{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T22:31:50Z","timestamp":1787697110324,"version":"build-2784847793"},"reference-count":33,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100018553","name":"Science and Technology Plan Project of Wenzhou Municipality","doi-asserted-by":"publisher","award":["G2023042"],"award-info":[{"award-number":["G2023042"]}],"id":[{"id":"10.13039\/501100018553","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100018553","name":"Science and Technology Plan Project of Wenzhou Municipality","doi-asserted-by":"publisher","award":["Y2023024"],"award-info":[{"award-number":["Y2023024"]}],"id":[{"id":"10.13039\/501100018553","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007958","name":"Wenzhou University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007958","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32002312"],"award-info":[{"award-number":["32002312"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22175132"],"award-info":[{"award-number":["22175132"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004731","name":"Natural Science Foundation of Zhejiang Province","doi-asserted-by":"publisher","award":["LY24B050003"],"award-info":[{"award-number":["LY24B050003"]}],"id":[{"id":"10.13039\/501100004731","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.bios.2025.118010","type":"journal-article","created":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:33:07Z","timestamp":1758587587000},"page":"118010","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":5,"special_numbering":"C","title":["SiNWs-DNA nanoprobes functionalized microchannel for rapid and ultrasensitive virus sensing"],"prefix":"10.1016","volume":"290","author":[{"given":"Yueyue","family":"Feng","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiwei","family":"Xu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guofeng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liying","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7557-5883","authenticated-orcid":false,"given":"Yajun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengpeng","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9235-2633","authenticated-orcid":false,"given":"Nannan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"4","key":"10.1016\/j.bios.2025.118010_bib1","doi-asserted-by":"crossref","DOI":"10.1128\/spectrum.00088-23","article-title":"Analytical and clinical evaluation of a TaqMan real-time PCR assay for the detection of Chikungunya virus","volume":"11","author":"Andrew","year":"2023","journal-title":"Microbiol. Spectr."},{"key":"10.1016\/j.bios.2025.118010_bib2","doi-asserted-by":"crossref","first-page":"193","DOI":"10.1038\/s41579-021-00639-z","article-title":"Infectious disease in an era of global change","volume":"20","author":"Baker","year":"2021","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.bios.2025.118010_bib3","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1038\/s41565-022-01287-x","article-title":"Simultaneous identification of viruses and viral variants with programmable DNA nanobait","volume":"18","author":"Bo\u0161kovi\u0107","year":"2023","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.bios.2025.118010_bib4","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1038\/s41564-019-0637-9","article-title":"Metagenomic sequencing with spiked primer enrichment for viral diagnostics and genomic surveillance","volume":"5","author":"Deng","year":"2020","journal-title":"Nat. Microbiol."},{"key":"10.1016\/j.bios.2025.118010_bib5","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1017\/S0950268808001167","article-title":"Atypical Chikungunya virus infections: clinical manifestations, mortality and risk factors for severe disease during the 2005-2006 outbreak on R\u00e9union","volume":"137","author":"Economopoulou","year":"2008","journal-title":"Epidemiol. Infect."},{"key":"10.1016\/j.bios.2025.118010_bib6","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1080\/08820139.2020.1733011","article-title":"Chikungunya virus infection outcome: a systematic review of host genetics","volume":"50","author":"Ferreira","year":"2020","journal-title":"Immunol. Investig."},{"key":"10.1016\/j.bios.2025.118010_bib7","doi-asserted-by":"crossref","first-page":"201","DOI":"10.1038\/nmeth.4577","article-title":"Highly parallel direct RNA sequencing on an array of nanopores","volume":"15","author":"Garalde","year":"2018","journal-title":"Nat. Methods"},{"key":"10.1016\/j.bios.2025.118010_bib8","doi-asserted-by":"crossref","DOI":"10.1590\/1414-431x2023e12557","article-title":"Influence of host genetic polymorphisms involved in immune response and their role in the development of Chikungunya disease: a review","volume":"56","author":"Gotay","year":"2023","journal-title":"Braz. J. Med. Biol. Res."},{"key":"10.1016\/j.bios.2025.118010_bib9","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0010829","article-title":"Development and evaluation of recombinant E2 protein based IgM capture enzyme-linked immunosorbent assay (ELISA) and double antigen sandwich ELISA for detection of antibodies to Chikungunya virus","volume":"16","author":"Guo","year":"2022","journal-title":"PLoS Neglected Trop. Dis."},{"key":"10.1016\/j.bios.2025.118010_bib10","doi-asserted-by":"crossref","first-page":"643","DOI":"10.1038\/s41551-021-00760-7","article-title":"CRISPR-based diagnostics","volume":"5","author":"Kaminski","year":"2021","journal-title":"Nat. Biomed. Eng."},{"key":"10.1016\/j.bios.2025.118010_bib11","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/0166-0934(85)90139-9","article-title":"Detection of chikungunya virus antigen in Aedes albopictus mosquitoes by enzyme-linked immunosorbent assay","volume":"12","author":"Konishi","year":"1985","journal-title":"J. Virol. Methods"},{"key":"10.1016\/j.bios.2025.118010_bib12","article-title":"Combating the coronavirus pandemic: early detection, medical treatment, and a concerted effort by the global community","volume":"2020","author":"Luo","year":"2020","journal-title":"Res."},{"key":"10.1016\/j.bios.2025.118010_bib13","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijid.2024.107226","article-title":"Prevalence of dengue, Zika, and chikungunya virus infections among mosquitoes in Asia: a systematic review and meta-analysis","volume":"148","author":"Maneerattanasak","year":"2024","journal-title":"Int. J. Infect. Dis."},{"key":"10.1016\/j.bios.2025.118010_bib14","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.diagmicrobio.2018.06.019","article-title":"Detection of Zika, dengue and chikungunya viruses using single-reaction multiplex real-time RT-PCR","volume":"92","author":"Mansuy","year":"2018","journal-title":"Diagn. Microbiol. Infect. Dis."},{"key":"10.1016\/j.bios.2025.118010_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2022.104145","article-title":"Biological nanopores for single-molecule sensing","volume":"25","author":"Mayer","year":"2022","journal-title":"iScience"},{"key":"10.1016\/j.bios.2025.118010_bib16","doi-asserted-by":"crossref","first-page":"1255","DOI":"10.1016\/j.cell.2016.04.059","article-title":"Rapid, low-cost detection of zika virus using programmable biomolecular components","volume":"165","author":"Pardee","year":"2016","journal-title":"Cell"},{"key":"10.1016\/j.bios.2025.118010_bib17","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1128\/JCM.01734-06","article-title":"Rapid and real-time detection of Chikungunya Virus by reverse Transcription loop-mediated isothermal amplification assay","volume":"45","author":"Parida","year":"2007","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.bios.2025.118010_bib18","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pntd.0004953","article-title":"A field-deployable reverse transcription recombinase polymerase amplification assay for rapid detection of the Chikungunya virus","volume":"10","author":"Patel","year":"2016","journal-title":"PLoS Neglected Trop. Dis."},{"key":"10.1016\/j.bios.2025.118010_bib19","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.abh2848","article-title":"Direct detection of human adenovirus or SARS-CoV-2 with ability to inform infectivity using DNA aptamer-nanopore sensors","volume":"7","author":"Peinetti","year":"2021","journal-title":"Sci. Adv."},{"key":"10.1016\/j.bios.2025.118010_bib20","doi-asserted-by":"crossref","first-page":"7362","DOI":"10.1038\/s41467-023-43004-9","article-title":"Multiplexed detection of viral antigen and RNA using nanopore sensing and encoded molecular probes","volume":"14","author":"Ren","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bios.2025.118010_bib21","doi-asserted-by":"crossref","first-page":"1391","DOI":"10.1038\/s41467-018-03772-1","article-title":"Performance of the Trioplex real-time RT-PCR assay for detection of Zika, dengue, and chikungunya viruses","volume":"9","author":"Santiago","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bios.2025.118010_bib22","doi-asserted-by":"crossref","first-page":"3726","DOI":"10.1038\/s41467-021-24001-2","article-title":"Combining machine learning and nanopore construction creates an artificial intelligence nanopore for coronavirus detection","volume":"12","author":"Taniguchi","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.bios.2025.118010_bib23","doi-asserted-by":"crossref","first-page":"598","DOI":"10.1021\/acsnano.5b05622","article-title":"Ultrasensitive detection of Ebola virus Oligonucleotide based on upconversion Nanoprobe\/Nanoporous membrane System","volume":"10","author":"Tsang","year":"2016","journal-title":"ACS Nano"},{"key":"10.1016\/j.bios.2025.118010_bib24","doi-asserted-by":"crossref","first-page":"15695","DOI":"10.1021\/acsnano.4c01888","article-title":"Identifying viral vector characteristics by Nanopore sensing","volume":"18","author":"Tsutsui","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.bios.2025.118010_bib25","doi-asserted-by":"crossref","DOI":"10.1038\/530167a","article-title":"Sequencing on the ground","volume":"530","author":"Turner","year":"2016","journal-title":"Nature"},{"key":"10.1016\/j.bios.2025.118010_bib26","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1038\/nature05448","article-title":"Requirements for high impact diagnostics in the developing world","volume":"444","author":"Urdea","year":"2006","journal-title":"Nature"},{"key":"10.1016\/j.bios.2025.118010_bib27","first-page":"1003","article-title":"Chikungunya","volume":"33","author":"Vairo","year":"2019","journal-title":"Infect. Dis. Clin."},{"key":"10.1016\/j.bios.2025.118010_bib28","doi-asserted-by":"crossref","first-page":"1150","DOI":"10.1038\/s41551-020-00655-z","article-title":"Rapid lateral flow immunoassay for the fluorescence detection of SARS-CoV-2 RNA","volume":"4","author":"Wang","year":"2020","journal-title":"Nat. Biomed. Eng."},{"key":"10.1016\/j.bios.2025.118010_bib29","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/s43856-022-00147-y","article-title":"Comparative analyses of eighteen rapid antigen tests and RT-PCR for COVID-19 quarantine and surveillance-based isolation","volume":"2","author":"Wells","year":"2022","journal-title":"Commun. Med."},{"key":"10.1016\/j.bios.2025.118010_bib30","doi-asserted-by":"crossref","first-page":"7470","DOI":"10.1021\/acs.analchem.3c05839","article-title":"PNA-Functionalized, Silica Nanowires-Filled glass microtube for ultrasensitive and label-free detection of miRNA-21","volume":"96","author":"Xu","year":"2024","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2025.118010_bib31","doi-asserted-by":"crossref","first-page":"8375","DOI":"10.1002\/anie.201603644","article-title":"Synthesis of discrete alkyl\u2010silica hybrid nanowires and their assembly into nanostructured superhydrophobic membranes","volume":"55","author":"Yi","year":"2016","journal-title":"Angew. Chem. Int. Ed."},{"key":"10.1016\/j.bios.2025.118010_bib32","doi-asserted-by":"crossref","first-page":"3701","DOI":"10.1021\/acs.analchem.1c05571","article-title":"Highly sensitive glass nanopipette sensor using composite probes of DNA-Functionalized metal-organic frameworks","volume":"94","author":"Zhang","year":"2022","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2025.118010_bib34","first-page":"290","article-title":"Improving the specificity of nucleic acid detection with endonuclease-actuated degradation. Commun","volume":"5","author":"Zou","year":"2022","journal-title":"Biol."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566325008863?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566325008863?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T04:18:29Z","timestamp":1773116309000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566325008863"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":33,"alternative-id":["S0956566325008863"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2025.118010","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"SiNWs-DNA nanoprobes functionalized microchannel for rapid and ultrasensitive virus sensing","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2025.118010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"118010"}}