{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,3]],"date-time":"2026-11-03T03:48:42Z","timestamp":1793677722262,"version":"4.5.1"},"reference-count":81,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32102689"],"award-info":[{"award-number":["32102689"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012542","name":"Sichuan Province Science and Technology Support Program","doi-asserted-by":"publisher","award":["2024NSFSC2060"],"award-info":[{"award-number":["2024NSFSC2060"]}],"id":[{"id":"10.13039\/100012542","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.bios.2025.117896","type":"journal-article","created":{"date-parts":[[2025,8,18]],"date-time":"2025-08-18T21:44:33Z","timestamp":1755553473000},"page":"117896","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":8,"special_numbering":"C","title":["A bacteriophage protein-driven platform for rapid and precise diagnosis of bacterial pathogens from blood samples"],"prefix":"10.1016","volume":"289","author":[{"given":"Jinhuan","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijue","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xin","family":"Fan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuanfeng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1738-7857","authenticated-orcid":false,"given":"Yong","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongping","family":"Wan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2366-3360","authenticated-orcid":false,"given":"Xinghong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bios.2025.117896_bib1","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.3390\/s17081885","article-title":"Detection methodologies for pathogen and toxins: a review","volume":"17","author":"Alahi","year":"2017","journal-title":"Sensors"},{"key":"10.1016\/j.bios.2025.117896_bib2","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1093\/femsre\/fuaa001","article-title":"Antibiotic resistance: turning evolutionary principles into clinical reality","volume":"44","author":"Andersson","year":"2020","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.bios.2025.117896_bib3","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.cels.2015.08.013","article-title":"Engineering modular viral scaffolds for targeted bacterial population editing","volume":"1","author":"Ando","year":"2015","journal-title":"Cell Syst."},{"key":"10.1016\/j.bios.2025.117896_bib4","doi-asserted-by":"crossref","first-page":"E145","DOI":"10.1002\/adma.200904285","article-title":"Nanostructured Fe3O4\/swnt electrode: binder\u2010free and high\u2010rate li\u2010ion anode","volume":"22","author":"Ban","year":"2010","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bios.2025.117896_bib5","doi-asserted-by":"crossref","first-page":"105","DOI":"10.4103\/jfmpc.jfmpc_578_19","article-title":"Trends in FDA drug approvals over last 2 decades: an observational study","volume":"9","author":"Batta","year":"2020","journal-title":"J. Fam. Med. Prim. Care"},{"key":"10.1016\/j.bios.2025.117896_bib6","doi-asserted-by":"crossref","DOI":"10.1093\/femsle\/fnw002","article-title":"Host receptors for bacteriophage adsorption","volume":"363","author":"Bertozzi Silva","year":"2016","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.bios.2025.117896_bib7","doi-asserted-by":"crossref","first-page":"2312","DOI":"10.1021\/acs.jmedchem.0c01516","article-title":"A decade of FDA-Approved drugs (2010\u20132019): trends and future directions","volume":"64","author":"Brown","year":"2021","journal-title":"J. Med. Chem."},{"key":"10.1016\/j.bios.2025.117896_bib8","doi-asserted-by":"crossref","first-page":"783","DOI":"10.1128\/CMR.00003-14","article-title":"Emerging technologies for the clinical microbiology laboratory","volume":"27","author":"Buchan","year":"2014","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.bios.2025.117896_bib9","first-page":"1","article-title":"Antibiotics in the clinical pipeline as of December 2022","author":"Butler","year":"2023","journal-title":"J. Antibiot. (Tokyo)."},{"key":"10.1016\/j.bios.2025.117896_bib10","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1007\/s00253-016-7747-6","article-title":"Characterization of a novel cell wall binding domain-containing Staphylococcus aureus endolysin LysSA97","volume":"101","author":"Chang","year":"2017","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.bios.2025.117896_bib11","doi-asserted-by":"crossref","first-page":"9610","DOI":"10.1021\/acs.analchem.2c00682","article-title":"Engineering phage tail fiber protein as a wide-spectrum probe for Acinetobacter baumannii strains with a recognition rate of 100%","volume":"94","author":"Chen","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2025.117896_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2020.128562","article-title":"Development of an endolysin enzyme and its cell wall\u2013binding domain protein and their applications for biocontrol and rapid detection of Clostridium perfringens in food","volume":"345","author":"Cho","year":"2021","journal-title":"Food Chem."},{"key":"10.1016\/j.bios.2025.117896_bib13","doi-asserted-by":"crossref","DOI":"10.1111\/1541-4337.70124","article-title":"Phage\u2010derived proteins: advancing food safety through biocontrol and detection of foodborne pathogens","volume":"24","author":"Choi","year":"2025","journal-title":"Compr. Rev. Food Sci. Food Saf."},{"key":"10.1016\/j.bios.2025.117896_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2022.132917","article-title":"A microfluidic platform combined with bacteriophage receptor binding proteins for multiplex detection of Escherichia coli and Pseudomonas aeruginosa in blood","volume":"376","author":"Costa","year":"2023","journal-title":"Sensors Actuators B Chem."},{"key":"10.1016\/j.bios.2025.117896_bib15","doi-asserted-by":"crossref","DOI":"10.1093\/femspd\/ftac027","article-title":"Burden of bacterial bloodstream infections and recent advances for diagnosis","volume":"80","author":"Costa","year":"2022","journal-title":"Pathog. Dis."},{"key":"10.1016\/j.bios.2025.117896_bib16","doi-asserted-by":"crossref","DOI":"10.3389\/fmicb.2022.871855","article-title":"A phage receptor-binding protein as a promising tool for the detection of Escherichia coli in human specimens","volume":"13","author":"Costa","year":"2022","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.bios.2025.117896_bib17","doi-asserted-by":"crossref","first-page":"6260","DOI":"10.1038\/s41598-020-62533-7","article-title":"A novel flow cytometry assay based on bacteriophage-derived proteins for staphylococcus detection in blood","volume":"10","author":"Costa","year":"2020","journal-title":"Sci. Rep."},{"key":"10.1016\/j.bios.2025.117896_bib18","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1080\/07388551.2022.2071671","article-title":"Potential of bacteriophage proteins as recognition molecules for pathogen detection","volume":"43","author":"Costa","year":"2023","journal-title":"Crit. Rev. Biotechnol."},{"key":"10.1016\/j.bios.2025.117896_bib19","doi-asserted-by":"crossref","first-page":"494","DOI":"10.1038\/d41586-024-02601-4","article-title":"Five ways science is tackling the antibiotic resistance crisis","volume":"632","author":"Dance","year":"2024","journal-title":"Nature"},{"key":"10.1016\/j.bios.2025.117896_bib20","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1016\/j.tim.2018.08.006","article-title":"Molecular and evolutionary determinants of bacteriophage host range","volume":"27","author":"de Jonge","year":"2019","journal-title":"Trends Microbiol."},{"key":"10.1016\/j.bios.2025.117896_bib21","doi-asserted-by":"crossref","first-page":"2842","DOI":"10.1002\/ange.200462551","article-title":"Monodisperse magnetic single\u2010crystal ferrite microspheres","volume":"117","author":"Deng","year":"2005","journal-title":"Angew. Chemie"},{"key":"10.1016\/j.bios.2025.117896_bib22","doi-asserted-by":"crossref","DOI":"10.1128\/AEM.00277-17","article-title":"Modified bacteriophage S16 long tail fiber proteins for rapid and specific immobilization and detection of salmonella cells","volume":"83","author":"Denyes","year":"2017","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.bios.2025.117896_bib23","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1021\/acsinfecdis.0c00890","article-title":"Recent innovations in bacterial infection detection and treatment","volume":"7","author":"Deusenbery","year":"2021","journal-title":"ACS Infect. Dis."},{"key":"10.1016\/j.bios.2025.117896_bib24","doi-asserted-by":"crossref","first-page":"e441","DOI":"10.1097\/INF.0000000000004498","article-title":"Current perspectives on antigen testing in respiratory infections","volume":"43","author":"Dimopoulou","year":"2024","journal-title":"Pediatr. Infect. Dis. J."},{"key":"10.1016\/j.bios.2025.117896_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2022.112212","article-title":"Magnetic microbead enzyme-linked immunoassay based on phage encoded protein RBP 41-mediated for rapid and sensitive detection of salmonella in food matrices","volume":"163","author":"Ding","year":"2023","journal-title":"Food Res. Int."},{"key":"10.1016\/j.bios.2025.117896_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2023.125561","article-title":"An electrochemical biosensor based on phage-encoded protein RBP 41 for rapid and sensitive detection of salmonella","volume":"270","author":"Ding","year":"2024","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2025.117896_bib27","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2023.136724","article-title":"Quantum dot-labeled phage-encoded RBP 55 as a fluorescent nanoprobe for sensitive and specific detection of salmonella in food matrices","volume":"428","author":"Ding","year":"2023","journal-title":"Food Chem."},{"key":"10.1016\/j.bios.2025.117896_bib28","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1016\/j.copbio.2021.02.006","article-title":"Reprogramming bacteriophage host range: design principles and strategies for engineering receptor binding proteins","volume":"68","author":"Dunne","year":"2021","journal-title":"Curr. Opin. Biotechnol."},{"key":"10.1016\/j.bios.2025.117896_bib29","doi-asserted-by":"crossref","first-page":"1336","DOI":"10.1016\/j.celrep.2019.09.062","article-title":"Reprogramming bacteriophage host range through structure-guided design of chimeric receptor binding proteins","volume":"29","author":"Dunne","year":"2019","journal-title":"Cell Rep."},{"key":"10.1016\/j.bios.2025.117896_bib30","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.medmal.2018.12.004","article-title":"Limitations of diagnostic tests for bacterial infections","volume":"49","author":"Eldin","year":"2019","journal-title":"Med. Mal. Infect."},{"key":"10.1016\/j.bios.2025.117896_bib31","doi-asserted-by":"crossref","first-page":"574","DOI":"10.1038\/nrmicro3068","article-title":"Modern clinical microbiology: new challenges and solutions","volume":"11","author":"Fournier","year":"2013","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.bios.2025.117896_bib32","doi-asserted-by":"crossref","DOI":"10.1128\/cmr.00015-22","article-title":"The microbial etiology of community-acquired pneumonia in adults: from classical bacteriology to host transcriptional signatures","volume":"35","author":"Gadsby","year":"2022","journal-title":"Clin. Microbiol. Rev."},{"key":"10.1016\/j.bios.2025.117896_bib33","doi-asserted-by":"crossref","first-page":"2588","DOI":"10.1039\/C3NR05422E","article-title":"Ferromagnetic nanoparticles with peroxidase-like activity enhance the cleavage of biological macromolecules for biofilm elimination","volume":"6","author":"Gao","year":"2014","journal-title":"Nanoscale"},{"key":"10.1016\/j.bios.2025.117896_bib34","first-page":"180","article-title":"Approved antibacterial drugs in the last 10 years: from the bench to the clinic. Explor","volume":"1","author":"Garc\u00eda-Castro","year":"2023","journal-title":"Drug Sci."},{"key":"10.1016\/j.bios.2025.117896_bib35","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1007\/s00284-011-0018-y","article-title":"LysGH15B, the SH3b domain of staphylococcal phage endolysin LysGH15, retains high affinity to staphylococci","volume":"63","author":"Gu","year":"2011","journal-title":"Curr. Microbiol."},{"key":"10.1016\/j.bios.2025.117896_bib36","doi-asserted-by":"crossref","first-page":"111","DOI":"10.1128\/JCM.01144-10","article-title":"LysGH15, a novel bacteriophage lysin, protects a murine bacteremia model efficiently against lethal methicillin-resistant Staphylococcus aureus infection","volume":"49","author":"Gu","year":"2011","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.bios.2025.117896_bib37","series-title":"Open Forum Infectious Diseases","first-page":"ofz090","article-title":"Sustained circulating bacterial deoxyribonucleic acid is associated with complicated Staphylococcus aureus bacteremia","author":"Gutierrez","year":"2019"},{"key":"10.1016\/j.bios.2025.117896_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2023.115911","article-title":"Specific separation and sensitive detection of foodborne pathogens by phage-derived bacterial-binding protein-nano magnetic beads coupled with smartphone-assisted paper sensor","volume":"247","author":"Hong","year":"2024","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117896_bib39","doi-asserted-by":"crossref","DOI":"10.15252\/embr.202051034","article-title":"Antibiotic resistance and persistence\u2014Implications for human health and treatment perspectives","volume":"21","author":"Huemer","year":"2020","journal-title":"EMBO Rep."},{"key":"10.1016\/j.bios.2025.117896_bib40","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2021.112973","article-title":"Bacteriophage-based advanced bacterial detection: concept, mechanisms, and applications","volume":"177","author":"Hussain","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117896_bib41","doi-asserted-by":"crossref","first-page":"S81","DOI":"10.1086\/653053","article-title":"Microbial etiologies of hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia","volume":"51","author":"Jones","year":"2010","journal-title":"Clin. Infect. Dis."},{"key":"10.1016\/j.bios.2025.117896_bib42","doi-asserted-by":"crossref","first-page":"3255","DOI":"10.1128\/JCM.01045-09","article-title":"Differentiating culture samples representing coagulase-negative staphylococcal bacteremia from those representing contamination by use of time-to-positivity and quantitative blood culture methods","volume":"47","author":"Kassis","year":"2009","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.bios.2025.117896_bib43","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1038\/s41564-022-01089-w","article-title":"Metagenomics-enabled microbial surveillance","volume":"7","author":"Ko","year":"2022","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.bios.2025.117896_bib44","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1016\/j.bios.2017.05.010","article-title":"Lateral flow assay-based bacterial detection using engineered cell wall binding domains of a phage endolysin","volume":"96","author":"Kong","year":"2017","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117896_bib45","doi-asserted-by":"crossref","first-page":"1992","DOI":"10.1128\/AEM.02402-06","article-title":"Use of high-affinity cell wall-binding domains of bacteriophage endolysins for immobilization and separation of bacterial cells","volume":"73","author":"Kretzer","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.bios.2025.117896_bib46","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/j.copbio.2020.11.003","article-title":"Enhancing phage therapy through synthetic biology and genome engineering","volume":"68","author":"Lenneman","year":"2021","journal-title":"Curr. Opin. Biotechnol."},{"key":"10.1016\/j.bios.2025.117896_bib47","doi-asserted-by":"crossref","first-page":"1063","DOI":"10.1038\/s41551-020-00637-1","article-title":"Treatment of infarcted heart tissue via the capture and local delivery of circulating exosomes through antibody-conjugated magnetic nanoparticles","volume":"4","author":"Liu","year":"2020","journal-title":"Nat. Biomed. Eng."},{"key":"10.1016\/j.bios.2025.117896_bib48","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.1126\/science.1066869","article-title":"Rapid killing of Streptococcus pneumoniae with a bacteriophage cell wall hydrolase","volume":"294","author":"Loeffler","year":"2001","journal-title":"Science"},{"key":"10.1016\/j.bios.2025.117896_bib49","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.mib.2005.06.002","article-title":"Bacteriophage Endolysins\u2014Current state of research and applications","volume":"8","author":"Loessner","year":"2005","journal-title":"Curr. Opin. Microbiol."},{"key":"10.1016\/j.bios.2025.117896_bib50","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3001424","article-title":"Systematic exploration of Escherichia coli phage\u2013host interactions with the BASEL phage collection","volume":"19","author":"Maffei","year":"2021","journal-title":"PLoS Biol."},{"key":"10.1016\/j.bios.2025.117896_bib51","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1128\/JCM.02264-16","article-title":"Implementation of rapid molecular infectious disease diagnostics: the role of diagnostic and antimicrobial stewardship","volume":"55","author":"Messacar","year":"2017","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.bios.2025.117896_bib52","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1111\/j.1537-2995.2005.00668.x","article-title":"Basics of flow cytometry\u2013based sterility testing of platelet concentrates","volume":"46","author":"Mohr","year":"2006","journal-title":"Transfusion"},{"key":"10.1016\/j.bios.2025.117896_bib53","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1016\/S0140-6736(21)02724-0","article-title":"Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis","volume":"399","author":"Murray","year":"2022","journal-title":"Lancet"},{"key":"10.1016\/j.bios.2025.117896_bib54","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/s41579-024-01116-z","article-title":"Streptococcus pneumoniae epidemiology, pathogenesis and control","volume":"23","author":"Narciso","year":"2025","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.bios.2025.117896_bib55","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0266869","article-title":"Bacterial DNA load in Staphylococcus aureus bacteremia is significantly higher in intravascular infections","volume":"17","author":"Nieman","year":"2022","journal-title":"PLoS One"},{"key":"10.1016\/j.bios.2025.117896_bib56","doi-asserted-by":"crossref","first-page":"3077","DOI":"10.1021\/acsinfecdis.1c00366","article-title":"Exploitation of a klebsiella bacteriophage receptor-binding protein as a superior biorecognition molecule","volume":"7","author":"Nogueira","year":"2021","journal-title":"ACS Infect. Dis."},{"key":"10.1016\/j.bios.2025.117896_bib57","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1080\/07388551.2022.2095253","article-title":"Advanced diagnostic methods for identification of bacterial foodborne pathogens: contemporary and upcoming challenges","volume":"43","author":"Panwar","year":"2023","journal-title":"Crit. Rev. Biotechnol."},{"key":"10.1016\/j.bios.2025.117896_bib58","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1007\/s13206-018-2408-8","article-title":"Detection of bacillus cereus using bioluminescence assay with cell wall-binding domain conjugated magnetic nanoparticles","volume":"12","author":"Park","year":"2018","journal-title":"BioChip J."},{"key":"10.1016\/j.bios.2025.117896_bib59","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/s11908-021-00755-0","article-title":"New microbiological techniques for the diagnosis of bacterial infections and sepsis in ICU including point of care","volume":"23","author":"Peri","year":"2021","journal-title":"Curr. Infect. Dis. Rep."},{"key":"10.1016\/j.bios.2025.117896_bib60","doi-asserted-by":"crossref","first-page":"3308","DOI":"10.1128\/JCM.01071-09","article-title":"Streptococcus pneumoniae DNA load in blood as a marker of infection in patients with community-acquired pneumonia","volume":"47","author":"Peters","year":"2009","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.bios.2025.117896_bib61","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1378\/chest.09-0258","article-title":"Severity of pneumococcal pneumonia associated with genomic bacterial load","volume":"136","author":"Rello","year":"2009","journal-title":"Chest"},{"key":"10.1016\/j.bios.2025.117896_bib62","doi-asserted-by":"crossref","first-page":"456","DOI":"10.3390\/ijms22010456","article-title":"Emerging options for the diagnosis of bacterial infections and the characterization of antimicrobial resistance","volume":"22","author":"Rentschler","year":"2021","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.bios.2025.117896_bib63","doi-asserted-by":"crossref","first-page":"966","DOI":"10.1016\/j.tibtech.2018.04.006","article-title":"Exploiting bacteriophage proteomes: the hidden biotechnological potential","volume":"36","author":"Santos","year":"2018","journal-title":"Trends Biotechnol."},{"key":"10.1016\/j.bios.2025.117896_bib64","doi-asserted-by":"crossref","first-page":"347","DOI":"10.1128\/AEM.01616-06","article-title":"Lytic activity of recombinant bacteriophage \u03c611 and \u03c612 endolysins on whole cells and biofilms of Staphylococcus aureus","volume":"73","author":"Sass","year":"2007","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.bios.2025.117896_bib65","doi-asserted-by":"crossref","first-page":"5745","DOI":"10.1128\/AEM.00801-10","article-title":"Rapid multiplex detection and differentiation of listeria cells by use of fluorescent phage endolysin cell wall binding domains","volume":"76","author":"Schmelcher","year":"2010","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.bios.2025.117896_bib66","doi-asserted-by":"crossref","first-page":"1453","DOI":"10.1093\/jac\/dku552","article-title":"Evolutionarily distinct bacteriophage endolysins featuring conserved peptidoglycan cleavage sites protect mice from MRSA infection","volume":"70","author":"Schmelcher","year":"2015","journal-title":"J. Antimicrob. Chemother."},{"key":"10.1016\/j.bios.2025.117896_bib67","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1111\/j.1365-3148.2006.00686.x","article-title":"FACS technology used in a new rapid bacterial detection method","volume":"16","author":"Schmidt","year":"2006","journal-title":"Transfus. Med."},{"key":"10.1016\/j.bios.2025.117896_bib68","doi-asserted-by":"crossref","first-page":"771","DOI":"10.1186\/s12879-022-07751-2","article-title":"Pathogen load and species monitored by droplet digital PCR in patients with bloodstream infections: a prospective case series study","volume":"22","author":"Shao","year":"2022","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.bios.2025.117896_bib69","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s41479-020-00074-3","article-title":"Etiology of community-acquired pneumonia in adults: a systematic review","volume":"12","author":"Shoar","year":"2020","journal-title":"Pneumonia"},{"key":"10.1016\/j.bios.2025.117896_bib70","doi-asserted-by":"crossref","first-page":"402","DOI":"10.3390\/bios14080402","article-title":"A bacteriophage protein-based impedimetric electrochemical biosensor for the detection of Campylobacter jejuni","volume":"14","author":"Suganthan","year":"2024","journal-title":"Biosensors"},{"key":"10.1016\/j.bios.2025.117896_bib71","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1080\/23808993.2018.1425611","article-title":"The role for rapid molecular diagnostic tests for infectious diseases in precision medicine","volume":"3","author":"Tenover","year":"2018","journal-title":"Expert Rev. Precis. Med. Drug Dev."},{"key":"10.1016\/j.bios.2025.117896_bib72","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/S1473-3099(18)30310-4","article-title":"Estimates of the global, regional, and national morbidity, mortality, and aetiologies of lower respiratory infections in 195 countries, 1990\u20132016: a systematic analysis for the global burden of disease study 2016","volume":"18","author":"Troeger","year":"2018","journal-title":"Lancet Infect. Dis."},{"key":"10.1016\/j.bios.2025.117896_bib73","doi-asserted-by":"crossref","DOI":"10.15252\/embr.202256033","article-title":"Fighting antibiotic Resistance\u2014Strategies and (pre) clinical developments to find new antibacterials","volume":"24","author":"Walesch","year":"2023","journal-title":"EMBO Rep."},{"key":"10.1016\/j.bios.2025.117896_bib74","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202411753","article-title":"Enhancing the therapeutic potential of peptide antibiotics using bacteriophage mimicry strategies","volume":"12","author":"Wan","year":"2025","journal-title":"Adv. Sci."},{"key":"10.1016\/j.bios.2025.117896_bib75","doi-asserted-by":"crossref","DOI":"10.1093\/femsre\/fuac025","article-title":"Staphylococcus aureus cell wall maintenance\u2013the multifaceted roles of peptidoglycan hydrolases in bacterial growth, fitness, and virulence","volume":"46","author":"Wang","year":"2022","journal-title":"FEMS Microbiol. Rev."},{"key":"10.1016\/j.bios.2025.117896_bib76","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2021.113189","article-title":"Lateral flow assay of methicillin-resistant Staphylococcus aureus using bacteriophage cellular wall-binding domain as recognition agent","volume":"182","author":"Yang","year":"2021","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117896_bib77","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1007\/s12275-014-4087-z","article-title":"Phage lysis: three steps, three choices, one outcome","volume":"52","author":"Young","year":"2014","journal-title":"J. Microbiol."},{"key":"10.1016\/j.bios.2025.117896_bib78","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1016\/j.bios.2015.09.058","article-title":"Sensitive and rapid detection of Staphylococcus aureus in milk via cell binding domain of lysin","volume":"77","author":"Yu","year":"2016","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117896_bib79","doi-asserted-by":"crossref","first-page":"31681","DOI":"10.1016\/j.ceramint.2021.08.047","article-title":"Synthesis and characterization of nanocomposite Fe3O4\/SiO2 core\u2013shell abrasives for high-efficiency ultrasound-assisted magneto-rheological polishing of sapphire","volume":"47","author":"Zhai","year":"2021","journal-title":"Ceram. Int."},{"key":"10.1016\/j.bios.2025.117896_bib80","doi-asserted-by":"crossref","first-page":"5287","DOI":"10.1038\/s41467-024-49603-4","article-title":"Guiding antibiotics towards their target using bacteriophage proteins","volume":"15","author":"Zhao","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bios.2025.117896_bib81","article-title":"Combining immunomagnetic beads and the phage lysin LysGH15 for fluorescence detection of Staphylococcus aureus","author":"Zhou","year":"2025","journal-title":"Anal. Chim. Acta"}],"updated-by":[{"DOI":"10.1016\/j.bios.2025.118266","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T00:00:00Z","timestamp":1764374400000}},{"DOI":"10.1016\/j.bios.2025.118266","type":"erratum","label":"Erratum","source":"publisher","updated":{"date-parts":[[2026,3,1]],"date-time":"2026-03-01T00:00:00Z","timestamp":1772323200000}}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566325007729?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566325007729?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,6]],"date-time":"2026-03-06T19:32:17Z","timestamp":1772825537000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566325007729"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":81,"alternative-id":["S0956566325007729"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2025.117896","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A bacteriophage protein-driven platform for rapid and precise diagnosis of bacterial pathogens from blood samples","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2025.117896","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117896"}}