{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T18:38:59Z","timestamp":1793385539141,"version":"4.5.0"},"reference-count":106,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T00:00:00Z","timestamp":1761955200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100012905","name":"Department of Science and Technology of Shandong Province","doi-asserted-by":"publisher","award":["2024TSGC0378"],"award-info":[{"award-number":["2024TSGC0378"]}],"id":[{"id":"10.13039\/100012905","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010041","name":"Tianjin Municipal Science and Technology Committee","doi-asserted-by":"publisher","award":["25JCLMJC00050"],"award-info":[{"award-number":["25JCLMJC00050"]}],"id":[{"id":"10.13039\/501100010041","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010041","name":"Tianjin Municipal Science and Technology Committee","doi-asserted-by":"publisher","award":["23JCJQJC00090"],"award-info":[{"award-number":["23JCJQJC00090"]}],"id":[{"id":"10.13039\/501100010041","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010041","name":"Tianjin Municipal Science and Technology Committee","doi-asserted-by":"publisher","award":["22YFZCSN00070"],"award-info":[{"award-number":["22YFZCSN00070"]}],"id":[{"id":"10.13039\/501100010041","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010041","name":"Tianjin Municipal Science and Technology Committee","doi-asserted-by":"publisher","award":["19JCYBJC27800"],"award-info":[{"award-number":["19JCYBJC27800"]}],"id":[{"id":"10.13039\/501100010041","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32372415"],"award-info":[{"award-number":["32372415"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32072309"],"award-info":[{"award-number":["32072309"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2025,11]]},"DOI":"10.1016\/j.bios.2025.117786","type":"journal-article","created":{"date-parts":[[2025,7,15]],"date-time":"2025-07-15T17:00:17Z","timestamp":1752598817000},"page":"117786","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":42,"special_numbering":"C","title":["CRISPR-based one-pot detection: A game-changer in nucleic acid analysis"],"prefix":"10.1016","volume":"288","author":[{"given":"Xinyue","family":"Li","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jincan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roumeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongwei","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Myunghee","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingjie","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weipan","family":"Peng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuli","family":"Man","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhixian","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8479-2663","authenticated-orcid":false,"given":"Long","family":"Ma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bios.2025.117786_bib1","doi-asserted-by":"crossref","DOI":"10.1126\/science.aaf5573","volume":"353","author":"Abudayyeh","year":"2016","journal-title":"Science"},{"key":"10.1016\/j.bios.2025.117786_bib2","doi-asserted-by":"crossref","first-page":"938","DOI":"10.1039\/D2LC00852A","volume":"23","author":"Avaro","year":"2023","journal-title":"Lab Chip"},{"key":"10.1016\/j.bios.2025.117786_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2024.116866","volume":"267","author":"Cao","year":"2025","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2024.116051","volume":"250","author":"Changtor","year":"2024","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib5","volume":"1246","author":"Chen","year":"2023","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.bios.2025.117786_bib6","doi-asserted-by":"crossref","first-page":"436","DOI":"10.1126\/science.aar6245","volume":"360","author":"Chen","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.bios.2025.117786_bib7","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.tibtech.2024.07.007","volume":"43","author":"Chen","year":"2025","journal-title":"Trends Biotechnol."},{"key":"10.1016\/j.bios.2025.117786_bib8","volume":"95","author":"Chen","year":"2023","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.bios.2025.117786_bib9","first-page":"3145","volume":"96","author":"Chen","year":"2024","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2025.117786_bib10","doi-asserted-by":"crossref","first-page":"9724","DOI":"10.1021\/acs.analchem.2c01193","volume":"94","author":"Chen","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2025.117786_bib11","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.tibtech.2022.07.015","article-title":"Microfluidics: the propellant of CRISPR-Based nucleic acid detection","volume":"41","author":"Chen","year":"2023","journal-title":"Trends Biotechnol."},{"key":"10.1016\/j.bios.2025.117786_bib12","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.1038\/s41467-025-56516-3","volume":"16","author":"Cheng","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bios.2025.117786_bib13","volume":"1252","author":"Deng","year":"2023","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.bios.2025.117786_bib14","doi-asserted-by":"crossref","first-page":"97","DOI":"10.1016\/j.jare.2024.07.027","volume":"72","author":"Ding","year":"2024","journal-title":"J. Adv. Res."},{"key":"10.1016\/j.bios.2025.117786_bib15","doi-asserted-by":"crossref","first-page":"5773","DOI":"10.3390\/ijms25115773","volume":"25","author":"Dong","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bios.2025.117786_bib16","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/nature19802","volume":"538","author":"East-Seletsky","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.bios.2025.117786_bib17","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2024.116740","volume":"267","author":"Fu","year":"2025","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2021.113682","volume":"195","author":"Fu","year":"2022","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib19","doi-asserted-by":"crossref","first-page":"837","DOI":"10.1021\/acssynbio.3c00655","volume":"13","author":"Ghouneimy","year":"2024","journal-title":"ACS Synth. Biol."},{"key":"10.1016\/j.bios.2025.117786_bib20","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1126\/science.aam9321","volume":"356","author":"Gootenberg","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.bios.2025.117786_bib21","doi-asserted-by":"crossref","first-page":"11195","DOI":"10.1021\/acs.jafc.4c01028","volume":"72","author":"Han","year":"2024","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bios.2025.117786_bib22","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1126\/science.aav4294","volume":"362","author":"Harrington","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.bios.2025.117786_bib23","doi-asserted-by":"crossref","first-page":"3957","DOI":"10.1093\/nar\/25.19.3957","volume":"25","author":"Henke","year":"1997","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bios.2025.117786_bib24","doi-asserted-by":"crossref","first-page":"658","DOI":"10.1021\/acs.analchem.4c05026","volume":"97","author":"Hu","year":"2025","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2025.117786_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2022.113994","volume":"202","author":"Hu","year":"2022","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib26","doi-asserted-by":"crossref","first-page":"1381","DOI":"10.1021\/acs.jafc.2c06549","volume":"71","author":"Hu","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bios.2025.117786_bib27","volume":"62","author":"Hu","year":"2023","journal-title":"Angew Chem. Int. Ed. Engl."},{"key":"10.1016\/j.bios.2025.117786_bib28","volume":"119","author":"Hu","year":"2022","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.bios.2025.117786_bib29","volume":"3","author":"Huang","year":"2024","journal-title":"Imeta"},{"key":"10.1016\/j.bios.2025.117786_bib30","doi-asserted-by":"crossref","first-page":"3026","DOI":"10.1021\/acs.analchem.4c06066","volume":"97","author":"Huang","year":"2025","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2025.117786_bib31","doi-asserted-by":"crossref","first-page":"956","DOI":"10.3390\/bios12110956","volume":"12","author":"Iakovlev","year":"2022","journal-title":"Biosensors"},{"key":"10.1016\/j.bios.2025.117786_bib32","doi-asserted-by":"crossref","first-page":"5429","DOI":"10.1128\/jb.169.12.5429-5433.1987","volume":"169","author":"Ishino","year":"1987","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.bios.2025.117786_bib33","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1046\/j.1365-2958.2002.02839.x","volume":"43","author":"Jansen","year":"2002","journal-title":"Mol. Microbiol."},{"key":"10.1016\/j.bios.2025.117786_bib34","doi-asserted-by":"crossref","first-page":"1465","DOI":"10.1111\/pbi.14051","volume":"21","author":"Jiao","year":"2023","journal-title":"Plant Biotechnol. J."},{"key":"10.1016\/j.bios.2025.117786_bib35","doi-asserted-by":"crossref","first-page":"6271","DOI":"10.1038\/s41467-024-50588-3","volume":"15","author":"Lee","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bios.2025.117786_bib36","doi-asserted-by":"crossref","first-page":"10522","DOI":"10.1021\/acs.analchem.2c05032","volume":"95","author":"Li","year":"2023","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2025.117786_bib37","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1038\/s41421-018-0028-z","volume":"4","author":"Li","year":"2018","journal-title":"Cell Discov"},{"key":"10.1016\/j.bios.2025.117786_bib38","doi-asserted-by":"crossref","first-page":"13577","DOI":"10.1021\/acs.jafc.3c03619","volume":"71","author":"Li","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bios.2025.117786_bib39","volume":"15","author":"Li","year":"2024","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.bios.2025.117786_bib40","volume":"192","author":"Li","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib41","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2023.115609","volume":"239","author":"Lin","year":"2023","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib42","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2023.125616","volume":"271","author":"Lin","year":"2024","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2025.117786_bib43","doi-asserted-by":"crossref","first-page":"8277","DOI":"10.1021\/acs.analchem.2c00616","volume":"94","author":"Lin","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2025.117786_bib44","doi-asserted-by":"crossref","first-page":"5883","DOI":"10.1021\/acs.analchem.2c00067","volume":"94","author":"Liu","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2025.117786_bib45","author":"Liu","year":"2024","journal-title":"Small Methods e2400030"},{"key":"10.1016\/j.bios.2025.117786_bib46","doi-asserted-by":"crossref","first-page":"2960","DOI":"10.1080\/10408398.2022.2128300","volume":"64","author":"Liu","year":"2024","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.bios.2025.117786_bib47","volume":"e202401486","author":"Liu","year":"2024","journal-title":"Angew Chem. Int. Ed. Engl."},{"key":"10.1016\/j.bios.2025.117786_bib48","doi-asserted-by":"crossref","first-page":"5014","DOI":"10.1038\/s41467-024-49414-7","volume":"15","author":"Liu","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bios.2025.117786_bib49","doi-asserted-by":"crossref","first-page":"286","DOI":"10.1038\/s41551-022-00861-x","volume":"6","author":"Lu","year":"2022","journal-title":"Nat. Biomed. Eng."},{"key":"10.1016\/j.bios.2025.117786_bib50","author":"Lv"},{"key":"10.1016\/j.bios.2025.117786_bib51","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.tibtech.2024.06.006","volume":"43","author":"Ma","year":"2025","journal-title":"Trends Biotechnol."},{"key":"10.1016\/j.bios.2025.117786_bib52","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2023.115830","volume":"246","author":"Madadelahi","year":"2024","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib53","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2118260119","volume":"119","author":"Mahas","year":"2022","journal-title":"Proc. Natl. Acad. Sci. U. S. A"},{"key":"10.1016\/j.bios.2025.117786_bib54","doi-asserted-by":"crossref","first-page":"722","DOI":"10.1038\/nrmicro3569","volume":"13","author":"Makarova","year":"2015","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.bios.2025.117786_bib55","doi-asserted-by":"crossref","first-page":"1555","DOI":"10.1021\/acssynbio.1c00617","volume":"11","author":"Malci","year":"2022","journal-title":"ACS Synth. Biol."},{"key":"10.1016\/j.bios.2025.117786_bib56","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.1039\/b820557b","volume":"39","author":"Mark","year":"2010","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.bios.2025.117786_bib57","doi-asserted-by":"crossref","first-page":"8823","DOI":"10.1021\/acs.jafc.3c06744","volume":"72","author":"Meng","year":"2024","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bios.2025.117786_bib58","volume":"4","author":"Nguyen","year":"2023","journal-title":"Cell Rep. Med."},{"key":"10.1016\/j.bios.2025.117786_bib59","volume":"2","author":"Ning","year":"2022","journal-title":"Cell Rep. Med."},{"key":"10.1016\/j.bios.2025.117786_bib60","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1089\/crispr.2022.0048","volume":"6","author":"Patchsung","year":"2023","journal-title":"CRISPR J."},{"key":"10.1016\/j.bios.2025.117786_bib61","volume":"62","author":"Peng","year":"2024","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.bios.2025.117786_bib62","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1186\/s12943-024-02218-1","volume":"24","author":"Peng","year":"2025","journal-title":"Mol. Cancer"},{"key":"10.1016\/j.bios.2025.117786_bib63","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1126\/science.341.6148.833","volume":"341","author":"Pennisi","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.bios.2025.117786_bib64","doi-asserted-by":"crossref","first-page":"1091","DOI":"10.7150\/thno.78872","volume":"13","author":"Pittman","year":"2023","journal-title":"Theranostics"},{"key":"10.1016\/j.bios.2025.117786_bib65","first-page":"1","volume":"64","author":"Qiao","year":"2023","journal-title":"Crit. Rev. Food Sci. Nutr."},{"key":"10.1016\/j.bios.2025.117786_bib66","volume":"233","author":"Qiu","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.bios.2025.117786_bib67","volume":"273","author":"Qureshi","year":"2025","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib68","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2024.342886","volume":"1318","author":"Ren","year":"2024","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.bios.2025.117786_bib69","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1038\/nature13118","volume":"507","author":"Sackmann","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.bios.2025.117786_bib70","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1038\/nbt.2842","volume":"32","author":"Sander","year":"2014","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.bios.2025.117786_bib71","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2024.116292","volume":"257","author":"Sen","year":"2024","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib72","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2023.115771","volume":"243","author":"Shang","year":"2024","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib73","volume":"63","author":"Shi","year":"2024","journal-title":"Angew Chem. Int. Ed. Engl."},{"key":"10.1016\/j.bios.2025.117786_bib74","doi-asserted-by":"crossref","first-page":"816","DOI":"10.1016\/j.molcel.2018.06.043","volume":"71","author":"Strohkendl","year":"2018","journal-title":"Mol. Cell"},{"key":"10.1016\/j.bios.2025.117786_bib75","volume":"12","author":"Sun","year":"2024","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.bios.2025.117786_bib76","volume":"96","author":"Tan","year":"2024","journal-title":"J. Med. Virol."},{"key":"10.1016\/j.bios.2025.117786_bib77","doi-asserted-by":"crossref","first-page":"5542","DOI":"10.1021\/acs.jafc.3c09621","volume":"72","author":"Tang","year":"2024","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bios.2025.117786_bib78","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1038\/s41589-023-01534-9","volume":"20","author":"Tong","year":"2024","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.bios.2025.117786_bib79","doi-asserted-by":"crossref","first-page":"657","DOI":"10.1021\/acscentsci.2c01467","volume":"9","author":"Van der Veer","year":"2023","journal-title":"ACS Cent. Sci."},{"key":"10.1016\/j.bios.2025.117786_bib80","doi-asserted-by":"crossref","first-page":"6490","DOI":"10.1021\/acs.jafc.2c08689","volume":"71","author":"Wang","year":"2023","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bios.2025.117786_bib81","volume":"374","author":"Wang","year":"2023","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.bios.2025.117786_bib82","volume":"172","author":"Wang","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib83","volume":"14","author":"Wang","year":"2023","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.bios.2025.117786_bib84","volume":"257","author":"Wang","year":"2024","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib85","doi-asserted-by":"crossref","first-page":"3142","DOI":"10.1016\/j.scib.2023.11.023","volume":"68","author":"Wang","year":"2023","journal-title":"Sci. Bull."},{"key":"10.1016\/j.bios.2025.117786_bib86","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2023.115920","volume":"247","author":"Watanabe","year":"2024","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib87","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1038\/nature05058","volume":"442","author":"Whitesides","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.bios.2025.117786_bib88","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2022.114885","volume":"220","author":"Xing","year":"2023","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib89","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2024.342702","volume":"1310","author":"Xu","year":"2024","journal-title":"Anal. Chim. Acta"},{"key":"10.1016\/j.bios.2025.117786_bib90","doi-asserted-by":"crossref","first-page":"1583","DOI":"10.1038\/s41551-023-01033-1","volume":"7","author":"Yan","year":"2023","journal-title":"Nat. Biomed. Eng."},{"key":"10.1016\/j.bios.2025.117786_bib91","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1039\/C5CS00649J","volume":"47","author":"Yang","year":"2018","journal-title":"Chem. Soc. Rev."},{"key":"10.1016\/j.bios.2025.117786_bib92","doi-asserted-by":"crossref","first-page":"5471","DOI":"10.1021\/acs.analchem.3c05545","volume":"96","author":"Yang","year":"2024","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2025.117786_bib93","doi-asserted-by":"crossref","first-page":"3511","DOI":"10.1021\/acssensors.3c02485","volume":"9","author":"Yao","year":"2024","journal-title":"ACS Sens."},{"key":"10.1016\/j.bios.2025.117786_bib94","author":"Yao","year":"2025","journal-title":"Adv. Sci. 2501269"},{"key":"10.1016\/j.bios.2025.117786_bib95","volume":"287","author":"Yu","year":"2025","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2025.117786_bib96","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2024.116196","volume":"253","author":"Zhang","year":"2024","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib97","volume":"219","author":"Zhang","year":"2023","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib98","volume":"274","author":"Zhang","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.bios.2025.117786_bib99","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2025.117212","volume":"274","author":"Zhang","year":"2025","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117786_bib100","doi-asserted-by":"crossref","first-page":"8257","DOI":"10.1021\/acs.jafc.4c00204","volume":"72","author":"Zhao","year":"2024","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.bios.2025.117786_bib101","doi-asserted-by":"crossref","first-page":"10795","DOI":"10.1093\/nar\/gkad748","volume":"51","author":"Zhao","year":"2023","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.bios.2025.117786_bib102","doi-asserted-by":"crossref","first-page":"12491","DOI":"10.1021\/acs.chemrev.5b00428","volume":"115","author":"Zhao","year":"2015","journal-title":"Chem. Rev."},{"key":"10.1016\/j.bios.2025.117786_bib103","doi-asserted-by":"crossref","first-page":"33505","DOI":"10.1021\/acsnano.4c10823","volume":"18","author":"Zhao","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.bios.2025.117786_bib104","volume":"18","author":"Zheng","year":"2022","journal-title":"Small"},{"key":"10.1016\/j.bios.2025.117786_bib105","volume":"21","author":"Zhou","year":"2025","journal-title":"Small"},{"key":"10.1016\/j.bios.2025.117786_bib106","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2023.115179","volume":"228","author":"Zhu","year":"2023","journal-title":"Biosens. Bioelectron."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566325006621?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566325006621?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:46:00Z","timestamp":1777596360000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566325006621"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11]]},"references-count":106,"alternative-id":["S0956566325006621"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2025.117786","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2025,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"CRISPR-based one-pot detection: A game-changer in nucleic acid analysis","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2025.117786","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"117786"}}