{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,15]],"date-time":"2026-10-15T03:16:41Z","timestamp":1792034201676,"version":"4.4.0"},"reference-count":37,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T00:00:00Z","timestamp":1782864000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T00:00:00Z","timestamp":1772409600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100024370","name":"Ministero dell'Istruzione dell'Universit\u00e0 e della Ricerca","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100024370","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2026,7]]},"DOI":"10.1016\/j.bios.2026.118567","type":"journal-article","created":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T00:36:25Z","timestamp":1772498185000},"page":"118567","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["An electrochemical enzyme-linked immunosorbent assay for interleukin 18 quantification in 3D skin models derived from ALS patients"],"prefix":"10.1016","volume":"303","author":[{"given":"Nicola","family":"Furlan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ugo","family":"D'Amora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ines","family":"Fasolino","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3367-5819","authenticated-orcid":false,"given":"Alessandro","family":"Silvestri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiara","family":"Zanardi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.bios.2026.118567_bib3","doi-asserted-by":"crossref","first-page":"620","DOI":"10.1016\/j.bios.2018.07.003","volume":"117","author":"Arya","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2026.118567_bib2","doi-asserted-by":"crossref","DOI":"10.3390\/s20102857","volume":"20","author":"Arya","year":"2020","journal-title":"Sensors"},{"key":"10.1016\/j.bios.2026.118567_bib4","doi-asserted-by":"crossref","first-page":"719","DOI":"10.1021\/bm7010906","volume":"9","author":"Batalla","year":"2008","journal-title":"Biomacromolecules"},{"key":"10.1016\/j.bios.2026.118567_bib5","doi-asserted-by":"crossref","first-page":"3754","DOI":"10.1002\/bit.28839","volume":"121","author":"Chen","year":"2024","journal-title":"Biotechnol. Bioeng."},{"key":"10.1016\/j.bios.2026.118567_bib6","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1002\/glia.23728","volume":"68","author":"Deora","year":"2020","journal-title":"Glia"},{"key":"10.1016\/j.bios.2026.118567_bib7","doi-asserted-by":"crossref","first-page":"240","DOI":"10.1021\/ja0170706","volume":"124","author":"Dequaire","year":"2002","journal-title":"J. Am. Chem. Soc."},{"key":"10.1016\/j.bios.2026.118567_bib8","doi-asserted-by":"crossref","first-page":"e645","DOI":"10.1212\/WNL.0000000000207479","volume":"101","author":"Downer","year":"2023","journal-title":"Neurology"},{"key":"10.1016\/j.bios.2026.118567_bib9","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1104\/pp.4.4.537","volume":"4","author":"Fong","year":"1929","journal-title":"Plant Physiol."},{"key":"10.1016\/j.bios.2026.118567_bib10","doi-asserted-by":"crossref","first-page":"2597","DOI":"10.1002\/celc.202100446","volume":"8","author":"H\u00f6fs","year":"2021","journal-title":"Chemelectrochem"},{"key":"10.1016\/j.bios.2026.118567_bib11","author":"Iannello"},{"key":"10.1016\/j.bios.2026.118567_bib12","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1186\/s13024-023-00685-6","volume":"19","author":"Irwin","year":"2024","journal-title":"Mol. Neurodegener."},{"key":"10.1016\/j.bios.2026.118567_bib13","volume":"1\u201328","author":"Jeevarathinam","year":"2025","journal-title":"Nat. Protoc."},{"key":"10.1016\/j.bios.2026.118567_bib14","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1006\/abio.1998.2961","volume":"267","author":"Lee","year":"1999","journal-title":"Anal. Biochem."},{"key":"10.1016\/j.bios.2026.118567_bib15","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2024.116040","volume":"250","author":"Lozano-Chamizo","year":"2024","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2026.118567_bib1","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1016\/j.electacta.2017.07.161","volume":"249","author":"\u00c1lvarez-Martos","year":"2017","journal-title":"Electrochim. Acta"},{"key":"10.1016\/j.bios.2026.118567_bib16","doi-asserted-by":"crossref","DOI":"10.1016\/j.envres.2022.114427","volume":"215","author":"Manoj","year":"2022","journal-title":"Environ. Res."},{"key":"10.1016\/j.bios.2026.118567_bib17","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1007\/s00604-021-05145-w","volume":"189","author":"Martins","year":"2021","journal-title":"Microchim. Acta"},{"key":"10.1016\/j.bios.2026.118567_bib18","doi-asserted-by":"crossref","first-page":"4736","DOI":"10.1039\/D4AN00392F","volume":"149","author":"Milne","year":"2024","journal-title":"Analyst"},{"key":"10.1016\/j.bios.2026.118567_bib19","doi-asserted-by":"crossref","first-page":"4446","DOI":"10.1021\/acs.langmuir.4c03620","article-title":"Facile antibody","volume":"41","author":"Monisha","year":"2025","journal-title":"Langmuir"},{"key":"10.1016\/j.bios.2026.118567_bib20","doi-asserted-by":"crossref","first-page":"1740","DOI":"10.1093\/brain\/awad426","volume":"147","author":"Nolano","year":"2024","journal-title":"Brain J. Neurol."},{"key":"10.1016\/j.bios.2026.118567_bib21","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1038\/s41565-019-0566-z","volume":"14","author":"Sabat\u00e9 del R\u00edo","year":"2019","journal-title":"Nat. Nanotechnol."},{"key":"10.1016\/j.bios.2026.118567_bib22","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1007\/s00604-024-06916-x","volume":"192","author":"Sajeevan","year":"2025","journal-title":"Microchim. Acta"},{"key":"10.1016\/j.bios.2026.118567_bib23","doi-asserted-by":"crossref","first-page":"10547","DOI":"10.1021\/acs.jpcb.6b07893","volume":"120","author":"Samiee","year":"2016","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.bios.2026.118567_bib24","doi-asserted-by":"crossref","unstructured":"Scarpa, E., D'Amora, U., De Cesare, N., Bonadies, I., Dubbioso, R., Nolano, M., Dardano, P., De Stefano, L., Fasolino, A., Zeppetelli, S., Silvestri, A., Zanardi, C., Milella, E., Fasolino, I. ACS Appl. Mater. Interfaces 2026. https:\/\/doi.org\/10.1021\/acsami.5c23366.","DOI":"10.1021\/acsami.5c23366"},{"key":"10.1016\/j.bios.2026.118567_bib25","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1002\/elan.201000419","volume":"23","author":"Seraf\u00edn","year":"2011","journal-title":"Electroanalysis"},{"key":"10.1016\/j.bios.2026.118567_bib26","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1042\/EBC20150002","volume":"60","author":"Sharma","year":"2016","journal-title":"Essays Biochem."},{"key":"10.1016\/j.bios.2026.118567_bib27","first-page":"7336","volume":"9","author":"Singh","year":"2024","journal-title":"ACS Omega"},{"key":"10.1016\/j.bios.2026.118567_bib28","series-title":"Cancer Cell Biology: Methods and Protocols","first-page":"115","author":"Tabatabaei","year":"2022"},{"key":"10.1016\/j.bios.2026.118567_bib29","doi-asserted-by":"crossref","first-page":"1969","DOI":"10.1021\/ac1026786","volume":"83","author":"Tajima","year":"2011","journal-title":"Anal. Chem."},{"key":"10.1016\/j.bios.2026.118567_bib30","doi-asserted-by":"crossref","first-page":"223","DOI":"10.1016\/j.msec.2016.08.075","volume":"70","author":"Thenmozhi","year":"2017","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.bios.2026.118567_bib31","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2024.110417","volume":"200","author":"Tian","year":"2024","journal-title":"Microchem. J."},{"key":"10.1016\/j.bios.2026.118567_bib32","volume":"11","author":"Timilsina","year":"2022","journal-title":"Adv. Healthcare Mater."},{"key":"10.1016\/j.bios.2026.118567_bib33","article-title":"Biomater","volume":"177","author":"Treccani","year":"2025","journal-title":"Adv"},{"key":"10.1016\/j.bios.2026.118567_bib34","doi-asserted-by":"crossref","first-page":"557","DOI":"10.1016\/j.snb.2009.07.025","volume":"141","author":"Upadhyay","year":"2009","journal-title":"Sens. Actuators, B Chem."},{"key":"10.1016\/j.bios.2026.118567_bib35","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.talanta.2009.03.010","volume":"79","author":"Upadhyay","year":"2009","journal-title":"Talanta"},{"key":"10.1016\/j.bios.2026.118567_bib36","doi-asserted-by":"crossref","first-page":"706","DOI":"10.1002\/elan.201900506","volume":"32","author":"Valverde","year":"2020","journal-title":"Electroanalysis"},{"key":"10.1016\/j.bios.2026.118567_bib37","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1016\/j.bios.2018.11.038","volume":"126","author":"Zhang","year":"2019","journal-title":"Biosens. Bioelectron."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566326001995?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566326001995?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T00:47:11Z","timestamp":1777596431000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566326001995"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7]]},"references-count":37,"alternative-id":["S0956566326001995"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2026.118567","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2026,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An electrochemical enzyme-linked immunosorbent assay for interleukin 18 quantification in 3D skin models derived from ALS patients","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2026.118567","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"118567"}}