{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,11]],"date-time":"2026-10-11T13:35:31Z","timestamp":1791725731505,"version":"4.3.4"},"reference-count":35,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004607","name":"Natural Science Foundation of Guangxi Province","doi-asserted-by":"publisher","award":["2024GXNSFAA010431"],"award-info":[{"award-number":["2024GXNSFAA010431"]}],"id":[{"id":"10.13039\/501100004607","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22464004"],"award-info":[{"award-number":["22464004"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22264004"],"award-info":[{"award-number":["22264004"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.bios.2025.117985","type":"journal-article","created":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T22:03:28Z","timestamp":1757541808000},"page":"117985","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":17,"special_numbering":"C","title":["Smartphone-integrated tri-mode RCA-CRISPR\/Cas12a biosensor with Fe3O4@Au nanozyme for on-site detection of sugarcane smut at attomolar level"],"prefix":"10.1016","volume":"290","author":[{"given":"Rongshuai","family":"Che","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danyao","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingtao","family":"Fu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Wen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeping","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Defen","family":"Feng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ke-Jing","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bios.2025.117985_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2024.116271","article-title":"Two-dimensional metal-organic framework nanozyme-mediated portable paper-based analytical device for dichlorophen assay","volume":"255","author":"Chang","year":"2024","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117985_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.138403","article-title":"Dual-modal improved biosensing platform for sugarcane smut pathogen based on biological enzyme-Mg2+ DNAzyme coupled with DNA transporter cascading hybridization chain reaction","volume":"286","author":"Che","year":"2025","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.bios.2025.117985_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.trac.2024.117798","article-title":"Recent progress in dual\/multi-modal detection modes for improving sensitivity and specificity of lateral flow immunoassays applied for point-of-care diagnostics","volume":"177","author":"Chowdhury","year":"2024","journal-title":"Trac-Trend. Anal. Chem."},{"key":"10.1016\/j.bios.2025.117985_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2025.117182","article-title":"Sensitivity-enhanced self-powered biosensing platform for detection of sugarcane smut using Mn-doped ZIF-67, RCA-DNA nano-grid array and capacitor","volume":"273","author":"Fu","year":"2025","journal-title":"Biosens. Bioelectron."},{"issue":"1","key":"10.1016\/j.bios.2025.117985_bib5","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1021\/acs.analchem.4c05692","article-title":"Portable Self-Powered\/Colorimetric dual-mode sensing platform based on multifunctional bioconjugates for precise On-Site detection of acetamiprid","volume":"97","author":"Gu","year":"2025","journal-title":"Anal. Chem."},{"issue":"22","key":"10.1016\/j.bios.2025.117985_bib6","doi-asserted-by":"crossref","first-page":"13949","DOI":"10.1021\/acs.jafc.5c04580","article-title":"Fe3O4@Au nanoparticle-enabled magnetic separation coupled with CRISPR\/Cas12a for ultrasensitive detection of foodborne pathogens","volume":"73","author":"Guo","year":"2025","journal-title":"J. Agric. Food Chem."},{"issue":"39","key":"10.1016\/j.bios.2025.117985_bib7","doi-asserted-by":"crossref","DOI":"10.1002\/adfm.202403122","article-title":"Multi-Mode\/Signal biosensors: electrochemical integrated sensing techniques","volume":"34","author":"Han","year":"2024","journal-title":"Adv. Funct. Mater."},{"issue":"5","key":"10.1016\/j.bios.2025.117985_bib8","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1002\/bmb.21552","article-title":"Real-time quantitative PCR: a tool for absolute and relative quantification","volume":"49","author":"Harshitha","year":"2021","journal-title":"Biochem. Mol. Biol. Edu."},{"issue":"5","key":"10.1016\/j.bios.2025.117985_bib9","doi-asserted-by":"crossref","first-page":"3026","DOI":"10.1021\/acs.analchem.4c06066","article-title":"DNAzyme-Triggered equilibrium transfer with self-activated CRISPR-Cas12a biosensor enables one-pot diagnosis of nucleic acids","volume":"97","author":"Huang","year":"2025","journal-title":"Anal. Chem."},{"issue":"5","key":"10.1016\/j.bios.2025.117985_bib10","doi-asserted-by":"crossref","DOI":"10.1016\/j.cclet.2022.107820","article-title":"Modification and application of Fe3O4 nanozymes in analytical chemistry: a review","volume":"34","author":"Ju","year":"2023","journal-title":"Chin. Chem. Lett."},{"issue":"5","key":"10.1016\/j.bios.2025.117985_bib11","article-title":"Sulfur-doped graphdiyne as a high-capacity anode material for lithium-ion batteries","volume":"11","author":"Kong","year":"2021","journal-title":"Nanomaterials-Base."},{"key":"10.1016\/j.bios.2025.117985_bib12","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2025.117310","article-title":"Functional metal organic framework mediated G-quadruplex DNA nanostructures for improved self-powered smartphone-assisted dual-mode biosensing","volume":"278","author":"Li","year":"2025","journal-title":"Biosens. Bioelectron."},{"issue":"51","key":"10.1016\/j.bios.2025.117985_bib13","doi-asserted-by":"crossref","first-page":"34656","DOI":"10.1021\/acsnano.4c09982","article-title":"Nanozyme as tumor energy homeostasis disruptor to augment Cascade catalytic therapy","volume":"18","author":"Li","year":"2024","journal-title":"ACS Nano"},{"issue":"34","key":"10.1016\/j.bios.2025.117985_bib14","doi-asserted-by":"crossref","first-page":"11792","DOI":"10.1021\/acs.analchem.1c02286","article-title":"Metal-organic framework-functionalized paper-based electrochemical biosensor for ultrasensitive exosome assay","volume":"93","author":"Liu","year":"2021","journal-title":"Anal. Chem."},{"issue":"4","key":"10.1016\/j.bios.2025.117985_bib15","doi-asserted-by":"crossref","first-page":"562","DOI":"10.1021\/acssensors.7b00081","article-title":"Label-free homogeneous electroanalytical platform for pesticide detection based on acetylcholinesterase-mediated DNA conformational switch integrated with rolling circle amplification","volume":"2","author":"Liu","year":"2017","journal-title":"ACS Sens."},{"issue":"15","key":"10.1016\/j.bios.2025.117985_bib16","doi-asserted-by":"crossref","first-page":"8275","DOI":"10.1021\/acs.analchem.4c06042","article-title":"High-performance biosensing platforms based on enzyme-linked nucleic acid amplification regulated by synergistic allosteric hairpin catalysis of Bimetallic nanozymes and its mechanisms","volume":"97","author":"Ma","year":"2025","journal-title":"Anal. Chem."},{"issue":"46","key":"10.1016\/j.bios.2025.117985_bib17","doi-asserted-by":"crossref","first-page":"18464","DOI":"10.1021\/acs.analchem.4c03846","article-title":"Multispatially localized DNA walker coupling covalent organic framework for dual-mode detection of nucleocapsid protein using the walking-recycling-conversion strategy","volume":"96","author":"Qiu","year":"2024","journal-title":"Anal. Chem."},{"issue":"1","key":"10.1016\/j.bios.2025.117985_bib18","article-title":"Screening of sugarcane germplasm against Sporisorium scitamineum and its effects on setts germination and tillering","volume":"14","author":"Rajput","year":"2024","journal-title":"Sci. Rep-Uk"},{"key":"10.1016\/j.bios.2025.117985_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2023.115245","article-title":"An integrated and flexible PDMS\/Au film-based electrochemical immunosensor via Fe-Co MOF as a signal amplifier for alpha fetoprotein detection","volume":"230","author":"Shang","year":"2023","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2025.117985_bib20","doi-asserted-by":"crossref","DOI":"10.1155\/2013\/942682","article-title":"A TaqMan real-time PCR assay for detection and quantification of Sporisorium scitamineum in sugarcane","author":"Su","year":"2013","journal-title":"Sci. World J."},{"key":"10.1016\/j.bios.2025.117985_bib21","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.156912","article-title":"Design of a portable bioassay system based on highly efficent nanozyme and Au-DNA nanocluster: toward current\/colorimetric dual-signal detection of sugarcane smut","volume":"500","author":"Tang","year":"2024","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.bios.2025.117985_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2024.127321","article-title":"Super signal-enhancement biosensing platform for precise target recognition based on rolling circle-hybridization chain dual linear cascade amplification technology","volume":"285","author":"Tang","year":"2025","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2025.117985_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2025.144586","article-title":"A dual-mode sensor for rapid detection of procymidone: \u201cdark box\u201d qualitative analysis and electrochemical quantification mediated by PdHPCN-222\/PEI-rGO and CRISPR\/Cas12a","volume":"486","author":"Wang","year":"2025","journal-title":"Food Chem."},{"issue":"51","key":"10.1016\/j.bios.2025.117985_bib24","doi-asserted-by":"crossref","first-page":"20152","DOI":"10.1021\/acs.analchem.4c03572","article-title":"Efficient electrochemical coupling of aptamer to nanoelectrode for in situ detection of ATP in single cells","volume":"96","author":"Wang","year":"2024","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2025.117985_bib25","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2025.117548","article-title":"From leaf to lab-on-cloth: spatial DNA nanorobotics and 2D graphyne synergy enable ultra-precise electrochemical tracking of sugarcane pokkah boeng disease","volume":"283","author":"Wu","year":"2025","journal-title":"Biosens. Bioelectron."},{"issue":"1","key":"10.1016\/j.bios.2025.117985_bib26","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1038\/s41467-020-20823-8","article-title":"A metal-free photocatalyst for highly efficient hydrogen peroxide photoproduction in real seawater (vol 12, 483, 2021)","volume":"12","author":"Wu","year":"2021","journal-title":"Nat. Commun."},{"issue":"9","key":"10.1016\/j.bios.2025.117985_bib27","doi-asserted-by":"crossref","first-page":"8812","DOI":"10.1021\/acsnano.4c16423","article-title":"Machine learning-aided intelligent monitoring of multivariate miRNA biomarkers using bipolar self-powered sensors","volume":"19","author":"Xu","year":"2025","journal-title":"ACS Nano"},{"key":"10.1016\/j.bios.2025.117985_bib28","doi-asserted-by":"crossref","DOI":"10.1016\/j.jhazmat.2022.129491","article-title":"Electrochemical aptasensor based on Ce3NbO7\/CeO2@Au hollow nanospheres by using Nb.BbvCI-triggered and bipedal DNA walker amplification strategy for zearalenone detection","volume":"438","author":"Yan","year":"2022","journal-title":"J. Hazard. Mater."},{"issue":"4","key":"10.1016\/j.bios.2025.117985_bib29","doi-asserted-by":"crossref","first-page":"2176","DOI":"10.1021\/acs.analchem.4c05181","article-title":"CRISPR-based homogeneous electrochemical strategy for near-zero background detection of breast cancer extracellular vesicles via fluidity-enhanced magnetic capture nanoprobe","volume":"97","author":"Yang","year":"2025","journal-title":"Anal. Chem."},{"issue":"4","key":"10.1016\/j.bios.2025.117985_bib30","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.1021\/acs.analchem.4c05700","article-title":"Aptamer-proximity ligation coupled with rolling circle amplification strategy for an ultrasensitive analysis of tumor-derived extracellular vesicles PD-L1","volume":"97","author":"Ye","year":"2025","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2025.117985_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.cej.2024.158980","article-title":"Highly conductive MXene-Au NPs and high current AuPdNPs\/UiO-66 electrochemical sensor combining multiple signal amplification strategies for tetracycline detection","volume":"504","author":"Zhang","year":"2025","journal-title":"Chem. Eng. J."},{"key":"10.1016\/j.bios.2025.117985_bib32","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2025.137636","article-title":"\u201cSuperior snowflake\u201d AuPd\/Cu2S as substrate and satellite-like Au\/CeO2 as signal probe to improve the sensitivity of electrochemical sensor for kanamycin detection","volume":"435","author":"Zhang","year":"2025","journal-title":"Sens. Actuators B-Chem."},{"key":"10.1016\/j.bios.2025.117985_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.aca.2024.343072","article-title":"Triple-helix molecular-switch-actuated rolling circle amplification and catalytic hairpin assembly multistage signal amplified fluorescent aptasensor for detection of aflatoxin B1","volume":"1323","author":"Zhang","year":"2024","journal-title":"Anal. Chim. Acta"},{"issue":"5","key":"10.1016\/j.bios.2025.117985_bib34","doi-asserted-by":"crossref","first-page":"1852","DOI":"10.1021\/acs.analchem.3c03423","article-title":"A portable self-powered electrochemical sensor based on zinc-air battery for detection of hydrogen sulfide","volume":"96","author":"Zhu","year":"2024","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2025.117985_bib35","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2022.114076","article-title":"PAM-free loop-mediated isothermal amplification coupled with CRISPR\/Cas12a cleavage (Cas-PfLAMP) for rapid detection of rice pathogens","volume":"204","author":"Zhu","year":"2022","journal-title":"Biosens. Bioelectron."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566325008619?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566325008619?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T17:32:27Z","timestamp":1778779947000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566325008619"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":35,"alternative-id":["S0956566325008619"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2025.117985","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Smartphone-integrated tri-mode RCA-CRISPR\/Cas12a biosensor with Fe3O4@Au nanozyme for on-site detection of sugarcane smut at attomolar level","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2025.117985","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"117985"}}