{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T21:17:26Z","timestamp":1789766246068,"version":"4.0.1"},"reference-count":28,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100004853","name":"The Chinese University of Hong Kong","doi-asserted-by":"publisher","award":["69006662"],"award-info":[{"award-number":["69006662"]}],"id":[{"id":"10.13039\/501100004853","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010877","name":"Shenzhen Science and Technology Innovation Committee","doi-asserted-by":"publisher","award":["JCYJ20240813153115021"],"award-info":[{"award-number":["JCYJ20240813153115021"]}],"id":[{"id":"10.13039\/501100010877","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003453","name":"Guangdong Provincial Natural Science Foundation","doi-asserted-by":"publisher","award":["2025A1515011202"],"award-info":[{"award-number":["2025A1515011202"]}],"id":[{"id":"10.13039\/501100003453","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100007567","name":"City University of Hong Kong","doi-asserted-by":"publisher","award":["11218025"],"award-info":[{"award-number":["11218025"]}],"id":[{"id":"10.13039\/100007567","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002920","name":"University Grants Committee Research Grants Council","doi-asserted-by":"publisher","award":["HLCA\/M-113\/25"],"award-info":[{"award-number":["HLCA\/M-113\/25"]}],"id":[{"id":"10.13039\/501100002920","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100007162","name":"Guangdong Provincial Department of Science and Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007162","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.bios.2026.118400","type":"journal-article","created":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T08:02:42Z","timestamp":1768291362000},"page":"118400","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["A microfluidic microspheres accumulation platform for direct visualization of urine albumin-to-creatinine ratio in patients with chronic kidney disease"],"prefix":"10.1016","volume":"298","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4863-7698","authenticated-orcid":false,"given":"Chenyu","family":"Cui","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hogi","family":"Hartanto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinxue","family":"Yin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiaheng","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Choi Wan","family":"Luk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cheuk Chun","family":"Szeto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4517-7750","authenticated-orcid":false,"given":"Ting-Hsuan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bios.2026.118400_bib1","first-page":"59","article-title":"J. Netw","volume":"115","author":"Akraa","year":"2018","journal-title":"Comput. Appl."},{"issue":"17","key":"10.1016\/j.bios.2026.118400_bib2","doi-asserted-by":"crossref","first-page":"10700","DOI":"10.1021\/acs.est.0c00441","volume":"54","author":"Bhardwaj","year":"2020","journal-title":"Environ. Sci. Technol."},{"issue":"9","key":"10.1016\/j.bios.2026.118400_bib3","doi-asserted-by":"crossref","first-page":"1860","DOI":"10.1007\/s00125-016-4008-2","volume":"59","author":"Cherney","year":"2016","journal-title":"Diabetol"},{"issue":"20","key":"10.1016\/j.bios.2026.118400_bib4","doi-asserted-by":"crossref","first-page":"2506","DOI":"10.1021\/ac00147a014","volume":"59","author":"Clayton","year":"2002","journal-title":"Anal. Chem."},{"issue":"10225","key":"10.1016\/j.bios.2026.118400_bib5","doi-asserted-by":"crossref","first-page":"662","DOI":"10.1016\/S0140-6736(19)32977-0","volume":"395","author":"Cockwell","year":"2020","journal-title":"Lancet"},{"issue":"2","key":"10.1016\/j.bios.2026.118400_bib6","first-page":"83","volume":"4","author":"Delanghe","year":"2011","journal-title":"NDT Plus"},{"issue":"3","key":"10.1016\/j.bios.2026.118400_bib7","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1093\/clinchem\/14.3.222","volume":"14","author":"Husdan","year":"1968","journal-title":"Clin. Chem."},{"key":"10.1016\/j.bios.2026.118400_bib8","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.snb.2016.07.158","volume":"239","author":"Lai","year":"2017","journal-title":"Sensor. Actuator. B Chem."},{"issue":"1","key":"10.1016\/j.bios.2026.118400_bib9","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-025-96916-5","volume":"15","author":"Larpant","year":"2025","journal-title":"Sci. Rep."},{"issue":"1","key":"10.1016\/j.bios.2026.118400_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/mas.20100","volume":"26","author":"Lavagnini","year":"2007","journal-title":"Mass Spectrom. Rev."},{"issue":"1","key":"10.1016\/j.bios.2026.118400_bib11","doi-asserted-by":"crossref","first-page":"255","DOI":"10.2307\/2532051","volume":"45","author":"Lawrence","year":"1989","journal-title":"Biometrics"},{"issue":"10","key":"10.1016\/j.bios.2026.118400_bib12","doi-asserted-by":"crossref","first-page":"463","DOI":"10.3390\/bios14100463","volume":"14","author":"Lee","year":"2024","journal-title":"Biosensors"},{"issue":"3","key":"10.1016\/j.bios.2026.118400_bib13","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1109\/TBCAS.2021.3087475","volume":"15","author":"Lee","year":"2021","journal-title":"IEEE Trans. Biomed. Circuits Syst."},{"issue":"1","key":"10.1016\/j.bios.2026.118400_bib14","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1080\/14737159.2020.1699063","volume":"20","author":"Lei","year":"2020","journal-title":"Expert Rev. Mol. Diagn."},{"key":"10.1016\/j.bios.2026.118400_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2021.129915","volume":"340","author":"Lewi\u0144ska","year":"2021","journal-title":"Sensor. Actuator. B Chem."},{"issue":"1","key":"10.1016\/j.bios.2026.118400_bib16","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1038\/s41378-019-0074-1","volume":"5","author":"Liu","year":"2019","journal-title":"Microsyst Nanoeng"},{"issue":"23","key":"10.1016\/j.bios.2026.118400_bib17","doi-asserted-by":"crossref","first-page":"6202","DOI":"10.1039\/D5LC00496A","volume":"25","author":"Lyu","year":"2025","journal-title":"Lab Chip"},{"issue":"8476","key":"10.1016\/j.bios.2026.118400_bib18","doi-asserted-by":"crossref","first-page":"307","DOI":"10.1016\/S0140-6736(86)90837-8","volume":"327","author":"Martin Bland","year":"1986","journal-title":"Lancet"},{"key":"10.1016\/j.bios.2026.118400_bib19","doi-asserted-by":"crossref","first-page":"476","DOI":"10.1016\/j.snb.2016.11.057","volume":"242","author":"Mathaweesansurn","year":"2017","journal-title":"Sensor. Actuator. B Chem."},{"issue":"2","key":"10.1016\/j.bios.2026.118400_bib20","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1093\/fampra\/cms057","volume":"30","author":"Nagrebetsky","year":"2013","journal-title":"Fam. Pract."},{"issue":"2","key":"10.1016\/j.bios.2026.118400_bib21","volume":"12","author":"Park","year":"2017","journal-title":"PLoS One"},{"issue":"6","key":"10.1016\/j.bios.2026.118400_bib22","doi-asserted-by":"crossref","first-page":"426","DOI":"10.7326\/M20-0529","volume":"173","author":"Sumida","year":"2020","journal-title":"Ann. Intern. Med."},{"key":"10.1016\/j.bios.2026.118400_bib23","doi-asserted-by":"crossref","DOI":"10.1016\/j.talanta.2022.124131","volume":"254","author":"Teekayupak","year":"2023","journal-title":"Talanta"},{"issue":"21","key":"10.1016\/j.bios.2026.118400_bib24","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1007\/s10337-012-2324-3","volume":"75","author":"Wang","year":"2012","journal-title":"Chromatographia"},{"issue":"8","key":"10.1016\/j.bios.2026.118400_bib25","doi-asserted-by":"crossref","first-page":"1544","DOI":"10.1093\/clinchem\/32.8.1544","volume":"32","author":"Watts","year":"1986","journal-title":"Clin. Chem."},{"issue":"8","key":"10.1016\/j.bios.2026.118400_bib26","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1038\/nrneph.2015.85","volume":"11","author":"Wouters","year":"2015","journal-title":"Nat. Rev. Nephrol."},{"key":"10.1016\/j.bios.2026.118400_bib27","article-title":"Chronic kidney disease: strategies to retard progression","author":"Yan","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.bios.2026.118400_bib28","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1016\/j.aca.2005.03.027","volume":"541","author":"Zhao","year":"2005","journal-title":"Anal. Chim. Acta"}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566326000321?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566326000321?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T05:38:00Z","timestamp":1778564280000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566326000321"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":28,"alternative-id":["S0956566326000321"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2026.118400","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"A microfluidic microspheres accumulation platform for direct visualization of urine albumin-to-creatinine ratio in patients with chronic kidney disease","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2026.118400","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"118400"}}