.1016\/j.bios.2024.117022_bib6","doi-asserted-by":"crossref","first-page":"1209","DOI":"10.1016\/S0140-6736(04)15952-7","article-title":"Leprosy","volume":"363","author":"Britton","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.bios.2024.117022_bib7","first-page":"11","article-title":"What happens when Schwann cells are exposed to Mycobacterium leprae \u2013 a systematic review, IBRO Neurosci","volume":"15","author":"Br\u00fcgger","year":"2023","journal-title":"Rep."},{"key":"10.1016\/j.bios.2024.117022_bib8","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2023.124277","article-title":"Electrochemical magneto-immunoassay for detection of zika virus antibody in human serum","volume":"256","author":"Castro","year":"2023","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2024.117022_bib9","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1590\/S0037-86822008000700004","article-title":"Sorologia da hansen\u00edase utilizando PGL-I: revis\u00e3o sistem\u00e1tica","volume":"41","author":"Moura","year":"2008","journal-title":"Rev. Soc. Bras. Med. Trop."},{"key":"10.1016\/j.bios.2024.117022_bib10","doi-asserted-by":"crossref","first-page":"1078","DOI":"10.1016\/j.jiph.2019.12.011","article-title":"Diagnostic accuracy of tests using recombinant protein antigens of Mycobacterium leprae for leprosy: a systematic review","volume":"13","author":"de Oliveira","year":"2020","journal-title":"J. Infect. Publ. Health"},{"key":"10.1016\/j.bios.2024.117022_bib11","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/j.talanta.2018.05.027","article-title":"Engineered biomarkers for leprosy diagnosis using labeled and label-free analysis","volume":"187","author":"de Santana","year":"2018","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2024.117022_bib12","doi-asserted-by":"crossref","first-page":"1400","DOI":"10.1128\/CVI.00299-07","article-title":"Use of protein antigens for early serological diagnosis of leprosy","volume":"14","author":"Duthie","year":"2007","journal-title":"Clin. Vaccine Immunol."},{"key":"10.1016\/j.bios.2024.117022_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2022.123422","article-title":"Amperometric immunosensor developed for sensitive detection of SARS-CoV-2 spike S1 protein in combined with portable device","volume":"244","author":"Erdem","year":"2022","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2024.117022_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioelechem.2023.108619","article-title":"Smartphone-assisted paper-based electrochemical immunosensor for SARS-CoV-2 detection in saliva","volume":"156","author":"Fabiani","year":"2024","journal-title":"Bioelectrochemistry"},{"key":"10.1016\/j.bios.2024.117022_bib15","doi-asserted-by":"crossref","first-page":"3040","DOI":"10.1016\/j.snb.2017.09.128","article-title":"Effect of spacer length on the performance of peptide-based electrochemical biosensors for protease detection","volume":"255","author":"Gonz\u00e1lez-Fern\u00e1ndez","year":"2018","journal-title":"Sens. Actuators, B Chem."},{"key":"10.1016\/j.bios.2024.117022_bib16","doi-asserted-by":"crossref","first-page":"3032","DOI":"10.1021\/acssensors.3c00523","article-title":"Engineering a point-of-care paper-microfluidic electrochemical device applied to the multiplexed quantitative detection of biomarkers in sputum","volume":"8","author":"Guti\u00e9rrez-Capit\u00e1n","year":"2023","journal-title":"ACS Sens."},{"key":"10.1016\/j.bios.2024.117022_bib17","doi-asserted-by":"crossref","first-page":"329","DOI":"10.7861\/clinmedicine.17-4-329","article-title":"When laboratory tests can mislead even when they appear plausible","volume":"17","author":"Ismail","year":"2017","journal-title":"Clin. Med."},{"key":"10.1016\/j.bios.2024.117022_bib18","doi-asserted-by":"crossref","first-page":"1175","DOI":"10.1002\/anie.201005607","article-title":"Attomolar detection of a cancer biomarker protein in serum by surface plasmon resonance using superparamagnetic particle labels","volume":"50","author":"Krishnan","year":"2011","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.bios.2024.117022_bib19","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/j.snb.2017.02.052","article-title":"Microfluidic electrochemical devices for pollution analysis\u2013A review","volume":"246","author":"Kudr","year":"2017","journal-title":"Sens. Actuators, B Chem."},{"key":"10.1016\/j.bios.2024.117022_bib20","doi-asserted-by":"crossref","first-page":"6875","DOI":"10.3390\/ma15196875","article-title":"Gold-nanoparticle-coated magnetic beads for ALP-enzyme-based electrochemical immunosensing in human plasma","volume":"15","author":"Lee","year":"2022","journal-title":"Materials"},{"key":"10.1016\/j.bios.2024.117022_bib21","article-title":"Leprosy: treatment, prevention, immune response and gene function","volume":"15","author":"Li","year":"2024","journal-title":"Front. Immunol."},{"key":"10.1016\/j.bios.2024.117022_bib22","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3389\/fmicb.2020.00429","article-title":"Biotechnological and immunological platforms based on PGL-I carbohydrate-like peptide of Mycobacterium leprae for antibodies detection among leprosy clinical forms","volume":"11","author":"Lima","year":"2020","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.bios.2024.117022_bib23","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2020.00429","article-title":"Biotechnological and immunological platforms based on PGL-I carbohydrate-like peptide of Mycobacterium leprae for antibodies detection among leprosy clinical forms","volume":"11","author":"Lima","year":"2020","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.bios.2024.117022_bib24","doi-asserted-by":"crossref","first-page":"3355","DOI":"10.1590\/1413-81232020259.17812020","article-title":"Challenges and proposals for scaling up COVID-19 testing and diagnosis in Brazil","volume":"25","author":"Magno","year":"2020","journal-title":"Cienc. e Saude Coletiva."},{"key":"10.1016\/j.bios.2024.117022_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.jelechem.2021.115463","article-title":"Electrochemical immunoassay for serum parathyroid hormone using screen-printed carbon electrode and magnetic beads","volume":"895","author":"Malla","year":"2021","journal-title":"J. Electroanal. Chem."},{"key":"10.1016\/j.bios.2024.117022_bib26","doi-asserted-by":"crossref","first-page":"674","DOI":"10.1177\/1087057108321086","article-title":"A novel method for determination of the affinity of protein: protein interactions in homogeneous assays","volume":"13","author":"Newton","year":"2008","journal-title":"J. Biomol. Screen"},{"key":"10.1016\/j.bios.2024.117022_bib27","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1111\/j.1574-695X.2008.00491.x","article-title":"Classification of leprosy into multibacillary and paucibacillary groups: an analysis","volume":"55","author":"Parkash","year":"2009","journal-title":"FEMS Immunol. Med. Microbiol."},{"key":"10.1016\/j.bios.2024.117022_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2020.115831","article-title":"Microfluidics-integrated biosensing platforms as emergency tools for on-site field detection of foodborne pathogens","volume":"125","author":"Puiu","year":"2020","journal-title":"TrAC - Trends Anal. Chem."},{"key":"10.1016\/j.bios.2024.117022_bib29","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1097\/DAD.0000000000001476","article-title":"The importance of the biopsy technique in the diagnosis of histoid leprosy","volume":"42","author":"Rodrigues Daxbacher","year":"2020","journal-title":"Am. J. Dermatopathol."},{"key":"10.1016\/j.bios.2024.117022_bib30","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1016\/S0039-9140(01)00378-2","article-title":"Detection of zeptomolar concentrations of alkaline phosphatase based on a tyrosinase and horse-radish peroxidase bienzyme biosensor","volume":"54","author":"Ruan","year":"2001","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2024.117022_bib31","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1002\/tcr.201100034","article-title":"Nanomaterials\u2010based electrochemical immunosensors for proteins","volume":"12","author":"Rusling","year":"2012","journal-title":"Chem. Rec."},{"key":"10.1016\/j.bios.2024.117022_bib32","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/j.protcy.2017.04.035","article-title":"Electrochemical immunosensor for sensitive determination of TGF \u03b21 in urine","volume":"27","author":"S\u00e1nchez-Tirado","year":"2017","journal-title":"Proc. Technol."},{"key":"10.1016\/j.bios.2024.117022_bib33","doi-asserted-by":"crossref","first-page":"308","DOI":"10.1007\/s13206-020-4309-x","article-title":"Sensitivity improvement in electrochemical immunoassays using antibody immobilized magnetic nanoparticles with a clean ITO working electrode","volume":"14","author":"Song","year":"2020","journal-title":"BioChip J"},{"key":"10.1016\/j.bios.2024.117022_bib34","series-title":"Thermo Fisher, Dynabeads\u00ae MyOneTM Carboxylic Acid","year":"2020"},{"key":"10.1016\/j.bios.2024.117022_bib35","series-title":"Bioanalytical Requirements and Regulatory Guidelines for Immunoassays","author":"Vashist","year":"2018"},{"key":"10.1016\/j.bios.2024.117022_bib36","first-page":"87","volume":"1","year":"2018"},{"key":"10.1016\/j.bios.2024.117022_bib37","series-title":"Thirteenth Meeting of the WHO Strategic and Technical Advisory Group for Neglected Tropical Diseases","first-page":"27","year":"2020"},{"key":"10.1016\/j.bios.2024.117022_bib38","first-page":"421","article-title":"Global leprosy (Hansen disease) update, 2020: impact of COVID-19 on global leprosy control","volume":"96","year":"2020","journal-title":"Wkly. Epidemiol. Rec."},{"key":"10.1016\/j.bios.2024.117022_bib39","series-title":"Global Leprosy (Hansen Disease) Update, 2023: Elimination of Leprosy Disease Is Possible \u2013 Time to Act!","first-page":"2023","year":"2024"},{"key":"10.1016\/j.bios.2024.117022_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2019.111625","article-title":"Immunodiagnostic of leprosy exploiting a photoelectrochemical platform based on a recombinant peptide mimetic of a Mycobacterium leprae antigen","volume":"143","author":"Yotsumoto Neto","year":"2019","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2024.117022_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2019.111625","article-title":"Immunodiagnostic of leprosy exploiting a photoelectrochemical platform based on a recombinant peptide mimetic of a Mycobacterium leprae antigen","volume":"143","author":"Yotsumoto Neto","year":"2019","journal-title":"Biosens. Bioelectron."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566324010297?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566324010297?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T17:31:14Z","timestamp":1778779874000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566324010297"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3]]},"references-count":41,"alternative-id":["S0956566324010297"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2024.117022","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Electrochemical magneto-immunoassay based on Mycobacterium leprae mimotope for serological diagnosis of leprosy","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2024.117022","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117022"}}