{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,7]],"date-time":"2026-08-07T15:51:46Z","timestamp":1786117906073,"version":"build-2736575974"},"reference-count":26,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T00:00:00Z","timestamp":1783728000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["BioSystems"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.biosystems.2026.105888","type":"journal-article","created":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T06:35:30Z","timestamp":1783751730000},"page":"105888","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Cold-selective topological bias and the emergence of the first membranes"],"prefix":"10.1016","volume":"267","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2691-5589","authenticated-orcid":false,"given":"S. Hussain","family":"Ather","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard","family":"Gordon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biosystems.2026.105888_bib1","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1038\/ncomms1076","article-title":"In-ice evolution of RNA polymerase ribozyme activity","volume":"1","author":"Attwater","year":"2010","journal-title":"Nat. Commun."},{"key":"10.1016\/j.biosystems.2026.105888_bib2","first-page":"376","article-title":"A theorem on trees","volume":"23","author":"Cayley","year":"1889","journal-title":"Quarterly Journal of Pure and Applied Mathematics"},{"key":"10.1016\/j.biosystems.2026.105888_bib3","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1126\/science.1100757","article-title":"The emergence of competition between model protocells","volume":"305","author":"Chen","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.biosystems.2026.105888_bib4","first-page":"1087","article-title":"Amino acids in meteorites","volume":"19","author":"Cronin","year":"1997","journal-title":"Adv. Space Res."},{"key":"10.1016\/j.biosystems.2026.105888_bib5","first-page":"36","article-title":"Where did life begin? Testing ideas in prebiotic analogue conditions","volume":"7","author":"Deamer","year":"2017","journal-title":"Life"},{"key":"10.1016\/j.biosystems.2026.105888_bib6","article-title":"Chemistry and physics of primitive membranes","author":"Deamer","year":"2005","journal-title":"Cold Spring Harbor Perspect. Biol."},{"key":"10.1016\/j.biosystems.2026.105888_bib7","doi-asserted-by":"crossref","DOI":"10.1063\/1.4818538","article-title":"Statistical physics of self-replication","volume":"139","author":"England","year":"2013","journal-title":"J. Chem. Phys."},{"key":"10.1016\/j.biosystems.2026.105888_bib8","series-title":"Origin of Life via Archaea: Shaped Droplets to Archaea First, with a Compendium of Archaea Micrographs","author":"Gordon","year":"2024"},{"key":"10.1016\/j.biosystems.2026.105888_bib9","series-title":"Conflicting Models for the Origin of Life","article-title":"Ow to make a transmembrane domain at the origin of life: a possible origin of proteins","author":"Gordon","year":"2023"},{"key":"10.1016\/j.biosystems.2026.105888_bib10","doi-asserted-by":"crossref","first-page":"618","DOI":"10.1126\/science.1089904","article-title":"Experimental models of primitive cellular compartments","author":"Hanczyc","year":"2003","journal-title":"Science"},{"key":"10.1016\/j.biosystems.2026.105888_bib11","series-title":"Thermal Biophysics of Membranes","author":"Heimburg","year":"2007"},{"key":"10.1016\/j.biosystems.2026.105888_bib12","article-title":"Elastic properties of lipid bilayers: theory and possible experiments","volume":"28","author":"Helfrich","year":"1973","journal-title":"Z. Naturforsch. C Biosci."},{"key":"10.1016\/j.biosystems.2026.105888_bib13","article-title":"Compounds-specific \u03b413C analyses of individual carboxylic acids in the murchison meteorite","volume":"29","author":"Hiroshi Naraoka","year":"1999","journal-title":"Orig. Life Evol. Biosph."},{"key":"10.1016\/j.biosystems.2026.105888_bib14","doi-asserted-by":"crossref","DOI":"10.1039\/f29767201525","article-title":"Theory of self-assembly of lipid bilayers and micelles","author":"Israelachvili","year":"1976","journal-title":"J. Chem. Soc., Faraday Trans. 1: Physical Chemistry in Condensed Phases"},{"issue":"3","key":"10.1016\/j.biosystems.2026.105888_bib15","doi-asserted-by":"crossref","first-page":"401","DOI":"10.1016\/S0304-4157(98)00017-3","article-title":"Hydrophobic mismatch between proteins and lipids in membranes","volume":"1376","author":"Killian","year":"1998","journal-title":"Biochim. Biophys. Acta - Biomembr."},{"key":"10.1016\/j.biosystems.2026.105888_bib16","series-title":"The Aqueous Phase Behavior of Surfactants","author":"Laughlin","year":"1994"},{"key":"10.1016\/j.biosystems.2026.105888_bib17","doi-asserted-by":"crossref","first-page":"7812","DOI":"10.1021\/jp071097f","article-title":"The MARTINI force field: coarse grained model for biomolecular simulations","volume":"111","author":"Marrink","year":"2007","journal-title":"J. Phys. Chem. B"},{"key":"10.1016\/j.biosystems.2026.105888_bib18","doi-asserted-by":"crossref","DOI":"10.1016\/S0304-4157(00)00016-2","article-title":"Structure of lipid bilayers","author":"Nagle","year":"2000","journal-title":"Biochim. Biophys. Acta"},{"key":"10.1016\/j.biosystems.2026.105888_bib19","article-title":"From decanoate micelles to decanoic acid\/decanoate vesicles","author":"Namani","year":"2008","journal-title":"Langmuir"},{"key":"10.1016\/j.biosystems.2026.105888_bib20","doi-asserted-by":"crossref","DOI":"10.1039\/b103775g","article-title":"Organic compounds in carbonaceous meteorites","author":"Sephton","year":"2002","journal-title":"Nat. Prod. Rep."},{"key":"10.1016\/j.biosystems.2026.105888_bib21","article-title":"Lipid formation by aqueous Fischer\u2013tropsch-type synthesis over a temperature range of 100 to 400\u00b0C","volume":"31","author":"Simoneit","year":"2001","journal-title":"Orig. Life Evol. Biosph."},{"key":"10.1016\/j.biosystems.2026.105888_bib22","series-title":"The Physical Chemistry of Lipids: from Alkanes to Phospholipids","author":"Small","year":"1986"},{"key":"10.1016\/j.biosystems.2026.105888_bib23","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1038\/s41592-021-01098-3","article-title":"Martini 3: a general purpose force field for coarse-grained molecular dynamics","volume":"18","author":"Souza","year":"2021","journal-title":"Nat. Methods"},{"key":"10.1016\/j.biosystems.2026.105888_bib24","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1038\/35053176","article-title":"Synthesizing life","volume":"409","author":"Szostak","year":"2001","journal-title":"Nature"},{"key":"10.1016\/j.biosystems.2026.105888_bib25","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1023\/A:1006592502746","article-title":"Lipid synthesis under hydrothermal conditions by fischer-tropsch-type reactions","volume":"29","author":"Thomas","year":"1999","journal-title":"Orig. Life Evol. Biosph."},{"key":"10.1016\/j.biosystems.2026.105888_bib26","article-title":"Formation and properties of fatty acid vesicles","volume":"11","author":"Walde","year":"2006","journal-title":"Curr. Opin. Colloid Interface Sci."}],"container-title":["BioSystems"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030326472600198X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S030326472600198X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,6]],"date-time":"2026-08-06T14:42:45Z","timestamp":1786027365000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S030326472600198X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":26,"alternative-id":["S030326472600198X"],"URL":"https:\/\/doi.org\/10.1016\/j.biosystems.2026.105888","relation":{},"ISSN":["0303-2647"],"issn-type":[{"value":"0303-2647","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cold-selective topological bias and the emergence of the first membranes","name":"articletitle","label":"Article Title"},{"value":"BioSystems","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biosystems.2026.105888","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"105888"}}