{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,15]],"date-time":"2026-08-15T09:59:01Z","timestamp":1786787941693,"version":"build-2736575974"},"reference-count":64,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,11,24]],"date-time":"2022-11-24T00:00:00Z","timestamp":1669248000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100005795","name":"Chang Gung Medical Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100005795","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100011892","name":"Kaohsiung Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CMRPG8G1051"],"award-info":[{"award-number":["CMRPG8G1051"]}],"id":[{"id":"10.13039\/501100011892","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004606","name":"Chang Gung Medical Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004606","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Biomedical Journal"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.bj.2022.11.004","type":"journal-article","created":{"date-parts":[[2022,11,25]],"date-time":"2022-11-25T21:50:55Z","timestamp":1669413055000},"page":"100571","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"title":["Effect of three clinical therapies on cytokines modulation in the hip articular cartilage and bone improvement in rat early osteonecrosis of the femoral head"],"prefix":"10.1016","volume":"46","author":[{"given":"Shan-Ling","family":"Hsu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shun-Wun","family":"Jhan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chieh-Cheng","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-No","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kay L.H.","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-En Aurea","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hung-Wen","family":"Chiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3667-2741","authenticated-orcid":false,"given":"Jai-Hong","family":"Cheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.bj.2022.11.004_bib1","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1302\/2058-5241.4.180036","article-title":"Osteonecrosis of the femoral head: pathophysiology and current concepts of treatment","volume":"4","author":"Petek","year":"2019","journal-title":"EFORT Open Rev"},{"key":"10.1016\/j.bj.2022.11.004_bib2","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1016\/j.jot.2019.12.004","article-title":"Guidelines for clinical diagnosis and treatment of osteonecrosis of the femoral head in adults (2019 version)","volume":"21","author":"Zhao","year":"2020","journal-title":"J Orthop Translat"},{"issue":"1","key":"10.1016\/j.bj.2022.11.004_bib3","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1007\/s00402-013-1885-4","article-title":"Core decompression in combination with nano-hydroxyapatite\/polyamide 66 rod for the treatment of osteonecrosis of the femoral head","volume":"134","author":"Yang","year":"2014","journal-title":"Arch Orthop Trauma Surg"},{"issue":"Pt B","key":"10.1016\/j.bj.2022.11.004_bib4","doi-asserted-by":"crossref","first-page":"184","DOI":"10.1016\/j.ijsu.2015.06.080","article-title":"Extracorporeal shockwave therapy for avascular necrosis of femoral head","volume":"24","author":"Wang","year":"2015","journal-title":"Int J Surg"},{"issue":"1","key":"10.1016\/j.bj.2022.11.004_bib5","doi-asserted-by":"crossref","first-page":"306","DOI":"10.1186\/s13018-019-1359-7","article-title":"The efficacy and safety of core decompression for the treatment of femoral head necrosis: a systematic review and meta-analysis","volume":"14","author":"Hua","year":"2019","journal-title":"J Orthop Surg Res"},{"issue":"1","key":"10.1016\/j.bj.2022.11.004_bib6","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1186\/s13018-021-02246-3","article-title":"Long-term survival and clinical outcomes of non-vascularized autologous and allogeneic fibular grafts are comparable for treating osteonecrosis of the femoral head","volume":"16","author":"Jie","year":"2021","journal-title":"J Orthop Surg Res"},{"key":"10.1016\/j.bj.2022.11.004_bib7","doi-asserted-by":"crossref","DOI":"10.1155\/2017\/1732638","article-title":"Hip osteonecrosis is associated with increased plasma IL-33 level","volume":"2017","author":"Ma","year":"2017","journal-title":"Mediat Inflamm"},{"issue":"3","key":"10.1016\/j.bj.2022.11.004_bib8","doi-asserted-by":"crossref","first-page":"283","DOI":"10.5603\/EP.a2018.0031","article-title":"Th17 and IL-17 exhibit higher levels in osteonecrosis of the femoral head and have a positive correlation with severity of pain","volume":"69","author":"Zou","year":"2018","journal-title":"Endokrynol Pol"},{"issue":"10","key":"10.1016\/j.bj.2022.11.004_bib9","doi-asserted-by":"crossref","DOI":"10.1002\/cti2.1187","article-title":"Blockade of IL-33 signalling attenuates osteoarthritis","volume":"9","author":"He","year":"2020","journal-title":"Clin Transl Immunol"},{"issue":"5","key":"10.1016\/j.bj.2022.11.004_bib10","doi-asserted-by":"crossref","first-page":"921","DOI":"10.1038\/mi.2012.130","article-title":"Potential autocrine regulation of interleukin-33\/ST2 signaling of dendritic cells in allergic inflammation","volume":"6","author":"Su","year":"2013","journal-title":"Mucosal Immunol"},{"key":"10.1016\/j.bj.2022.11.004_bib11","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2021\/9915877","article-title":"Extracorporeal shockwave therapy modulates the expressions of proinflammatory cytokines IL33 and IL17A, and their receptors ST2 and IL17RA, within the articular cartilage in early avascular necrosis of the femoral head in a rat model","volume":"2021","author":"Cheng","year":"2021","journal-title":"Mediat Inflamm"},{"issue":"6","key":"10.1016\/j.bj.2022.11.004_bib12","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1007\/s00264-010-1048-y","article-title":"Concentrated autologous bone marrow aspirate transplantation treatment for corticosteroid-induced osteonecrosis of the femoral head in systemic lupus erythematosus","volume":"35","author":"Yoshioka","year":"2011","journal-title":"Int Orthop"},{"issue":"6","key":"10.1016\/j.bj.2022.11.004_bib13","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1159\/000329502","article-title":"Treatment of osteonecrosis of the femoral head with VEGF165 transgenic bone marrow mesenchymal stem cells in mongrel dogs","volume":"195","author":"Hang","year":"2012","journal-title":"Cells Tissues Organs"},{"issue":"405","key":"10.1016\/j.bj.2022.11.004_bib14","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1097\/00003086-200212000-00003","article-title":"Treatment of osteonecrosis with autologous bone marrow grafting","author":"Hernigou","year":"2002","journal-title":"Clin Orthop Relat Res"},{"key":"10.1016\/j.bj.2022.11.004_bib15","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1186\/1471-2474-15-156","article-title":"Stem cell therapy for the treatment of early stage avascular necrosis of the femoral head: a systematic review","volume":"15","author":"Lau","year":"2014","journal-title":"BMC Musculoskelet Disord"},{"issue":"2","key":"10.1016\/j.bj.2022.11.004_bib16","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1634\/stemcells.21-2-190","article-title":"Multipotential mesenchymal stem cells from femoral bone marrow near the site of osteonecrosis","volume":"21","author":"Lee","year":"2003","journal-title":"Stem Cell"},{"issue":"5","key":"10.1016\/j.bj.2022.11.004_bib17","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1016\/S0736-0266(02)00018-9","article-title":"Multilineage mesenchymal differentiation potential of human trabecular bone-derived cells","volume":"20","author":"Noth","year":"2002","journal-title":"J Orthop Res"},{"issue":"10","key":"10.1016\/j.bj.2022.11.004_bib18","doi-asserted-by":"crossref","first-page":"822","DOI":"10.1002\/term.489","article-title":"Co-culturing mesenchymal stem cells from bone marrow and periosteum enhances osteogenesis and neovascularization of tissue-engineered bone","volume":"6","author":"Chen","year":"2012","journal-title":"J Tissue Eng Regen Med"},{"issue":"2","key":"10.1016\/j.bj.2022.11.004_bib19","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1089\/107632701300062859","article-title":"Multilineage cells from human adipose tissue: implications for cell-based therapies","volume":"7","author":"Zuk","year":"2001","journal-title":"Tissue Eng"},{"issue":"12","key":"10.1016\/j.bj.2022.11.004_bib20","doi-asserted-by":"crossref","first-page":"4279","DOI":"10.1091\/mbc.e02-02-0105","article-title":"Human adipose tissue is a source of multipotent stem cells","volume":"13","author":"Zuk","year":"2002","journal-title":"Mol Biol Cell"},{"issue":"8","key":"10.1016\/j.bj.2022.11.004_bib21","doi-asserted-by":"crossref","first-page":"1928","DOI":"10.1002\/1529-0131(200108)44:8<1928::AID-ART331>3.0.CO;2-P","article-title":"Multipotent mesenchymal stem cells from adult human synovial membrane","volume":"44","author":"De Bari","year":"2001","journal-title":"Arthritis Rheum"},{"issue":"3","key":"10.1016\/j.bj.2022.11.004_bib22","doi-asserted-by":"crossref","first-page":"487","DOI":"10.1590\/S1807-59322011000300022","article-title":"Periosteum as a source of mesenchymal stem cells: the effects of TGF-beta3 on chondrogenesis","volume":"66","author":"Mara","year":"2011","journal-title":"Clinics"},{"issue":"7","key":"10.1016\/j.bj.2022.11.004_bib23","doi-asserted-by":"crossref","first-page":"1653","DOI":"10.1161\/01.ATV.0000222982.55731.f1","article-title":"Fibrin and activated platelets cooperatively guide stem cells to a vascular injury and promote differentiation towards an endothelial cell phenotype","volume":"26","author":"de Boer","year":"2006","journal-title":"Arterioscler Thromb Vasc Biol"},{"issue":"8","key":"10.1016\/j.bj.2022.11.004_bib24","doi-asserted-by":"crossref","first-page":"3792","DOI":"10.1096\/fj.13-247965","article-title":"Role of donor and host cells in muscle-derived stem cell-mediated bone repair: differentiation vs. paracrine effects","volume":"28","author":"Gao","year":"2014","journal-title":"FASEB J"},{"issue":"5","key":"10.1016\/j.bj.2022.11.004_bib25","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1590\/S0102-86502010000500006","article-title":"Successful transplant of mesenchymal stem cells in induced osteonecrosis of the ovine femoral head: preliminary results","volume":"25","author":"Feitosa","year":"2010","journal-title":"Acta Cir Bras"},{"issue":"6","key":"10.1016\/j.bj.2022.11.004_bib26","doi-asserted-by":"crossref","first-page":"1153","DOI":"10.2106\/00004623-200406000-00006","article-title":"Treatment of osteonecrosis of the femoral head with implantation of autologous bone-marrow cells. A pilot study","volume":"86","author":"Gangji","year":"2004","journal-title":"J Bone Jt Surg Am"},{"issue":"6","key":"10.1016\/j.bj.2022.11.004_bib27","doi-asserted-by":"crossref","first-page":"685","DOI":"10.1016\/j.jbspin.2009.04.002","article-title":"The effect of bone marrow mononuclear cells on vascularization and bone regeneration in steroid-induced osteonecrosis of the femoral head","volume":"76","author":"Sun","year":"2009","journal-title":"Jt Bone Spine"},{"issue":"5","key":"10.1016\/j.bj.2022.11.004_bib28","doi-asserted-by":"crossref","first-page":"1005","DOI":"10.1016\/j.bone.2011.07.032","article-title":"Autologous bone marrow cell implantation in the treatment of non-traumatic osteonecrosis of the femoral head: five year follow-up of a prospective controlled study","volume":"49","author":"Gangji","year":"2011","journal-title":"Bone"},{"issue":"4","key":"10.1016\/j.bj.2022.11.004_bib29","doi-asserted-by":"crossref","first-page":"442","DOI":"10.1002\/jor.20759","article-title":"Fate of mesenchymal stem cells transplanted to osteonecrosis of femoral head","volume":"27","author":"Yan","year":"2009","journal-title":"J Orthop Res"},{"key":"10.1016\/j.bj.2022.11.004_bib30","doi-asserted-by":"crossref","first-page":"11","DOI":"10.1186\/1749-799X-7-11","article-title":"Extracorporeal shockwave therapy in musculoskeletal disorders","volume":"7","author":"Wang","year":"2012","journal-title":"J Orthop Surg Res"},{"issue":"9","key":"10.1016\/j.bj.2022.11.004_bib31","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1007\/s00402-007-0530-5","article-title":"Treatment of osteonecrosis of the hip: comparison of extracorporeal shockwave with shockwave and alendronate","volume":"128","author":"Wang","year":"2008","journal-title":"Arch Orthop Trauma Surg"},{"issue":"4","key":"10.1016\/j.bj.2022.11.004_bib32","first-page":"367","article-title":"Shockwaves enhance the osteogenetic gene expression in marrow stromal cells from hips with osteonecrosis","volume":"34","author":"Yin","year":"2011","journal-title":"Chang Gung Med J"},{"key":"10.1016\/j.bj.2022.11.004_bib33","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1097\/00003086-200106000-00016","article-title":"High-energy shock wave treatment of femoral head necrosis in adults","volume":"387","author":"Ludwig","year":"2001","journal-title":"Clin Orthop Relat Res"},{"issue":"40","key":"10.1016\/j.bj.2022.11.004_bib34","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000022598","article-title":"Extracorporeal shockwave therapy combined with multiple drilling and intramedullary drug injection for treating early-stage femur head necrosis","volume":"99","author":"Li","year":"2020","journal-title":"Medicine"},{"issue":"3","key":"10.1016\/j.bj.2022.11.004_bib35","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1006\/bbrc.2001.5654","article-title":"Physical shock wave mediates membrane hyperpolarization and Ras activation for osteogenesis in human bone marrow stromal cells","volume":"287","author":"Wang","year":"2001","journal-title":"Biochem Biophys Res Commun"},{"issue":"3","key":"10.1016\/j.bj.2022.11.004_bib36","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1302\/0301-620X.84B3.0840457","article-title":"Extracorporeal shock wave promotes growth and differentiation of bone-marrow stromal cells towards osteoprogenitors associated with induction of TGF-beta1","volume":"84","author":"Wang","year":"2002","journal-title":"J Bone Jt Surg Br"},{"issue":"6","key":"10.1016\/j.bj.2022.11.004_bib37","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1359\/JBMR.040121","article-title":"Shockwave stimulates oxygen radical-mediated osteogenesis of the mesenchymal cells from human umbilical cord blood","volume":"19","author":"Wang","year":"2004","journal-title":"J Bone Miner Res"},{"issue":"1","key":"10.1016\/j.bj.2022.11.004_bib38","first-page":"62","article-title":"Effect of extracorporeal shock wave on proliferation and differentiation of equine adipose tissue-derived mesenchymal stem cells in vitro","volume":"2","author":"Raabe","year":"2013","journal-title":"Am J Stem Cells"},{"issue":"12","key":"10.1016\/j.bj.2022.11.004_bib39","doi-asserted-by":"crossref","first-page":"1666","DOI":"10.1016\/j.jcyt.2014.07.005","article-title":"In vitro extracorporeal shock wave treatment enhances stemness and preserves multipotency of rat and human adipose-derived stem cells","volume":"16","author":"Schuh","year":"2014","journal-title":"Cytotherapy"},{"issue":"4","key":"10.1016\/j.bj.2022.11.004_bib40","doi-asserted-by":"crossref","first-page":"1217","DOI":"10.3390\/ijms21041217","article-title":"Shockwave therapy combined with autologous adipose-derived mesenchymal stem cells is better than with human umbilical cord Wharton\u2019s jelly-derived mesenchymal stem cells on knee osteoarthritis","volume":"21","author":"Hsu","year":"2020","journal-title":"Int J Mol Sci"},{"issue":"5","key":"10.1016\/j.bj.2022.11.004_bib41","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0195891","article-title":"Adipose-derived mesenchymal stem cells (AdMSC) for the treatment of secondary-progressive multiple sclerosis: a triple blinded, placebo controlled, randomized phase I\/II safety and feasibility study","volume":"13","author":"Fern\u00e1ndez","year":"2018","journal-title":"PLoS One"},{"issue":"4","key":"10.1016\/j.bj.2022.11.004_bib42","doi-asserted-by":"crossref","first-page":"318","DOI":"10.3390\/ph14040318","article-title":"Autologous adipose-derived mesenchymal stem cells combined with shockwave therapy synergistically ameliorates the osteoarthritic pathological factors in knee joint","volume":"14","author":"Cheng","year":"2021","journal-title":"Pharmaceuticals"},{"issue":"4","key":"10.1016\/j.bj.2022.11.004_bib43","doi-asserted-by":"crossref","first-page":"e5897","DOI":"10.1097\/MD.0000000000005897","article-title":"Extracorporeal shockwave therapy in osteonecrosis of femoral head","volume":"96","author":"Zhang","year":"2017","journal-title":"Medicine"},{"issue":"1","key":"10.1016\/j.bj.2022.11.004_bib44","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1007\/s00402-009-0918-5","article-title":"Cocktail therapy for femoral head necrosis of the hip","volume":"130","author":"Hsu","year":"2010","journal-title":"Arch Orthop Trauma Surg"},{"issue":"1","key":"10.1016\/j.bj.2022.11.004_bib45","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/s13287-018-0805-5","article-title":"Radial shockwave treatment promotes human mesenchymal stem cell self-renewal and enhances cartilage healing","volume":"9","author":"Zhang","year":"2018","journal-title":"Stem Cell Res Ther"},{"issue":"9","key":"10.1016\/j.bj.2022.11.004_bib46","doi-asserted-by":"crossref","first-page":"1079","DOI":"10.1016\/j.jcyt.2017.05.010","article-title":"Improvement of adipose tissue-derived cells by low-energy extracorporeal shock wave therapy","volume":"19","author":"Priglinger","year":"2017","journal-title":"Cytotherapy"},{"issue":"1","key":"10.1016\/j.bj.2022.11.004_bib47","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1038\/s41536-021-00122-6","article-title":"Heterogeneity of mesenchymal stem cells in cartilage regeneration: from characterization to application","volume":"6","author":"Zha","year":"2021","journal-title":"NPJ Regen Med"},{"issue":"4","key":"10.1016\/j.bj.2022.11.004_bib48","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1615\/CritRevEukaryotGeneExpr.2018023572","article-title":"Bone marrow- and adipose tissue-derived mesenchymal stem cells: characterization, differentiation, and applications in cartilage tissue engineering","volume":"28","author":"Li","year":"2018","journal-title":"Crit Rev Eukaryot Gene Expr"},{"issue":"5","key":"10.1016\/j.bj.2022.11.004_bib49","doi-asserted-by":"crossref","first-page":"560","DOI":"10.1038\/nbt958","article-title":"Adipose-derived adult stromal cells heal critical-size mouse calvarial defects","volume":"22","author":"Cowan","year":"2004","journal-title":"Nat Biotechnol"},{"issue":"6","key":"10.1016\/j.bj.2022.11.004_bib50","doi-asserted-by":"crossref","first-page":"9314","DOI":"10.3390\/ijms15069314","article-title":"Adipose-derived stem cells: a review of signaling networks governing cell fate and regenerative potential in the context of craniofacial and long bone skeletal repair","volume":"15","author":"Senarath-Yapa","year":"2014","journal-title":"Int J Mol Sci"},{"issue":"17","key":"10.1016\/j.bj.2022.11.004_bib51","doi-asserted-by":"crossref","first-page":"5105","DOI":"10.7150\/thno.33904","article-title":"Enrichment of CD146+ adipose-derived stem cells in combination with articular cartilage extracellular matrix scaffold promotes cartilage regeneration","volume":"9","author":"Li","year":"2019","journal-title":"Theranostics"},{"issue":"39","key":"10.1016\/j.bj.2022.11.004_bib52","doi-asserted-by":"crossref","first-page":"27090","DOI":"10.1074\/jbc.M114.580936","article-title":"Shock wave treatment enhances cell proliferation and improves wound healing by ATP release-coupled extracellular signal-regulated kinase (ERK) activation","volume":"289","author":"Weihs","year":"2014","journal-title":"J Biol Chem"},{"issue":"6","key":"10.1016\/j.bj.2022.11.004_bib53","doi-asserted-by":"crossref","first-page":"1226","DOI":"10.1093\/cvr\/cvz209","article-title":"miR-19a-3p containing exosomes improve function of ischaemic myocardium upon shock wave therapy","volume":"116","author":"Gollmann-Tepek\u00f6yl\u00fc","year":"2020","journal-title":"Cardiovasc Res"},{"key":"10.1016\/j.bj.2022.11.004_bib54","doi-asserted-by":"crossref","first-page":"3","DOI":"10.4103\/UROS.UROS_56_21","article-title":"Potential applications of low-intensity extracorporeal shock-wave therapy in urological diseases via activation of tissue resident stem cells","volume":"33","author":"Lue","year":"2022","journal-title":"Urol Sci"},{"issue":"4","key":"10.1016\/j.bj.2022.11.004_bib55","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1034\/j.1600-0501.2003.110770.x","article-title":"Investigation of allogeneic mesenchymal stem cell-based alveolar bone formation: preliminary findings","volume":"14","author":"De Kok","year":"2003","journal-title":"Clin Oral Implants Res"},{"issue":"6","key":"10.1016\/j.bj.2022.11.004_bib56","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1016\/j.jbspin.2011.04.013","article-title":"Interleukin-33: a novel player in osteonecrosis of the femoral head?","volume":"78","author":"Saidi","year":"2011","journal-title":"Jt Bone Spine"},{"issue":"4","key":"10.1016\/j.bj.2022.11.004_bib57","doi-asserted-by":"crossref","first-page":"R139","DOI":"10.1186\/ar4601","article-title":"Extracorporeal shockwave therapy in osteoporotic osteoarthritis of the knee in rats: an experiment in animals","volume":"16","author":"Wang","year":"2014","journal-title":"Arthritis Res Ther"},{"key":"10.1016\/j.bj.2022.11.004_bib58","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/7158014","article-title":"Possible roles of IL-33 in the innate-adaptive immune crosstalk of psoriasis pathogenesis","volume":"2019","author":"Cannav\u00f2","year":"2019","journal-title":"Mediat Inflamm"},{"key":"10.1016\/j.bj.2022.11.004_bib59","doi-asserted-by":"crossref","first-page":"60","DOI":"10.1111\/j.1600-051X.2010.01671.x","article-title":"How has research into cytokine interactions and their role in driving immune responses impacted our understanding of periodontitis?","volume":"38","author":"Preshaw","year":"2011","journal-title":"J Clin Periodontol"},{"key":"10.1016\/j.bj.2022.11.004_bib60","doi-asserted-by":"crossref","first-page":"202","DOI":"10.22203\/eCM.v021a16","article-title":"Roles of inflammatory and anabolic cytokines in cartilage metabolism: signals and multiple effectors converge upon MMP-13 regulation in osteoarthritis","volume":"21","author":"Goldring","year":"2011","journal-title":"Eur Cell Mater"},{"issue":"2","key":"10.1016\/j.bj.2022.11.004_bib61","doi-asserted-by":"crossref","first-page":"595","DOI":"10.1007\/s10753-017-0715-1","article-title":"IL-21 enhances the degradation of cartilage through the JAK-STAT signaling pathway during osteonecrosis of femoral head cartilage","volume":"41","author":"Chen","year":"2017","journal-title":"Inflammation"},{"issue":"9","key":"10.1016\/j.bj.2022.11.004_bib62","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.3390\/cells9091944","article-title":"The expressions of TSLP, IL-33, and IL-17A in monocyte derived dendritic cells from asthma and COPD patients are related to epithelial\u2013macrophage interactions","volume":"9","author":"Paplinska Goryca","year":"2020","journal-title":"Cells"},{"issue":"4","key":"10.1016\/j.bj.2022.11.004_bib63","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0153174","article-title":"Comprehensive genome-wide transcriptomic analysis of immature articular cartilage following ischemic osteonecrosis of the femoral head in piglets","volume":"11","author":"Adapala","year":"2016","journal-title":"PLoS One"},{"issue":"7","key":"10.1016\/j.bj.2022.11.004_bib64","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.joca.2021.04.005","article-title":"Proteomics analysis of hip articular cartilage identifies differentially expressed proteins associated with osteonecrosis of the femoral head","volume":"29","author":"Song","year":"2021","journal-title":"Osteoar Cartil"}],"container-title":["Biomedical Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2319417022001561?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2319417022001561?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T09:14:08Z","timestamp":1762420448000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2319417022001561"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":64,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2023,12]]}},"alternative-id":["S2319417022001561"],"URL":"https:\/\/doi.org\/10.1016\/j.bj.2022.11.004","relation":{},"ISSN":["2319-4170"],"issn-type":[{"value":"2319-4170","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of three clinical therapies on cytokines modulation in the hip articular cartilage and bone improvement in rat early osteonecrosis of the femoral head","name":"articletitle","label":"Article Title"},{"value":"Biomedical Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.bj.2022.11.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 The Authors. Published by Elsevier B.V. on behalf of Chang Gung University.","name":"copyright","label":"Copyright"}],"article-number":"100571"}}