{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:45:10Z","timestamp":1791308710117,"version":"4.3.1"},"reference-count":160,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2015,11,1]],"date-time":"2015-11-01T00:00:00Z","timestamp":1446336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2015,11,1]],"date-time":"2015-11-01T00:00:00Z","timestamp":1446336000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100001823","name":"Ministerstvo \u0160kolstv\u00ed, Ml\u00e1de\u017ee a T\u011blov\u00fdchovy","doi-asserted-by":"publisher","award":["CZ.1.05\/3.1.00\/14.0302"],"award-info":[{"award-number":["CZ.1.05\/3.1.00\/14.0302"]}],"id":[{"id":"10.13039\/501100001823","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001823","name":"Ministerstvo \u0160kolstv\u00ed, Ml\u00e1de\u017ee a T\u011blov\u00fdchovy","doi-asserted-by":"publisher","award":["CZ.1.07\/2.3.00\/20.0155"],"award-info":[{"award-number":["CZ.1.07\/2.3.00\/20.0155"]}],"id":[{"id":"10.13039\/501100001823","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001823","name":"Ministerstvo \u0160kolstv\u00ed, Ml\u00e1de\u017ee a T\u011blov\u00fdchovy","doi-asserted-by":"publisher","award":["IGA_PrF_2014023"],"award-info":[{"award-number":["IGA_PrF_2014023"]}],"id":[{"id":"10.13039\/501100001823","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004895","name":"European Social Fund","doi-asserted-by":"publisher","award":["CZ.1.07\/2.3.00\/20.0155"],"award-info":[{"award-number":["CZ.1.07\/2.3.00\/20.0155"]}],"id":[{"id":"10.13039\/501100004895","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004895","name":"European Social Fund","doi-asserted-by":"publisher","award":["CZ.1.05\/3.1.00\/14.0302"],"award-info":[{"award-number":["CZ.1.05\/3.1.00\/14.0302"]}],"id":[{"id":"10.13039\/501100004895","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biotechnology Advances"],"published-print":{"date-parts":[[2015,11]]},"DOI":"10.1016\/j.biotechadv.2015.02.003","type":"journal-article","created":{"date-parts":[[2015,2,14]],"date-time":"2015-02-14T09:33:31Z","timestamp":1423906411000},"page":"1162-1176","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":350,"special_numbering":"P2","title":["Tailored functionalization of iron oxide nanoparticles for MRI, drug delivery, magnetic separation and immobilization of biosubstances"],"prefix":"10.1016","volume":"33","author":[{"given":"Katerina","family":"Hola","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zdenka","family":"Markova","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2304-2564","authenticated-orcid":false,"given":"Giorgio","family":"Zoppellaro","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiri","family":"Tucek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Radek","family":"Zboril","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biotechadv.2015.02.003_bb0005","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1016\/S0168-1656(97)00179-X","article-title":"Stability of alpha-amylase immobilized on poly(methyl methacrylate-acrylic acid) microspheres","volume":"60","author":"Aksoy","year":"1998","journal-title":"J Biotechnol"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0010","doi-asserted-by":"crossref","first-page":"38","DOI":"10.1016\/j.jhazmat.2010.04.105","article-title":"Water purification using magnetic assistance: a review","volume":"180","author":"Ambashta","year":"2010","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0015","doi-asserted-by":"crossref","first-page":"512","DOI":"10.1016\/j.biotechadv.2011.09.005","article-title":"Potential applications of enzymes immobilized on\/in nano materials: a review","volume":"30","author":"Ansari","year":"2012","journal-title":"Biotechnol Adv"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0020","doi-asserted-by":"crossref","first-page":"188","DOI":"10.1016\/j.jcis.2013.11.023","article-title":"Ethylene diamine-assisted synthesis of iron oxide nanoparticles in high-boiling polyolys","volume":"417","author":"Arndt","year":"2014","journal-title":"J Colloid Interface Sci"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0025","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1073\/pnas.97.2.745","article-title":"Enzymatic reduction of disulfide bonds in lysosomes: characterization of a gamma-interferon-inducible lysosomal thiol reductase (GILT)","volume":"97","author":"Arunachalam","year":"2000","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0030","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1021\/bc700410z","article-title":"Poly(L-lysine)-modified iron oxide nanoparticles for stem cell labeling","volume":"19","author":"Babic","year":"2008","journal-title":"Bioconjug Chem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0035","doi-asserted-by":"crossref","first-page":"2155","DOI":"10.1021\/sc500341h","article-title":"Magnetic carbon-supported palladium nanoparticles: an efficient and sustainable catalyst for hydrogenation reactions","volume":"2","author":"Baig","year":"2014","journal-title":"ACS Sustainable Chem Eng"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0040","doi-asserted-by":"crossref","first-page":"564","DOI":"10.1039\/b9nr00253g","article-title":"Preparation, stability and cytocompatibility of magnetic\/PLA-PEG hybrids","volume":"2","author":"Bakandritsos","year":"2010","journal-title":"Nanoscale"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0045","doi-asserted-by":"crossref","first-page":"2381","DOI":"10.1002\/smll.201102525","article-title":"Merging high doxorubicin loading with pronounced magnetic response and bio-repellent properties in hybrid drug nanocarriers","volume":"8","author":"Bakandritsos","year":"2012","journal-title":"Small"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0050","doi-asserted-by":"crossref","first-page":"505104","DOI":"10.1088\/0957-4484\/19\/50\/505104","article-title":"Multifunctional pH-sensitive magnetic nanoparticles for simultaneous imaging, sensing and targeted intracellular anticancer drug delivery","volume":"19","author":"Banerjee","year":"2008","journal-title":"Nanotechnology"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0055","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1016\/S0378-5173(02)00267-3","article-title":"Preparation, characterization and biodistribution of ultrafine chitosan nanoparticles","volume":"243","author":"Banerjee","year":"2002","journal-title":"Int J Pharm"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0060","doi-asserted-by":"crossref","first-page":"10782","DOI":"10.1021\/la901337r","article-title":"Synthesis of magnetic Fe2O3\/Au core\/shell nanoparticles for bioseparation and immunoassay based on surface-enhanced Raman spectroscopy","volume":"25","author":"Bao","year":"2009","journal-title":"Langmuir"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0065","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1002\/nbm.3117","article-title":"Alginate-coated magnetic nanoparticles for noninvasive MRI of extracellular calcium","volume":"27","author":"Bar-Shir","year":"2014","journal-title":"NMR Biomed"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0070","doi-asserted-by":"crossref","first-page":"744","DOI":"10.1039\/C3CS60273G","article-title":"Chemical modifications and bioconjugate reactions of nanomaterials for sensing, imaging, drug delivery and therapy","volume":"43","author":"Biju","year":"2014","journal-title":"Chem Soc Rev"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0075","doi-asserted-by":"crossref","first-page":"377","DOI":"10.1126\/science.170679","article-title":"Magnetotactic bacteria","volume":"190","author":"Blakemore","year":"1975","journal-title":"Science"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0080","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/S0021-9673(01)95956-4","article-title":"Bead cellulose derivatives as supports for immobilization and chromatographic purification of proteins","volume":"552","author":"Boeden","year":"1991","journal-title":"J Chromatogr"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0085","doi-asserted-by":"crossref","first-page":"7821","DOI":"10.1016\/j.chroma.2011.08.084","article-title":"Potential of boronic acid functionalized magnetic particles in the adsorption of human antibodies under mammalian cell culture conditions","volume":"1218","author":"Borlido","year":"2011","journal-title":"J Chromatogr A"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0090","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1016\/j.biotechadv.2013.05.009","article-title":"Magnetic separations in biotechnology","volume":"31","author":"Borlido","year":"2013","journal-title":"Biotechnol Adv"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0095","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1016\/j.nantod.2013.06.001","article-title":"Nanoparticles for cancer imaging: the good, the bad, and the promise","volume":"8","author":"Chapman","year":"2013","journal-title":"Nano Today"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0105","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1016\/j.biomaterials.2007.08.050","article-title":"Iron oxide nanoparticles as a drug delivery vehicle for MRI monitored magnetic targeting of brain tumors","volume":"29","author":"Chertok","year":"2008","journal-title":"Biomaterials"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0110","doi-asserted-by":"crossref","first-page":"2685","DOI":"10.1021\/cg8013199","article-title":"Facile and green approach to fabricate gold and silver coated superparamagnetic nanoparticles","volume":"9","author":"Chin","year":"2009","journal-title":"Cryst Growth Des"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0115","doi-asserted-by":"crossref","first-page":"1165","DOI":"10.1038\/nbt1340","article-title":"Renal clearance of quantum dots","volume":"25","author":"Choi","year":"2007","journal-title":"Nat Biotechnol"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0120","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/j.vibspec.2010.01.001","article-title":"Surface-enhanced Raman scattering inducible by recyclable Ag-coated magnetic particles","volume":"53","author":"Choi","year":"2010","journal-title":"Vib Spectrosc"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0125","doi-asserted-by":"crossref","first-page":"1233","DOI":"10.1016\/j.jmmm.2010.11.012","article-title":"Antifungal activity of multifunctional Fe3O4\u2013Ag nanocolloids","volume":"323","author":"Chudasama","year":"2011","journal-title":"J Magn Magn Mater"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0130","doi-asserted-by":"crossref","first-page":"4329","DOI":"10.1021\/nn201198f","article-title":"Facile synthetic route for surface-functionalized magnetic magnetic resonance imaging studies","volume":"5","author":"Chung","year":"2011","journal-title":"ACS Nano"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0135","doi-asserted-by":"crossref","first-page":"6291","DOI":"10.1016\/j.biomaterials.2011.05.024","article-title":"Magnetic brain tumor targeting and biodistribution of long-circulating PEG-modified, cross-linked starch-coated iron oxide nanoparticles","volume":"32","author":"Cole","year":"2011","journal-title":"Biomaterials"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0140","series-title":"The Iron Oxides: Structure, Properties, Reactions, Occurrence and Uses","author":"Cornell","year":"2003"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0145","doi-asserted-by":"crossref","first-page":"1735","DOI":"10.1021\/cs500337a","article-title":"Organometallic preparation of Ni, Pd, and NiPd nanoparticles for the design of supported nanocatalysts","volume":"4","author":"Costa","year":"2014","journal-title":"ACS Catal"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0150","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.jmmm.2013.11.006","article-title":"Heating efficiency in magnetic nanoparticle hyperthermia","volume":"354","author":"Deatsch","year":"2014","journal-title":"J Magn Magn Mater"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0155","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1039\/C0NR00570C","article-title":"Magnetic nanobeads decorated by thermo-responsive PNIPAM shell as medical platforms for the efficient delivery of doxorubicin to tumour cells","volume":"3","author":"Deka","year":"2011","journal-title":"Nanoscale"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0160","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1038\/nnano.2007.223","article-title":"Immunological properties of engineered nanomaterials","volume":"2","author":"Dobrovolskaia","year":"2007","journal-title":"Nat Nanotechnol"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0165","doi-asserted-by":"crossref","first-page":"8127","DOI":"10.1021\/jp8029083","article-title":"Reexamining the effects of particle size and surface chemistry on the magnetic properties of iron oxide nanocrystals: new insights into spin disorder and proton relaxivity","volume":"112","author":"Duan","year":"2008","journal-title":"J Phys Chem C"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0170","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1039\/c2cs15327k","article-title":"Design of polymeric nanoparticles for biomedical delivery applications","volume":"41","author":"Elsabahy","year":"2012","journal-title":"Chem Soc Rev"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0175","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1002\/smll.200801647","article-title":"Functionalized nanoparticles with long-term stability in biological media","volume":"5","author":"Fang","year":"2009","journal-title":"Small"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0180","doi-asserted-by":"crossref","first-page":"1357","DOI":"10.2217\/nnm.10.55","article-title":"Functionalization of iron oxide magnetic nanoparticles with targeting ligands: their physicochemical properties and in vivo behavior","volume":"5","author":"Fang","year":"2010","journal-title":"Nanomedicine"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0185","doi-asserted-by":"crossref","first-page":"8624","DOI":"10.1039\/c0jm02081h","article-title":"Superparamagnetic core-shell polymer particles for efficient purification of his-tagged proteins","volume":"20","author":"Fang","year":"2010","journal-title":"J Mater Chem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0190","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1007\/s00253-006-0344-3","article-title":"Protein purification using magnetic adsorbent particles","volume":"70","author":"Franzreb","year":"2006","journal-title":"Appl Microbiol Biotechnol"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0195","doi-asserted-by":"crossref","first-page":"432002","DOI":"10.1088\/0957-4484\/24\/43\/432002","article-title":"Design strategies of hybrid metallic nanoparticles for theragnostic applications","volume":"24","author":"Gautier","year":"2013","journal-title":"Nanotechnology"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0200","doi-asserted-by":"crossref","first-page":"3371","DOI":"10.1039\/c3cs35480f","article-title":"Nano-magnetite (Fe3O4) as a support for recyclable catalysts in the development of sustainable methodologies","volume":"42","author":"Gawande","year":"2013","journal-title":"Chem Soc Rev"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0205","doi-asserted-by":"crossref","first-page":"4137","DOI":"10.1039\/C4GC00774C","article-title":"Magnetic gold nanocatalyst (nanocat-Fe\u2013Au): catalytic applications for the oxidative esterification and hydrogen transfer reactions","volume":"16","author":"Gawande","year":"2014","journal-title":"Green Chem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0210","doi-asserted-by":"crossref","first-page":"339","DOI":"10.1006\/cyto.1999.0568","article-title":"Effects of hyperthermia and tumour necrosis factor on inflammatory cytokine secretion and procoagulant activity in endothelial cells","volume":"12","author":"Gnant","year":"2000","journal-title":"Cytokine"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0215","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1016\/j.jmmm.2006.10.1151","article-title":"Synthesis and antibody conjugation of magnetic nanoparticles with improved specific power absorption rates for alternating magnetic field cancer therapy","volume":"311","author":"Gr\u00fcttner","year":"2007","journal-title":"J Magn Magn Mater"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0220","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1021\/ja045220h","article-title":"Heterodimers of nanoparticles: formation at a liquid\u2013liquid interface and particle-specific surface modification by functional molecules","volume":"127","author":"Gu","year":"2005","journal-title":"J Am Chem Soc"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0225","doi-asserted-by":"crossref","first-page":"385","DOI":"10.1002\/pat.1021","article-title":"Synthesis and characterization of fluorescent starch using fluorescein as fluorophore: potential polymeric temperature\/pH indicators","volume":"19","author":"Guan","year":"2008","journal-title":"Polym Adv Technol"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0230","doi-asserted-by":"crossref","first-page":"3080","DOI":"10.1021\/nn2048137","article-title":"Water-soluble iron oxide nanocubes with high values of specific absorption rate for cancer cell hyperthermia treatment","volume":"6","author":"Guardia","year":"2012","journal-title":"ACS Nano"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0235","doi-asserted-by":"crossref","first-page":"1565","DOI":"10.1016\/j.biomaterials.2004.05.022","article-title":"Cytotoxicity suppression and cellular uptake enhancement of surface modified magnetic nanoparticles","volume":"26","author":"Gupta","year":"2005","journal-title":"Biomaterials"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0240","doi-asserted-by":"crossref","first-page":"3995","DOI":"10.1016\/j.biomaterials.2004.10.012","article-title":"Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications","volume":"26","author":"Gupta","year":"2005","journal-title":"Biomaterials"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0245","doi-asserted-by":"crossref","first-page":"3212","DOI":"10.1021\/nn305892j","article-title":"Magnetic silver hybrid nanoparticles for surface-enhanced resonance Raman spectroscopic detection and decontamination of small toxic molecules","volume":"7","author":"Han","year":"2013","journal-title":"ACS Nano"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0250","doi-asserted-by":"crossref","first-page":"2921","DOI":"10.1016\/j.bmc.2007.12.051","article-title":"Synthesis of chemically functionalized superparamagnetic nanoparticles as delivery vectors for chemotherapeutic drugs","volume":"16","author":"Hanessian","year":"2008","journal-title":"Bioorg Med Chem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0255","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1002\/bit.20116","article-title":"Superparamagnetic adsorbents for high-gradient magnetic fishing of lectins out of legume extracts","volume":"87","author":"Heeb\u00f8ll-Nielsen","year":"2004","journal-title":"Biotechnol Bioeng"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0260","doi-asserted-by":"crossref","first-page":"3254","DOI":"10.1021\/es802726v","article-title":"Highly active Pd-on-magnetite nanocatalysts for aqueous phase hydrodechlorination reactions","volume":"43","author":"Hildebrand","year":"2009","journal-title":"Environ Sci Technol"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0270","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0304-8853(03)00566-3","article-title":"Periodate oxidation of nanoscaled magnetic dextran composites","volume":"269","author":"Hong","year":"2004","journal-title":"J Magn Magn Mater"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0265","doi-asserted-by":"crossref","first-page":"290","DOI":"10.1016\/j.bej.2008.07.009","article-title":"Synthesis, characterization and MRI application of dextran-coated Fe3O4 magnetic nanoparticles","volume":"42","author":"Hong","year":"2008","journal-title":"Biochem Eng J"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0285","doi-asserted-by":"crossref","first-page":"4528","DOI":"10.1016\/j.watres.2005.05.051","article-title":"Removal and recovery of Cr(VI) from wastewater by maghemite nanoparticles","volume":"39","author":"Hu","year":"2005","journal-title":"Water Res"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0275","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1039\/B916562B","article-title":"Highly dispersible, superparamagnetic magnetite nanoflowers for magnetic resonance imaging","volume":"46","author":"Hu","year":"2010","journal-title":"Chem Commun"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0290","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1016\/j.jhazmat.2011.10.016","article-title":"Heavy metal removal from water\/wastewater by nanosized metal oxides: a review","volume":"211\u2013212","author":"Hua","year":"2012","journal-title":"J Hazard Mater"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0295","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1016\/j.jnoncrysol.2006.12.050","article-title":"Synthesis of silver-coated magnetite nanoparticles","volume":"353","author":"Iglesias-Silva","year":"2007","journal-title":"J Non Cryst Solids"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0305","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1021\/mp7001285","article-title":"Biodistribution, clearance, and biocompatibility of iron oxide magnetic nanoparticles in rats","volume":"5","author":"Jain","year":"2008","journal-title":"Mol Pharm"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0300","doi-asserted-by":"crossref","first-page":"6748","DOI":"10.1016\/j.biomaterials.2009.08.042","article-title":"Magnetic resonance imaging of multifunctional pluronic stabilized iron-oxide nanoparticles in tumor-bearing mice","volume":"30","author":"Jain","year":"2009","journal-title":"Biomaterials"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0310","doi-asserted-by":"crossref","first-page":"370","DOI":"10.1039\/C3BM60225G","article-title":"Biocompatibility, biodistribution and efficacy of magnetic nanohydrogels in inhibiting growth of tumors in experimental mice models","volume":"2","author":"Jaiswal","year":"2014","journal-title":"Biomater Sci"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0315","doi-asserted-by":"crossref","first-page":"654","DOI":"10.1039\/B919893H","article-title":"A magnetic microchip for controlled transport of attomole levels of proteins","volume":"10","author":"Johansson","year":"2010","journal-title":"Lab Chip"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0320","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1016\/j.molcatb.2010.09.010","article-title":"Preparation and characterization of cellulase-bound magnetite nanoparticles","volume":"68","author":"Jordan","year":"2011","journal-title":"J Mol Catal B: Enzym"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0325","doi-asserted-by":"crossref","first-page":"669","DOI":"10.1016\/j.cej.2011.04.039","article-title":"Immobilization of cellulase enzyme on superparamagnetic nanoparticles and determination of its activity and stability","volume":"171","author":"Khoshnevisan","year":"2011","journal-title":"Chem Eng J"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0330","doi-asserted-by":"crossref","first-page":"2690","DOI":"10.1016\/j.chemosphere.2013.08.071","article-title":"Remarkable efficiency of ultrafine superparamagnetic iron(III) oxide nanoparticles toward arsenate removal from aqueous environment","volume":"93","author":"Kilianova","year":"2013","journal-title":"Chemosphere"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0335","doi-asserted-by":"crossref","first-page":"478","DOI":"10.1002\/adma.200701726","article-title":"Designed fabrication of a multifunctional polymer nanomedical platform for simultaneous cancer-targeted imaging and magnetically guided drug delivery","volume":"20","author":"Kim","year":"2008","journal-title":"Adv Mater"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0340","doi-asserted-by":"crossref","first-page":"2855","DOI":"10.1016\/j.biomaterials.2009.02.023","article-title":"Superparamagnetic maghemite nanoparticles from solid-state synthesis \u2014 their functionalization towards peroral MRI contrast agent and magnetic carrier for trypsin immobilization","volume":"30","author":"Kluchova","year":"2009","journal-title":"Biomaterials"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0345","series-title":"Design of Polymer\u2013Drug Conjugates","first-page":"483","article-title":"Drug delivery in oncology, from basic research to cancer therapy, 17","author":"Kopecek","year":"2011"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0350","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1016\/j.chroma.2004.12.014","article-title":"Magnetic hydrophilic methacrylate-based polymer microspheres for genomic DNA isolation","volume":"1064","author":"Krizova","year":"2005","journal-title":"J Chromatogr A"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0355","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1016\/j.addr.2011.03.008","article-title":"Magnetic nanomaterials for hyperthermia-based therapy and controlled drug delivery","volume":"63","author":"Kumar","year":"2011","journal-title":"Adv Drug Deliv Rev"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0360","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1002\/jmri.21194","article-title":"Coating thickness of magnetic iron oxide nanoparticles affects R2 relaxivity","volume":"26","author":"LaConte","year":"2007","journal-title":"J Magn Reson Imaging"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0370","doi-asserted-by":"crossref","first-page":"10935","DOI":"10.1021\/nn304477s","article-title":"Cooperative organization in iron oxide multi-core nanoparticles potentiates their efficiency as heating mediators and MRI contrast agents","volume":"6","author":"Lartigue","year":"2012","journal-title":"ACS Nano"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0365","doi-asserted-by":"crossref","first-page":"3939","DOI":"10.1021\/nn305719y","article-title":"Biodegradation of iron oxide nanocubes: high-resolution in situ monitoring","volume":"7","author":"Lartigue","year":"2013","journal-title":"ACS Nano"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0375","doi-asserted-by":"crossref","first-page":"2064","DOI":"10.1021\/cr068445e","article-title":"Magnetic iron oxide nanoparticles: synthesis, stabilization, vectorization, physicochemical characterizations, and biological applications","volume":"108","author":"Laurent","year":"2008","journal-title":"Chem Rev"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0395","doi-asserted-by":"crossref","first-page":"2058","DOI":"10.1002\/app.12365","article-title":"Preparation of magnetic ion-exchange resins by the suspension polymerization of styrene with magnetite","volume":"89","author":"Lee","year":"2003","journal-title":"J Appl Polym Sci"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0380","doi-asserted-by":"crossref","first-page":"102","DOI":"10.1016\/j.jmmm.2005.01.049","article-title":"Synthesis of SPIO-chitosan microspheres for MRI-detectable embolotherapy","volume":"293","author":"Lee","year":"2005","journal-title":"J Magn Magn Mater"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0385","doi-asserted-by":"crossref","first-page":"e9536","DOI":"10.1371\/journal.pone.0009536","article-title":"Rapid pharmacokinetic and biodistribution studies using cholorotoxin-conjugated iron oxide nanoparticles: a novel non-radioactive method","volume":"5","author":"Lee","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0390","doi-asserted-by":"crossref","first-page":"2662","DOI":"10.1073\/pnas.1016409108","article-title":"Magnetosome-like ferrimagnetic iron oxide nanocubes for highly sensitive MRI of single cells and transplanted pancreatic islets","volume":"108","author":"Lee","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0400","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1002\/smll.200700595","article-title":"Cytotoxicity of nanoparticles","volume":"4","author":"Lewinski","year":"2008","journal-title":"Small"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0405","doi-asserted-by":"crossref","first-page":"1767","DOI":"10.1002\/adfm.201000188","article-title":"functionalization strategies for protease immobilization on magnetic nanoparticles","volume":"20","author":"Li","year":"2010","journal-title":"Adv Funct Mater"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0410","doi-asserted-by":"crossref","first-page":"600","DOI":"10.1039\/C3CE41618F","article-title":"Controlled synthesis of MnxFe1\u2212xO concave nanocubes and highly branched cubic mesocrystals","volume":"16","author":"Li","year":"2014","journal-title":"CrystEngComm"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0415","doi-asserted-by":"crossref","first-page":"2436","DOI":"10.1002\/adma.201100351","article-title":"pH-triggered drug-releasing magnetic nanoparticles for cancer therapy guided by molecular imaging by MRI","volume":"23","author":"Lim","year":"2011","journal-title":"Adv Mater"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0420","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1021\/pr700586j","article-title":"Novel microwave-assisted digestion by trypsin-immobilized magnetic nanoparticles for proteomic analysis technical notes","volume":"7","author":"Lin","year":"2008","journal-title":"J Proteome Res"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0435","doi-asserted-by":"crossref","first-page":"6652","DOI":"10.1158\/0008-5472.CAN-08-1468","article-title":"Drug delivery with carbon nanotubes for in vivo cancer treatment","volume":"68","author":"Liu","year":"2008","journal-title":"Cancer Res"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0430","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1021\/la802754t","article-title":"Magnetic chitosan nanocomposites: a useful recyclable tool for heavy metal ion removal","volume":"2","author":"Liu","year":"2009","journal-title":"Langmuir"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0440","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1016\/j.talanta.2010.03.019","article-title":"Novel nonenzymatic hydrogen peroxide sensor based on iron oxide-silver hybrid submicrospheres","volume":"81","author":"Liu","year":"2010","journal-title":"Talanta"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0425","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/j.mattod.2013.11.003","article-title":"Renal clearable inorganic nanoparticles: a new frontier of bionanotechnology","volume":"16","author":"Liu","year":"2013","journal-title":"Mater Today"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0445","first-page":"703","volume":"3","author":"Longmire","year":"2012"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0450","doi-asserted-by":"crossref","first-page":"10148","DOI":"10.1021\/jp102311u","article-title":"Ag\u2013Fe3O4 dimer colloidal nanoparticles: synthesis and enhancement of magnetic properties","volume":"114","author":"Lopes","year":"2010","journal-title":"J Phys Chem C"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0455","doi-asserted-by":"crossref","first-page":"3538","DOI":"10.1039\/b900103d","article-title":"In situ synthesis of Fe3O4\/cellulose microspheres with magnetic-induced protein delivery","volume":"19","author":"Luo","year":"2009","journal-title":"J Mater Chem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0475","doi-asserted-by":"crossref","first-page":"4003","DOI":"10.1021\/jp064992s","article-title":"Amourphous iron(III) oxide \u2014 a review","volume":"111","author":"Machala","year":"2007","journal-title":"J Phys Chem B"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0470","doi-asserted-by":"crossref","first-page":"3255","DOI":"10.1021\/cm200397g","article-title":"Polymorphous transformations of nanometric iron(III) oxide: a review","volume":"23","author":"Machala","year":"2011","journal-title":"Chem Mater"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0460","doi-asserted-by":"crossref","first-page":"11913","DOI":"10.1002\/chem.201402820","article-title":"A magnetically drivable nanovehicle for curcumin with antioxidant capacity and MRI relaxation properties","volume":"20","author":"Magro","year":"2014","journal-title":"Chem Eur J"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0465","doi-asserted-by":"crossref","first-page":"14470","DOI":"10.1021\/jp803016n","article-title":"Optimal design and characterization of superparamagnetic iron oxide nanoparticles coated with polyvinyl alcohol for targeted delivery and imaging","volume":"112","author":"Mahmoudi","year":"2008","journal-title":"J Phys Chem B"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0480","doi-asserted-by":"crossref","first-page":"11398","DOI":"10.1039\/c2cc35515a","article-title":"Surface design of core-shell superparamagnetic iron oxide nanoparticles drives record relaxivity values in functional MRI contrast agents","volume":"48","author":"Maity","year":"2012","journal-title":"Chem Commun"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0485","doi-asserted-by":"crossref","first-page":"187","DOI":"10.1016\/j.jcis.2005.01.013","article-title":"Magnetite nanoparticles with tunable gold or silver shell","volume":"286","author":"Mandal","year":"2005","journal-title":"J Colloid Interface Sci"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0490","doi-asserted-by":"crossref","first-page":"16219","DOI":"10.1039\/c2jm33414c","article-title":"Synthesis and properties of core\u2013shell fluorescent hybrids with distinct morphologies based on carbon dots","volume":"22","author":"Markova","year":"2012","journal-title":"J Mater Chem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0495","doi-asserted-by":"crossref","first-page":"2550","DOI":"10.1039\/c2gc35545k","article-title":"Chitosan-based synthesis of magnetically-driven nanocomposites with biogenic magnetite core, controlled silver size, and high antimicrobial activity","volume":"14","author":"Markova","year":"2012","journal-title":"Green Chem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0500","doi-asserted-by":"crossref","first-page":"1247","DOI":"10.1109\/TMAG.1981.1061188","article-title":"Preparation of aqueous magnetic liquids in alkaline and acidic media","volume":"17","author":"Massart","year":"1981","journal-title":"IEEE Trans Magn"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0505","doi-asserted-by":"crossref","first-page":"8857","DOI":"10.1021\/la901602w","article-title":"Easy route to functionalize iron oxide nanoparticles via long-term stable thiol groups","volume":"25","author":"Maurizi","year":"2009","journal-title":"Langmuir"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0510","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1016\/j.addr.2008.03.014","article-title":"Multifunctional magnetic nanoparticles for targeted imaging and therapy","volume":"60","author":"McCarthy","year":"2008","journal-title":"Adv Drug Deliv Rev"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0515","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/0021-9673(95)00114-3","article-title":"Novel magnetic microspheres on the basis of poly(vinyl alcohol) as affinity medium for quantitative detection of glycated haemoglobin","volume":"711","author":"M\u00fcller-Schulte","year":"1995","journal-title":"J Chromatogr A"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0520","doi-asserted-by":"crossref","first-page":"2197","DOI":"10.1002\/adma.200602739","article-title":"Click chemistry: versatility and control in the hands of materials scientists","volume":"19","author":"Nandivada","year":"2007","journal-title":"Adv Mater"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0525","doi-asserted-by":"crossref","first-page":"1191","DOI":"10.1016\/j.matlet.2011.01.042","article-title":"Silver-modified iron oxide nanoparticle impregnated fiberglass for disinfection of bacteria and viruses in water","volume":"65","author":"Nangmenyi","year":"2011","journal-title":"Mater Lett"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0530","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1021\/am201311c","article-title":"Biocompatible magnetite\/gold nanohybrid contrast agents via green chemistry for MRI and CT bioimaging","volume":"4","author":"Narayanan","year":"2012","journal-title":"ACS Appl Mater Interfaces"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0535","doi-asserted-by":"crossref","first-page":"523","DOI":"10.2217\/nnm.10.23","article-title":"Understanding and overcoming major barriers in cancer nanomedicine","volume":"5","author":"Nie","year":"2010","journal-title":"Nanomedicine"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0540","doi-asserted-by":"crossref","first-page":"2776","DOI":"10.1021\/jp409653t","article-title":"Sorption of gold by naked and thiol-capped magnetite nanoparticles: an XPS approach","volume":"118","author":"Odio","year":"2014","journal-title":"J Phys Chem C"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0545","doi-asserted-by":"crossref","first-page":"R167","DOI":"10.1088\/0022-3727\/36\/13\/201","article-title":"Applications of magnetic nanoparticles in biomedicine","volume":"36","author":"Pankhurst","year":"2003","journal-title":"J Phys D Appl Phys"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0550","doi-asserted-by":"crossref","first-page":"2932","DOI":"10.1002\/ange.200461665","article-title":"One-nanometer-scale size-controlled synthesis of monodisperse magnetic iron oxide nanoparticles","volume":"117","author":"Park","year":"2005","journal-title":"Angew Chem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0555","doi-asserted-by":"crossref","first-page":"125102","DOI":"10.1088\/0957-4484\/24\/12\/125102","article-title":"Thermostable trypsin conjugates immobilized to biogenic magnetite show a high operational stability and remarkable reusability for protein digestion","volume":"24","author":"Pecova","year":"2013","journal-title":"Nanotechnology"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0560","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1477-3155-6-10","article-title":"Capillary electrophoresis for the characterization of quantum dots after non-selective or selective bioconjugation with antibodies for immunoassay","volume":"6","author":"Pereira","year":"2008","journal-title":"J Nanobiotechnol"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0565","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1016\/j.ultsonch.2008.04.014","article-title":"Sonochemical deposition of magnetite on silver nanocrystals","volume":"16","author":"Perkas","year":"2009","journal-title":"Ultrason Sonochem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0570","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1002\/apmc.1976.050530106","article-title":"Chemical transfomation of polymers, XIX. Ion exchange derivatives of bead cellulose","volume":"53","author":"Pe\u0161ka","year":"1976","journal-title":"Angew Macromol Chem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0575","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1039\/B716113A","article-title":"One-step bioengineering of magnetic nanoparticles via a surface diazo transfer\/azide-alkyne click reaction sequence","volume":"5","author":"Polito","year":"2008","journal-title":"Chem Commun"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0580","doi-asserted-by":"crossref","first-page":"619","DOI":"10.3109\/1061186X.2014.910793","article-title":"Tumor-preferential sustained drug release enhances antitumor activity of block copolymer micelles","volume":"22","author":"Ponta","year":"2014","journal-title":"J Drug Target"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0585","doi-asserted-by":"crossref","first-page":"1142","DOI":"10.1039\/c2tb00275b","article-title":"Magnetic nanoclusters with hydrophilic spacing for dual drug delivery and sensitive magnetic resonance imaging","volume":"1","author":"Pothayee","year":"2013","journal-title":"J Mater Chem B"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0590","doi-asserted-by":"crossref","first-page":"4704","DOI":"10.1016\/j.biomaterials.2011.03.039","article-title":"The targeted antibacterial and antifungal properties of magnetic nanocomposite of iron oxide and silver nanoparticles","volume":"32","author":"Prucek","year":"2011","journal-title":"Biomaterials"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0595","doi-asserted-by":"crossref","first-page":"6274","DOI":"10.1039\/b902394a","article-title":"Superparamagnetic iron oxide nanoparticles: from preparations to in vivo MRI applications","volume":"19","author":"Qiao","year":"2009","journal-title":"J Mater Chem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0600","doi-asserted-by":"crossref","first-page":"2939","DOI":"10.1021\/ac500394g","article-title":"Magnetically assisted surface-enhanced Raman scattering selective determination of dopamine in an artificial cerebrospinal fluid and a mouse striatum using Fe3O4\/Ag nanocomposite","volume":"86","author":"Ranc","year":"2014","journal-title":"Anal Chem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0605","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1016\/S0939-6411(98)00038-1","article-title":"Surface-modified biodegradable albumin nano- and microspheres. II: effect of surface charges on in vitro phagocytosis and biodistribution in rats","volume":"46","author":"Roser","year":"1998","journal-title":"Eur J Pharm Biopharm"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0610","doi-asserted-by":"crossref","first-page":"3494","DOI":"10.1039\/C4GC00558A","article-title":"Magnetically recyclable magnetite\u2013palladium (Nanocat-Fe\u2013Pd) nanocatalyst for the Buchwald\u2013Hartwig reaction","volume":"16","author":"Sa","year":"2014","journal-title":"Green Chem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0620","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1186\/1477-044X-2-7","article-title":"Magnetic techniques for the isolation and purification of proteins and peptides","volume":"2","author":"Safarik","year":"2004","journal-title":"BioMagn Res Technol"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0615","first-page":"355","article-title":"Magnetic cation exchange isolation of lysozyme from native hen egg white","volume":"45","author":"Safarik","year":"2007","journal-title":"Food Technol Biotechnol"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0625","doi-asserted-by":"crossref","first-page":"2701","DOI":"10.1021\/cm0603001","article-title":"Bifunctional gold-coated magnetic silica spheres","volume":"18","author":"Salgueirino-Maceira","year":"2006","journal-title":"Chem Mater"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb9000","doi-asserted-by":"crossref","first-page":"130","DOI":"10.1016\/j.ijpharm.2010.12.046","article-title":"Novel magnetic iron oxide nanoparticles coated with poly(ethylene imine)-g-poly(ethylene glycol) for potential biomedical application: synthesis, stability, cytotoxicity and MR imaging","volume":"408","author":"Schweiger","year":"2011","journal-title":"Int J Pharm"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0635","doi-asserted-by":"crossref","first-page":"3453","DOI":"10.1021\/la305048m","article-title":"Multifunctional carboxymethyl cellulose-based magnetic nanovector as a theragnostic system for folate receptor targeted chemotherapy, imaging, and hyperthermia against cancer","volume":"29","author":"Sivakumar","year":"2013","journal-title":"Langmuir"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0645","doi-asserted-by":"crossref","first-page":"122","DOI":"10.2310\/7290.2006.00013","article-title":"\u201cClickable\u201d nanoparticles for targeted imaging","volume":"5","author":"Sun","year":"2006","journal-title":"Mol Imaging"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0640","doi-asserted-by":"crossref","first-page":"1252","DOI":"10.1016\/j.addr.2008.03.018","article-title":"Magnetic nanoparticles in MR imaging and drug delivery","volume":"60","author":"Sun","year":"2008","journal-title":"Adv Drug Deliv Rev"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0650","doi-asserted-by":"crossref","first-page":"135101","DOI":"10.1088\/0957-4484\/20\/13\/135101","article-title":"Thermosensitive liposomes entrapping iron oxide nanoparticles for controllable drug release","volume":"20","author":"Tai","year":"2009","journal-title":"Nanotechnology"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0655","doi-asserted-by":"crossref","first-page":"656","DOI":"10.1016\/j.procbio.2013.03.001","article-title":"Characterization of lactase-conjugated magnetic nanoparticles","volume":"48","author":"Talbert","year":"2013","journal-title":"Process Biochem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0660","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1007\/s11051-009-9749-0","article-title":"Synthesis of magnetic core\u2013shell Fe3O4\u2013Au nanoparticle for biomolecule immobilization and detection","volume":"12","author":"Tamer","year":"2010","journal-title":"J Nanoparticle Res"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0665","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1016\/j.ijpharm.2003.09.050","article-title":"Tumor targeting based on the effect of enhanced permeability and retention (EPR) and the mechanism of receptor-mediated endocytosis (RME)","volume":"277","author":"Tanaka","year":"2004","journal-title":"Int J Pharm"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0670","doi-asserted-by":"crossref","first-page":"221","DOI":"10.2310\/7290.2009.00021","article-title":"Comparative analysis of nanoparticle-antibody conjugations: carbodiimide versus click chemistry","volume":"8","author":"Thorek","year":"2009","journal-title":"Mol Imaging"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0685","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1166\/jnn.2006.183","article-title":"Maghemite nanoparticles by view of Mossbauer spectroscopy","volume":"6","author":"Tucek","year":"2006","journal-title":"J Nanosci Nanotechnol"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0680","doi-asserted-by":"crossref","first-page":"6483","DOI":"10.1021\/cm101967h","article-title":"\u03b5-Fe2O3: an advanced nanomaterial exhibiting giant coercive field, millimeter-wave ferromagnetic resonance, and magnetoelectric coupling","volume":"22","author":"Tucek","year":"2010","journal-title":"Chem Mater"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0675","doi-asserted-by":"crossref","first-page":"7571","DOI":"10.1021\/nn501836x","article-title":"Iron-oxide-supported nanocarbon in lithium-ion batteries, medical, catalytic, and environmental applications","volume":"8","author":"Tucek","year":"2014","journal-title":"ACS Nano"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0690","doi-asserted-by":"crossref","first-page":"11438","DOI":"10.1039\/c3nr02188b","article-title":"Functionalization of PEGylated Fe3O4 magnetic nanoparticles with tetraphosphonate cavitand for biomedical application","volume":"5","author":"Tudisco","year":"2013","journal-title":"Nanoscale"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0700","doi-asserted-by":"crossref","first-page":"6200","DOI":"10.1158\/0008-5472.CAN-09-1157","article-title":"Specific targeting of brain tumors with an optical\/magnetic resonance imaging nanoprobe across the blood\u2013brain barrier","volume":"69","author":"Veiseh","year":"2009","journal-title":"Cancer Res"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0695","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1016\/j.addr.2009.11.002","article-title":"Design and fabrication of magnetic nanoparticles for targeted drug delivery and imaging","volume":"62","author":"Veiseh","year":"2010","journal-title":"Adv Drug Deliv Rev"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0710","doi-asserted-by":"crossref","first-page":"2319","DOI":"10.1007\/s003300100908","article-title":"Superparamagnetic iron oxide contrast agents: physicochemical characteristics and applications in MR imaging","volume":"11","author":"Wang","year":"2001","journal-title":"Eur Radiol"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0705","doi-asserted-by":"crossref","first-page":"2953","DOI":"10.1039\/c3nr05550g","article-title":"One-step synthesis of water-dispersible ultra-small Fe3O4 nanoparticles as contrast agents for T1 and T2 magnetic resonance imaging","volume":"6","author":"Wang","year":"2014","journal-title":"Nanoscale"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0725","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.2214\/ajr.149.6.1161","article-title":"Ferrite-enhanced MR imaging of hepatic lymphoma: an experimental study in rats","volume":"149","author":"Weissleder","year":"1987","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0715","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1148\/radiology.169.2.3174987","article-title":"Superparamagnetic iron oxide: enhanced detection of focal splenic tumors with MR imaging","volume":"169","author":"Weissleder","year":"1988","journal-title":"Radiology"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0720","doi-asserted-by":"crossref","first-page":"167","DOI":"10.2214\/ajr.152.1.167","article-title":"Superparamagnetic iron oxide: pharmacokinetics and toxicity","volume":"152","author":"Weissleder","year":"1989","journal-title":"Am J Roentgenol"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0730","doi-asserted-by":"crossref","first-page":"4346","DOI":"10.1021\/la204740t","article-title":"Insight into serum protein interactions with functionalized magnetic nanoparticles in biological media","volume":"28","author":"Wiogo","year":"2012","journal-title":"Langmuir"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0735","doi-asserted-by":"crossref","first-page":"5608","DOI":"10.1021\/ie2025147","article-title":"Recoverable platinum nanocatalysts immobilized on magnetic spherical polyelectrolyte brushes","volume":"51","author":"Wu","year":"2012","journal-title":"Ind Eng Chem Res"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0740","doi-asserted-by":"crossref","first-page":"20566","DOI":"10.1039\/c2jm34083f","article-title":"Facile synthesis of single-crystalline mesoporous \u03b1-Fe2O3 and Fe3O4 nanorods as anode materials for lithium-ion batteries","volume":"22","author":"Xiao","year":"2012","journal-title":"J Mater Chem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0745","doi-asserted-by":"crossref","first-page":"883","DOI":"10.1021\/ar200044b","article-title":"Surface-engineered magnetic nanoparticle platforms for cancer imaging and therapy","volume":"44","author":"Xie","year":"2011","journal-title":"Acc Chem Res"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0755","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.electacta.2012.03.147","article-title":"Electrochemical biosensors based on magnetic micro\/nano particles","volume":"84","author":"Xu","year":"2012","journal-title":"Electrochim Acta"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0750","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.scitotenv.2012.02.023","article-title":"Use of iron oxide nanomaterials in wastewater treatment: a review","volume":"424","author":"Xu","year":"2012","journal-title":"Sci Total Environ"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0760","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1002\/pola.22372","article-title":"Preparation and characterization of monodisperse superparamagnetic poly (vinylalcohol) beads by reverse spray suspension crosslinking","volume":"46","author":"Yang","year":"2008","journal-title":"J Polym Sci A Polym Chem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0765","doi-asserted-by":"crossref","first-page":"4722","DOI":"10.1158\/1078-0432.CCR-08-3289","article-title":"Receptor-targeted nanoparticles for in vivo imaging of breast cancer","volume":"15","author":"Yang","year":"2009","journal-title":"Clin Cancer Res"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0775","doi-asserted-by":"crossref","first-page":"969","DOI":"10.1021\/cm0111074","article-title":"Iron(III) oxides from thermal processes \u2014 synthesis, structural and magnetic properties, mossbauer spectroscopy characterization, and applications","volume":"14","author":"Zboril","year":"2002","journal-title":"Chem Mater"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0770","doi-asserted-by":"crossref","first-page":"1317","DOI":"10.1021\/cg049748+","article-title":"Iron(III) oxide nanoparticles in the thermally induced oxidative decomposition of Prussian Blue, Fe4[Fe(CN)6]3","volume":"4","author":"Zboril","year":"2004","journal-title":"Cryst Growth Des"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0780","doi-asserted-by":"crossref","first-page":"391","DOI":"10.1002\/adfm.200701211","article-title":"Syntheses, properties, and potential applications of multicomponent magnetic nanoparticles","volume":"18","author":"Zeng","year":"2008","journal-title":"Adv Funct Mater"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0795","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1002\/(SICI)1097-4660(199903)74:3<270::AID-JCTB24>3.0.CO;2-X","article-title":"Magnetically stabilised fluidised bed adsorption: practical benefit of uncoupling bed expansion from fluid velocities in the purification of a recombinant protein from Escherichia coli","volume":"74","author":"Zhang","year":"1999","journal-title":"J Chem Technol Biotechnol"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0785","doi-asserted-by":"crossref","first-page":"1979","DOI":"10.1039\/C4CY00040D","article-title":"A highly efficient and recyclable Fe3O4 magnetic nanoparticle immobilized palladium catalyst for the direct C-2 arylation of indoles with arylboronic acids","volume":"4","author":"Zhang","year":"2014","journal-title":"Catal Sci Technol"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0790","doi-asserted-by":"crossref","first-page":"4212","DOI":"10.1039\/C4NJ00424H","article-title":"Boronic acid functionalized magnetic nanoparticles via thiol\u2013ene click chemistry for selective enrichment of glycoproteins","volume":"38","author":"Zhang","year":"2014","journal-title":"New J Chem R Soc Chem"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0805","doi-asserted-by":"crossref","first-page":"11217","DOI":"10.1021\/la100556p","article-title":"Robust Fe3O4\/SiO2\u2013Pt\/Au\/Pd magnetic nanocatalysts with multifunctional hyperbranched polyglycerol amplifiers","volume":"26","author":"Zhou","year":"2010","journal-title":"Langmuir"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0800","doi-asserted-by":"crossref","first-page":"375102","DOI":"10.1088\/0957-4484\/24\/37\/375102","article-title":"Magnetic tumor targeting of \u03b2-glucosidase immobilized iron oxide nanoparticles","volume":"24","author":"Zhou","year":"2013","journal-title":"Nanotechnology"},{"key":"10.1016\/j.biotechadv.2015.02.003_bb0810","doi-asserted-by":"crossref","first-page":"2062","DOI":"10.1021\/cm404053v","article-title":"Theranostics of epitaxially condensed colloidal nanocrystal clusters, through a soft biomineralization route","volume":"26","author":"Zoppellaro","year":"2014","journal-title":"Chem Mater"}],"container-title":["Biotechnology Advances"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0734975015000282?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0734975015000282?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,11]],"date-time":"2026-05-11T23:26:36Z","timestamp":1778541996000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0734975015000282"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,11]]},"references-count":160,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2015,11]]}},"alternative-id":["S0734975015000282"],"URL":"https:\/\/doi.org\/10.1016\/j.biotechadv.2015.02.003","relation":{},"ISSN":["0734-9750"],"issn-type":[{"value":"0734-9750","type":"print"}],"subject":[],"published":{"date-parts":[[2015,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Tailored functionalization of iron oxide nanoparticles for MRI, drug delivery, magnetic separation and immobilization of biosubstances","name":"articletitle","label":"Article Title"},{"value":"Biotechnology Advances","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biotechadv.2015.02.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}