{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,31]],"date-time":"2026-10-31T20:58:39Z","timestamp":1793480319270,"version":"4.5.0"},"reference-count":72,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,7,1]],"date-time":"2024-07-01T00:00:00Z","timestamp":1719792000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biotechnology Advances"],"published-print":{"date-parts":[[2024,7]]},"DOI":"10.1016\/j.biotechadv.2024.108374","type":"journal-article","created":{"date-parts":[[2024,5,8]],"date-time":"2024-05-08T11:31:48Z","timestamp":1715167908000},"page":"108374","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"special_numbering":"C","title":["Overview of indigo biosynthesis by Flavin-containing Monooxygenases: History, industrialization challenges, and strategies"],"prefix":"10.1016","volume":"73","author":[{"given":"Changxin","family":"Fan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ziqi","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Da","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruihan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yijin","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiacheng","family":"Shi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingyuan","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yifei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Zhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunjun","family":"Yan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.biotechadv.2024.108374_bb0005","series-title":"Assembling membraneless organelles from de novo designed proteins. bioRxiv","author":"Alexander","year":"2023"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0010","doi-asserted-by":"crossref","first-page":"6572","DOI":"10.1073\/pnas.0800859105","article-title":"Revealing the moonlighting role of NADP in the structure of a flavin-containing monooxygenase","volume":"105","author":"Alfieri","year":"2008","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0015","doi-asserted-by":"crossref","first-page":"1637","DOI":"10.1007\/s10529-015-1824-2","article-title":"Characterization of a flavin-containing monooxygenase from Corynebacterium glutamicum and its application to production of indigo and indirubin","volume":"37","author":"Ameria","year":"2015","journal-title":"Biotechnol. Lett."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0020","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1038\/sj.jim.7000228","article-title":"Application of metabolic engineering to improve both the production and use of biotech indigo","volume":"28","author":"Berry","year":"2002","journal-title":"J. Ind. Microbiol. Biotechnol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0025","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1038\/nbt0297-110","article-title":"Biotechnology, bioremediation, and blue genes","volume":"15","author":"Bialy","year":"1997","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0030","doi-asserted-by":"crossref","first-page":"1489","DOI":"10.1038\/s41467-024-45749-3","article-title":"Chemoenzymatic indican for light-driven denim dyeing","volume":"15","author":"Bidart","year":"2024","journal-title":"Nat. Commun."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0035","first-page":"226","article-title":"Cloning of Pseudomonas putida genes responsible for the primary stages of oxidation of naphthalene in Escherichia coli cells","volume":"25","author":"Boronin","year":"1989","journal-title":"Genetika"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0040","doi-asserted-by":"crossref","first-page":"2974","DOI":"10.1021\/ac504535y","article-title":"Human flavin-containing monooxygenase 3 on graphene oxide for drug metabolism screening","volume":"87","author":"Castrignan\u00f2","year":"2015","journal-title":"Anal. Chem."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0045","doi-asserted-by":"crossref","first-page":"17791","DOI":"10.1073\/pnas.1112928108","article-title":"Bacterial flavin-containing monooxygenase is trimethylamine monooxygenase","volume":"108","author":"Chen","year":"2011","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0050","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12934-021-01636-w","article-title":"Development and optimization of a microbial co-culture system for heterologous indigo biosynthesis","volume":"20","author":"Chen","year":"2021","journal-title":"Microb. Cell Factories"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0055","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1007\/s00284-016-1055-3","article-title":"Enhancing indigo production by over-expression of the styrene monooxygenase in Pseudomonas putida","volume":"73","author":"Cheng","year":"2016","journal-title":"Curr. Microbiol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0060","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1016\/j.jbiotec.2023.03.012","article-title":"Strategy for efficiently utilizing Escherichia coli cells producing isobutanol by combining isobutanol and indigo production systems","volume":"367","author":"Cho","year":"2023","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0065","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2023.111724","article-title":"Tryptophan-based in vivo coloring of polyhydroxybutyrate through co-production with indigo and effect on the properties of polymer","volume":"220","author":"Cho","year":"2023","journal-title":"Dyes Pigments"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0070","doi-asserted-by":"crossref","first-page":"930","DOI":"10.1016\/S0006-291X(03)01087-8","article-title":"A novel flavin-containing monooxygenase from Methylophaga sp. strain SK1 and its indigo synthesis in Escherichia coli","volume":"306","author":"Choi","year":"2003","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0075","doi-asserted-by":"crossref","first-page":"290","DOI":"10.3390\/suschem1030019","article-title":"Biocatalyzed sulfoxidation in presence of deep eutectic solvents","volume":"1","author":"De Gonzalo","year":"2020","journal-title":"Sustain. Chem."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0080","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1271\/bbb.62.1075","article-title":"Effects of organic solvents on indigo formation by Pseudomonas sp. strain ST-200 grown with high levels of indole","volume":"62","author":"Doukyu","year":"1998","journal-title":"Biosci. Biotechnol. Biochem."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0085","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1007\/s00253-001-0919-y","article-title":"Isolation of an Acinetobacter sp. ST-550 which produces a high level of indigo in a water-organic solvent two-phase system containing high levels of indole","volume":"58","author":"Doukyu","year":"2002","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0090","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1007\/s00253-002-1187-1","article-title":"Indigo production by Escherichia coli carrying the phenol hydroxylase gene from Acinetobacter sp. strain ST-550 in a water\u2013organic solvent two-phase system","volume":"60","author":"Doukyu","year":"2003","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0095","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1016\/j.jbiotec.2017.12.026","article-title":"Metabolic engineering of Escherichia coli for the production of indirubin from glucose","volume":"267","author":"Du","year":"2018","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0100","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1126\/science.6353574","article-title":"Expression of naphthalene oxidation genes in Escherichia coli results in the biosynthesis of indigo","volume":"222","author":"Ensley","year":"1983","journal-title":"Science"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0105","doi-asserted-by":"crossref","first-page":"9832","DOI":"10.1073\/pnas.0602398103","article-title":"Mechanism of action of a flavin-containing monooxygenase","volume":"103","author":"Eswaramoorthy","year":"2006","journal-title":"Proc. Natl. Acad. Sci."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.enzmictec.2020.109692","article-title":"Production of indigo through the use of a dual-function substrate and a bifunctional fusion enzyme","volume":"142","author":"Fabara","year":"2020","journal-title":"Enzym. Microb. Technol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0115","article-title":"AutoDock docking results between mFMO and indole","volume":"v2","author":"Fan","year":"2023","journal-title":"Mendeley Data"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0120","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1186\/s13068-018-1077-0","article-title":"Techno-economic analysis of the industrial production of a low-cost enzyme using E. Coli: the case of recombinant \u03b2-glucosidase","volume":"11","author":"Ferreira","year":"2018","journal-title":"Biotechnol. Biofuels"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0125","doi-asserted-by":"crossref","first-page":"6701","DOI":"10.1021\/acs.biochem.8b01052","article-title":"The extreme structural plasticity in the CYP153 subfamily of P450s directs development of designer hydroxylases","volume":"57","author":"Fiorentini","year":"2018","journal-title":"Biochemistry"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0130","doi-asserted-by":"crossref","first-page":"543","DOI":"10.1038\/s41467-023-36073-3","article-title":"A split ribozyme that links detection of a native RNA to orthogonal protein outputs","volume":"14","author":"Gambill","year":"2023","journal-title":"Nat. Commun."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0135","doi-asserted-by":"crossref","first-page":"1931","DOI":"10.1002\/cbic.201600431","article-title":"A catalytic nanoreactor based on in vivo encapsulation of multiple enzymes in an engineered protein nanocompartment","volume":"17","author":"Giessen","year":"2016","journal-title":"ChemBioChem"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0140","first-page":"7263","article-title":"Identification of a novel oxygenase capable of regiospecific hydroxylation of d-limonene into (+)-trans-carveol","volume":"72","author":"Groeneveld","year":"2016","journal-title":"Mod. Dev. Biotransform."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0145","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jbiotec.2023.02.008","article-title":"Enhanced production of bio-indigo in engineered Escherichia coli, reinforced by cyclopropane-fatty acid-acyl-phospholipid synthase from psychrophilic Pseudomonas sp. B14-6","author":"Ham","year":"2023","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0150","doi-asserted-by":"crossref","first-page":"617","DOI":"10.1016\/j.enzmictec.2008.02.004","article-title":"Optimization of bio-indigo production by recombinant E. Coli harboring fmo gene","volume":"42","author":"Han","year":"2008","journal-title":"Enzym. Microb. Technol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0155","doi-asserted-by":"crossref","first-page":"788","DOI":"10.1016\/j.procbio.2010.10.015","article-title":"Bio-indigo production in two different fermentation systems using recombinant Escherichia coli cells harboring a flavin-containing monooxygenase gene (fmo)","volume":"46","author":"Han","year":"2011","journal-title":"Process Biochem."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0160","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.jbiotec.2012.08.015","article-title":"Enhanced indirubin production in recombinant Escherichia coli harboring a flavin-containing monooxygenase gene by cysteine supplementation","volume":"164","author":"Han","year":"2013","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0165","doi-asserted-by":"crossref","first-page":"939","DOI":"10.1515\/hsz-2019-0109","article-title":"Indigoid dyes by group E monooxygenases: mechanism and biocatalysis","volume":"400","author":"Heine","year":"2019","journal-title":"Biol. Chem."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0170","doi-asserted-by":"crossref","first-page":"256","DOI":"10.1038\/nchembio.2552","article-title":"Employing a biochemical protecting group for a sustainable indigo dyeing strategy","volume":"14","author":"Hsu","year":"2018","journal-title":"Nat. Chem. Biol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0175","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/j.bbrc.2020.11.112","article-title":"An indigo-producing plant, Polygonum tinctorium, possesses a flavin-containing monooxygenase capable of oxidizing indole","volume":"534","author":"Inoue","year":"2021","journal-title":"Biochem. Biophys. Res. Commun."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.ijbiomac.2023.123863","article-title":"Genetically engineered blue silkworm capable of synthesizing natural blue pigment","volume":"235","author":"Jia","year":"2023","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0185","first-page":"656","article-title":"Protein engineering of flavin-containing monooxygenase from Corynebacterium glutamicum for improved production of indigo and indirubin","volume":"28","author":"Jung","year":"2018","journal-title":"\uc0dd\uba85\uacfc\ud559\ud68c\uc9c0"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0190","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/1574-6968.12135","article-title":"Indole toxicity involves the inhibition of adenosine triphosphate production and protein folding in Pseudomonas putida","volume":"343","author":"Kim","year":"2013","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0195","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/j.dyepig.2017.01.029","article-title":"Biosynthesis of indigo in Escherichia coli expressing self-sufficient CYP102A from Streptomyces cattleya","volume":"140","author":"Kim","year":"2017","journal-title":"Dyes Pigments"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0200","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1016\/j.bbapap.2017.08.002","article-title":"In vitro characterization of CYP102G4 from Streptomyces cattleya: a self-sufficient P450 naturally producing indigo","volume":"1866","author":"Kim","year":"2018","journal-title":"BBA-Proteins Proteom."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0205","doi-asserted-by":"crossref","first-page":"9539","DOI":"10.1021\/acscatal.9b02613","article-title":"Elucidating cysteine-assisted synthesis of indirubin by a flavin-containing monooxygenase","volume":"9","author":"Kim","year":"2019","journal-title":"ACS Catal."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0210","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1186\/s40643-023-00626-7","article-title":"Production of indigo by recombinant bacteria","volume":"10","author":"Linke","year":"2023","journal-title":"Bioresour. Bioprocess."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0215","doi-asserted-by":"crossref","first-page":"1755","DOI":"10.1007\/s00253-018-09579-w","article-title":"Characterization of a thermostable flavin-containing monooxygenase from Nitrincola lacisaponensis (NiFMO)","volume":"103","author":"Lon\u010dar","year":"2019","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0220","doi-asserted-by":"crossref","first-page":"6148","DOI":"10.3390\/ijms20246148","article-title":"Structure-based redesign of a self-sufficient flavin-containing monooxygenase towards indigo production","volume":"20","author":"Lon\u010dar","year":"2019","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0225","doi-asserted-by":"crossref","first-page":"125","DOI":"10.3390\/metabo10040125","article-title":"Enzyme assembly for compartmentalized metabolic flux control","volume":"10","author":"Lv","year":"2020","journal-title":"Metabolites"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0230","doi-asserted-by":"crossref","first-page":"208","DOI":"10.1186\/s12934-021-01698-w","article-title":"Recombinant expression of insoluble enzymes in Escherichia coli: a systematic review of experimental design and its manufacturing implications","volume":"20","author":"Mital","year":"2021","journal-title":"Microb. Cell Factories"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0235","doi-asserted-by":"crossref","first-page":"381","DOI":"10.1038\/nbt0393-381","article-title":"Construction of metabolic operons catalyzing the de novo biosynthesis of indigo in Escherichia coli","volume":"11","author":"Murdock","year":"1993","journal-title":"Biotechnol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0240","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1021\/acssynbio.6b00141","article-title":"Synthetic lipid-containing scaffolds enhance production by colocalizing enzymes","volume":"5","author":"Myhrvold","year":"2016","journal-title":"ACS Synth. Biol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0245","doi-asserted-by":"crossref","first-page":"502","DOI":"10.3390\/foods12030502","article-title":"A combinational optimization method for efficient production of indigo by the recombinant Escherichia coli with expression of monooxygenase and malate dehydrogenase","volume":"12","author":"Pan","year":"2023","journal-title":"Foods"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0250","doi-asserted-by":"crossref","first-page":"1616","DOI":"10.1007\/s12010-009-8638-4","article-title":"Biosynthesis of indigo dye by newly isolated naphthalene-degrading strain Pseudomonas sp. HOB1 and its application in dyeing cotton fabric","volume":"160","author":"Pathak","year":"2010","journal-title":"Appl. Biochem. Biotechnol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0255","series-title":"Ullmann\u2019s Encyclopedia of Industrial Chemistry","first-page":"1","article-title":"Indigo and indigo colorants","author":"Paul","year":"2021"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0260","doi-asserted-by":"crossref","DOI":"10.1016\/j.bioorg.2021.105561","article-title":"The role of remote flavin adenine dinucleotide pieces in the oxidative decarboxylation catalyzed by salicylate hydroxylase","volume":"119","author":"Pereira","year":"2022","journal-title":"Bioorg. Chem."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0265","series-title":"Directed Evolution of a Sulfoxidation Biocatalyst (Ph.D.). ProQuest Diss","author":"Polyzos","year":"2003"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0270","doi-asserted-by":"crossref","DOI":"10.1371\/annotation\/087266ef-a19f-4224-a7c2-119d1b363331","article-title":"Characterization of a novel phenol hydroxylase in indoles biotranformation from a strain Arthrobacter sp. W1","volume":"7","author":"Qu","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0275","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1186\/1475-2859-10-10","article-title":"High cell density cultivation of Escherichia coli K4 in a microfiltration bioreactor: a step towards improvement of chondroitin precursor production","volume":"10","author":"Restaino","year":"2011","journal-title":"Microb. Cell Factories"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0280","doi-asserted-by":"crossref","first-page":"1337","DOI":"10.1039\/c0ob00988a","article-title":"Exploring the biocatalytic scope of a bacterial flavin-containing monooxygenase","volume":"9","author":"Rioz-Mart\u00ednez","year":"2011","journal-title":"Org. Biomol. Chem."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0285","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1007\/s00253-004-1698-z","article-title":"Protein engineering of toluene ortho-monooxygenase of Burkholderia cepacia G4 for regiospecific hydroxylation of indole to form various indigoid compounds","volume":"66","author":"Rui","year":"2005","journal-title":"Appl. Microbiol. Biotechnol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0290","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1002\/ciuz.19970310304","article-title":"Indigo \u2013 100 Jahre industrielle Synthese","volume":"31","author":"Schmidt","year":"1997","journal-title":"Chem. Unserer Zeit"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0295","doi-asserted-by":"crossref","first-page":"5404","DOI":"10.1002\/chem.202005191","article-title":"Novel arylindigoids by late-stage derivatization of biocatalytically synthesized dibromoindigo","volume":"27","author":"Schnepel","year":"2021","journal-title":"Chem. Eur. J."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0300","first-page":"215","article-title":"Modern industrial and pharmacological applications of indigo dye and its derivatives--a review","volume":"71","author":"Stasiak","year":"2014","journal-title":"Acta Pol. Pharm."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0305","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1111\/j.1574-6968.1989.tb03352.x","article-title":"Cloning and expression in Escherichia coli of the toluene dioxygenase gene from Pseudomonas putida NCIB11767","volume":"57","author":"Stephens","year":"1989","journal-title":"FEMS Microbiol. Lett."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0310","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1186\/s40643-022-00559-7","article-title":"Structure-guided engineering of a flavin-containing monooxygenase for the efficient production of indirubin","volume":"9","author":"Sun","year":"2022","journal-title":"Bioresour. Bioprocess."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0315","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/s12934-019-1065-5","article-title":"Asp305Gly mutation improved the activity and stability of the styrene monooxygenase for efficient epoxide production in Pseudomonas putida KT2440","volume":"18","author":"Tan","year":"2019","journal-title":"Microb. Cell Factories"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0320","series-title":"Industrial Biotechnology","first-page":"149","article-title":"Industrial biotechnology: Escherichia coli as a host","author":"Theisen","year":"2017"},{"key":"10.1016\/j.biotechadv.2024.108374_bb0325","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/j.jbiotec.2006.03.044","article-title":"Flavoprotein monooxygenases, a diverse class of oxidative biocatalysts","volume":"124","author":"van Berkel","year":"2006","journal-title":"J. Biotechnol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0330","doi-asserted-by":"crossref","first-page":"1891","DOI":"10.1007\/s10295-011-1034-4","article-title":"Increasing recombinant protein production in Escherichia coli through metabolic and genetic engineering","volume":"38","author":"Waegeman","year":"2011","journal-title":"J. Ind. Microbiol. Biotechnol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0335","doi-asserted-by":"crossref","DOI":"10.1038\/s41587-024-02194-3","article-title":"Self-pigmenting textiles grown from cellulose-producing bacteria with engineered tyrosinase expression","author":"Walker","year":"2024","journal-title":"Nat. Biotechnol."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0340","doi-asserted-by":"crossref","first-page":"4578","DOI":"10.1021\/acs.chemrev.0c00002","article-title":"Modern Stereoselective synthesis of chiral sulfinyl compounds","volume":"120","author":"Wojaczy\u0144ska","year":"2020","journal-title":"Chem. Rev."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0345","doi-asserted-by":"crossref","DOI":"10.1016\/j.bej.2021.108096","article-title":"Protein engineering design from directed evolution to de novo synthesis","volume":"174","author":"Xiong","year":"2021","journal-title":"Biochem. Eng. J."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0350","doi-asserted-by":"crossref","first-page":"113112","DOI":"10.1016\/j.biopha.2022.113112","article-title":"Pharmacological properties of indirubin and its derivatives","volume":"151","author":"Yang","year":"2022","journal-title":"Biomed. Pharmacother."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0355","doi-asserted-by":"crossref","DOI":"10.1016\/j.bej.2023.109064","article-title":"Key residues identified by random mutagenesis enhanced indole hydroxylation efficiency of the flavin-containing monooxygenase from Corynebacterium glutamicum","volume":"199","author":"Yang","year":"2023","journal-title":"Biochem. Eng. J."},{"key":"10.1016\/j.biotechadv.2024.108374_bb0360","doi-asserted-by":"crossref","DOI":"10.1016\/j.dyepig.2023.111466","article-title":"Production of bio-indigo dye by surmounting its physical and chemical insoluble nature","volume":"218","author":"Yuk","year":"2023","journal-title":"Dyes Pigments"}],"container-title":["Biotechnology Advances"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0734975024000685?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0734975024000685?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,6,5]],"date-time":"2024-06-05T19:40:59Z","timestamp":1717616459000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0734975024000685"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7]]},"references-count":72,"alternative-id":["S0734975024000685"],"URL":"https:\/\/doi.org\/10.1016\/j.biotechadv.2024.108374","relation":{},"ISSN":["0734-9750"],"issn-type":[{"value":"0734-9750","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Overview of indigo biosynthesis by Flavin-containing Monooxygenases: History, industrialization challenges, and strategies","name":"articletitle","label":"Article Title"},{"value":"Biotechnology Advances","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.biotechadv.2024.108374","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"108374"}}