{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T09:10:01Z","timestamp":1788685801006,"version":"build-2803163510"},"reference-count":45,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["62031022"],"award-info":[{"award-number":["62031022"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["51975400"],"award-info":[{"award-number":["51975400"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":[".62305394"],"award-info":[{"award-number":[".62305394"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013317","name":"Shanxi Provincial Key Research and Development Project","doi-asserted-by":"publisher","award":["202202010101004"],"award-info":[{"award-number":["202202010101004"]}],"id":[{"id":"10.13039\/501100013317","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100013317","name":"Shanxi Provincial Key Research and Development Project","doi-asserted-by":"publisher","award":["202102130501015"],"award-info":[{"award-number":["202102130501015"]}],"id":[{"id":"10.13039\/501100013317","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biosensors and Bioelectronics"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.bios.2026.118702","type":"journal-article","created":{"date-parts":[[2026,4,16]],"date-time":"2026-04-16T23:56:32Z","timestamp":1776383792000},"page":"118702","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Ultrasensitive cell surface stress biosensor based on magnetic-stress-electrical coupling"],"prefix":"10.1016","volume":"306","author":[{"given":"Haoyu","family":"Wang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong","family":"Zhao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sitong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingbo","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xing","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yang","family":"Ge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wang","family":"Ride","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4974-9306","authenticated-orcid":false,"given":"Shengbo","family":"Sang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"7","key":"10.1016\/j.bios.2026.118702_bib1","doi-asserted-by":"crossref","DOI":"10.1038\/s41551-023-01017-1","article-title":"High-throughput spatiotemporal monitoring of single-cell secretions via plasmonic microwell arrays","volume":"7","author":"Ansaryan","year":"2023","journal-title":"Nat. Biomed. Eng."},{"key":"10.1016\/j.bios.2026.118702_bib2","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2024.136697","article-title":"Magnetic anisotropic membrane-based mechanical biosensor for sensitization enhancement","volume":"422","author":"Bai","year":"2025","journal-title":"Sensor Actuat. B-Chem."},{"key":"10.1016\/j.bios.2026.118702_bib3","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2024.131630","article-title":"Atomic force microscopy investigation of DNA denaturation on a highly oriented pyrolytic graphite surface","volume":"267","author":"Barinov","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"issue":"5","key":"10.1016\/j.bios.2026.118702_bib4","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1007\/s10338-019-00113-7","article-title":"Measuring viscoelastic properties of living cells","volume":"32","author":"Bu","year":"2019","journal-title":"Acta Mech. Solida Sin."},{"key":"10.1016\/j.bios.2026.118702_bib5","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1016\/j.bios.2018.06.041","article-title":"A DNA nanostructured aptasensor for the sensitive electrochemical detection of HepG2 cells based on multibranched hybridization chain reaction amplification strategy","volume":"117","author":"Chen","year":"2018","journal-title":"Biosens. Bioelectron."},{"key":"10.1016\/j.bios.2026.118702_bib6","article-title":"An ultrahigh resolution pressure sensor based on percolative metal nanoparticle arrays","volume":"10","author":"Chen","year":"2019","journal-title":"Nat. Commun."},{"issue":"1","key":"10.1016\/j.bios.2026.118702_bib7","doi-asserted-by":"crossref","DOI":"10.1186\/s12951-024-02418-3","article-title":"Biointerfaces with ultrathin patterns for directional control of cell migration","volume":"22","author":"Cheng","year":"2024","journal-title":"J. Nanobiotechnol."},{"issue":"1","key":"10.1016\/j.bios.2026.118702_bib8","doi-asserted-by":"crossref","DOI":"10.1038\/s41378-023-00559-3","article-title":"Rapid prototyping of a polymer MEMS droplet dispenser by laser-assisted 3D printing","volume":"9","author":"Courson","year":"2023","journal-title":"Microsyst. Nanoeng."},{"issue":"7","key":"10.1016\/j.bios.2026.118702_bib9","doi-asserted-by":"crossref","DOI":"10.1016\/j.drudis.2024.103981","article-title":"Peptide-functionalized, -assembled and - loaded nanoparticles in cancer therapy","volume":"29","author":"Dai","year":"2024","journal-title":"Drug Discov. Today"},{"issue":"4","key":"10.1016\/j.bios.2026.118702_bib10","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1016\/j.annonc.2023.12.008","article-title":"Nivolumab in sorafenib-naive and sorafenib-experienced patients with advanced hepatocellular carcinoma: 5-year follow-up from CheckMate 040","volume":"35","author":"El-Khoueiry","year":"2024","journal-title":"Ann. Oncol."},{"issue":"3","key":"10.1016\/j.bios.2026.118702_bib11","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/j.pmatsci.2007.09.001","article-title":"On the role of surface energy and surface stress in phase-transforming nanoparticles","volume":"53","author":"Fischer","year":"2008","journal-title":"Prog. Mater. Sci."},{"key":"10.1016\/j.bios.2026.118702_bib12","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.pmatsci.2017.04.006","article-title":"Advances in piezoelectric thin films for acoustic biosensors, acoustofluidics and lab-on-chip applications","volume":"89","author":"Fu","year":"2017","journal-title":"Prog. Mater. Sci."},{"issue":"3","key":"10.1016\/j.bios.2026.118702_bib13","article-title":"Development of a new lab-on-paper microfluidics platform using Bi-Material cantilever actuators for ELISA on paper","volume":"13","author":"Heidari-Bafroui","year":"2023","journal-title":"Biosensors (Basel)"},{"issue":"11","key":"10.1016\/j.bios.2026.118702_bib14","doi-asserted-by":"crossref","first-page":"1189","DOI":"10.2116\/analsci.32.1189","article-title":"Finite element analysis on nanomechanical sensing of cellular forces","volume":"32","author":"Imamura","year":"2016","journal-title":"Anal. Sci."},{"issue":"2","key":"10.1016\/j.bios.2026.118702_bib15","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1021\/acs.nanolett.2c04198","article-title":"Tailoring the sensitivity of microcantilevers to monitor the mass of single adherent living cells","volume":"23","author":"Incaviglia","year":"2023","journal-title":"Nano Lett."},{"issue":"2","key":"10.1016\/j.bios.2026.118702_bib16","article-title":"RGD peptide in cancer targeting: benefits, challenges, solutions, and possible integrin-RGD interactions","volume":"13","author":"Javid","year":"2024","journal-title":"Cancer Med. US"},{"issue":"1","key":"10.1016\/j.bios.2026.118702_bib18","doi-asserted-by":"crossref","DOI":"10.1186\/s13046-024-03061-4","article-title":"PLAG1 interacts with GPX4 to conquer vulnerability to sorafenib induced ferroptosis through a PVT1\/miR-195-5p axis-dependent manner in hepatocellular carcinoma","volume":"43","author":"Li","year":"2024","journal-title":"J. Exp. Clin. Cancer Res."},{"key":"10.1016\/j.bios.2026.118702_bib19","doi-asserted-by":"crossref","DOI":"10.1016\/j.bios.2024.116008","article-title":"The luminescent principle and sensing mechanism of metal-organic framework for bioanalysis and bioimaging","volume":"249","author":"Li","year":"2024","journal-title":"Biosens. Bioelectron."},{"issue":"12","key":"10.1016\/j.bios.2026.118702_bib17","doi-asserted-by":"crossref","first-page":"1458","DOI":"10.1038\/s41589-023-01353-y","article-title":"Polarized focal adhesion kinase activity within a focal adhesion during cell migration","volume":"19","author":"Li","year":"2023","journal-title":"Nat. Chem. Biol."},{"issue":"1","key":"10.1016\/j.bios.2026.118702_bib20","doi-asserted-by":"crossref","DOI":"10.1007\/s42114-022-00599-9","article-title":"Neuromorphic properties of flexible carbon nanotube\/polydimethylsiloxane nanocomposites","volume":"6","author":"Liu","year":"2023","journal-title":"Adv. Compos. Hybrid Mater."},{"issue":"8","key":"10.1016\/j.bios.2026.118702_bib21","doi-asserted-by":"crossref","first-page":"6477","DOI":"10.1021\/acsnano.3c11994","article-title":"High-sensitivity optical sensors empowered by quasi-bound states in the continuum in a hybrid metal-dielectric metasurface","volume":"18","author":"Luo","year":"2024","journal-title":"ACS Nano"},{"key":"10.1016\/j.bios.2026.118702_bib22","doi-asserted-by":"crossref","DOI":"10.1016\/j.ccr.2024.216102","article-title":"Metal-organic frameworks (MOFs) and MOF composites based biosensors","volume":"519","author":"Mohanty","year":"2024","journal-title":"Coord. Chem. Rev."},{"issue":"8","key":"10.1016\/j.bios.2026.118702_bib23","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.201901454","article-title":"(De)form and function: measuring cellular forces with deformable materials and deformable structures","volume":"9","author":"Obenaus","year":"2020","journal-title":"Adv. Healthcare Mater."},{"issue":"19","key":"10.1016\/j.bios.2026.118702_bib24","doi-asserted-by":"crossref","first-page":"4481","DOI":"10.7150\/jca.32985","article-title":"Regional biomechanical imaging of liver cancer cells","volume":"10","author":"Pei","year":"2019","journal-title":"J. Cancer"},{"issue":"5","key":"10.1016\/j.bios.2026.118702_bib25","doi-asserted-by":"crossref","DOI":"10.3390\/cancers16050901","article-title":"Hepatocellular carcinoma: old and emerging therapeutic targets","volume":"16","author":"Pessino","year":"2024","journal-title":"Cancers"},{"key":"10.1016\/j.bios.2026.118702_bib26","doi-asserted-by":"crossref","DOI":"10.1016\/j.msec.2020.111087","article-title":"A new way to prepare gold nanoparticles by sputtering - sterilization, stability and other properties","volume":"115","author":"Pislov\u00e1","year":"2020","journal-title":"Mat. Sci. Eng. C-Mater."},{"key":"10.1016\/j.bios.2026.118702_bib29","doi-asserted-by":"crossref","DOI":"10.1016\/j.snb.2022.133209","article-title":"Magneto-stress-electric-coupled biosensors originated in magnetostrictive effect for sensitization","volume":"378","author":"Sang","year":"2023","journal-title":"Sensor Actuat. B-Chem."},{"issue":"1","key":"10.1016\/j.bios.2026.118702_bib30","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1021\/acssensors.3c02171","article-title":"Magneto-mechanical coupling study of magnetorheological elastomer thin films for sensitivity enhancement","volume":"9","author":"Sang","year":"2024","journal-title":"ACS Sens."},{"key":"10.1016\/j.bios.2026.118702_bib28","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.bios.2015.06.035","article-title":"Surface stress-based biosensors (vol 51, pg 124, 2014)","volume":"73","author":"Sang","year":"2015","journal-title":"Biosens. Bioelectron."},{"issue":"11","key":"10.1016\/j.bios.2026.118702_bib27","doi-asserted-by":"crossref","first-page":"2420","DOI":"10.1016\/j.bios.2010.03.035","article-title":"A novel PDMS micro membrane biosensor based on the analysis of surface stress","volume":"25","author":"Sang","year":"2010","journal-title":"Biosens. Bioelectron."},{"issue":"4","key":"10.1016\/j.bios.2026.118702_bib31","doi-asserted-by":"crossref","first-page":"2120","DOI":"10.1021\/acsaelm.3c01732","article-title":"Membrane-based NEMS\/MEMS biosensors","volume":"6","author":"Stapf","year":"2024","journal-title":"ACS Appl. Electron Mater."},{"issue":"23","key":"10.1016\/j.bios.2026.118702_bib32","doi-asserted-by":"crossref","first-page":"26332","DOI":"10.1021\/acsanm.3c04645","article-title":"Choline carboxylic acid ionic liquid-stabilized anisotropic gold nanoparticles for photothermal therapy","volume":"7","author":"Vashisth","year":"2024","journal-title":"ACS Appl. Nano Mater."},{"key":"10.1016\/j.bios.2026.118702_bib33","doi-asserted-by":"crossref","DOI":"10.1016\/j.energy.2023.126896","article-title":"Structure optimization and performance of piezoelectric energy harvester for improving road power generation effect","volume":"270","author":"Wang","year":"2023","journal-title":"Energy"},{"issue":"3","key":"10.1016\/j.bios.2026.118702_bib34","doi-asserted-by":"crossref","first-page":"3423","DOI":"10.1021\/acsomega.2c07338","article-title":"Multilayer heterogeneous membrane biosensor based on multiphysical field coupling for human serum albumin detection","volume":"8","author":"Wang","year":"2023","journal-title":"ACS Omega"},{"key":"10.1016\/j.bios.2026.118702_bib36","article-title":"Multifunctional terahertz biodetection enabled by resonant metasurfaces","author":"Wang","year":"2025","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bios.2026.118702_bib35","article-title":"Ultrasensitive terahertz label-free metasensors enabled by quasi-bound states in the continuum","volume":"7","author":"Wang","year":"2024","journal-title":"Research-China"},{"issue":"3","key":"10.1016\/j.bios.2026.118702_bib37","doi-asserted-by":"crossref","first-page":"1155","DOI":"10.1021\/jacsau.4c00002","article-title":"High dynamic range probing of single-molecule mechanical force transitions at cell\u2013matrix adhesion bonds by a plasmonic tension nanosensor","volume":"4","author":"Wu","year":"2024","journal-title":"JACS Au"},{"key":"10.1016\/j.bios.2026.118702_bib38","doi-asserted-by":"crossref","DOI":"10.1016\/j.bej.2022.108361","article-title":"A membrane-type mechanical biosensor based on magnetic, surface stress and electric coupling enhancement for HSA detection","volume":"180","author":"Xiao","year":"2022","journal-title":"Biochem. Eng. J."},{"issue":"20","key":"10.1016\/j.bios.2026.118702_bib39","doi-asserted-by":"crossref","DOI":"10.1002\/advs.202200507","article-title":"High-performance flexible pressure sensor with a self-healing function for tactile feedback","volume":"9","author":"Yang","year":"2022","journal-title":"Adv. Sci."},{"issue":"22","key":"10.1016\/j.bios.2026.118702_bib42","doi-asserted-by":"crossref","first-page":"31357","DOI":"10.1016\/j.ceramint.2021.08.009","article-title":"Structure, electrical, optical and magnetoelectric properties of magnetron sputtered nanocrystalline NiFe\/BaTiO thin films","volume":"47","author":"Zhang","year":"2021","journal-title":"Ceram. Int."},{"issue":"1","key":"10.1016\/j.bios.2026.118702_bib44","doi-asserted-by":"crossref","DOI":"10.1002\/adma.202411490","article-title":"Deep-learning empowered customized chiral metasurface for calibration-free biosensing","volume":"37","author":"Zhang","year":"2025","journal-title":"Adv. Mater."},{"key":"10.1016\/j.bios.2026.118702_bib43","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.jiec.2022.10.012","article-title":"A magnetostrictive self-powered biosensor based on au-batio-fega & PDMS","volume":"117","author":"Zhang","year":"2023","journal-title":"J. Ind. Eng. Chem."},{"issue":"40","key":"10.1016\/j.bios.2026.118702_bib46","doi-asserted-by":"crossref","first-page":"9658","DOI":"10.1039\/D3TB01268A","article-title":"A mechanical biosensor based on membrane-mediated magneto-stress-electric coupled sensitization for human serum albumin detection","volume":"11","author":"Zhao","year":"2023","journal-title":"J. Mater. Chem. B"},{"issue":"11","key":"10.1016\/j.bios.2026.118702_bib45","doi-asserted-by":"crossref","first-page":"6274","DOI":"10.1021\/acsbiomaterials.9b01073","article-title":"Sandwich-type surface stress biosensor based on self-assembled gold nanoparticles in PDMS film for BSA detection","volume":"5","author":"Zhao","year":"2019","journal-title":"ACS Biomater. Sci. Eng."},{"issue":"10","key":"10.1016\/j.bios.2026.118702_bib48","doi-asserted-by":"crossref","first-page":"2980","DOI":"10.1021\/acs.nanolett.3c03781","article-title":"An optical fiber-based nanomotion sensor for rapid antibiotic and antifungal susceptibility tests","volume":"24","author":"Zhou","year":"2024","journal-title":"Nano Lett."}],"container-title":["Biosensors and Bioelectronics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566326003349?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0956566326003349?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,6]],"date-time":"2026-09-06T08:11:51Z","timestamp":1788682311000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0956566326003349"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":45,"alternative-id":["S0956566326003349"],"URL":"https:\/\/doi.org\/10.1016\/j.bios.2026.118702","relation":{},"ISSN":["0956-5663"],"issn-type":[{"value":"0956-5663","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ultrasensitive cell surface stress biosensor based on magnetic-stress-electrical coupling","name":"articletitle","label":"Article Title"},{"value":"Biosensors and Bioelectronics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bios.2026.118702","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier B.V. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"118702"}}