{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T20:10:48Z","timestamp":1769890248112,"version":"3.49.0"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100006366","name":"Minist\u00e9rio da Educa\u00e7\u00e3o","doi-asserted-by":"publisher","award":["RS-2024-00449792"],"award-info":[{"award-number":["RS-2024-00449792"]}],"id":[{"id":"10.13039\/501100006366","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006366","name":"Minist\u00e9rio da Educa\u00e7\u00e3o","doi-asserted-by":"publisher","award":["RS-2023-00275869"],"award-info":[{"award-number":["RS-2023-00275869"]}],"id":[{"id":"10.13039\/501100006366","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003715","name":"Korea Research Institute of Bioscience and Biotechnology","doi-asserted-by":"publisher","award":["KGM1032511"],"award-info":[{"award-number":["KGM1032511"]}],"id":[{"id":"10.13039\/501100003715","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003715","name":"Korea Research Institute of Bioscience and Biotechnology","doi-asserted-by":"publisher","award":["KGM1322511"],"award-info":[{"award-number":["KGM1322511"]}],"id":[{"id":"10.13039\/501100003715","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003654","name":"Korea Environmental Industry and Technology Institute","doi-asserted-by":"publisher","award":["2021003370003"],"award-info":[{"award-number":["2021003370003"]}],"id":[{"id":"10.13039\/501100003654","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","award":["RS-2024-00432287"],"award-info":[{"award-number":["RS-2024-00432287"]}],"id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003052","name":"Ministry of Trade, Industry and Energy","doi-asserted-by":"publisher","award":["RS-2024-00403563"],"award-info":[{"award-number":["RS-2024-00403563"]}],"id":[{"id":"10.13039\/501100003052","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014188","name":"Ministry of Science and ICT, South Korea","doi-asserted-by":"publisher","award":["RS-2025-00554718"],"award-info":[{"award-number":["RS-2025-00554718"]}],"id":[{"id":"10.13039\/501100014188","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014189","name":"Korea Institute of Planning and Evaluation for Technology in Food, Agriculture and Forestry","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014189","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001321","name":"National Research Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001321","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003624","name":"Ministry of Agriculture, Food and Rural Affairs","doi-asserted-by":"publisher","award":["RS-2024-00399940"],"award-info":[{"award-number":["RS-2024-00399940"]}],"id":[{"id":"10.13039\/501100003624","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003662","name":"Korea Evaluation Institute of Industrial Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003662","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.bios.2025.117762","type":"journal-article","created":{"date-parts":[[2025,7,7]],"date-time":"2025-07-07T02:03:36Z","timestamp":1751853816000},"page":"117762","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Hemagglutinin docking analysis-based visual detection of antiviral therapeutic efficacy of umifenovir against influenza virus"],"prefix":"10.1016","volume":"287","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7204-8527","authenticated-orcid":false,"given":"Jinyoung","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7953-0914","authenticated-orcid":false,"given":"Jong-Woo","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hyun-Ouk","family":"Kim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2201-5553","authenticated-orcid":false,"given":"Joowon","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eunji","family":"Jeong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaewon","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Geunseon","family":"Park","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Minjoo","family":"Yeom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daesub","family":"Song","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2793-3700","authenticated-orcid":false,"given":"Eun-Kyung","family":"Lim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4990-0523","authenticated-orcid":false,"given":"Seungjoo","family":"Haam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4 Pt B","key":"10.1016\/j.bios.2025.117762_bib1","doi-asserted-by":"crossref","first-page":"603","DOI":"10.1177\/135965350701200S04.1","volume":"12","author":"Aoki","year":"2007","journal-title":"Antivir. Ther."},{"issue":"10107","key":"10.1016\/j.bios.2025.117762_bib2","doi-asserted-by":"crossref","first-page":"2099","DOI":"10.1016\/S0140-6736(17)31450-2","volume":"390","author":"Baud","year":"2017","journal-title":"Lancet"},{"issue":"10","key":"10.1016\/j.bios.2025.117762_bib3","doi-asserted-by":"crossref","first-page":"997","DOI":"10.2174\/092986708784049658","volume":"15","author":"Boriskin","year":"2008","journal-title":"Curr. Med. Chem."},{"issue":"6","key":"10.1016\/j.bios.2025.117762_bib4","doi-asserted-by":"crossref","first-page":"966","DOI":"10.3201\/eid1506.081357","volume":"15","author":"Cheng","year":"2009","journal-title":"Emerg. Infect. Dis."},{"issue":"8","key":"10.1016\/j.bios.2025.117762_bib5","doi-asserted-by":"crossref","first-page":"3891","DOI":"10.1021\/acs.jcim.1c00203","volume":"61","author":"Eberhardt","year":"2021","journal-title":"J. Chem. Inf. Model."},{"issue":"9","key":"10.1016\/j.bios.2025.117762_bib6","doi-asserted-by":"crossref","first-page":"2282","DOI":"10.1021\/acssensors.9b00697","volume":"4","author":"Eom","year":"2019","journal-title":"ACS Sens."},{"issue":"3","key":"10.1016\/j.bios.2025.117762_bib7","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1021\/acsabm.8b00807","volume":"2","author":"Eom","year":"2019","journal-title":"ACS Appl. Bio Mater."},{"issue":"1\u20132","key":"10.1016\/j.bios.2025.117762_bib8","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.virusres.2004.02.034","volume":"103","author":"Gubareva","year":"2004","journal-title":"Virus Res."},{"issue":"1","key":"10.1016\/j.bios.2025.117762_bib9","volume":"8","author":"Hwang","year":"2018","journal-title":"Sci. Rep."},{"issue":"2","key":"10.1016\/j.bios.2025.117762_bib10","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1073\/pnas.1617020114","volume":"114","author":"Kadam","year":"2017","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1","key":"10.1016\/j.bios.2025.117762_bib11","volume":"18","author":"Kim","year":"2020","journal-title":"J. Nanobiotechnol."},{"issue":"47","key":"10.1016\/j.bios.2025.117762_bib12","volume":"33","author":"Kim","year":"2021","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bios.2025.117762_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2021.113324","volume":"187","author":"Kim","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117762_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2022.114143","volume":"207","author":"Kim","year":"2022","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117762_bib15","author":"Kim","year":"2023","journal-title":"Small"},{"issue":"5","key":"10.1016\/j.bios.2025.117762_bib16","first-page":"4","volume":"51","author":"Leneva","year":"2006","journal-title":"Vopr. Virusol."},{"issue":"4","key":"10.1016\/j.bios.2025.117762_bib17","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1002\/jmv.25358","volume":"91","author":"Leneva","year":"2019","journal-title":"J. Med. Virol."},{"issue":"8","key":"10.1016\/j.bios.2025.117762_bib18","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1038\/aps.2013.54","volume":"34","author":"Liu","year":"2013","journal-title":"Acta Pharmacol. Sin."},{"issue":"22","key":"10.1016\/j.bios.2025.117762_bib19","doi-asserted-by":"crossref","DOI":"10.1128\/JVI.78.22.12665-12667.2004","volume":"78","author":"Matrosovich","year":"2004","journal-title":"J. Virol."},{"issue":"9","key":"10.1016\/j.bios.2025.117762_bib20","doi-asserted-by":"crossref","first-page":"1254","DOI":"10.1086\/598989","volume":"48","author":"Poland","year":"2009","journal-title":"Clin. Infect. Dis."},{"issue":"9","key":"10.1016\/j.bios.2025.117762_bib21","doi-asserted-by":"crossref","first-page":"5386","DOI":"10.1128\/JVI.00151-12","volume":"86","author":"Seibert","year":"2012","journal-title":"J. Virol."},{"issue":"2","key":"10.1016\/j.bios.2025.117762_bib22","doi-asserted-by":"crossref","first-page":"308","DOI":"10.3201\/eid1802.111466","volume":"18","author":"Storms","year":"2012","journal-title":"Emerg. Infect. Dis."},{"issue":"2","key":"10.1016\/j.bios.2025.117762_bib23","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1002\/jcc.21334","volume":"31","author":"Trott","year":"2010","journal-title":"J. Comput. Chem."},{"issue":"1","key":"10.1016\/j.bios.2025.117762_bib24","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1016\/j.antiviral.2010.04.002","volume":"87","author":"Wang","year":"2010","journal-title":"Antivir. Res."},{"key":"10.1016\/j.bios.2025.117762_bib25","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1016\/j.biopha.2017.04.091","volume":"91","author":"Wang","year":"2017","journal-title":"Biomed. Pharmacother."},{"issue":"1","key":"10.1016\/j.bios.2025.117762_bib26","volume":"6","author":"Wang","year":"2020","journal-title":"Cell Discov."},{"issue":"1","key":"10.1016\/j.bios.2025.117762_bib27","doi-asserted-by":"crossref","first-page":"6089","DOI":"10.1038\/s41467-020-19947-8","volume":"11","author":"Wang","year":"2020","journal-title":"Nat. Commun."},{"issue":"10","key":"10.1016\/j.bios.2025.117762_bib28","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1001145","volume":"6","author":"Ye","year":"2010","journal-title":"PLoS Pathog."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566325006384?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566325006384?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T04:34:57Z","timestamp":1769834097000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566325006384"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":28,"alternative-id":["S0956566325006384"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2025.117762","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Hemagglutinin docking analysis-based visual detection of antiviral therapeutic efficacy of umifenovir against influenza virus","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2025.117762","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"117762"}}