{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T06:41:06Z","timestamp":1780814466475,"version":"3.54.1"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T00:00:00Z","timestamp":1759276800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100002855","name":"Ministry of Science and Technology of the People's Republic of China","doi-asserted-by":"publisher","award":["2021ZD0201300"],"award-info":[{"award-number":["2021ZD0201300"]}],"id":[{"id":"10.13039\/501100002855","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012659","name":"Foundation for Innovative Research Groups of the National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012659","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["12205229"],"award-info":[{"award-number":["12205229"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2025,10]]},"DOI":"10.1016\/j.bios.2025.117585","type":"journal-article","created":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T06:37:23Z","timestamp":1747204643000},"page":"117585","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"special_numbering":"C","title":["Bioelectronic nose for ultratrace odor detection via brain\u2013computer interface with olfactory bulb electrode arrays"],"prefix":"10.1016","volume":"285","author":[{"given":"Qian","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming","family":"Yi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2930-7770","authenticated-orcid":false,"given":"Junjie","family":"Jiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bios.2025.117585_bib1","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.cub.2019.11.006","article-title":"Aversive learning increases release probability of olfactory sensory neurons","volume":"30","author":"Bhattarai","year":"2020","journal-title":"Curr. Biol."},{"issue":"11","key":"10.1016\/j.bios.2025.117585_bib2","doi-asserted-by":"crossref","first-page":"19567","DOI":"10.1021\/acsnano.2c10240","article-title":"Machine learning-based rapid detection of volatile organic compounds in a graphene electronic nose","volume":"16","author":"Capman","year":"2022","journal-title":"ACS Nano"},{"issue":"9","key":"10.1016\/j.bios.2025.117585_bib3","doi-asserted-by":"crossref","first-page":"792","DOI":"10.1038\/s41565-020-0723-4","article-title":"Engineering synthetic breath biomarkers for respiratory disease","volume":"15","author":"Chan","year":"2020","journal-title":"Nat. Nanotechnol."},{"issue":"6","key":"10.1016\/j.bios.2025.117585_bib4","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1016\/j.neuron.2017.08.030","article-title":"A fully automated approach to spike sorting","volume":"95","author":"Chung","year":"2017","journal-title":"Neuron"},{"issue":"1","key":"10.1016\/j.bios.2025.117585_bib5","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.aca.2009.12.008","article-title":"Integrated explosive preconcentrator and electrochemical detection system for 2, 4, 6-Trinitrotoluene (TNT) vapor","volume":"661","author":"Cizek","year":"2010","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.bios.2025.117585_bib6","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2024.136409","article-title":"Facile e-Nose based on single antenna and graphene oxide for sensing volatile organic compound gases with ultrahigh selectivity and accuracy","volume":"419","author":"Dang","year":"2024","journal-title":"Sensor. Actuator. B Chem."},{"issue":"3","key":"10.1016\/j.bios.2025.117585_bib7","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1083\/jcb.201008163","article-title":"The cell biology of smell","volume":"191","author":"DeMaria","year":"2010","journal-title":"JCB (J. Cell Biol.)"},{"issue":"45","key":"10.1016\/j.bios.2025.117585_bib8","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.adp1764","article-title":"High-speed odor sensing using miniaturized electronic nose","volume":"10","author":"Dennler","year":"2024","journal-title":"Sci. Adv."},{"issue":"29","key":"10.1016\/j.bios.2025.117585_bib9","article-title":"Long-term flexible neural interface for synchronous recording of cross-regional sensory processing along the olfactory pathway","volume":"19","author":"Duan","year":"2023","journal-title":"Small"},{"issue":"1","key":"10.1016\/j.bios.2025.117585_bib10","doi-asserted-by":"crossref","first-page":"5572","DOI":"10.1038\/s41467-024-49897-4","article-title":"Acquisition of non-olfactory encoding improves odour discrimination in olfactory cortex","volume":"15","author":"Federman","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bios.2025.117585_bib11","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1016\/j.bios.2017.08.055","article-title":"In vivo bioelectronic nose using transgenic mice for specific odor detection","volume":"102","author":"Gao","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117585_bib12","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1016\/j.snb.2015.11.010","article-title":"Multi-odor discrimination by a novel bio-hybrid sensing preserving rat's intact smell perception in vivo","volume":"225","author":"Guo","year":"2016","journal-title":"Sensor. Actuator. B Chem."},{"issue":"1","key":"10.1016\/j.bios.2025.117585_bib13","doi-asserted-by":"crossref","first-page":"6415","DOI":"10.1038\/s41467-024-50563-y","article-title":"Flexible neural population dynamics govern the speed and stability of sensory encoding in mouse visual cortex","volume":"15","author":"Horrocks","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bios.2025.117585_bib14","first-page":"1","article-title":"Single-neuron representations of odours in the human brain","author":"Kehl","year":"2024","journal-title":"Nature"},{"issue":"5","key":"10.1016\/j.bios.2025.117585_bib15","doi-asserted-by":"crossref","first-page":"7080","DOI":"10.1021\/acsnano.1c10827","article-title":"Sensors for volatile organic compounds","volume":"16","author":"Khatib","year":"2022","journal-title":"ACS Nano"},{"issue":"1","key":"10.1016\/j.bios.2025.117585_bib16","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0021-9673(00)89207-9","article-title":"Vapor pressure of 2, 4, 6-Trinitrotoluene by a gas chromatographic headspace technique","volume":"133","author":"Leggett","year":"1977","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.bios.2025.117585_bib17","article-title":"The spiking output of the mouse olfactory bulb encodes large-scale temporal features of natural odor environments","author":"Lewis","year":"2024","journal-title":"bioRxiv"},{"key":"10.1016\/j.bios.2025.117585_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.chemosphere.2019.125731","article-title":"Hazardous volatile organic compounds in ambient air of China","volume":"246","author":"Lyu","year":"2020","journal-title":"Chemosphere"},{"issue":"5","key":"10.1016\/j.bios.2025.117585_bib19","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.1016\/j.cub.2024.01.060","article-title":"Event-specific and persistent representations for contextual states in orbitofrontal neurons","volume":"34","author":"Ma","year":"2024","journal-title":"Curr. Biol."},{"key":"10.1016\/j.bios.2025.117585_bib20","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2019.127456","article-title":"High sensitivity and ultra-low detection limit of chlorine gas sensor based on In2O3 nanosheets by a simple template method","volume":"305","author":"Ma","year":"2020","journal-title":"Sensor. Actuator. B Chem."},{"issue":"10","key":"10.1016\/j.bios.2025.117585_bib21","doi-asserted-by":"crossref","first-page":"1592","DOI":"10.1016\/j.cub.2019.03.065","article-title":"Local and global influences of visual spatial selection and locomotion in mouse primary visual cortex","volume":"29","author":"McBride","year":"2019","journal-title":"Curr. Biol."},{"issue":"1","key":"10.1016\/j.bios.2025.117585_bib22","doi-asserted-by":"crossref","first-page":"112","DOI":"10.1021\/acsnano.6b04930","article-title":"Diagnosis and classification of 17 diseases from 1404 subjects via pattern analysis of exhaled molecules","volume":"11","author":"Nakhleh","year":"2017","journal-title":"ACS Nano"},{"key":"10.1016\/j.bios.2025.117585_bib23","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.84604","article-title":"A stable, distributed code for cue value in mouse cortex during reward learning","volume":"12","author":"Ottenheimer","year":"2023","journal-title":"Elife"},{"issue":"12","key":"10.1016\/j.bios.2025.117585_bib24","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abf9153","article-title":"Three-dimensional, multifunctional neural interfaces for cortical spheroids and engineered assembloids","volume":"7","author":"Park","year":"2021","journal-title":"Sci. Adv."},{"key":"10.1016\/j.bios.2025.117585_bib25","series-title":"The Rat Brain in Stereotaxic Coordinates","author":"Paxinos","year":"2006"},{"issue":"2","key":"10.1016\/j.bios.2025.117585_bib26","doi-asserted-by":"crossref","first-page":"411","DOI":"10.1016\/j.neuron.2015.06.033","article-title":"How can single sensory neurons predict behavior?","volume":"87","author":"Pitkow","year":"2015","journal-title":"Neuron"},{"key":"10.1016\/j.bios.2025.117585_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2021.113664","article-title":"Sensitive and robust chemical detection using an olfactory brain-computer interface","volume":"195","author":"Shor","year":"2022","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117585_bib28","first-page":"4676","article-title":"Agency for toxic substances and disease registry","volume":"500","author":"Sites","year":"2002","journal-title":"Occup. Saf. Health"},{"issue":"2","key":"10.1016\/j.bios.2025.117585_bib29","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1016\/S0896-6273(02)00644-X","article-title":"Spatio-temporal dynamics of odor representations in the mammalian olfactory bulb","volume":"34","author":"Spors","year":"2002","journal-title":"Neuron"},{"issue":"1","key":"10.1016\/j.bios.2025.117585_bib30","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.cell.2009.09.015","article-title":"Olfactory perception: receptors, cells, and circuits","volume":"139","author":"Su","year":"2009","journal-title":"Cell"},{"issue":"33","key":"10.1016\/j.bios.2025.117585_bib31","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202302333","article-title":"An ultraflexible electrode array for large-scale chronic recording in the nonhuman primate brain","volume":"10","author":"Tian","year":"2023","journal-title":"Adv. Sci."},{"key":"10.1016\/j.bios.2025.117585_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2021.116330","article-title":"Bio-inspired approaches for explosives detection","volume":"142","author":"Wasilewski","year":"2021","journal-title":"TrAC, Trends Anal. Chem."},{"issue":"4","key":"10.1016\/j.bios.2025.117585_bib33","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1513\/pats.201001-008SM","article-title":"Chlorine gas inhalation: human clinical evidence of toxicity and experience in animal models","volume":"7","author":"White","year":"2010","journal-title":"Proc. Am. Thorac. Soc."},{"issue":"2","key":"10.1016\/j.bios.2025.117585_bib34","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0298448","article-title":"The behavioral sensitivity of mice to acyclic, monocyclic, and bicyclic monoterpenes","volume":"19","author":"Williams","year":"2024","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.bios.2025.117585_bib35","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0149-7634(03)00050-2","article-title":"Olfactory perceptual learning: the critical role of memory in odor discrimination","volume":"27","author":"Wilson","year":"2003","journal-title":"Neurosci. Biobehav. Rev."},{"issue":"1","key":"10.1016\/j.bios.2025.117585_bib36","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1016\/j.neuron.2012.01.032","article-title":"Effects of long-term visual experience on responses of distinct classes of single units in inferior temporal cortex","volume":"74","author":"Woloszyn","year":"2012","journal-title":"Neuron"},{"issue":"13","key":"10.1016\/j.bios.2025.117585_bib37","doi-asserted-by":"crossref","first-page":"7715","DOI":"10.1073\/pnas.95.13.7715","article-title":"Dynamic mapping at the laminar level of odor-elicited responses in rat olfactory bulb by functional MRI","volume":"95","author":"Yang","year":"1998","journal-title":"Proc. Natl. Acad. Sci."},{"issue":"1","key":"10.1016\/j.bios.2025.117585_bib38","doi-asserted-by":"crossref","first-page":"3495","DOI":"10.1038\/s41467-023-39213-x","article-title":"A chemiresistive-potentiometric multivariate sensor for discriminative gas detection","volume":"14","author":"Zhang","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bios.2025.117585_bib39","doi-asserted-by":"crossref","first-page":"694","DOI":"10.1016\/j.bios.2014.09.102","article-title":"Detection and classification of natural odors with an in vivo bioelectronic nose","volume":"67","author":"Zhuang","year":"2015","journal-title":"Biosens. Bioelectron."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566325004592?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566325004592?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,3]],"date-time":"2025-06-03T23:41:17Z","timestamp":1748994077000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566325004592"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10]]},"references-count":39,"alternative-id":["S0956566325004592"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2025.117585","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2025,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Bioelectronic nose for ultratrace odor detection via brain\u2013computer interface with olfactory bulb electrode arrays","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2025.117585","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117585"}}