{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T03:15:42Z","timestamp":1789874142789,"version":"4.0.1"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R33HD101937"],"award-info":[{"award-number":["R33HD101937"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002701","name":"Ministry of Education","doi-asserted-by":"publisher","award":["RS-2023-00248631"],"award-info":[{"award-number":["RS-2023-00248631"]}],"id":[{"id":"10.13039\/501100002701","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002456","name":"Chonnam National University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002456","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100009633","name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100009633","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000071","name":"National Institute of Child Health and Human Development","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000071","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003725","name":"National Research Foundation of Korea","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100003725","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.bios.2025.117975","type":"journal-article","created":{"date-parts":[[2025,9,6]],"date-time":"2025-09-06T14:55:22Z","timestamp":1757170522000},"page":"117975","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["A self-heating, multi-channel slider cassette for innovative point-of-care molecular diagnostics from whole blood samples"],"prefix":"10.1016","volume":"290","author":[{"ORCID":"https:\/\/orcid.org\/0009-0000-2689-9649","authenticated-orcid":false,"given":"Qingtian","family":"Yin","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-4200-6638","authenticated-orcid":false,"given":"Jihoon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9438-1603","authenticated-orcid":false,"given":"Hyun-Woo","family":"Choi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung-Jung","family":"Kee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruijie","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2021-8424","authenticated-orcid":false,"given":"Youngung","family":"Seok","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haim H.","family":"Bau","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.bios.2025.117975_bib1","doi-asserted-by":"crossref","DOI":"10.1002\/rmv.2215","article-title":"Loop-mediated isothermal amplification (LAMP): an effective molecular point-of-care technique for the rapid diagnosis of coronavirus SARS-CoV-2","volume":"31","author":"Chaouch","year":"2021","journal-title":"Rev. Med. Virol."},{"key":"10.1016\/j.bios.2025.117975_bib2","doi-asserted-by":"crossref","DOI":"10.3389\/fmed.2021.713981","article-title":"HBV\/HIV coinfection: impact on the development and clinical treatment of liver diseases","volume":"8","author":"Cheng","year":"2021","journal-title":"Front. Med."},{"issue":"2","key":"10.1016\/j.bios.2025.117975_bib3","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0031432","article-title":"Isothermal amplification using a chemical heating device for point-of-care detection of HIV-1","volume":"7","author":"Curtis","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.bios.2025.117975_bib4","article-title":"Recent advances in loop-mediated isothermal amplification (LAMP) for rapid and efficient detection of pathogens","volume":"3","author":"Garg","year":"2022","journal-title":"Curr. Res. Microb. Sci."},{"key":"10.1016\/j.bios.2025.117975_bib5","doi-asserted-by":"crossref","DOI":"10.1016\/j.jcv.2023.105613","article-title":"Molecular point-of-care devices for the diagnosis of infectious diseases in resource-limited settings - a review of the current landscape, technical challenges, and clinical impact","volume":"169","author":"Gavina","year":"2023","journal-title":"J. Clin. Virol."},{"issue":"2","key":"10.1016\/j.bios.2025.117975_bib6","first-page":"221","article-title":"The spectrum of HBV\/HCV coinfection: epidemiology, clinical characteristics, viral interactions and management","volume":"28","author":"Konstantinou","year":"2015","journal-title":"Ann. Gastroenterol."},{"issue":"13","key":"10.1016\/j.bios.2025.117975_bib7","doi-asserted-by":"crossref","first-page":"4212","DOI":"10.1039\/D1AN00309G","article-title":"Electricity-free chemical heater for isothermal nucleic acid amplification with applications in COVID-19 home testing","volume":"146","author":"Li","year":"2021","journal-title":"Analyst"},{"issue":"5","key":"10.1016\/j.bios.2025.117975_bib8","doi-asserted-by":"crossref","DOI":"10.3892\/mmr.2023.12991","article-title":"Advances in the application of molecular diagnostic techniques for the detection of infectious disease pathogens","volume":"27","author":"Liu","year":"2023","journal-title":"Mol. Med. Rep."},{"issue":"12","key":"10.1016\/j.bios.2025.117975_bib9","doi-asserted-by":"crossref","DOI":"10.3390\/life13122271","article-title":"Point-of-Care testing for hepatitis viruses: a growing need","volume":"13","author":"Pauly","year":"2023","journal-title":"Life"},{"issue":"3","key":"10.1016\/j.bios.2025.117975_bib10","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1111\/jvh.13217","article-title":"Prevalence and burden of HBV co-infection among people living with HIV: a global systematic review and meta-analysis","volume":"27","author":"Platt","year":"2020","journal-title":"J. Viral Hepat."},{"issue":"10","key":"10.1016\/j.bios.2025.117975_bib11","doi-asserted-by":"crossref","DOI":"10.1128\/jcm.02446-21","article-title":"Forty years of molecular diagnostics for infectious diseases","volume":"60","author":"Schmitz","year":"2022","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.bios.2025.117975_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2024.116292","article-title":"Paper-based loop-mediated isothermal amplification and CRISPR integrated platform for on-site nucleic acid testing of pathogens","volume":"257","author":"Sen","year":"2024","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117975_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2020.112400","article-title":"Lab-on-paper for all-in-one molecular diagnostics (LAMDA) of zika, dengue, and chikungunya virus from human serum","volume":"165","author":"Seok","year":"2020","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117975_bib14","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2022.132353","article-title":"Manually-operated, slider cassette for multiplexed molecular detection at the point of care","volume":"369","author":"Seok","year":"2022","journal-title":"Sensor. Actuator. B Chem."},{"key":"10.1016\/j.bios.2025.117975_bib15","article-title":"Insights into the coinfections of human immunodeficiency virus-hepatitis B virus, human immunodeficiency virus-hepatitis C virus, and hepatitis B virus-hepatitis C virus: prevalence, risk factors, pathogenesis, diagnosis, and treatment","volume":"12","author":"Shahriar","year":"2021","journal-title":"Front. Microbiol."},{"key":"10.1016\/j.bios.2025.117975_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.nantod.2021.101092","article-title":"Point-of-care diagnostics for infectious diseases: from methods to devices","volume":"37","author":"Wang","year":"2021","journal-title":"Nano Today"},{"key":"10.1016\/j.bios.2025.117975_bib17","series-title":"Global Hepatitis Report","year":"2017"},{"key":"10.1016\/j.bios.2025.117975_bib18","series-title":"Global Hepatitis Report 2024: Action for Access in low- and middle-income Countries","year":"2024"},{"key":"10.1016\/j.bios.2025.117975_bib19","series-title":"HIV Statistics, Globally and by WHO Region","year":"2024"},{"issue":"Suppl. 6","key":"10.1016\/j.bios.2025.117975_bib20","article-title":"Diagnosing sexually transmitted infections in resource-constrained settings: challenges and ways forward","volume":"22","author":"Wi","year":"2019","journal-title":"J. Int. AIDS Soc."},{"issue":"11","key":"10.1016\/j.bios.2025.117975_bib21","doi-asserted-by":"crossref","first-page":"2923","DOI":"10.1007\/s00216-021-03224-8","article-title":"Multiplex detection of blood-borne pathogens on a self-driven microfluidic chip using loop-mediated isothermal amplification","volume":"413","author":"Xie","year":"2021","journal-title":"Anal. Bioanal. Chem."},{"key":"10.1016\/j.bios.2025.117975_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodcont.2022.108824","article-title":"Multiplex detection of foodborne pathogens by real-time loop-mediated isothermal amplification on a digital microfluidic chip","volume":"136","author":"Xie","year":"2022","journal-title":"Food Control"}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566325008516?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566325008516?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T09:35:09Z","timestamp":1772876109000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566325008516"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":22,"alternative-id":["S0956566325008516"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2025.117975","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A self-heating, multi-channel slider cassette for innovative point-of-care molecular diagnostics from whole blood samples","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2025.117975","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"117975"}}