{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T10:39:43Z","timestamp":1791196783408,"version":"4.1.0"},"reference-count":166,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Biotechnology Advances"],"published-print":{"date-parts":[[2007,1]]},"DOI":"10.1016\/j.biotechadv.2006.08.003","type":"journal-article","created":{"date-parts":[[2006,8,31]],"date-time":"2006-08-31T12:49:18Z","timestamp":1157028558000},"page":"13-44","source":"Crossref","is-referenced-by-count":59,"title":["Molecular targets for detection and immunotherapy in Cryptosporidium parvum"],"prefix":"10.1016","volume":"25","author":[{"given":"Jeanine I.","family":"Boulter-Bitzer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jack T.","family":"Trevors","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biotechadv.2006.08.003_bib1","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1126\/science.1094786","article-title":"Complete genome sequence of the apicomplexan, Cryptosporidium parvum","volume":"304","author":"Abrahamsen","year":"2004","journal-title":"Science"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib2","doi-asserted-by":"crossref","first-page":"2770","DOI":"10.1128\/JCM.28.12.2770-2774.1990","article-title":"Detection of Cryptosporidium parvum oocysts in bovine feces by monoclonal antibody capture enzyme-linked immunosorbent assay","volume":"28","author":"Anusz","year":"1990","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib3","series-title":"Cryptosporidium and cryptosporidiosis","first-page":"251","article-title":"Diagnosis","author":"Arrowood","year":"1997"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib4","doi-asserted-by":"crossref","first-page":"2283","DOI":"10.1128\/IAI.57.8.2283-2288.1989","article-title":"Effects of immune colostrum and orally administered antisporozoite monoclonal antibodies on the outcome of Cryptosporidium parvum infections in noenatal mice","volume":"57","author":"Arrowood","year":"1989","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib5","doi-asserted-by":"crossref","first-page":"315","DOI":"10.2307\/3283104","article-title":"Immunofluorescent microscopial visualization of trails left by gliding Cryptosporidium parvum sporozoites","volume":"77","author":"Arrowood","year":"1991","journal-title":"J Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib6","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0166-6851(98)00119-4","article-title":"A novel multi-domain mucin-like glycoprotein of Cryptosporidium parvum mediates invasion","volume":"96","author":"Barnes","year":"1998","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib7","doi-asserted-by":"crossref","first-page":"298","DOI":"10.4049\/jimmunol.145.1.298","article-title":"Cryptosporidium parvum merozoites share neutralization-sensitive epitopes with sporozoites","volume":"145","author":"Bjorneby","year":"1990","journal-title":"J Immunol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib8","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1006\/expr.2000.4545","article-title":"A 23-kDa recombinant antigen of Cryptosporidium parvum induces a cellular immune response on in vitro stimulated spleen and mesenteric lymph node cells from infected mice","volume":"96","author":"Bonafonte","year":"2000","journal-title":"Exp Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib9","doi-asserted-by":"crossref","first-page":"1703","DOI":"10.1128\/IAI.59.5.1703-1708.1991","article-title":"Characterization of microneme antigens of Cryptosporidium parvum (Protozoa Apicomplexa)","volume":"59","author":"Bonnin","year":"1991","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib10","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/BF00931211","article-title":"A new antigen of Cryptosporidium parvum micronemes possessing epitopes cross-reactive with macrogamete granules","volume":"79","author":"Bonnin","year":"1993","journal-title":"Parasitol Res"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib11","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1007\/s004360100424","article-title":"Characterization of a monoclonal antibody reacting with antigen-4 domain of gp900 in Cryptosporidium parvum invasive stages","volume":"87","author":"Bonnin","year":"2001","journal-title":"Parasitol Res"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib12","first-page":"185","article-title":"Molecular epidemiology of human cryptosporidiosis","volume":"47","author":"Caccio","year":"2005","journal-title":"Parassitologia"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib13","doi-asserted-by":"crossref","first-page":"818","DOI":"10.1016\/j.watres.2003.10.012","article-title":"Biology, persistence, and detection of Cryptosporidium parvum and Cryptosporidium hominis oocyst","volume":"38","author":"Carey","year":"2004","journal-title":"Water Res"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib14","doi-asserted-by":"crossref","first-page":"5167","DOI":"10.1128\/IAI.68.9.5167-5175.2000","article-title":"Mediation of Cryptosporidium parvum infection in vitro by mucin-like glycoproteins defined by a neutralizing monoclonal antibody","volume":"68","author":"Cevallos","year":"2000","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib15","doi-asserted-by":"crossref","first-page":"4108","DOI":"10.1128\/IAI.68.7.4108-4116.2000","article-title":"Molecular cloning and expression of a gene encoding Cryptosporidium parvum glycoproteins gp40 and gp15","volume":"68","author":"Cevallos","year":"2000","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib16","doi-asserted-by":"crossref","first-page":"157","DOI":"10.4269\/ajtmh.1999.60.157","article-title":"Infectibity of Cryptosporidium parvum in healthy adults with pre-existing anti-C. parvum serum immunoglobulin","volume":"60","author":"Chappel","year":"1999","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib19","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/S0016-5085(00)70219-8","article-title":"Mechanisms of attachment and internalization of Cryptosporidium parvum to biliary and intestinal epithelial cells","volume":"118","author":"Chen","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib18","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1056\/NEJMra013170","article-title":"Cryptosporidioisis","volume":"346","author":"Chen","year":"2002","journal-title":"N Engl J Med"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib17","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0020-7519(02)00282-5","article-title":"Polyclonal Fab phage display libraries with a high percentage of diverse clones to Cryptosporidium parvum glycoproteins","volume":"33","author":"Chen","year":"2003","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib20","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1016\/S0065-308X(08)60119-0","article-title":"Antibody-based immunotherapy of cryptosporidiosis","volume":"40","author":"Crabb","year":"1998","journal-title":"Adv Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib21","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1080\/10643388609388328","article-title":"Cryptosporidium: its biology and potential for environmental transmission","volume":"17","author":"Current","year":"1986","journal-title":"CRC Crit Rev Environ Control"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib22","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/S0923-2494(98)80010-2","article-title":"The next generation of antibodies: production of recombinant antibodies or fragments derived thereof","volume":"149","author":"de Geus","year":"1998","journal-title":"Res Immunol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib23","doi-asserted-by":"crossref","first-page":"6987","DOI":"10.1128\/IAI.70.12.6987-6995.2002","article-title":"Cryptosporidium parvum genes containing thrombospondin type 1 domains","volume":"70","author":"Deng","year":"2002","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib24","doi-asserted-by":"crossref","first-page":"4079","DOI":"10.1128\/IAI.61.10.4079-4084.1993","article-title":"Anti-Cryptosporidium antibodies inhibit infectivity in vitro and in vivo","volume":"61","author":"Doyle","year":"1993","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib25","doi-asserted-by":"crossref","first-page":"1007","DOI":"10.1016\/S0020-7519(98)00076-9","article-title":"Apical organelles and host-cell invasion by Apicomplexa","volume":"28","author":"Dubremetz","year":"1998","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib26","series-title":"Cryptosporidiosis of man and animals","author":"Duby","year":"1990"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib27","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1056\/NEJM199503303321304","article-title":"The infectivity of Cryptosporidium parvum in healthy volunteers","volume":"332","author":"DuPont","year":"1995","journal-title":"N Engl J Med"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib28","series-title":"Waterbourne pathogens","author":"Edge","year":"2003"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib29","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1051\/parasite\/2004112225","article-title":"Immunolocalization of an enterotoxic glycoprotein exoantigen on the secretory organelles of Cryptosporidium parvum sporozoites","volume":"11","author":"El-Suewy","year":"2004","journal-title":"Parasite"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib30","doi-asserted-by":"crossref","first-page":"4469","DOI":"10.1128\/IAI.66.9.4469-4473.1998","article-title":"Role of immunoglobulin A monoclonal antibodies against P23 in controlling murine Cryptosporidium parvum infection","volume":"66","author":"Enriquez","year":"1998","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib36","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1128\/MMBR.50.4.458-483.1986","article-title":"Cryptosporidium spp. and cryptosporidiosis","volume":"50","author":"Fayer","year":"1986","journal-title":"Microbiol Rev"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib31","doi-asserted-by":"crossref","first-page":"393","DOI":"10.2307\/3282595","article-title":"Efficacy of hyperimmune bovine colostrum for prophylaxis of cryptosporidiosis in neonatal calves","volume":"75","author":"Fayer","year":"1989","journal-title":"J Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib34","doi-asserted-by":"crossref","first-page":"151","DOI":"10.2307\/3282956","article-title":"Hyperimmune bovine colostrum neutralizes Cryptosporidium sporozoites and protects mice against oocyst challenge","volume":"75","author":"Fayer","year":"1989","journal-title":"J Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib32","doi-asserted-by":"crossref","first-page":"2962","DOI":"10.1128\/IAI.58.9.2962-2965.1990","article-title":"Immunotherapeutic efficacy of bovine clostral immunoglobulin from a hyperimmunised cow against cryptosporidiosis in neonatal mice","volume":"58","author":"Fayer","year":"1990","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib35","series-title":"Cryptosporidium and Cryptosporidiosis","first-page":"251","article-title":"The general biology of Cryptosporidium","author":"Fayer","year":"1997"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib33","doi-asserted-by":"crossref","first-page":"1305","DOI":"10.1016\/S0020-7519(00)00135-1","article-title":"Epidemology of Cryptosporidium: transmission, detection and identification","volume":"30","author":"Fayer","year":"2000","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib37","series-title":"96th general meeting of the American society of microbiology: Abstracts","first-page":"371","article-title":"Milk antibodies against purified colonization factor antigens are protective in a human enterotoxigenic Escherichia coli challenge study","author":"Freedman","year":"1996"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib38","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1084\/jem.177.5.1287","article-title":"Malaria circumsporozoite protein binds to heparin sulfate proteoglycans associated with the surface membrane of hepatocytes","volume":"177","author":"Frevert","year":"1993","journal-title":"J Exp Med"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib40","doi-asserted-by":"crossref","first-page":"4008","DOI":"10.1128\/IAI.66.8.4008-4009.1998","article-title":"Serologic response to human Cryptosporidium infections","volume":"66","author":"Frost","year":"1998","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib42","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1002\/j.1551-8833.1997.tb08330.x","article-title":"So many oocysts, so few outbreaks","volume":"89","author":"Frost","year":"1997","journal-title":"J Am Waterworks Assoc"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib39","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1017\/S095026889800898X","article-title":"A two-year follow-up survey of antibody to Cryptosporidium in Jackson county, Oregon following an outbreak of waterborne disease","volume":"212","author":"Frost","year":"1998","journal-title":"Epidemiol Infect"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib41","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1093\/ije\/29.2.376","article-title":"Serological analysis of a cryptosporidiosis epidemic","volume":"29","author":"Frost","year":"2000","journal-title":"Int J Epidemiol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib43","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1086\/427561","article-title":"How clean must our drinking water be: the importance of protective immunity","volume":"191","author":"Frost","year":"2005","journal-title":"J Infect Dis"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib44","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1097\/00042560-199612010-00008","article-title":"Treatment of severe diarrhea caused by Cryptosporidium parvum with oral bovine immunoglobulin concentrate in patients with AIDS","volume":"13","author":"Greenberg","year":"1996","journal-title":"J Acquir Immune Defic Syndr Human Retrovirol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib45","first-page":"42S","article-title":"Cryptosporidium parvum sporozoites deposit trails of 11A5 antigen during gliding locomotion and shed 11A5 antigen during invasion of MDCK dells in vitro","volume":"41","author":"Gut","year":"1994","journal-title":"J Eukaryot Microbiol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib46","doi-asserted-by":"crossref","first-page":"2208","DOI":"10.1128\/IAI.62.6.2208-2213.1994","article-title":"Attachment of Cryptosporidium parvum sporozoites to MDCK cells in vitro","volume":"62","author":"Hammer","year":"1994","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib47","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1089\/104454904323090967","article-title":"The humoral and cellular immune responses in mice induced by DNA vaccine expressing the sporozoite surface protein of Cryptosporidium parvum","volume":"23","author":"He","year":"2004","journal-title":"DNA Cell Biol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib48","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1016\/S0020-7519(01)00212-0","article-title":"Complete development and long-term maintenance of Cryptosporidium parvum human and cattle genotypes in cell culture","volume":"31","author":"Hijjawi","year":"2001","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib49","doi-asserted-by":"crossref","first-page":"1719","DOI":"10.1016\/S0020-7519(02)00199-6","article-title":"Successful in vitro cultivation of Cryptosporidium andersoni: evidence for the existence of novel extracellular stages in the life cycle and implications for the classification of Cryptosporidium","volume":"32","author":"Hijjawi","year":"2002","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib50","doi-asserted-by":"crossref","first-page":"212","DOI":"10.1645\/GE-3204","article-title":"Cryptosporidium parvum attachment to and internalization by human biliary epithelia in vitro: a morphologic study","volume":"90","author":"Huang","year":"2004","journal-title":"J Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib51","doi-asserted-by":"crossref","first-page":"504","DOI":"10.1086\/422649","article-title":"Health sequelae of human cryptosporidiosis in immunocompetent patients","volume":"39","author":"Hunter","year":"2004","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib52","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.3201\/eid1007.030582","article-title":"Sporadic cryptosporidiosis case-control study with genotyping","volume":"10","author":"Hunter","year":"2004","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib53","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1016\/0166-6851(95)00050-B","article-title":"Cloning and expression of cDNA encoding an antigenic Cryptosporidium parvum protein","volume":"71","author":"Jenkins","year":"1995","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib54","doi-asserted-by":"crossref","first-page":"2377","DOI":"10.1128\/IAI.61.6.2377-2382.1993","article-title":"Cloning and expression of a cDNA encoding epitopes shared by 15- and 60-kilodalton proteins of Cryptosporidium parvum sporozoites","volume":"61","author":"Jenkins","year":"1993","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib55","doi-asserted-by":"crossref","first-page":"2453","DOI":"10.1016\/S0264-410X(98)00369-7","article-title":"Hyperimmune bovine colostrum specific for recombinant Cryptosporidium parvum antigen confers partial protection against cryptosporidiosis in immunosuppressed adult mice","volume":"17","author":"Jenkins","year":"1999","journal-title":"Vaccine"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib56","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1128\/CDLI.6.6.912-920.1999","article-title":"Cloning and expression of a DNA sequence encoding a 41-kilodalton Cryptosporidium parvum oocyst wall protein","volume":"6","author":"Jenkins","year":"1999","journal-title":"Clin Diagn Lab Immunol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib57","first-page":"44S","article-title":"Role of a Gal\/GalNAc-specific sporozoite surface lectin in Cryptosporidium parvum-host cell interaction","volume":"41","author":"Joe","year":"1994","journal-title":"J Eukaryot Microbiol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib58","doi-asserted-by":"crossref","first-page":"3429","DOI":"10.1128\/IAI.66.7.3429-3432.1998","article-title":"Attachment of Cryptosporidium parvum sporozoites to human intestinal epithelial cells","volume":"66","author":"Joe","year":"1998","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib59","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1093\/clinids\/21.Supplement_1.S57","article-title":"Cryptosporidiosis. Sources of infection and guidelines for prevention","volume":"21","author":"Juranek","year":"1995","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib60","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1002\/j.1551-8833.1995.tb06423.x","article-title":"Cryptosporidiosis and public health: workshop report","volume":"87","author":"Juranek","year":"1995","journal-title":"J Am Waterworks Assoc"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib61","doi-asserted-by":"crossref","first-page":"937","DOI":"10.1083\/jcb.147.5.937","article-title":"Conservation of a gliding motility and cell invasion machinery in apicomplexan parasites","volume":"147","author":"Kappe","year":"1999","journal-title":"J Cell Biol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib62","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1385\/MB:12:2:173","article-title":"Generation of recombinant antibodies","volume":"12","author":"Kipriyanov","year":"1999","journal-title":"Mol Biotechnol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib63","doi-asserted-by":"crossref","first-page":"268","DOI":"10.1128\/CDLI.12.2.268-272.2005","article-title":"Evaluation of recombinant oocyst protein CP41 for detection of Cryptosporidium-specific antibodies","volume":"12","author":"Kjos","year":"2005","journal-title":"Clin Diagn Lab Immunol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib64","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1093\/clinids\/18.5.731","article-title":"Seroprevalence of Cryptosporidial antibodies during infancy, childhood, and adolescence","volume":"18","author":"Kuhls","year":"1994","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib65","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/0166-6851(92)90155-D","article-title":"A 2358-base pair DNA fragment from Cryptosporidium parvum encoding a repetitive oocyst protein","volume":"56","author":"Lally","year":"1992","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib66","doi-asserted-by":"crossref","first-page":"5282","DOI":"10.1128\/IAI.67.10.5282-5291.1999","article-title":"Cryptosporidium parvum apical complex glycoprotein CSL contains a sporozoite ligand for intestinal epithelial cells","volume":"67","author":"Langer","year":"1999","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib67","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.1128\/IAI.69.3.1661-1670.2001","article-title":"Characterization of an intestinal epithelial cell receptor recognized by the Cryptosporidium parvum sporozoite ligand CSL","volume":"69","author":"Langer","year":"2001","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib68","doi-asserted-by":"crossref","first-page":"3881","DOI":"10.1128\/IAI.70.7.3881-3890.2002","article-title":"Analysis of sequence diversity at the highly polymorphic Cpgp40\/15 locus among Cryptosporidium isolates from human immunodeficiency virus-infected children in South Africa","volume":"70","author":"Leav","year":"2002","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib69","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1093\/infdis\/167.5.1252","article-title":"Increased exposure to cryptosporidia among dairy farmers in Wisconsin","volume":"167","author":"Lengerich","year":"1993","journal-title":"J Infect Dis"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib70","unstructured":"Levine, N. D., ed. (1985). Phylum II Apicomplexa Levine 1970, pp. 322\u2013374. Allen Press, Lawrence."},{"key":"10.1016\/j.biotechadv.2006.08.003_bib71","first-page":"103","article-title":"Cryptosporidium contamination of water in the USA and UK: a mini review","volume":"44","author":"Lisle","year":"1995","journal-title":"J Water SRT-Auat"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib72","doi-asserted-by":"crossref","first-page":"364","DOI":"10.1016\/S0167-5699(00)01668-6","article-title":"Of mice and men: hybridoma and recombinant antibodies","volume":"21","author":"Little","year":"2000","journal-title":"Immunol Today"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib73","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/S0166-6851(99)00228-5","article-title":"Molecular characterization of a thrombospondin-related anonymous protein homologue in Neospora caninum","volume":"107","author":"Lovett","year":"2000","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib74","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1007\/s00239-002-2412-3","article-title":"Population structures and the role of genetic exchange in the zoonotic pathogen Cryptosporidium parvum","volume":"56","author":"Mallon","year":"2003","journal-title":"J Mol Evol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib75","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1016\/S1567-1348(03)00089-3","article-title":"Multilocus genotyping of Cryptosporidium parvum Type 2: population genetics and sub-structuring","volume":"3","author":"Mallon","year":"2003","journal-title":"Infect Genet Evol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib76","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1016\/j.vetpar.2004.11.033","article-title":"Immunization protocols against Cryptosporidium parvum in ovines: protection in suckling lambs","volume":"129","author":"Martin-Gomez","year":"2005","journal-title":"Vet Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib77","doi-asserted-by":"crossref","first-page":"135","DOI":"10.2307\/3282489","article-title":"Antigens of Cryptosporidium sporozoites recognized by immune serum of infected animals and humans","volume":"74","author":"Mead","year":"1988","journal-title":"J Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib78","doi-asserted-by":"crossref","first-page":"1156","DOI":"10.1016\/S0016-5085(76)80331-9","article-title":"Overwhelming watery diarrhea associated with a Cryptosporidium in an immunosuppressed patient","volume":"70","author":"Meisel","year":"1976","journal-title":"Gastroenterology"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib79","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1006\/expr.1994.1054","article-title":"Attachment of Toxoplasma gondii to host cells involved major surface protein SAG-1 (P30)","volume":"79","author":"Mineo","year":"1994","journal-title":"Exp Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib80","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1016\/S0163-7258(97)82003-7","article-title":"DNA vaccines","volume":"74","author":"Montgomery","year":"1997","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib81","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1128\/IAI.56.3.649-653.1988","article-title":"Lacteal immunity to enteric cyrptosporidiosis in mice: immune dams do not protect their suckling pups","volume":"56","author":"Moon","year":"1988","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib82","doi-asserted-by":"crossref","first-page":"1306","DOI":"10.1128\/IAI.72.3.1306-1310.2004","article-title":"Cryptosporidium parvum-specific CD4 Th1 cells from sensitized donors responding to both fractionated and recombinant antigenic proteins","volume":"72","author":"Morales","year":"2004","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib83","doi-asserted-by":"crossref","first-page":"433","DOI":"10.1111\/j.1550-7408.2002.tb00224.x","article-title":"Cryptosporidium hominis n. sp. (Apicomplexa: Cryptosporidiiae) from Homo sapiens","volume":"49","author":"Morgan-Ryan","year":"2002","journal-title":"J Eukaryot Microbiol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib84","first-page":"66","article-title":"Cytoskeleton of apicomplexan parasites","author":"Morrissette","year":"2002","journal-title":"Microbiol Mol Biol Rev"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib86","first-page":"52S","article-title":"Kinetic and isotypic analysis of specific immunoglobulins from crew members with cryptosporidiosis on a US Coast Guard cutter","volume":"41","author":"Moss","year":"1994","journal-title":"J Eukaryot Microbiol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib85","doi-asserted-by":"crossref","first-page":"827","DOI":"10.1086\/515377","article-title":"The antibody response to 27-, 17-, and 150\u00a0kDa Cryptosporidium antigens following experimental infections in humans","volume":"178","author":"Moss","year":"1998","journal-title":"J Infect Dis"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib87","doi-asserted-by":"crossref","first-page":"2022","DOI":"10.1128\/IAI.67.4.2022-2024.1999","article-title":"Characterization of an immunogenic glycocalyx on the surfaces of Cryptosporidium parvum oocysts and sporozoites","volume":"67","author":"Nanduri","year":"1999","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib88","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0925-4439(99)00034-4","article-title":"Receptor\/ligand interactions between Cryptosporidium parvum and the surface of the host cell","volume":"1454","author":"Nesterenko","year":"1999","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib89","doi-asserted-by":"crossref","first-page":"500","DOI":"10.7326\/0003-4819-120-6-199403150-00009","article-title":"Household epidemiology of Cryptosporidium parvum infection in an urban community in Northeast Brazil","volume":"120","author":"Newman","year":"1994","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib90","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1016\/S0016-5085(76)80503-3","article-title":"Acute enterocolitis in a human being infected with Cryptosporidium","volume":"70","author":"Nime","year":"1976","journal-title":"Gastroenterology"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib91","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1097\/00002030-199006000-00015","article-title":"Treatment with bovine hyperimmune bovine colostrum of cryptosporidial diarrhea in AIDS patients","volume":"4","author":"Nord","year":"1990","journal-title":"AIDS"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib92","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/0020-7519(94)E0059-V","article-title":"Cryptosporidium and cryptosporidiosis in man and animals","volume":"25","author":"O'Donoghue","year":"1995","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib94","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1128\/IAI.66.2.441-443.1998","article-title":"Susceptibility and serologic response of healthy adults to reinfection with Cryptosporidium parvum","volume":"66","author":"Okhuysen","year":"1998","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib93","doi-asserted-by":"crossref","first-page":"1275","DOI":"10.1086\/315033","article-title":"Virulence of three distinct Cryptosporidium parvum isolates for healthy adults","volume":"180","author":"Okhuysen","year":"1999","journal-title":"J Infect Dis"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib95","doi-asserted-by":"crossref","first-page":"567","DOI":"10.3201\/eid0304.970423","article-title":"Genetic polymorphism among Cryptosporidium parvum isolates: evidence of two distinct human transmission cycles","volume":"3","author":"Peng","year":"1997","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib98","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1128\/IAI.58.1.257-259.1990","article-title":"Kinetics of Cryptosporidium parvum sporozoite neturalization by monoclonal antibodies, immune bovine serum, and immune bovine colostrum","volume":"58","author":"Perryman","year":"1990","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib96","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/0166-6851(96)02681-3","article-title":"A cloned gene of Cryptosporidium parvum encodes neutralization-sensitive epitopes","volume":"80","author":"Perryman","year":"1996","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib97","doi-asserted-by":"crossref","first-page":"2142","DOI":"10.1016\/S0264-410X(98)00477-0","article-title":"Protection of calves against cryptosporidiosis with immune bovine colostrums induced by a Cryptosporidium parvum recombinant protein","volume":"17","author":"Perryman","year":"1999","journal-title":"Vaccine"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib99","doi-asserted-by":"crossref","first-page":"5132","DOI":"10.1128\/IAI.60.12.5132-5138.1992","article-title":"Characterization of a >\u00a0900,000-Mr Cryptosporidium parvum sporozoite glycoprotein recognized by protective hyperimune bovine colostral immunoglobulin","volume":"60","author":"Petersen","year":"1992","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib100","doi-asserted-by":"crossref","first-page":"2343","DOI":"10.1128\/IAI.60.6.2343-2348.1992","article-title":"Identification and initial characterization of five Cryptosporidium parvum sporozoite antigen genes","volume":"60","author":"Petersen","year":"1992","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib101","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1645\/0022-3395(2002)088[0641:IOTOCP]2.0.CO;2","article-title":"Influence of temperature on Cryptosporidium parvum oocyst infectivity in river water samples as detected by tissue culture assay","volume":"88","author":"Pokorny","year":"2002","journal-title":"J Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib102","doi-asserted-by":"crossref","first-page":"1504","DOI":"10.1084\/jem.151.6.1504","article-title":"Monovalent fragments (Fab) of monoclonal antibodies to a sporozoite surface antigen (PB44) protect mice against malarial infection","volume":"151","author":"Potocnjak","year":"1980","journal-title":"J Exp Med"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib105","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1128\/JCM.37.5.1385-1392.1999","article-title":"Detection by enzyme immunoassay of serum immunoglobulin G antibodies that recognize specific Cryptosporidium parvum antigens","volume":"37","author":"Priest","year":"1999","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib104","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0166-6851(99)00223-6","article-title":"Cloning of the immunodominant 17-kDa antigen from Cryptosporidium parvum","volume":"106","author":"Priest","year":"2000","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib103","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/S0166-6851(00)00386-8","article-title":"The immunodominant 17-kDa antigen from C. parvum is glycosylphosphatidylinositol-anchored","volume":"113","author":"Priest","year":"2001","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib106","doi-asserted-by":"crossref","first-page":"522212","DOI":"10.1074\/jbc.M306835200","article-title":"Characterization of a low molecular weight glycolipid antigen from Cryptosporidium parvum","volume":"278","author":"Priest","year":"2003","journal-title":"J Biol Chem"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib107","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1111\/j.1574-6968.1992.tb05534.x","article-title":"Immunological characterization of a 17-kDa antigen from Cryptosporidium parvum recognized early by mucosal IgA antibodies","volume":"99","author":"Reperant","year":"1992","journal-title":"FEMS Microbiol Lett"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib108","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/0304-4017(94)90051-5","article-title":"Major antigens of Cryptosporidium parvum regocnized by serum antibodies from different infected animal species and man","volume":"55","author":"Reperant","year":"1994","journal-title":"Vet Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib110","series-title":"Cryptosporidium and Cryptosporidiosis","first-page":"129","article-title":"Immunology: host response and development of passive immunotherapy and vaccines","author":"Riggs","year":"1997"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib111","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1016\/S1286-4579(02)01631-3","article-title":"Recent advances in cryptosporidiosis: the immune response","volume":"4","author":"Riggs","year":"2002","journal-title":"Microbes Infect"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib114","doi-asserted-by":"crossref","first-page":"2081","DOI":"10.1128\/IAI.55.9.2081-2087.1987","article-title":"Infectivity and neutralization of Cryptosporidium parvum sporozoites","volume":"55","author":"Riggs","year":"1987","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib112","doi-asserted-by":"crossref","first-page":"1340","DOI":"10.4049\/jimmunol.143.4.1340","article-title":"Neutralization-sensitive epitopes are exposed on the surface of infectious Cryptosporidium sporozoites","volume":"143","author":"Riggs","year":"1989","journal-title":"J Immunol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib109","doi-asserted-by":"crossref","first-page":"1927","DOI":"10.1128\/IAI.62.5.1927-1939.1994","article-title":"Bovine antibody against Cryptosporidium parvum elicits a circumsporozoite precipitate-like reaction and has immunotherapeutic effect against persistent cryptosporidiosis in SCID mice","volume":"62","author":"Riggs","year":"1994","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib116","doi-asserted-by":"crossref","first-page":"1787","DOI":"10.4049\/jimmunol.158.4.1787","article-title":"Protective monoclonal antibody defines a circumsporozoite-like glycoprotein exoantigen of Cryptosporidium parvum sporozoites and merozoites","volume":"158","author":"Riggs","year":"1997","journal-title":"J Immunol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib113","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1128\/IAI.67.3.1317-1322.1999","article-title":"Cryptosporidium parvum sporozoite pellicle antigen recognized by a neutralizing monoclonal antibody is a B-mannosylated glycolipid","volume":"67","author":"Riggs","year":"1999","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib115","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1128\/AAC.46.2.275-282.2002","article-title":"Efficacy of monoclonal antibodies against defined antigens for passive immunotherapy of chronic gastrointestinal cryptosporidiosis","volume":"46","author":"Riggs","year":"2002","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib117","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1038\/335079a0","article-title":"A highly conserved amino acid sequence in thrombospondin, properdin and in proteins from sporozoites and blood stages of a human malaria parasite","volume":"335","author":"Robson","year":"1988","journal-title":"Nature"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib118","first-page":"709","article-title":"Environmental ecology of Cryptosporidium and public health impacts","volume":"81","author":"Rose","year":"1997","journal-title":"Ann Rev Publ Health"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib120","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.4315\/0362-028X-62.9.1059","article-title":"Giardia, Cryptosporidium, and Cyclospora and their impact on foods: a review","volume":"62","author":"Rose","year":"1999","journal-title":"J Food Prot"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib119","doi-asserted-by":"crossref","first-page":"113","DOI":"10.1111\/j.1574-6976.2002.tb00604.x","article-title":"Risk and control of waterborne cryptosporidiosis","volume":"26","author":"Rose","year":"2002","journal-title":"FEMS Microbiol Rev"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib121","doi-asserted-by":"crossref","first-page":"507","DOI":"10.1046\/j.1365-3024.1999.00247.x","article-title":"Nasal immunization of mice with Cryptosporidium parvum DNA induces systemic and intestinal immune responses","volume":"21","author":"Sagidora","year":"1999","journal-title":"Parasite Immunol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib122","doi-asserted-by":"crossref","first-page":"2346","DOI":"10.1016\/S0264-410X(99)00041-9","article-title":"Protection of kids against Cryptosporidium parvum infection after immunization of dams with CP15-DNA","volume":"17","author":"Sagodira","year":"1999","journal-title":"Vaccine"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib123","doi-asserted-by":"crossref","first-page":"2608","DOI":"10.1128\/IAI.68.5.2608-2616.2000","article-title":"Characterization and formulation of multiple epitope-specific neutralizing monoclonal antibodies for passive immunization against cryptosporidiosis","volume":"68","author":"Schaefer","year":"2000","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib124","doi-asserted-by":"crossref","first-page":"183","DOI":"10.1016\/0166-6851(86)90037-X","article-title":"A rhoptry antigen of Plasmodium falciparum contains conserved and variable epitopes recognized by inhibitory monoclonal antibodies","volume":"18","author":"Schofield","year":"1986","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib125","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1128\/IAI.51.3.760-764.1986","article-title":"Inhibition of penetration-enhancing factor of Toxoplasma gondii by monoclonal antibodies specific for rhoptries","volume":"51","author":"Schwartzman","year":"1986","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib127","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/0169-4758(90)90378-H","article-title":"Waterborne cryptosporidiosis","volume":"6","author":"Smith","year":"1990","journal-title":"Parasitol Today"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib128","doi-asserted-by":"crossref","first-page":"704","DOI":"10.1645\/0022-3395(2001)087[0704:HTABCI]2.0.CO;2","article-title":"Human T and B cell immunoreactivity to a recombinant 23-kDa Cryptosporidium parvum antigen","volume":"87","author":"Smith","year":"2001","journal-title":"J Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib126","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.pt.2005.01.007","article-title":"Cryptosporidium excystation and invasion: getting to the guts of the matter","volume":"21","author":"Smith","year":"2005","journal-title":"Trends Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib130","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1017\/S0031182096008761","article-title":"Cloning of the entire COWP gene of Cryptosporidium parvum and ultrastructural localization of the protein during sexual stage development","volume":"114","author":"Spano","year":"1997","journal-title":"Parasitology"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib129","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1016\/S0166-6851(97)00243-0","article-title":"Molecular cloning and expression analysis of a Cryptosporidium parvum gene encoding a new member of the thrombospondin family","volume":"92","author":"Spano","year":"1998","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib131","doi-asserted-by":"crossref","first-page":"S139","DOI":"10.1097\/00006454-198601001-00022","article-title":"Detection of Cryptosporidium sp. infections using a direct immunofluorescent assay","volume":"5","author":"Sterling","year":"1986","journal-title":"Pediatr Infect Dis"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib132","doi-asserted-by":"crossref","first-page":"1817","DOI":"10.1128\/AEM.68.4.1817-1826.2002","article-title":"Genotyping Cryptosporidium parvum with an hsp70 single-nucleotide polymorphism microarray","volume":"68","author":"Straub","year":"2002","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib133","doi-asserted-by":"crossref","first-page":"4117","DOI":"10.1128\/IAI.68.7.4117-4134.2000","article-title":"Cloning and sequence analysis of a highly polymorphic Cryptosporidium parvum gene encoding a 60-kilodalton glycoprotein and characterization of its 15- and 45-kilodalton zoite surface antigen products","volume":"68","author":"Strong","year":"2000","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib134","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1016\/S0166-6851(03)00017-3","article-title":"Nucleotide changes within three Cryptosporidium parvum surface protein encoding genes differentiate genotype I from genotype II isolates","volume":"128","author":"Sturbaum","year":"2003","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib135","doi-asserted-by":"crossref","first-page":"681","DOI":"10.3201\/eid0404.980424","article-title":"Differentiating human from animal isolates of Cryptosporidium parvum","volume":"4","author":"Sulaiman","year":"1998","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib136","doi-asserted-by":"crossref","first-page":"276","DOI":"10.4269\/ajtmh.1992.47.276","article-title":"Efficacy of bovine milk immunoglobulin concentrate in preventing illness after Shigella flexneri challenge","volume":"47","author":"Tacket","year":"1992","journal-title":"Am J Trop Med Hyg"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib137","doi-asserted-by":"crossref","first-page":"276","DOI":"10.1645\/0022-3395(2003)089[0276:RBHEPP]2.0.CO;2","article-title":"Recombinant bovine herpesvirus-1 expressing p23 protein of Cryptosporidium parvum induces neutralizing antibodies in rabbits","volume":"89","author":"Takashima","year":"2003","journal-title":"J Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib138","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1128\/IAI.72.2.980-987.2004","article-title":"The Cryptosporidium oocyst wall protein is a member of a multigene family and has a homolog in Toxoplasma","volume":"72","author":"Templeton","year":"2004","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib141","doi-asserted-by":"crossref","first-page":"1513","DOI":"10.1139\/z90-224","article-title":"Electrophoretic characterization of Cryptosporidium parvum (KSU-1 isolate) (Apicomplexa: Cryptosporidiidae)","volume":"68","author":"Tilley","year":"1990","journal-title":"Can J Zool"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib142","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1111\/j.1574-6968.1994.tb07045.x","article-title":"Both CP15 and CP25 are left as trails behind gliding sprorozoites of Cryptosporidium parvum (Apicomplexa)","volume":"120","author":"Tilley","year":"1994","journal-title":"FEMS Microbiol Lett"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib140","doi-asserted-by":"crossref","first-page":"2966","DOI":"10.1128\/IAI.58.9.2966-2971.1990","article-title":"Antigens of oocysts and sporozoites of Cryptosporidium parvum (Apicomplexa: Cryptosporidiidae) recognized by bovine colostral antibodies","volume":"58","author":"Tilley","year":"1990","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib143","doi-asserted-by":"crossref","first-page":"1002","DOI":"10.1128\/IAI.59.3.1002-1007.1991","article-title":"Identification of a 15-kilodalton surface glycoprotein on sporozoites of Cryptosporidium parvum","volume":"59","author":"Tilley","year":"1991","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib139","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/j.1574-6968.1993.tb06520.x","article-title":"Multiple oral inoculations with Cryptosporidium parvum as a means of immunization for production of monoclonal antibodies","volume":"13","author":"Tilley","year":"1993","journal-title":"FEMS Microbiol Lett"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib145","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1016\/S1471-4922(00)01761-X","article-title":"Mix and match modules: structure and function of microneme proteins in apicomplexan parasites","volume":"17","author":"Tomley","year":"2001","journal-title":"Trends Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib144","doi-asserted-by":"crossref","first-page":"277","DOI":"10.1016\/0166-6851(91)90071-D","article-title":"Sequence of the gene encoding an immunodominant microneme protein of Eimeria tenella","volume":"49","author":"Tomley","year":"1991","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib147","doi-asserted-by":"crossref","first-page":"1925","DOI":"10.1016\/S0020-7519(99)00158-7","article-title":"Identification and characterization of three antigenic proteins from Cryptosporidium parvum sporozoites using a DNA library expressing poly-histidine tagged peptides","volume":"29","author":"Tosini","year":"1999","journal-title":"Int J Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib146","doi-asserted-by":"crossref","first-page":"137","DOI":"10.1016\/j.molbiopara.2003.11.014","article-title":"A new modular protein of Cryptosporidium parvum, with ricin B and LCCL domains, expressed in the sporozoite invasive stage","volume":"134","author":"Tosini","year":"2004","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib149","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1016\/S0065-308X(08)60116-5","article-title":"Natural history and biology of Cryptosporidium parvum","volume":"40","author":"Tzipori","year":"1998","journal-title":"Adv Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib148","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/S1286-4579(02)01629-5","article-title":"Cryptosporidiosis: biology, pathogenesis and disease","volume":"4","author":"Tzipori","year":"2002","journal-title":"Microbes Infect"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib152","first-page":"1","article-title":"The biology of Cryptosporidium","volume":"vol. 6","author":"Tzipori","year":"2000"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib150","doi-asserted-by":"crossref","first-page":"1276","DOI":"10.1136\/bmj.293.6557.1276","article-title":"Remission of diarrhea due to cryptosporidiosis in an immunodeficient child treated with hyperimmune bovine colostrum","volume":"2933","author":"Tzipori","year":"1986","journal-title":"Br Med J"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib151","doi-asserted-by":"crossref","first-page":"344","DOI":"10.1016\/S0140-6736(87)90944-5","article-title":"Chronic cryptosporidial diarrhoae and hyperimmune cow colostrum","author":"Tzipori","year":"1987","journal-title":"Lancet"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib155","doi-asserted-by":"crossref","first-page":"124","DOI":"10.1128\/IAI.53.1.124-128.1986","article-title":"Quantification of specific antibody response to Cryptosporidium antigens by laser densitometry","volume":"53","author":"Ungar","year":"1986","journal-title":"Infect Immun"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib153","doi-asserted-by":"crossref","first-page":"551","DOI":"10.1093\/infdis\/157.3.551","article-title":"Seroepidemiology of Cryptosporidium infection in two Latin American populations","volume":"157","author":"Ungar","year":"1988","journal-title":"J Infect Dis"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib154","doi-asserted-by":"crossref","first-page":"894","DOI":"10.1001\/archinte.1989.00390040100020","article-title":"Serologic evidence of Cryptosporidium infection in U.S. volunteers before and during Peace Corps service in Africa","volume":"149","author":"Ungar","year":"1989","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib156","doi-asserted-by":"crossref","first-page":"486","DOI":"10.1016\/0016-5085(90)90842-O","article-title":"Cessation of Cryptosporidium-associated diarrhea in an AIDS patient after treatment with hyperimmune bovine colostrum","volume":"98","author":"Unger","year":"1990","journal-title":"Gastroenterology"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib157","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1016\/S0166-6851(96)02796-X","article-title":"Molecular characterisation of an expressed sequence tag locus of Toxoplasma gondii encoding the micronemal protein MIC2","volume":"84","author":"Wan","year":"1997","journal-title":"Mol Biochem Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib158","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S0065-308X(08)60120-7","article-title":"Cryptosporidium: molecular basis of host-parasite interaction","volume":"40","author":"Ward","year":"1998","journal-title":"Adv Parasitol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib159","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1038\/sj.jim.2900566","article-title":"PCR detection of Cryptosporidium parvum in environmental samples\u2014a review of published protocols and current developments","volume":"21","author":"Weidenmann","year":"1998","journal-title":"J Ind Microbiol Methods"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib160","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1128\/CDLI.7.5.745-750.2000","article-title":"An immunoglobulin G1 monoclonal antibody highly specific to the wall of Cryptosporidium oocysts","volume":"7","author":"Weir","year":"2000","journal-title":"Clin Diagn Lab Immunol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib161","doi-asserted-by":"crossref","first-page":"207","DOI":"10.1007\/s101420000028","article-title":"Characterization of a major sporozoite surface glycoprotein of Cryptosporidium parvum","volume":"1","author":"Winter","year":"2000","journal-title":"Funct Integr Genomics"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib162","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1574-6968.1998.tb13255.x","article-title":"Efficacy of select antivirals against Cryptosporidium parvum in vitro","volume":"168","author":"Woods","year":"1998","journal-title":"FEMS Microbiol Lett"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib163","doi-asserted-by":"crossref","first-page":"4720","DOI":"10.1128\/AEM.69.8.4720-4726.2003","article-title":"Intraspecies polymorphism of Cryptosporidium parvum revealed by PCR-restriction fragment length polymorphism (RFLP) and RFLP-single-strand conformational polymorphism analyses","volume":"69","author":"Wu","year":"2003","journal-title":"Appl Environ Microbiol"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib165","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/S0169-4758(00)01699-9","article-title":"Cryptosporidium systematics and implications for public health","volume":"16","author":"Xiao","year":"2000","journal-title":"Parisitol Today"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib164","doi-asserted-by":"crossref","first-page":"72","DOI":"10.1128\/CMR.17.1.72-97.2004","article-title":"Cryptosporidium taxonomy: recent advances and implications for public health","volume":"17","author":"Xiao","year":"2004","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.biotechadv.2006.08.003_bib166","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1016\/S0734-9750(03)00104-6","article-title":"Emerging trends in the synthesis and improvement of hapten-specific recombinant antibodies","volume":"21","author":"Yau","year":"2003","journal-title":"Biotechnol Adv"}],"container-title":["Biotechnology Advances"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073497500600098X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S073497500600098X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,5,8]],"date-time":"2023-05-08T18:50:22Z","timestamp":1683571822000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S073497500600098X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,1]]},"references-count":166,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2007,1]]}},"alternative-id":["S073497500600098X"],"URL":"https:\/\/doi.org\/10.1016\/j.biotechadv.2006.08.003","relation":{},"ISSN":["0734-9750"],"issn-type":[{"value":"0734-9750","type":"print"}],"subject":[],"published":{"date-parts":[[2007,1]]}}}