{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T17:11:00Z","timestamp":1792602660789,"version":"4.5.0"},"reference-count":20,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T00:00:00Z","timestamp":1780272000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012476","name":"Fundamental Research Funds for Central Universities of the Central South University","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100012476","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012164","name":"National High-tech Research and Development Program","doi-asserted-by":"publisher","award":["2022YFC2403301"],"award-info":[{"award-number":["2022YFC2403301"]}],"id":[{"id":"10.13039\/501100012164","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62074016"],"award-info":[{"award-number":["62074016"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012236","name":"Beijing Institute of Technology Research Fund Program for Young Scholars","doi-asserted-by":"publisher","award":["3160011181907"],"award-info":[{"award-number":["3160011181907"]}],"id":[{"id":"10.13039\/501100012236","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005085","name":"Beijing Institute of Technology","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005085","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011410","name":"National Key Laboratory of Science and Technology on Micro\/Nano Fabrication","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100011410","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100012226","name":"Fundamental Research Funds for the Central Universities","doi-asserted-by":"publisher","award":["2023CX11011"],"award-info":[{"award-number":["2023CX11011"]}],"id":[{"id":"10.13039\/501100012226","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2026,6]]},"DOI":"10.1016\/j.bios.2026.118565","type":"journal-article","created":{"date-parts":[[2026,2,26]],"date-time":"2026-02-26T08:52:31Z","timestamp":1772095951000},"page":"118565","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["MASEA: A microfluidic system for in situ evaluation of tumor angiogenesis in PDO\u2013endothelial co-culture"],"prefix":"10.1016","volume":"302","author":[{"given":"Xin","family":"Wu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daoyun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingyao","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuzhi","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhicheng","family":"Huang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhibo","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chao","family":"Gao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuxiao","family":"Lin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhina","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kang","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Naixin","family":"Liang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2608-5802","authenticated-orcid":false,"given":"Zewen","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.bios.2026.118565_bib1","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-020-67289-8","volume":"10","author":"Carpentier","year":"2020","journal-title":"Sci. Rep."},{"issue":"5","key":"10.1016\/j.bios.2026.118565_bib2","doi-asserted-by":"crossref","first-page":"3253","DOI":"10.1021\/acs.analchem.7b04772","volume":"90","author":"Du","year":"2018","journal-title":"Anal. Chem."},{"issue":"15","key":"10.1016\/j.bios.2026.118565_bib3","doi-asserted-by":"crossref","DOI":"10.3390\/cancers14153758","volume":"14","author":"Gao","year":"2022","journal-title":"Cancers (Basel)"},{"issue":"6","key":"10.1016\/j.bios.2026.118565_bib4","doi-asserted-by":"crossref","first-page":"4598","DOI":"10.3892\/ol.2016.5287","volume":"12","author":"Hung","year":"2016","journal-title":"Oncol. Lett."},{"issue":"2","key":"10.1016\/j.bios.2026.118565_bib5","volume":"8","author":"Kaushik","year":"2019","journal-title":"Adv. Healthcare Mater."},{"issue":"48","key":"10.1016\/j.bios.2026.118565_bib6","volume":"30","author":"Lai Benjamin","year":"2020","journal-title":"Adv. Funct. Mater."},{"issue":"9","key":"10.1016\/j.bios.2026.118565_bib7","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22094322","volume":"22","author":"Lenin","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.bios.2026.118565_bib8","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1038\/s41563-021-01057-5","volume":"21","author":"LeSavage","year":"2022","journal-title":"Nat. Mater."},{"issue":"1","key":"10.1016\/j.bios.2026.118565_bib10","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1038\/s41392-024-01953-7","volume":"9","author":"Li","year":"2024","journal-title":"Signal Transduct. Targeted Ther."},{"issue":"4","key":"10.1016\/j.bios.2026.118565_bib9","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1039\/C8IB00019K","volume":"10","author":"Li","year":"2018","journal-title":"Integr. Biol."},{"key":"10.1016\/j.bios.2026.118565_bib12","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.omto.2023.04.007","volume":"29","author":"Lin","year":"2023","journal-title":"Mol. Ther. Oncolytics"},{"key":"10.1016\/j.bios.2026.118565_bib13","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1016\/j.copbio.2018.03.011","volume":"52","author":"Osaki","year":"2018","journal-title":"Curr. Opin. Biotechnol."},{"issue":"7","key":"10.1016\/j.bios.2026.118565_bib14","doi-asserted-by":"crossref","first-page":"7627","DOI":"10.1021\/acsnano.9b00686","volume":"13","author":"Paek","year":"2019","journal-title":"ACS Nano"},{"issue":"7825","key":"10.1016\/j.bios.2026.118565_bib15","doi-asserted-by":"crossref","first-page":"426","DOI":"10.1038\/s41586-020-2712-z","volume":"585","author":"Palikuqi","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.bios.2026.118565_bib16","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1146\/annurev-bioeng-090120-094330","volume":"23","author":"Shirure","year":"2021","journal-title":"Annu. Rev. Biomed. Eng."},{"issue":"9","key":"10.1016\/j.bios.2026.118565_bib17","doi-asserted-by":"crossref","first-page":"1190","DOI":"10.1016\/j.ccell.2021.07.020","volume":"39","author":"Veninga","year":"2021","journal-title":"Cancer Cell"},{"key":"10.1016\/j.bios.2026.118565_bib18","volume":"33","author":"Weng","year":"2025","journal-title":"Mater. Today Bio"},{"issue":"1","key":"10.1016\/j.bios.2026.118565_bib19","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1186\/s13046-020-01800-x","volume":"40","author":"Xie","year":"2021","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"10.1016\/j.bios.2026.118565_bib20","volume":"9","author":"Yang","year":"2021","journal-title":"Front. Cell Dev. Biol."},{"issue":"27","key":"10.1016\/j.bios.2026.118565_bib21","volume":"10","author":"Zou","year":"2023","journal-title":"Adv. Sci. (Weinh.)"}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566326001971?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566326001971?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T05:38:08Z","timestamp":1778564288000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566326001971"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,6]]},"references-count":20,"alternative-id":["S0956566326001971"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2026.118565","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2026,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"MASEA: A microfluidic system for in situ evaluation of tumor angiogenesis in PDO\u2013endothelial co-culture","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2026.118565","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"118565"}}